A high-precision injection pump

Abstract

The utility model relates to the field of drug dissolution test equipment, and specifically discloses a high-precision injection pump, comprising an injection pump housing, a stepping motor, a lead screw structure and an injector. A partition is arranged in the injection pump housing, a guide column is arranged on the partition, one end of the guide column is connected with the top of the injection pump housing, a synchronous block is sleeved on the outer periphery of the guide column, a circular hole is arranged in the middle of the synchronous block, the lead screw structure is fixedly connected with the inner wall of the circular hole, one end of the lead screw structure is rotatably connected with the top of the injection pump housing, the lead screw structure rotates synchronously with the stepping motor, the top of the injector is connected with the synchronous block, an electromagnetic valve is arranged at the bottom of the injector, the lead screw can be driven to rotate by the stepping motor, the lead screw rotates the synchronous block up and down, and the injector connected with the synchronous block works synchronously, so as to avoid the problem that uneven force and imbalance of the injector cause deformation of the guide column, increase friction between the syringe and the piston, and shorten the service life of the syringe.

Description

Technical Field

[0001] The utility model relates to the field of drug dissolution test equipment, in particular to a high-precision injection pump. Background Art

[0002] With the rapid development of pharmaceutical technology, the emergence of a large number of new dosage forms and the current requirements for in vitro and in vivo correlation of dissolution test methods, traditional dissolution test methods (basket method, paddle method, etc.) encounter many new problems and difficulties in the quality control of preparations, such as the determination of trace drug preparations, microspheres, immediate release preparations, etc. As a new dissolution test method, the flow cell method can be used for the dissolution and release of special dosage forms such as powders, suppositories, granules, suspensions, microspheres and drug eluting stents in addition to the dissolution test of traditional solid oral preparations. It avoids the disadvantages of dissolution difficulties and mechanical stirring caused by adsorption equilibrium in existing dissolution test methods. It is especially suitable for the dissolution study of poorly soluble drugs, can better simulate the physiological environment in the body, and has more discriminating power.

[0003] The flow rate in the circulation pool is regulated by the syringe pump. Most of the existing syringe pump bodies adopt a square design. For example, a multi-channel sampling syringe pump with patent number 2014202511327 improves work efficiency by arranging multiple syringe pumps. However, this structure can easily cause uneven force and imbalance on the syringe, which in turn causes the guide column to deform due to uneven force and become unusable. It can also cause great friction between the syringe sealing block and the inner wall of the glass, resulting in a short service life. Utility Model Content

[0004] The utility model is to solve the technical problems mentioned in the above background technology, and proposes the following technical solutions:

[0005] A high-precision injection pump comprises an injection pump housing, a stepper motor, a lead screw structure and an injector, wherein a partition is arranged horizontally in the injection pump housing, a through hole and an injector mounting groove are arranged on the partition, two guide pillars are arranged symmetrically above the partition, one end of the two guide pillars is fixedly connected to the top of the partition, and the other end of the guide pillar is fixedly connected to the top of the injection pump housing, the outer periphery of the two guide pillars is sleeved with a synchronization block, a circular hole is arranged in the middle of the synchronization block, the outer periphery of the lead screw structure is fixedly connected to the inner wall of the circular hole, one end of the lead screw structure is rotatably connected to the top of the injection pump housing, the other end of the lead screw structure passes through the through hole and is located below the partition, a driven wheel is arranged on the outer periphery of the other end of the lead screw structure, the stepper motor is fixed on the inner wall of the injection pump housing, the stepper motor is located below the partition, one end of the stepper motor is fixedly arranged with a driving wheel, the outer periphery of the driving wheel and the driven wheel is sleeved with a synchronous belt, the top of the injector is connected to the synchronization block, and the bottom of the injector is connected with an electromagnetic valve.

[0006] Preferably, the injector comprises a syringe, a piston and a piston rod, the top of the syringe is fixedly mounted in the injector mounting groove, the piston is located in the syringe, one end of the piston is connected to the piston rod, and one end of the piston rod is fixedly connected to the bottom of the synchronization block.

