A detection device for nucleic acid extraction reagent

Abstract

The utility model relates to the technical field of nucleic acid detection and discloses a detection device for nucleic acid extraction reagents, comprising a box body, a moving device is fixed on the upper side of the box body, a stirring device is fixed on the box body, a display is arranged on the side of the box body close to the stirring device, a liquid storage tank is arranged above the stirring device, a dropper is connected to the lower side of the liquid storage tank, a partition is fixed on one side of the stirring device, a waste water tank is arranged on the lower part of the side of the partition away from the stirring device, and a cleaning device is fixed above the waste water tank. The utility model has the advantage that the reagent can be poured out by the moving device, and the reagent tube can be moved to the bottom of the cleaning device for cleaning, thereby avoiding the reagent tube contacting the sample during the nucleic acid detection process, which is easy to leave the nucleic acid to be detected. The existing nucleic acid detection device usually lacks the function of thoroughly cleaning the reagent tube after the detection is completed, resulting in potential contamination problems.

Description

Technical Field

[0001] The utility model relates to the technical field of nucleic acid detection, in particular to a detection device for nucleic acid extraction reagents. Background Art

[0002] Nucleic acid testing refers to the technology of simulating DNA amplification in vivo in vitro to conduct corresponding detection. The main technologies currently used are PCR (polymerase chain reaction), LAMP (loop-mediated nucleic acid amplification) and RAA (recombinase-mediated isothermal nucleic acid amplification).

[0003] During the nucleic acid testing process, the reagent tube contacts the sample, and nucleic acid to be tested is likely to remain. Existing nucleic acid testing devices usually lack the function of thoroughly cleaning the reagent tube after the test, which can easily lead to potential contamination problems. Utility Model Content

[0004] In order to solve the above problems, the utility model provides a detection device for nucleic acid extraction reagents, which avoids the reagent tube contacting the sample during the nucleic acid detection process, which easily causes residual nucleic acid to be detected. Existing nucleic acid detection devices usually lack the function of thoroughly cleaning the reagent tube after the detection is completed, which easily leads to potential contamination problems.

[0005] In order to solve the above technical problems, the technical solution provided by the utility model is as follows: a detection device for nucleic acid extraction reagents, comprising a box body, a moving device is fixed on the upper side of the box body, a stirring device is fixed inside the box body, a display is arranged on the side of the box body close to the stirring device, a liquid storage tank is arranged above the stirring device, a dropper is connected to the lower side of the liquid storage tank, a partition is fixed on one side of the stirring device, a wastewater tank is arranged at the lower part of the side of the partition away from the stirring device, and a cleaning device is fixed above the wastewater tank;

[0006] The moving device includes a driving motor 1 fixed on the upper side of the interior of the box body, the output end of the driving motor 1 is connected to a rotating shaft 1, the end of the rotating shaft 1 away from the driving motor 1 is fixed with a bevel gear 1, the bevel gear 1 is meshingly connected with a bevel gear 2, the bevel gear 2 is rotatably connected to a rotating column on the side close to the box body, a screw is fixed to the side of the bevel gear 2 away from the rotating column, a moving column is arranged on the outside of the screw, a driving motor 2 is fixed inside the moving column, the output end of the driving motor 2 is connected to a rotating shaft 2, a driving motor 3 is fixed to the lower end of the rotating shaft 2, the output end of the driving motor 3 is connected to a rotating shaft 3, and a fixed sleeve is fixed to the end of the rotating shaft 3 away from the driving motor 3.

[0007] As an improvement, a threaded hole is provided on the upper portion of the movable column, and the movable column is threadably connected to the screw rod.

[0008] As an improvement, the stirring device includes a driving motor four fixed inside the box body, the output end of the driving motor four is connected to a rotating shaft four, and a detection barrel is fixed on the top of the rotating shaft four.

[0009] As an improvement, the cleaning device includes a cleaning box fixed on the upper side of the box body, a drain pipe is connected to the lower side of the cleaning box, and a plurality of nozzles are arranged on the lower side of the drain pipe.

[0010] As an improvement, control valves are provided inside the drip pipe and the drain pipe.

