A polypeptide rapid freeze-drying device

Abstract

The utility model provides a polypeptide rapid freeze-drying device, comprising a freeze-drying box, a refrigerator is fixedly connected to the top of the freeze-drying box, an air jet is fixedly connected to the output end of the refrigerator, the air jet extends to the inside of the freeze-drying box, and a plurality of air jet holes are opened on the side wall of the air jet; a test tube rack is clamped on the inner side wall of the freeze-drying box, a plurality of through holes are opened on the test tube rack, and a gear seat is rotatably connected to the top of any through hole; a gear and a gear seat are driven to rotate by a driving motor, and the rotation of the plurality of gear seats drives the test tubes clamped thereon to rotate, thereby evenly freezing the test tubes and accelerating the efficiency of freeze-drying; cold air is sprayed through the plurality of air jet holes on the air jet tube to freeze-dry the polypeptides in the test tubes, and the air jet tube is located in the middle of the plurality of test tubes, and the plurality of air jet holes simultaneously spray cold air to freeze-dry the polypeptides in the plurality of test tubes, thereby greatly improving the efficiency of freeze-drying.

Description

Technical Field

[0001] The utility model belongs to the technical field of polypeptide processing, and in particular relates to a polypeptide rapid freeze-drying device. Background Art

[0002] Polypeptides are compounds formed by α-amino acids linked together by peptide bonds. They are intermediate products of protein hydrolysis. Compounds formed by the dehydration and condensation of two amino acid molecules are called dipeptides. By analogy, there are tripeptides, tetrapeptides, pentapeptides, etc. Compounds formed by the dehydration and condensation of 10-100 amino acid molecules are usually called polypeptides; currently, we often need to freeze-dry the produced polypeptides, such as the "freeze-drying device for polypeptides" with the patent number "CN201920920464.2" published on May 12, 2020. This freeze-drying device includes a freeze-drying box and a refrigeration chamber installed on one side of the top of the freeze-drying box. The interior of the refrigeration chamber is provided with an arch tube, and one end of the arch tube passes through the refrigeration chamber and is equipped with an air inlet hood, and the other end of the arch tube passes through the refrigeration chamber and extends to the interior of the freeze-drying box, where a first refrigeration jet pipe and a second refrigeration jet pipe are respectively installed. , and the second refrigeration jet pipe is located below the first refrigeration jet pipe, a plurality of refrigerators are installed inside the refrigeration chamber, and a temperature conducting plate is installed at the bottom of the refrigerator, a temperature conducting rod is installed at the bottom of the temperature conducting plate, and a fan is provided on the inner side of the air inlet hood; in the above technical scheme, a placement groove is placed on the first sliding plate and the second sliding plate, and a polypeptide is placed in the placement groove, and the fan is started to draw air into the bow-shaped tube in the refrigeration chamber, and the refrigerator is started, and the air in the bow-shaped tube is cooled by the cooperation of the temperature conducting plate and the temperature conducting rod, and then sprayed on the polypeptide in the placement groove through the first refrigeration jet pipe and the second refrigeration jet pipe, so as to perform freeze drying.

[0003] However, the above-mentioned freeze-drying device still has defects, such as uneven cooling of the polypeptide and uneven temperature in the freeze-drying chamber, which greatly reduces the efficiency of polypeptide freeze-drying. Utility Model Content

[0004] In order to overcome the deficiencies in the prior art, the utility model provides a polypeptide rapid freeze-drying device which can cool polypeptides uniformly, maintain uniform temperature in a freeze-drying box, and improve freeze-drying efficiency.

[0005] The technical solution adopted by the utility model to solve the technical problem is: comprising a freeze drying box, a refrigerator is fixedly connected to the top of the freeze drying box, an injection pipe is fixedly connected to the output end of the refrigerator, the injection pipe extends to the interior of the freeze drying box, and a plurality of injection holes are opened on the side wall of the injection pipe;

[0006] A test tube rack is clamped on the inner wall of the freeze drying box, and a plurality of through holes are opened on the test tube rack. A gear seat is rotatably connected to the top of any through hole, and a plurality of gear seats are meshed with each other. A test tube for containing polypeptides is clamped on the gear seat, and the lower part of the test tube passes through the through hole; a partition is fixedly connected to the inner wall of the freeze drying box, and the partition is located at the lower part of the freeze drying box;