[0007] Preferably, the outer peripheral fixing sleeve of the guide column has an upper positioning ring and a lower positioning ring, the upper positioning ring is located above the synchronization block, and the lower positioning ring is located below the synchronization block.

[0008] Preferably, the screw structure includes a screw and a nut, the outer periphery of the nut is fixedly connected to the inner wall of the circular hole, and the screw is threadedly connected to the nut.

[0009] The beneficial effects of the utility model are:

[0010] 1. The utility model provides a lead screw structure and a stepper motor, and the stepper motor drives the lead screw to rotate. The rotation of the lead screw drives a synchronous block fixedly connected to a nut to move up and down. The piston rods of multiple injectors are connected to the synchronous block, so that the synchronous movement of multiple pistons can be achieved, thereby avoiding the problem that the guide column is deformed due to uneven force and imbalance of the injectors, resulting in increased friction between the syringe and the piston, and shortening the service life of the syringe.

[0011] 2. By setting the upper locating ring and the lower locating ring on the guide column, the stroke of the piston can be set to avoid the pump body being damaged due to exceeding the stroke. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a schematic diagram of the structure of the utility model;

[0013] Figure 2 for Figure 1 Enlarged image of the middle circle;

[0014] Figure 3 This is an oblique view of the utility model;

[0015] Figure 4 for Figure 3 Enlarged image of the circle in the middle.

[0016] In the figure: 1. injection pump housing; 2. stepper motor; 3. screw structure; 3-1. screw; 3-2. nut; 4. injector; 4-1. syringe; 4-2. piston; 4-3. piston rod; 5. partition; 5-1. through hole; 5-2. injector mounting groove; 6. guide column; 6-1. upper positioning ring; 6-2. lower positioning ring; 7. synchronization block; 7-1. round hole; 8. driven wheel; 9. driving wheel; 10. synchronization belt; 11. solenoid valve. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0018] In the description of the present utility model, it is to be understood that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. The connection methods described in the terms "fixed connection" and "fixed arrangement" include but are not limited to "welding", "riveting", "adhesion", and "threaded connection". The terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0019] The directions or positional relationships indicated by terms such as “upper”, “lower”, “front”, “back”, “left”, “right”, “top”, “bottom”, “inside” and “outside” are based on the directions or positional relationships shown in the accompanying drawings and are only for the convenience of describing the present invention and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, they should not be understood as limiting the present invention.

[0020] Embodiment 1

[0021] Reference Figure 1-3 A high-precision injection pump comprises an injection pump housing 1, a stepping motor 2, a lead screw structure 3 and an injector 4. A partition 5 is arranged horizontally in the injection pump housing 1. A through hole 5-1 and an injector mounting groove 5-2 are arranged on the partition 5. Two guide pillars 6 are arranged symmetrically above the partition 5. One end of the two guide pillars 6 is fixedly connected to the top of the partition 5, and the other end of the guide pillars 6 is fixedly connected to the top of the injection pump housing 1. The outer periphery of the two guide pillars 6 is sleeved with a synchronization block 7. A circular hole 7-1 is arranged in the middle of the synchronization block 7. The outer periphery of the lead screw structure 3 is connected to the circular The inner wall of hole 7-1 is fixedly connected, one end of the screw structure 3 is rotatably connected to the top of the injection pump housing 1, the other end of the screw structure 3 passes through the through hole 5-1 and is located below the partition 5, a driven wheel 8 is arranged on the outer periphery of the other end of the screw structure 3, the stepper motor 2 is fixed on the inner wall of the injection pump housing 1, the stepper motor 2 is located below the partition 5, a driving wheel 9 is fixedly arranged at one end of the stepper motor 2, a synchronous belt 10 is sleeved on the outer periphery of the driving wheel 9 and the driven wheel 8, the top of the injector 4 is connected to the synchronization block 7, and the bottom of the injector 4 is connected to the solenoid valve 11.