[0011] As an improvement, a pipe inlet is provided on the upper part of the box body close to the moving device.

[0012] The advantage of the utility model over the prior art is that the reagent can be poured out through the moving device, and the reagent tube can be moved to the bottom of the cleaning device for cleaning, thereby avoiding the reagent tube contacting the sample during the nucleic acid detection process, which easily leads to residual nucleic acid to be detected. The existing nucleic acid detection devices usually lack the function of thoroughly cleaning the reagent tube after the detection is completed, which easily leads to potential contamination problems. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is the overall structural front view of the utility model.

[0014] Figure 2 It is a side view of the overall structure of the utility model.

[0015] As shown in the figure: 1. Box body; 2. Pipe inlet; 3. Moving device; 301. Driving motor 1; 302. Rotating shaft 1; 303. Bevel gear 1; 304. Bevel gear 2; 305. Rotating column; 306. Screw; 307. Moving column; 308. Driving motor 2; 309. Rotating shaft 2; 310. Driving motor 3; 311. Rotating shaft 3; 312. Fixed sleeve; 4. Stirring device; 401. Driving motor 4; 402. Rotating shaft 4; 403. Detection barrel; 5. Liquid storage tank; 6. Dropper; 7. Partition; 8. Cleaning device; 801. Cleaning box; 802. Drain pipe; 803. Sprinkler; 9. Wastewater tank; 10. Display. DETAILED DESCRIPTION

[0016] The utility model is further described in detail below in conjunction with the accompanying drawings.

[0017] In the specific implementation of the utility model, Figure 1 to Figure 2 A detection device for nucleic acid extraction reagents, comprising a box body 1, a moving device 3 is fixed on the upper side of the box body 1, and a pipe inlet 2 is arranged on the upper side of the box body 1 near the moving device 3;

[0018] The moving device 3 includes a driving motor 1 301 fixed on the upper side of the box body 1, the output end of the driving motor 1 301 is connected to a rotating shaft 1 302, a bevel gear 1 303 is fixed to the end of the rotating shaft 1 302 away from the driving motor 1 301, the bevel gear 1 303 is meshedly connected to a bevel gear 2 304, the bevel gear 2 304 is rotatably connected to a rotating column 305 on the side close to the box body 1, and a screw 306 is fixed to the side of the bevel gear 2 304 away from the rotating column 305, and the screw 306 is externally connected to the screw 306. A moving column 307 is arranged on the side, a threaded hole is arranged on the upper part of the moving column 307, the moving column 307 is threadedly connected with the screw rod 306, a second driving motor 308 is fixed inside the moving column 307, the output end of the second driving motor 308 is connected with a second rotating shaft 309, a third driving motor 310 is fixed at the lower end of the second rotating shaft 309, the output end of the third driving motor 310 is connected with a third rotating shaft 311, and a fixed sleeve 312 is fixed at one end of the third rotating shaft 311 away from the third driving motor 310;

[0019] During the implementation of the utility model, the reagent tube is placed inside the fixed sleeve 312, and the driving motor three 310 is started, so that the rotating shaft three 311 drives the reagent tube to tilt, and the internal reagent is poured into the detection barrel 403. After the pouring is completed, the driving motor one 301 is started, so that the rotating shaft one 302 drives the bevel gear one 303 to rotate, and drives the meshing bevel gear two 304 to rotate, so that the screw 306 rotates to drive the moving column 307 to move, and the driving motor two 308 is started to rotate the rotating shaft two 306, and the fixed sleeve 312 is moved to the other side of the partition 7 to clean the reagent tube.

[0020] A stirring device 4 is fixed inside the box 1, a liquid storage tank 5 is arranged above the stirring device 4, a dropper 6 is connected to the lower side of the liquid storage tank 5, the stirring device 4 includes a driving motor 401 fixed inside the box 1, the output end of the driving motor 401 is connected to a rotating shaft 402, a detection barrel 403 is fixed on the top of the rotating shaft 402, and a display 10 is arranged on the side of the box 1 close to the stirring device 4;

[0021] During the implementation of the utility model, the detection liquid is dripped into the detection barrel 403 through the dropper 6, and the driving motor 401 is started, so that the rotating shaft 402 drives the detection barrel 403 to rotate, the internal liquid is stirred evenly, and the detection result is viewed through the display 10.

