Filtering equipment for synthesis and preparation of medical intermediates

Abstract

The utility model relates to the technical field of medical intermediate preparation, and discloses medical intermediate synthesis preparation filtering equipment which comprises a supporting plate, a plurality of containing holes are formed in the top end of the supporting plate, connecting columns are connected into the containing holes in a sliding mode, and a filtering tank is fixedly connected to the top ends of the connecting columns. The device comprises a supporting plate, the top end of the supporting plate is fixedly connected with an isolation assembly used for isolating a filtering tank, the interior of the supporting plate is in threaded connection with threaded rods, the far sides of the multiple threaded rods are fixedly connected with rotating discs, and the close sides of the exteriors of the multiple threaded rods are rotationally connected with limiting plates. And one limiting plate is fixedly connected with two telescopic rods. According to the filter tank disclosed by the utility model, the filter tank can be taken down from the supporting plate, so that cleaning personnel can clean the filter tank more conveniently, the time required for cleaning is reduced, the overall downtime is further reduced, and the continuity and efficiency of production are ensured.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical intermediate preparation, in particular to a synthetic preparation filtering device for pharmaceutical intermediates. Background Art

[0002] A pharmaceutical intermediate refers to a semi-finished product obtained during the drug synthesis process. These intermediates need to be converted into final drug products in subsequent steps. During the drug synthesis process, various impurities will be mixed into the intermediates. The use of synthetic preparation filtration equipment can effectively remove these impurities, improve the purity of the intermediates, and lay the foundation for the quality of the final product.

[0003] In the prior art, some synthetic preparation filtering equipment usually uses a filter screen inside a filter tank to filter the drugs. However, after a long period of filtration, the filtered impurities will remain inside the filter barrel and accumulate, which will clog the filter screen or affect the filtering effect of the filter material. At this time, the filter tank needs to be cleaned, but most of the filter tanks are fixed on the support plate by welding, which greatly increases the difficulty of cleaning the inside of the filter tank, reduces the cleaning efficiency, and then increases the overall downtime. Therefore, in view of the above shortcomings, a synthetic preparation filtering equipment for pharmaceutical intermediates is proposed. Utility Model Content

[0004] The purpose of the utility model is to solve the shortcomings existing in the prior art, and to propose a synthetic preparation filtering device for pharmaceutical intermediates, aiming to improve the problem in the prior art that it is difficult to clean the inside of the filter tank, which will reduce the cleaning efficiency and then increase the overall downtime.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a synthetic preparation and filtering equipment for pharmaceutical intermediates, comprising a support plate, a plurality of accommodating holes are opened at the top of the support plate, a connecting column is slidably connected inside the accommodating hole, a filter tank is fixedly connected to the top of the connecting column, an isolation component for isolating the filter tank is fixedly connected to the top of the support plate, a threaded rod is internally threadedly connected to the support plate, a rotating disk is fixedly connected to the far sides of the plurality of threaded rods, a limiting plate is rotatably connected to the outer sides of the plurality of threaded rods, one of the limiting plates is fixedly connected to two telescopic rods, a strong spring is sleeved on the outer side of the telescopic rod, and a clamping block is movably connected to the outer side of one side of the threaded rod.

[0006] Furthermore, a sealing cover is detachably connected to the top of the filter tank, and two connecting pipes are fixedly connected to the top of the sealing cover, wherein three connecting sleeves are sleeved on the outside of six connecting pipes, and an inlet sleeve and a discharge sleeve are respectively sleeved on the outside of the other two connecting pipes, and a collecting box is fixedly connected to one side of the support plate, and a centrifugal pump is fixedly connected to the top of the collecting box.

[0007] Furthermore, the isolation assembly includes a partition, and the bottom end of the partition is fixedly connected to the top end of the support plate.

[0008] Furthermore, the top end of the support plate is in contact with the bottom end of the filter tank, and one side of the telescopic rod is fixedly connected to one side of the clamping block.

[0009] Furthermore, a plurality of chambers are opened inside the support plate, the outside of the limit plate is slidably connected to the inside of the chamber, and the outside of the clamping block is slidably connected to the inside of the chamber.

