Suit for macaque percutaneous acupoint electrical stimulation experiment

Abstract

The utility model discloses a suit for macaque percutaneous acupoint electrical stimulation experiment, which comprises an upper garment, a needle therapy instrument, a headgear and a helmet, the needle therapy instrument is fixedly arranged on the outer side of the back of the upper garment, the needle therapy instrument is connected with a stimulating electrode and a detection electrode, the stimulating electrode and the detection electrode are fixed on the headgear, the headgear is sleeved on the head of a macaque in an attached manner, and the helmet is arranged on the headgear. The stimulation electrode can stimulate acupoints of the head of the macaque, and the detection electrode can detect brain wave signals; the helmet can be arranged outside the head sleeve in a sleeving mode and is connected with the neck of the macaque in a clamped mode. The needle therapy instrument is connected with the power supply assembly, and the power supply assembly can provide current for the stimulation electrode and the detection electrode; the needle therapy instrument is connected with the wireless communication module, and the needle therapy instrument can be remotely controlled through the wireless communication module, and changes of brain waves can be remotely received and recorded in real time. The mode that the coat, the head sleeve and the helmet are combined is adopted, the electrode wires are arranged in the helmet and the coat, the phenomenon that the electrodes are pulled by the macaque in the experiment process is avoided, and the experiment reliability is guaranteed.

Description

Technical Field

[0001] The utility model relates to the field of transcutaneous nerve electrical stimulation, in particular to a suit for a macaque transcutaneous acupoint electrical stimulation experiment. Background Art

[0002] Major Depressive Disorder (MDD) is a complex mental illness characterized by low mood, loss of interest, and decreased energy. According to an official report by the World Health Organization (WHO) in 2017, the global incidence of depression accounts for 4.3% of the total population, and is increasing year by year. MDD brings great burdens to society, families, and individuals. This disease has become the number one non-fatal disabling disease. The prevention and treatment of MDD has become a major problem that needs to be solved in the health field of my country and even the world. For the prevention and treatment of MDD, although there are more and more antidepressant drugs available for clinical use today, 40%-50% of patients still do not respond to antidepressant treatment, and antidepressant treatment has large side effects and poor compliance. Therefore, when antidepressant treatment cannot meet clinical needs, it is particularly urgent to seek effective non-drug therapies.

[0003] Acupuncture is an important part of traditional Chinese medicine. As a non-drug intervention, it has been used to treat MDD since ancient times. In recent years, reviews and meta-analyses on acupuncture treatment for MDD have shown that it is a safe and effective antidepressant. Neuromodulation therapy is a new non-drug treatment strategy spawned by the development of neuroscience in recent years. Vagus nerve stimulation (VNS) and trigeminal nerve stimulation (TNS) therapy, which currently belong to its category, have been used in the study of treating MDD. In China, acupuncture anti-depression currently mostly uses head acupoints and ear acupoints. Baihui and Yintang are the two main acupoints recommended for anti-depression treatment in the "Guidelines for Evidence-Based Acupuncture Clinical Practice-Depression". A lot of experiments are needed to understand how to electrically stimulate these two acupoints to effectively relieve depressive symptoms.

[0004] During the experiment, macaques are mostly used for electrical stimulation experiments. However, macaques are active and easy to scratch the equipment. Therefore, they have high requirements for the firmness of the electrode fixation and the comfort of the acupuncture equipment. Therefore, it is necessary to design an instrument for macaque transcutaneous electrical nerve stimulation experiments to ensure the accuracy of the experimental results. Then, it will be studied for the treatment of mental and neurological diseases such as depression, epilepsy and insomnia, so that patients can get rid of the disease as soon as possible. Utility Model Content

[0005] The utility model provides a suit for a macaque transcutaneous electrical acupoint stimulation experiment, which is comfortable to wear, easy to use, and can prevent the macaque from scratching the electrodes. The specific technical solution is as follows:

[0006] A suit for percutaneous electrical acupoint stimulation experiments on macaques, comprising a top, an acupuncture therapy instrument, a head cover and a helmet. The acupuncture therapy instrument is fixedly arranged on the outer side of the back of the top, and a stimulation electrode and a detection electrode are connected to the acupuncture therapy instrument, which are fixed on the head cover. The head cover is snugly mounted on the head of the macaque, and the stimulation electrode can stimulate the acupuncture points on the head of the macaque, and the detection electrode can detect brain wave signals; the helmet can be mounted on the outside of the head cover and snapped onto the neck of the macaque; the acupuncture therapy instrument is connected to a power supply component, which can provide current for the stimulation electrode and the detection electrode; the acupuncture therapy instrument is connected to a wireless communication module, and the acupuncture therapy instrument can be remotely controlled through the wireless communication module, and changes in brain waves can be remotely received and recorded in real time.