[0022] A partition 7 is fixed on one side of the stirring device 4, a waste water tank 9 is arranged at the lower part of the partition 7 away from the stirring device 4, a cleaning device 8 is fixed above the waste water tank 9, the cleaning device 8 comprises a cleaning box 801 fixed on the upper side of the box body 1, a drain pipe 802 is connected to the lower side of the cleaning box 801, control valves are arranged inside the dripping pipe 6 and the drain pipe 802, and a plurality of nozzles 803 are arranged on the lower side of the drain pipe 802;

[0023] During the implementation of the utility model, the empty reagent tube is moved to the bottom of the cleaning box 801, and the reagent tube is flushed through the nozzle 803 of the drainage pipe 802. The cleaned waste water flows into the waste water tank 9, and the reagent tube is discharged from the box body 1 through the pipe inlet 2 to prevent pollution to the outside.

[0024] The above description of the utility model and its implementation methods is not restrictive. The drawings show only one implementation method of the utility model, and the actual structure is not limited thereto. In short, if ordinary technicians in this field are inspired by it and design structural methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention of the utility model, they should all fall within the protection scope of the utility model.

Claims

1. A detection device for nucleic acid extraction reagents, characterized in that: The invention comprises a box (1), wherein a moving device (3) is fixed on the upper side of the box (1), a stirring device (4) is fixed on the inside of the box (1), a display (10) is arranged on the side of the box (1) close to the stirring device (4), a liquid storage tank (5) is arranged above the stirring device (4), a dropper (6) is connected to the lower side of the liquid storage tank (5), a partition (7) is fixed on one side of the stirring device (4), a waste water tank (9) is arranged on the lower part of the side of the partition (7) away from the stirring device (4), and a cleaning device (8) is fixed above the waste water tank (9); The moving device (3) comprises a driving motor 1 (301) fixed on the upper side of the interior of the housing (1); the output end of the driving motor 1 (301) is connected to a rotating shaft 1 (302); a bevel gear 1 (303) is fixed to the end of the rotating shaft 1 (302) away from the driving motor 1 (301); the bevel gear 1 (303) is meshingly connected to a bevel gear 2 (304); the bevel gear 2 (304) is rotatably connected to a rotating column (305) on a side close to the housing (1); the bevel gear 2 (304) is away from the rotating column (305). A screw rod (306) is fixed on one side, a movable column (307) is arranged on the outside of the screw rod (306), a driving motor 2 (308) is fixed inside the movable column (307), the output end of the driving motor 2 (308) is connected to a rotating shaft 2 (309), a driving motor 3 (310) is fixed to the lower end of the rotating shaft 2 (309), the output end of the driving motor 3 (310) is connected to a rotating shaft 3 (311), and a fixed sleeve (312) is fixed to one end of the rotating shaft 3 (311) away from the driving motor 3 (310).

2. A detection device for nucleic acid extraction reagent according to claim 1, characterized in that: A threaded hole is provided on the upper portion of the movable column (307), and the movable column (307) is threadedly connected to the screw rod (306).

3. A detection device for nucleic acid extraction reagent according to claim 1, characterized in that: The stirring device (4) comprises a driving motor four (401) fixed inside the box body (1), the output end of the driving motor four (401) is connected to a rotating shaft four (402), and a detection barrel (403) is fixed to the top of the rotating shaft four (402).

4. A detection device for nucleic acid extraction reagent according to claim 1, characterized in that: The cleaning device (8) comprises a cleaning box (801) fixed on the upper side of the box body (1); a drainage pipe (802) is connected to the lower side of the cleaning box (801); and a plurality of nozzles (803) are arranged on the lower side of the drainage pipe (802).

5. A detection device for nucleic acid extraction reagent according to claim 4, characterized in that: Control valves are provided inside the dripping pipe (6) and the drainage pipe (802).

6. A detection device for nucleic acid extraction reagent according to claim 1, characterized in that: A pipe inlet (2) is provided on the upper part of the box body (1) near the moving device (3).

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