[0010] Furthermore, one end of the strong spring is fixedly connected to one side of the limit plate, and the other end of the strong spring is fixedly connected to one side of the clamping block.

[0011] Further, one side of the clamping block contacts the outside of the filter tank, and one side of the rotating disk contacts one side of the supporting plate.

[0012] Furthermore, the top end of the centrifugal pump is fixedly connected to the bottom end of the discharge sleeve.

[0013] The utility model has the following beneficial effects:

[0014] 1. In the utility model, the locking force of the clamping block on the connecting column is eliminated by rotating the rotating disk to drive the threaded rod, so that the filter tank can be removed from the supporting plate, making it more convenient for cleaning personnel to clean the filter tank, reducing the time required for cleaning, and then reducing the overall downtime, ensuring the continuity and efficiency of production.

[0015] 2. In the utility model, by connecting the connecting sleeve, the feeding sleeve, and the discharging sleeve with the connecting pipe, the drug solution can be filtered multiple times, which can effectively remove insoluble matter and suspended particles generated during the synthesis process, ensure the purity and cleanliness of the drug, and reduce the rework rate caused by impurity problems, thereby improving production efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 A three-dimensional diagram of a synthetic preparation and filtering device for a pharmaceutical intermediate proposed in the utility model;

[0017] Figure 2This is a schematic diagram of the connecting column structure of a synthetic preparation filtering device for a pharmaceutical intermediate proposed in the utility model;

[0018] Figure 3 This is a schematic diagram of the support plate structure of a synthetic preparation filtering device for pharmaceutical intermediates proposed in the utility model;

[0019] Figure 4 The utility model provides a schematic diagram of the connecting sleeve structure of a synthetic preparation filtering device for pharmaceutical intermediates.

[0020] Legend:

[0021] 1. Support plate; 2. Partition plate; 3. Filter tank; 4. Connecting column; 5. Receiving hole; 6. Threaded rod; 7. Rotating disk; 8. Limiting plate; 9. Telescopic rod; 10. Power spring; 11. Clamping block; 12. Chamber; 13. Sealing cover; 14. Connecting pipe; 15. Connecting sleeve; 16. Inlet sleeve; 17. Outlet sleeve; 18. Collecting box; 19. Centrifugal pump. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] Reference Figure 1 - Figure 3, an embodiment provided by the utility model: a synthetic preparation filtering device for pharmaceutical intermediates, including a main supporting structure of a support plate 1, a plurality of accommodating holes 5 are opened at the top of the support plate 1 for installing subsequent components, a connecting column 4 is slidably connected inside the accommodating hole 5 to play a supporting and connecting role, a filter tank 3 is fixedly connected to the top of the connecting column 4, and a plurality of filter tanks 3 are stacked and connected for multi-stage filtering treatment, the top of the support plate 1 is in contact with the bottom end of the filter tank 3, and an isolation assembly for isolating the filter tank 3 is fixedly connected to the top of the support plate 1 for isolating the space between different filter tanks 3 to ensure clean and orderly operation, the isolation assembly includes a partition 2, the bottom end of the partition 2 is fixedly connected to the top of the support plate 1, a threaded rod 6 is threadedly connected to the inside of the support plate 1, and a plurality of threaded rods 6 are fixedly connected to a rotating disk 7 on the far side for the operator to rotate the threaded rod 6, one side of the rotating disk 7 is in contact with one side of the support plate 1, and a plurality of threaded rods 6 are fixedly connected to the far side. The outer side of the rod 6 is rotatably connected to the limit plate 8, and one of the limit plates 8 is fixedly connected to two telescopic rods 9. The outer part of the telescopic rod 9 is sleeved with a strong spring 10, and the outer side of one side of the threaded rod 6 is movably connected to a clamping block 11, which controls the movement of the clamping block 11 by rotation, thereby realizing the disassembly and fixation of the filter tank 3. One end of the strong spring 10 is fixedly connected to one side of the limit plate 8, and the other end of the strong spring 10 is fixedly connected to one side of the clamping block 11. One side of the clamping block 11 contacts the outside of the filter tank 3, and one side of the telescopic rod 9 is fixedly connected to one side of the clamping block 11 to provide sufficient pressure and support to ensure the stability and reliability of the clamping block 11. A plurality of chambers 12 are opened inside the support plate 1, and the outer part of the limit plate 8 is slidably connected to the inside of the chamber 12, and the outer part of the clamping block 11 is slidably connected to the inside of the chamber 12 to clamp and fix the filter tank 3, so that it can be disassembled and replaced when necessary.