[0007] A driving motor is fixedly connected to the bottom end of the freeze drying box, and the driving motor is located below the partition; a rotating rod is fixedly connected to the output end of the driving motor, one end of the rotating rod passes through the partition and extends to the upper part of the freeze drying box, a gear is fixedly connected to the middle part of the rotating rod, and the gear is meshed with the gear seat, and the driving motor drives the rotating rod, the gear and the gear seat to rotate, thereby driving the test tube on the gear seat to rotate; the driving motor drives the gear and the gear seat to rotate, and the rotation of several gear seats drives the test tubes clamped thereon to rotate, thereby evenly freezing the test tubes and accelerating the efficiency of freeze drying; cold air is sprayed through several jet holes on the jet pipe to freeze-dry the polypeptides in the test tubes, and the jet pipe is located in the middle of several test tubes, and several jet holes simultaneously spray cold air to freeze-dry the polypeptides in several test tubes, thereby greatly improving the efficiency of freeze drying.

[0008] It is further configured as follows: a plurality of clamping seats are fixedly connected to the inner side wall of the freeze drying box, a clamping block is fixedly connected to the side wall of the test tube rack, and the clamping seats and the clamping blocks are adapted to each other.

[0009] It is further configured that: the top end of the rotating rod is rotatably connected to the top end inside the freeze drying box.

[0010] It is further configured as follows: a support seat is fixedly connected to the top of the gear seat, and the test tube passes through the support seat.

[0011] It is further configured as follows: a support frame is fixedly connected to the inner wall of the freeze drying box, and the support frame is rotatably connected to the rotating rod; a support frame is fixedly connected to the inner wall of the freeze drying box, and the support frame is rotatably connected to the rotating rod, one end of the support frame located at the bottom is fixed to the top of the partition, and the rotating rod is supported by the support frame to improve the stability of the rotating rod.

[0012] It is further configured as follows: one end of the support frame is fixed on the top end of the partition.

[0013] The invention is further configured as follows: a fan is fixedly connected to the outer wall of the freeze drying box, one end of the fan is connected to an input pipe, and one end of the input pipe extends to the lower inner part of the freeze drying box, and the other end of the fan is connected to an output pipe, one end of the output pipe extends to the upper inner part of the freeze drying box, and one end of the output pipe extends to the inside of the freeze drying box and is connected to the jet pipe; the cold air at the bottom of the freeze drying box is pumped to the upper part by the fan, so as to accelerate the flow of air in the freeze drying box, promote the temperature balance in the freeze drying box, and improve the efficiency of freeze drying.

[0014] It is further configured as follows: one end of the output pipe connected to the jet pipe is tilted downward; one end of the output pipe connected to the jet pipe is tilted downward, and the airflow generated by the fan accelerates the speed of the cold air flowing in the jet pipe.

[0015] The beneficial effects of the utility model are as follows: the gears and the gear seats are driven to rotate by a driving motor, and the rotation of the gear seats drives the test tubes connected thereon to rotate, so that the test tubes can be frozen evenly and the freeze-drying efficiency can be accelerated; the cold air is sprayed through the several jet holes on the jet pipe to freeze-dry the polypeptides in the test tubes, and the jet pipe is located in the middle of the several test tubes, and the several jet holes simultaneously spray cold air to freeze-dry the polypeptides in the several test tubes, thereby greatly improving the freeze-drying efficiency; a support frame is fixedly connected to the inner side wall of the freeze-drying box, and the support frame is rotatably connected to the rotating rod, and one end of the support frame is located at the bottom and is fixed on the top of the partition, and the rotating rod is supported by the support frame to improve the stability of the rotating rod; the cold air at the bottom of the freeze-drying box is pumped to the upper part by the fan, so as to accelerate the flow of air in the freeze-drying box, promote the temperature balance in the freeze-drying box, and improve the freeze-drying efficiency; the end of the outlet pipe connected to the jet pipe is tilted downward, and the airflow generated by the fan accelerates the flow speed of the cold air in the jet pipe. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a structural schematic diagram of the utility model;

[0017] Figure 2 This is a schematic diagram of the test tube rack structure of the utility model;