[0007] Furthermore, the stimulation electrodes and the detection electrodes are connected to the acupuncture device via wires, the wires pass through the back of the top and are connected to the acupuncture device, and the wires are arranged on the inside of the top.

[0008] Furthermore, the hood is a 3D printed one-piece structure.

[0009] Furthermore, a strap is provided under the head cover, and the strap can be snapped into the lower jaw of the macaque.

[0010] Furthermore, an openable and closable neck ring is arranged under the helmet, and an elastic ring is fixedly arranged on the inner side of the neck ring, and the elastic ring can contact the neck of the macaque.

[0011] Furthermore, the neck collar includes a semi-circular fixed part and a movable part, the fixed part is fixedly connected to the bottom of the helmet, one end of the movable part is hinged to the fixed part, and the other end of the movable part is detachably connected to the fixed part, and the opening and closing of the neck collar is achieved by rotating the movable part.

[0012] Furthermore, an eyepiece is provided at a position on the front side of the helmet corresponding to the face of the macaque, and a VR display screen is provided on the eyepiece.

[0013] Furthermore, the helmet is also equipped with a Bluetooth headset at a position corresponding to the macaque's ear to increase the functions of noise reduction and music playback.

[0014] Furthermore, there are two stimulation electrodes, which are respectively set at the Baihui point on the top of the head and the Yintang point between the eyebrows.

[0015] Furthermore, the detection electrode is set on the forehead or behind the ear of the macaque.

[0016] The utility model discloses a suit for macaque transcutaneous electrical acupoint stimulation experiment, which is cleverly designed and easy to operate. It adopts a combination of a coat, a head cover and a helmet, and the electrode wires are routed inside the helmet and the coat, which prevents the macaque from pulling off the stimulation electrode and the detection electrode during the experiment, thereby ensuring the reliability of the experiment. By providing an openable and closable neck ring, on the one hand, the convenience of wearing the helmet is improved, and on the other hand, the zipper head can be hidden in the neck ring to prevent the macaque from pulling the zipper. In addition, an elastic ring is provided in the neck ring, which improves the comfort of the macaque in wearing the suit. Finally, the sticky fixing components on the stimulation electrode and the detection electrode can further fix the electrodes, which greatly improves the reliability of the electrode work and the effectiveness of electrical stimulation. At the same time, because the elastic sticky ring contacts the skin, the squeezing feeling of the electrode head is reduced, thereby increasing the comfort.

[0017] The above description is only an overview of the technical solution of the utility model. In order to more clearly understand the technical means of the utility model, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the utility model more obvious and easy to understand, the specific implementation methods of the utility model are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] By reading the detailed description of the preferred embodiment below, various other advantages and benefits will become clear to those of ordinary skill in the art. The accompanying drawings are only used for the purpose of illustrating the preferred embodiment and are not considered to be limiting of the present invention. Moreover, the same reference symbols are used throughout the accompanying drawings to represent the same components. In the accompanying drawings:

[0019] Figure 1 Schematic diagram of the connection between the head cover and the top of the suit for the macaque transcutaneous electrical acupoint stimulation experiment of the utility model Figure 1 ;

[0020] Figure 2 Schematic diagram of the connection between the head cover and the top of the suit for the macaque transcutaneous electrical acupoint stimulation experiment of the utility model Figure 2 ;

[0021] Figure 3 This is a schematic diagram of a state in which the collar of the helmet of the suit for percutaneous electrical acupoint stimulation experiment of macaques of the present invention is opened;

[0022] Figure 4 It is a schematic diagram of the state of the helmet of the suit for transcutaneous electrical acupoint stimulation experiment of macaques of the present invention after being worn;

