An electron-proton double resonance imaging detection probe

Abstract

This utility model discloses an electron-proton dual resonance imaging detection probe, including a dual resonance probe cover, a metal film attached to the bottom of the dual resonance probe cover, an insulating plate disposed on the top of the dual resonance probe cover, an imaging gradient coil disposed on the top of the insulating plate, a dual resonance probe resonant cavity installed below the dual resonance probe cover, and a cylindrical resonant cavity formed inside the dual resonance probe cover. This electron-proton dual resonance imaging detection probe, through the coordinated use of the imaging gradient coil, the dual resonance probe resonant cavity, the cylindrical resonant cavity, the microwave coupling hole, and the magnetic resonance radio frequency coil, utilizes electron spin resonance to enhance nuclear magnetic resonance imaging images, which can significantly improve the nuclear magnetic resonance signal and improve the quality of nuclear magnetic resonance imaging. Combining these two technologies in a single imaging probe, this complementarity allows dual resonance imaging detection to provide more comprehensive and detailed molecular structure and dynamics information, with high overall sensitivity.

Description

Technical Field

[0001] The utility model relates to the technical field related to nuclear magnetic resonance, in particular to an electron-proton double resonance imaging detection probe. Background Art

[0002] Magnetic resonance imaging uses the principle of nuclear magnetic resonance. Based on the different attenuation of the released energy in different structural environments inside matter, the emitted electromagnetic waves are detected by applying an external gradient magnetic field. The position and type of the atomic nuclei that make up the object can be known, and the internal structure of the object can be drawn based on this. Applying this technology to imaging the internal structure of the human body has produced a revolutionary medical diagnostic tool. The application of rapidly changing gradient magnetic fields has greatly accelerated the speed of nuclear magnetic resonance imaging, making the application of this technology in clinical diagnosis and scientific research a reality, and greatly promoting the rapid development of medicine, neurophysiology and cognitive neuroscience.

[0003] When the magnetic resonance imaging detection probe is used, the intensity of the nuclear magnetic resonance signal may be weak, resulting in poor detection effect. Therefore, the present application provides an electron proton double resonance imaging detection probe to meet the needs. Utility Model Content

[0004] The purpose of the utility model is to provide an electron proton double resonance imaging detection probe to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an electron proton double resonance imaging detection probe, comprising a double resonance probe cover, a metal film is bonded to the bottom of the double resonance probe cover, an insulating plate is arranged above the double resonance probe cover, an imaging gradient coil is arranged above the insulating plate, a double resonance probe resonant cavity is installed below the double resonance probe cover, a cylindrical resonant cavity is opened inside the double resonance probe resonant cavity, a microwave coupling hole is opened on one side of the cylindrical resonant cavity, and a magnetic resonance radio frequency coil is installed inside the cylindrical resonant cavity.

[0006] Preferably, the metal film is connected to the dual resonance probe cover by adhesive bonding, and the metal film is in close contact with the dual resonance probe cover.

[0007] Preferably, the insulating plate is made of an epoxy plate, and the insulating plate has the same size as the metal film.

[0008] Preferably, a glass tube runs through one side of the resonant cavity of the double resonance probe, and a test sample is arranged inside the glass tube.

[0009] Preferably, four magnetic resonance radio frequency coils are provided, and the magnetic resonance radio frequency coils are distributed in parallel.

[0010] Compared with the prior art, the beneficial effects of the utility model are:

[0011] 1. This electron proton double resonance imaging detection probe, through the coordinated use of imaging gradient coils, double resonance probe resonant cavities, cylindrical resonant cavities, microwave coupling holes and magnetic resonance radio frequency coils, utilizes electron spin resonance to enhance nuclear magnetic resonance imaging images, can greatly enhance nuclear magnetic resonance signals, and improves the quality of nuclear magnetic resonance imaging. The two technologies are combined in one imaging probe. This complementarity enables double resonance imaging detection to provide more comprehensive and detailed molecular structure and dynamics information, and has a higher overall sensitivity. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0013] Figure 2 This is a schematic diagram of the structure of the double resonance probe cover of the utility model;

[0014] Figure 3 It is a schematic diagram of the structure of the resonant cavity of the double resonance probe of the utility model.