[0018] In the figure: 1-freeze drying box, 2-refrigerator, 3-jet tube, 4-test tube rack, 5-gear seat, 6-partition, 7-drive motor, 8-rotating rod, 9-gear, 10-clamping block, 11-support seat, 12-support frame, 13-blower, 14-input pipe, 15-output pipe, 16-clamping seat. DETAILED DESCRIPTION

[0019] The utility model is further described below in conjunction with the accompanying drawings:

[0020] Embodiment 1: Figure 1-2As shown: this embodiment includes a freeze drying box 1, a switch door is provided at one end of the freeze drying box 1, and polypeptides can be conveniently taken out through the switch door. A refrigerator 2 is fixedly connected to the top of the freeze drying box 1, and an air jet 3 is fixedly connected to the output end of the refrigerator 2. One end of the air jet 3 extends to the interior of the freeze drying box 1, and a plurality of air jet holes are provided on the side wall of the air jet 3, so that the cold air generated by the refrigerator 2 is sprayed out to freeze-dry the polypeptides in the test tube; a test tube rack 4 is clamped on the inner side wall of the freeze drying box 1, and a A plurality of through holes are provided, and a plurality of gear seats 5 are rotatably connected to the test tube rack 4. The plurality of gear seats 5 are respectively located directly above the corresponding through holes. A support seat 11 is fixedly connected to the top of any gear seat 5. The test tube is clamped on the support seat 11, and the test tube is supported by the support seat 11, and it is convenient to take the test tube; the lower part of the test tube passes through the gear seat 5 and the through hole; a partition 6 is fixedly connected to the inner wall of the freeze drying box 1, and the partition 6 is located below the test tube, and the bottom of the inner side of the freeze drying box 1 A driving motor 7 is fixedly connected to the top, and a rotating rod 8 is fixedly connected to the output end of the driving motor 7. One end of the rotating rod 8 passes through the partition 6 and fits with the top of the inside of the freeze drying box 1, and the rotating rod 8 is rotatably connected to the freeze drying box 1. A gear 9 is fixedly connected to the middle of the rotating rod 8, and the gear 9 is meshed with one of the gear seats 5 among the plurality of gear seats 5. When the freeze drying device is working, the refrigerator 2 starts to produce cold air, and the cold air is transmitted to the jet pipe 3. The cold air is sprayed through the plurality of jet holes on the jet pipe 3 to freeze the polypeptides in the test tube, and the jet pipe 3 is located in the middle position of the plurality of test tubes. The plurality of jet holes simultaneously spray cold air to freeze the polypeptides in the plurality of test tubes, which greatly improves the efficiency of freeze drying. At the same time, the driving motor 7 rotates, driving the rotating rod 8 and the gear 9 fixed on the rotating rod 8 to rotate. The gear 9 rotates and drives the gear seat 5 meshing with it to rotate, and the gear seat 5 drives the other plurality of gear seats 5 to rotate. When the plurality of gear seats 5 rotate, the corresponding test tubes are driven to rotate, thereby evenly freezing the test tubes and accelerating the efficiency of freeze drying.

[0021] A driving motor 7 is fixedly connected to the bottom end of the freeze drying box 1, and the driving motor 7 is located below the partition 6; a rotating rod 8 is fixedly connected to the output end of the driving motor 7, one end of the rotating rod 8 passes through the partition 6 and extends to the upper part of the freeze drying box 1, a gear 9 is fixedly connected to the middle part of the rotating rod 8, and the gear 9 is meshed with the gear seat 5. The driving motor 7 rotates to drive the rotating rod 8, the gear and the gear seat 5 to rotate, thereby driving the test tube on the gear seat 5 to rotate.

[0022] In addition, a plurality of snap-in seats 16 are fixedly connected to the inner wall of the freeze drying box 1, and a plurality of snap-in blocks 10 are fixedly connected to the outer wall of the test tube rack 4. The plurality of snap-in blocks 10 are adapted to the snap-in seats 16, and the test tube rack 4 is snap-connected to the snap-in seats 16 on the freeze drying box 1 through the snap-in blocks 10.

[0023] A support frame 12 is fixedly connected to the inner wall of the freeze drying box 1, and the support frame 12 is rotatably connected to the rotating rod 8. One end of the support frame 12 at the bottom is fixed to the top of the partition 6. The rotating rod 8 is supported by the support frame 12 to improve the stability of the rotating rod 8.