[0023] Figure 5 A stereoscopic diagram of the stimulation electrodes of the suit for the macaque transcutaneous electrical acupoint stimulation experiment of the present utility model;

[0024] Figure 6A three-dimensional diagram of the stimulation electrode of the suit for macaque transcutaneous electrical acupoint stimulation experiment of the utility model with the electrode cover removed;

[0025] Figure 7 The utility model is an exploded view of the stimulation electrode of the suit for macaque transcutaneous electrical acupoint stimulation experiment. DETAILED DESCRIPTION

[0026] In order to better understand the purpose, function and specific design of the utility model, the utility model is described in further detail below with reference to the accompanying drawings.

[0027] like Figure 1-7 As shown, the suit for percutaneous electrical acupoint stimulation experiment of macaques of the utility model comprises a top 1, an acupuncture instrument 2, a head cover 5 and a helmet 6. The acupuncture instrument 2 is fixedly arranged on the outer side of the back of the top 1, and the acupuncture instrument 2 is connected with a stimulation electrode 3 and a detection electrode 4, which are fixed on the head cover 5, and the head cover 5 is fitted on the head of the macaque, and the stimulation electrode 3 can stimulate the acupoints on the head of the macaque. In this embodiment, there are two stimulation electrodes 3, which are respectively arranged at the Baihui acupoint on the top of the head and the Yintang acupoint between the eyebrows; the detection electrode 4 is arranged on the forehead or behind the ear of the macaque to detect brain wave signals; the helmet 6 can be mounted on the outside of the head cover 5 and snapped with the neck of the macaque to prevent the macaque from scratching the stimulation electrode 3 and the detection electrode 4; the acupuncture instrument 2 is connected to a power supply component, which can provide current for the stimulation electrode 3 and the detection electrode 4, and the power supply component is a battery or a power supply; the acupuncture instrument 2 is connected to a wireless communication module, through which the acupuncture instrument 2 can be remotely controlled and the changes in brain waves can be remotely received and recorded in real time. The wireless communication module can be an existing Wifi module or a Bluetooth module or other module that can transmit data wirelessly.

[0028] Specifically, if Figure 1-4 As shown, the top 1 is a sleeveless short top, and the left and right sides of the front are connected by a zipper. Its specific structure can adopt the existing zipper top structure, which will not be repeated here. A stand-up collar 11 is provided at the neckline of the top 1, and the stand-up collar 11 can fit the monkey's neck. The stimulation electrode 3 and the detection electrode 4 are connected to the acupuncture instrument 2 through a wire, and the wire passes through the back of the top 1 and is connected to the acupuncture instrument 2, so that the wire is routed on the inside of the top 1 to prevent the macaque from pulling the wire.

[0029] Preferably, in order to make the head cover 5 fit the macaque's head better, the head cover 5 of this embodiment is a 3D printed one-piece structure with reference to the macaque's head shape, and then through holes are opened at the ears and eyes, so that the ears and eyes of the macaque can be used normally, reducing the macaque's anxiety. In addition, holes are opened at the top of the head, the center of the eyebrows, the forehead, etc., where stimulation or detection is required, and then the stimulation electrode 3 or the detection electrode 4 is fixed to the corresponding position, and the fixing method can be adhesive. A strap 51 is also provided below the head cover 5 of this embodiment, and the strap 51 can be snapped with the macaque's lower jaw to make the head cover 5 more firmly fixed.

[0030] like Figure 3-4 As shown, a collar 61 that can be opened and closed is provided below the helmet 6, and the collar 61 can be worn in the open state. After the macaque wears the helmet 6, the collar 61 is closed and locked, and the collar 61 is clamped with the macaque's neck to complete the fixing of the helmet 6. An elastic collar 611 is fixedly provided inside the collar 61, and the elastic collar 611 can contact with the macaque's neck to provide support for the helmet 6. The material of the elastic collar 611 can be made of sponge or silica gel, so that the elastic collar 611 is softer, making the macaque more comfortable after wearing. The collar 61 includes a semi-circular fixed portion 612 and a movable portion 613, the fixed portion 612 is fixedly connected to the bottom of the helmet 6, one end of the movable portion 613 is hinged with the fixed portion 612, and the other end of the movable portion 613 is detachably connected with the fixed portion 612, and the opening and closing of the collar 61 is realized by rotating the movable portion 613.