[0015] In the figure: 1. Double resonance probe cover; 2. Metal film; 3. Insulation plate; 4. Imaging gradient coil; 5. Double resonance probe resonant cavity; 6. Glass tube; 7. Test sample; 8. Cylindrical resonant cavity; 9. Microwave coupling hole; 10. Magnetic resonance radio frequency coil. DETAILED DESCRIPTION

[0016] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0017] See also Figure 1-2 The utility model provides a technical solution: an electron proton double resonance imaging detection probe, comprising a double resonance probe cover 1, a metal film 2 is attached to the bottom of the double resonance probe cover 1, the metal film 2 and the double resonance probe cover 1 are connected by adhesive, the metal film 2 and the double resonance probe cover 1 are in close contact, the metal film 2 can shield microwaves and the cylindrical resonant cavity 8 is in close contact to form a microwave resonant cavity, an insulating plate 3 is arranged above the double resonance probe cover 1, the material of the insulating plate 3 is an epoxy plate, the insulating plate 3 and the metal film 2 have the same size, the insulating plate 3 is made of epoxy plate to ensure the accuracy of shielding the metal film, an imaging gradient coil 4 is arranged above the insulating plate 3, and a double resonance probe resonant cavity 5 is installed below the double resonance probe cover 1;

[0018] See also Figure 1 and Figure 3 A glass tube 6 runs through one side of the dual resonance probe resonant cavity 5, and a test sample 7 is arranged inside the glass tube 6. The glass tube 6 is used to place the test sample 7. The glass tube 6 is inserted into the dual resonance probe resonant cavity 5 for detection. A cylindrical resonant cavity 8 is opened inside the dual resonance probe resonant cavity 5, and a microwave coupling hole 9 is opened on one side of the cylindrical resonant cavity 8. A magnetic resonance radio frequency coil 10 is installed inside the cylindrical resonant cavity 8. Four magnetic resonance radio frequency coils 10 are arranged, and the magnetic resonance radio frequency coils 10 are distributed in parallel. The use of electron spin resonance to enhance the nuclear magnetic resonance imaging image can greatly improve the nuclear magnetic resonance signal and improve the quality of nuclear magnetic resonance imaging. The two technologies are combined in one imaging probe. This complementarity enables dual resonance imaging detection to provide more comprehensive and detailed molecular structure and dynamics information.

[0019] Working principle: When using the electron proton double resonance imaging detection probe, first put the test sample 7 into the glass tube 6, insert the glass tube 6 into the double resonance probe resonant cavity 5, and then cover the double resonance probe cover 1. The metal film 2 is used to shield microwaves, which improves the insulation effect of the insulating plate 3. During the detection, the electron spin resonance is used to enhance the nuclear magnetic resonance imaging image, which can greatly improve the nuclear magnetic resonance signal, and the double resonance imaging detection can provide more comprehensive and detailed molecular structure and dynamics information. In this way, the use process of the electron proton double resonance imaging detection probe is completed.

[0020] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An electron proton double resonance imaging detection probe, comprising a double resonance probe cover (1), characterized in that: A metal film (2) is bonded to the bottom of the dual resonance probe cover (1), an insulating plate (3) is arranged above the dual resonance probe cover (1), an imaging gradient coil (4) is arranged above the insulating plate (3), a dual resonance probe resonant cavity (5) is installed below the dual resonance probe cover (1), a cylindrical resonant cavity (8) is provided inside the dual resonance probe resonant cavity (5), a microwave coupling hole (9) is provided on one side of the cylindrical resonant cavity (8), and a magnetic resonance radio frequency coil (10) is installed inside the cylindrical resonant cavity (8).

2. The electron proton double resonance imaging detection probe according to claim 1, characterized in that: The metal film (2) and the dual resonance probe cover (1) are connected by adhesive bonding, and the metal film (2) and the dual resonance probe cover (1) are in close contact.

3. The electron proton double resonance imaging detection probe according to claim 1, characterized in that: The insulating plate (3) is made of an epoxy plate, and the insulating plate (3) has the same size as the metal film (2).

4. The electron proton double resonance imaging detection probe according to claim 1, characterized in that: A glass tube (6) passes through one side of the double resonance probe resonant cavity (5), and a detection sample (7) is arranged inside the glass tube (6).

5. The electron proton double resonance imaging detection probe according to claim 1, characterized in that: Four magnetic resonance radio frequency coils (10) are provided, and the magnetic resonance radio frequency coils (10) are distributed in parallel.

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