[0024] Embodiment 2: A fan 13 is fixedly connected to the outer wall of the freeze drying box 1, one end of the fan 13 is connected to an input pipe 14, and the other end is fixedly connected to an output pipe 15. One end of the input pipe 14 extends to the lower inner part of the freeze drying box 1, and one end of the output pipe 15 extends to the upper inner part of the freeze drying box 1, and one end of the output pipe 15 extends to the inside of the freeze drying box 1 and is connected to the jet pipe 3. The cold air at the bottom of the freeze drying box 1 is pumped to the upper part by the fan 13, which accelerates the flow of air in the freeze drying box 1, promotes the temperature balance in the freeze drying box 1, and improves the efficiency of freeze drying; the end of the outlet pipe 15 connected to the jet pipe 3 is tilted downward, and the airflow generated by the fan 13 accelerates the speed of the cold air flowing in the jet pipe 3; a temperature sensor is fixedly connected to the inner wall of the freeze drying box 1, and the temperature in the freeze drying box 1 is monitored by the temperature sensor.

[0025] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A polypeptide rapid freeze-drying device, comprising a freeze-drying box (1), a refrigerator (2) fixedly connected to the top of the freeze-drying box (1), an air jet pipe (3) fixedly connected to the output end of the refrigerator (2), characterized in that: The jet pipe (3) extends to the interior of the freeze drying chamber (1), and a plurality of jet holes are provided on the side wall of the jet pipe (3); A test tube rack (4) is clamped on the inner wall of the freeze drying box (1), and a plurality of through holes are opened on the test tube rack (4). A gear seat (5) is rotatably connected to the top of any of the through holes, and the gear seats (5) are meshed with each other. A test tube for containing polypeptides is clamped on the gear seat (5), and the lower part of the test tube passes through the through hole; a partition (6) is fixedly connected to the inner wall of the freeze drying box (1), and the partition (6) is located at the lower part of the freeze drying box (1); A driving motor (7) is fixedly connected to the bottom of the freeze drying box (1), and the driving motor (7) is located below the partition (6); a rotating rod (8) is fixedly connected to the output end of the driving motor (7), one end of the rotating rod (8) passes through the partition (6) and extends to the upper part of the freeze drying box (1), and a gear (9) is fixedly connected to the middle part of the rotating rod (8), and the gear (9) is meshed with the gear seat (5). The driving motor (7) rotates to drive the rotating rod (8), the gear and the gear seat (5) to rotate, thereby driving the test tube on the gear seat (5) to rotate.

2. A polypeptide rapid freeze-drying device according to claim 1, characterized in that: A plurality of clamping seats (16) are fixedly connected to the inner side wall of the freeze drying box (1), a clamping block (10) is fixedly connected to the side wall of the test tube rack (4), and the clamping seats (16) and the clamping blocks (10) are adapted to each other.

3. A polypeptide rapid freeze-drying device according to claim 1, characterized in that: The top end of the rotating rod (8) is rotatably connected to the top end inside the freeze drying box (1).

4. A polypeptide rapid freeze-drying device according to claim 1, characterized in that: A support seat (11) is fixedly connected to the top end of the gear seat (5), and the test tube passes through the support seat (11).

5. A polypeptide rapid freeze-drying device according to claim 1, characterized in that: A support frame (12) is fixedly connected to the inner wall of the freeze drying box (1), and the support frame (12) is rotatably connected to the rotating rod (8).

6. A polypeptide rapid freeze-drying device according to claim 5, characterized in that: One end of the support frame (12) is fixed on the top end of the partition (6).

7. A polypeptide rapid freeze-drying device according to claim 1, characterized in that: A fan (13) is fixedly connected to the outer wall of the freeze drying chamber (1), one end of the fan (13) is connected to an input pipe (14), and one end of the input pipe (14) extends to the lower inner part of the freeze drying chamber (1), and the other end of the fan (13) is connected to an output pipe (15), one end of the output pipe (15) extends to the upper inner part of the freeze drying chamber (1), and one end of the output pipe (15) extends to the inside of the freeze drying chamber (1) and is connected to the jet pipe (3).

8. A polypeptide rapid freeze-drying device according to claim 7, characterized in that: The end of the output pipe (15) connected to the air injection pipe (3) is arranged to be tilted downward.

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