[0031] In this embodiment, a connecting plate 614 is respectively provided at one end of the movable part 613 and the fixed part 612 which are detachably connected to each other. The connecting plates 614 on the movable part 613 and the fixed part 612 can contact each other. Both connecting plates 614 are provided with connecting holes. The two connecting plates 614 can be connected by bolts to lock the movable part 613 and the fixed part 612.

[0032] The helmet 6 is made of a transparent material to facilitate observation of the state of the macaque and the wearing of the stimulation electrode 3 and the detection electrode 4 on the headgear 5. An eyepiece 62 is provided at the position corresponding to the macaque's face on the front side of the helmet 6. The eyepiece 62 is provided with a VR display screen. The eyepiece 62 can play videos of interest to the macaque to attract the macaque's attention, reduce the boredom during the experiment, and make the experimental results more accurate. Preferably, the helmet 6 is also provided with a Bluetooth headset 63 at the position corresponding to the macaque's ear to increase the functions of noise reduction and music playback. Music can be played or breathing guidance can be performed during the experiment to improve the comfort of the experimental process.

[0033] like Figure 5-7As shown, the stimulation electrode 3 includes an electrode seat 31, and the electrode seat 31 includes a receiving cavity 311. An electrode head 32 is arranged at the center of the receiving cavity 311. The electrode head 32 is connected to a wire, and the wire extends to the outside of the electrode seat 31 and is connected to the acupuncture instrument 2. A fixing component 33 is sleeved on the outside of the electrode head 32, and the fixing component 33 is accommodated in the receiving cavity 311. The fixing component 33 can fix the electrode head 32 on the skin surface to prevent the electrode head 32 from moving. The fixing component 33 includes an adhesive ring 331, and the adhesive ring 331 is detachably arranged in an annular fixing groove 332. The height of the upper surface of the adhesive ring 331 is lower than the height of the electrode head 32, that is, the electrode head 32 protrudes from the upper surface of the adhesive ring 331 to ensure reliable contact between the electrode head 32 and the skin. The inner ring of the annular fixing groove 332 is sleeved with the electrode head 32, and the outer ring of the annular fixing groove 332 is interference fit with the receiving cavity 311 of the electrode seat 31.

[0034] Preferably, in order to facilitate the replacement of the adhesive ring 331, a plurality of first through holes 333 are provided at the bottom of the fixing groove 332. By pressing the adhesive ring 331 through the first through holes 333 with a tool, the adhesive ring 331 can be pushed out of the fixing groove 332. It is understandable that a plurality of second through holes can also be provided at positions corresponding to the bottom of the fixing groove 332 on the electrode holder 31 to facilitate the removal of the fixing groove 332. The adhesive ring 331 of this embodiment can be made of silicone gel, soft silicone dressing, self-adhesive polyurethane foam dressing, etc.; it can also be made by coating a composite hydrocolloid or acrylic adhesive on the upper surface of the adhesive ring 331 made of elastic material.

[0035] It is worth noting that the stimulation electrode 3 further includes an electrode cover 34, which is detachably connected to the outer surface of the electrode holder 31 or the fixing groove 332. In this embodiment, the electrode cover 34 is threadedly connected to the outer surface of the fixing groove 332. The electrode cover 34 can prevent the adhesive ring 331 from adhering to other objects or the top 11 when the stimulation electrode 3 is not in use.

[0036] In addition, the structures of the detection electrode 4 and the stimulation electrode 3 of this embodiment are the same, and will not be described in detail here.

[0037] When the utility model is used, the hair at the Baihui acupoint on the top of the macaque's head is first shaved off, and then the coat 1 is put on the macaque, and then the head cover 5 is set on the head of the macaque, and the head cover 5 is fixed with a strap 51, and then the zipper of the coat 1 is pulled to the top, so that the stand-up collar 11 fits the macaque's neck, and then the helmet 6 is put on, and the neck ring 61 is locked, and the wearing of the utility model is completed. It is worth noting that the zipper head can be hidden inside the neck ring 61 to prevent the macaque from pulling the zipper.