[0022] Preferably, the injector 4 includes a syringe 4-1, a piston 4-2 and a piston rod 4-3, the top of the syringe 4-1 is fixedly mounted in the injector mounting groove 5-2, the piston 4-2 is located in the syringe 4-1, one end of the piston 4-2 is connected to the piston rod 4-3, and one end of the piston rod 4-3 is fixedly connected to the bottom of the synchronization block 7.

[0023] Preferably, an upper positioning ring 6 - 1 and a lower positioning ring 6 - 2 are fixedly sleeved on the outer periphery of the guide column 6 , the upper positioning ring 6 - 1 is located above the synchronization block 7 , and the lower positioning ring 6 - 2 is located below the synchronization block 7 .

[0024] Preferably, the screw structure 3 includes a screw 3-1 and a nut 3-2, the outer periphery of the nut 3-2 is fixedly connected to the inner wall of the circular hole 7-1, and the screw 3-1 is threadedly connected to the nut 3-2.

[0025] During actual operation, the staff can control the rotation of the stepper motor 2 to control the rotation of the driven wheel 8 that rotates synchronously with the driving wheel 9 on the stepper motor 2. The rotation of the driven wheel 8 will drive the screw 3-1 to rotate. When the screw 3-1 rotates, the nut 3-2 threadedly connected to the screw 3-1 will move up and down, and at the same time drive the synchronous block 7 fixed to the nut 3-2 to move up and down. After the synchronous block 7 is moved, it will drive the piston rod 4-3 to move up and down, and the piston rod will drive the piston 4-2 to move up and down in the syringe 4-1, thereby realizing the synchronous control of the flow rate of the solution in the circulation pool.

Claims

1. A high-precision syringe pump, comprising a syringe pump housing (1), a stepping motor (2), a lead screw structure (3) and a plurality of injectors (4), characterized in that: A partition (5) is arranged at a horizontal position in the injection pump housing (1), and a through hole (5-1) and a plurality of injector mounting grooves (5-2) are arranged on the partition (5). A guide column (6) is symmetrically arranged above the partition (5), and one end of the guide column (6) is fixedly connected to the top of the partition (5), and the other end of the guide column (6) is fixedly connected to the top of the injection pump housing (1). A synchronization block (7) is sleeved on the outer periphery of the guide column (6), and a circular hole (7-1) is arranged in the middle of the synchronization block (7). The outer periphery of the screw structure (3) is fixedly connected to the inner wall of the circular hole (7-1), and one end of the screw structure (3) is fixedly connected to the injection The top of the pump housing (1) is rotatably connected, the other end of the screw structure (3) passes through the through hole (5-1) and is located below the partition (5), and a driven wheel (8) is arranged on the outer periphery of the other end of the screw structure (3). The stepper motor (2) is fixed on the inner wall of the injection pump housing (1), and the stepper motor (2) is located below the partition (5). A driving wheel (9) is fixedly arranged at one end of the stepper motor (2), and a synchronous belt (10) is sleeved on the outer periphery of the driving wheel (9) and the driven wheel (8). The top of the injector (4) is connected to the synchronous block (7), and the bottom of the injector (4) is connected to an electromagnetic valve (11).

2. A high-precision injection pump according to claim 1, characterized in that: The injector (4) comprises a syringe (4-1), a piston (4-2) and a piston rod (4-3); the top of the syringe (4-1) is fixedly mounted in the injector mounting groove (5-2); the piston (4-2) is located in the syringe (4-1); one end of the piston (4-2) is connected to the piston rod (4-3); and one end of the piston rod (4-3) is fixedly connected to the bottom of the synchronization block (7).

3. A high-precision injection pump according to claim 2, characterized in that: The outer peripheral fixed sleeve of the guide column (6) comprises an upper positioning ring (6-1) and a lower positioning ring (6-2); the upper positioning ring (6-1) is located above the synchronization block (7), and the lower positioning ring (6-2) is located below the synchronization block (7).

4. A high-precision injection pump according to claim 2, characterized in that: The lead screw structure (3) comprises a lead screw (3-1) and a nut (3-2); the outer periphery of the nut (3-2) is fixedly connected to the inner wall of the circular hole (7-1); and the lead screw (3-1) and the nut (3-2) are threadedly connected.

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