[0038] According to the experimental needs, the Baihui acupoint and the Yintang acupoint can be electrically stimulated at the same time, or they can be stimulated separately, that is, the Baihui acupoint can be stimulated first and then the Yintang acupoint, or the Yintang acupoint can be stimulated first and then the Baihui acupoint, or the Baihui acupoint and the Yintang acupoint can be stimulated at the same time; in addition, according to the experimental needs, the ear acupoints can also be stimulated. The detection electrode 4 detects the brain electrical signal while electrically stimulating and transmits it to the computer for recording and analyzing the brain electrical signal. The acupuncture instrument 2 can use the Huatuo brand SDZ-II type electronic acupuncture instrument.

[0039] The utility model is a suit for macaque transcutaneous electrical acupoint stimulation experiments, which is cleverly designed and easy to operate. It adopts a combination of a top 1, a head cover 5 and a helmet 6, and the electrode wires are routed inside the helmet 6 and the top 1, which prevents the macaque from pulling off the stimulation electrode 3 and the detection electrode 4 during the experiment, thereby ensuring the reliability of the experiment. By providing an openable and closable neck ring 61, on the one hand, the convenience of wearing the helmet 6 is improved, and on the other hand, the zipper head can be hidden in the neck ring 61 to prevent the macaque from pulling the zipper. In addition, an elastic ring 611 is provided in the neck ring 61, which improves the comfort of the macaque in wearing. Finally, the sticky fixing components on the stimulation electrode 3 and the detection electrode 4 can further fix the electrodes, which greatly improves the reliability of the electrode work and the effectiveness of electrical stimulation. At the same time, since the elastic sticky ring is in contact with the skin, the squeezing feeling of the electrode head is reduced, thereby increasing the comfort.

[0040] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the utility model.

Claims

1. A suit for a rhesus monkey transcutaneous electrical acupoint stimulation experiment, characterized in that: The invention comprises a top, an acupuncture therapy instrument, a head cover and a helmet. An acupuncture therapy instrument is fixedly arranged on the outer side of the back of the top. Stimulation electrodes and detection electrodes are connected to the acupuncture therapy instrument. The stimulation electrodes and detection electrodes are fixed on the head cover. The head cover is snugly mounted on the head of the macaque. The stimulation electrodes can stimulate the acupuncture points on the head of the macaque, and the detection electrodes can detect brain wave signals. The helmet can be mounted on the outside of the head cover and snapped into the neck of the macaque. The acupuncture therapy instrument is connected to a power supply component, which can provide current for the stimulation electrodes and the detection electrodes. The acupuncture therapy instrument is connected to a wireless communication module, through which the acupuncture therapy instrument can be remotely controlled and changes in brain waves can be remotely received and recorded in real time.

2. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 1, characterized in that: The stimulation electrode and the detection electrode are connected to the acupuncture therapy device through a wire, the wire passes through the back of the top and is connected to the acupuncture therapy device, and the wire is arranged on the inner side of the top.

3. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 1, characterized in that: The hood is a 3D printed one-piece structure.

4. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 3, characterized in that: A strap is also provided under the hood, and the strap can be snapped into the lower jaw of the macaque.

5. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 1, characterized in that: An openable and closable neck ring is arranged under the helmet, and an elastic ring is fixedly arranged on the inner side of the neck ring, and the elastic ring can contact with the neck of the macaque.

6. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 5, characterized in that: The neck ring includes a semi-circular fixed part and a movable part. The fixed part is fixedly connected to the bottom of the helmet, one end of the movable part is hinged to the fixed part, and the other end of the movable part is detachably connected to the fixed part. The opening and closing of the neck ring is achieved by rotating the movable part.

7. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 6, characterized in that: An eyepiece is provided on the front side of the helmet at a position corresponding to the face of the macaque, and a VR display screen is provided on the eyepiece.

8. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 7, characterized in that: The helmet is also equipped with a Bluetooth headset at the position corresponding to the macaque's ears to increase the functions of noise reduction and music playback.

9. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 1, characterized in that: There are two stimulating electrodes, which are respectively set at the Baihui point on the top of the head and the Yintang point between the eyebrows.

10. The suit for percutaneous electrical acupoint stimulation experiment of macaques as claimed in claim 1, characterized in that: The detection electrodes are placed on the forehead or behind the ears of the macaques.

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