[0024] Reference Figure 1 , Figure 2 and Figure 4 The top of the filter tank 3 is detachably connected to a sealing cover 13, and the top of the sealing cover 13 is fixedly connected to two connecting pipes 14 for feeding, discharging and other operations, among which six connecting pipes 14 are externally sleeved with three connecting sleeves 15, and the other two connecting pipes 14 are externally sleeved with a feeding sleeve 16 and a discharging sleeve 17 respectively. These sleeves are used to transport and receive chemicals or solutions and support the fluid operation and processing functions of the equipment. One side of the support plate 1 is fixedly connected to a collecting box 18 for collecting products treated by the filter tank, and the top of the collecting box 18 is fixedly connected to a centrifugal pump 19, and the top of the centrifugal pump 19 is fixedly connected to the bottom end of the discharging sleeve 17 to output the treated liquid or solution to the next processing stage or storage facility through the discharging sleeve 17.

[0025] Working principle: First, the filtered liquid medicine needs to be introduced into the first filter tank 3 from the feed sleeve 16 through the action of the centrifugal pump 19, and then connected to the connecting column 4 at the top of the two filter tanks 3 through the connecting sleeve 15, so that the introduced liquid medicine is introduced from the first barrel through the connecting sleeve 15 to the second barrel for secondary filtration, and so on, until the last barrel is filtered and the liquid medicine that has been filtered for multiple times is collected from the discharge sleeve 17 through the centrifugal pump 19 to the inside of the collection box 18, and then when the filter tank 3 needs to be dismantled and cleaned, the staff will twist the rotating disk 7. When the rotating disk 7 is twisted, the threaded rod 6 will be driven to move inside the support plate 1, and then the movement of the threaded rod 6 will drive the limit plate 8 to slide inside the chamber 12, and then the sliding of the limit plate 8 will drive the telescopic rod 9 and the strong spring 10 to move, and then drive the clamping force of the clamping block 11 on the connecting column 4 to disappear, so that the filter tank 3 can be better disassembled and removed, and the threaded rod 6 and the clamping block 11 are movably connected, and the movable space 1 is large, so that the strong spring 10 can adaptively adjust the clamping block 11, in order to achieve a better effect when locking the filter tank 3.

[0026] Finally, it should be noted that the above are only preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A synthetic preparation filtering device for pharmaceutical intermediates, comprising a support plate, characterized in that: The top of the support plate is provided with a plurality of accommodating holes, the inside of the accommodating holes is slidably connected with a connecting column, the top of the connecting column is fixedly connected with a filter tank, the top of the support plate is fixedly connected with an isolation component for isolating the filter tank, the internal thread connection of the support plate is connected with a threaded rod, the far sides of the plurality of threaded rods are fixedly connected with a rotating disk, the outer sides of the plurality of threaded rods are rotatably connected with a limiting plate, one of the limiting plates is fixedly connected with two telescopic rods, the outer side of the telescopic rod is sleeved with a strong spring, and one side of the threaded rod is movably connected with a clamping block.

2. The synthetic preparation and filtering equipment for pharmaceutical intermediates according to claim 1, characterized in that: The top of the filter tank is detachably connected to a sealing cover, and the top of the sealing cover is fixedly connected to two connecting pipes, among which six connecting pipes are externally sleeved with three connecting sleeves, and the other two connecting pipes are externally sleeved with a feed sleeve and a discharge sleeve respectively, one side of the support plate is fixedly connected to a collecting box, and the top of the collecting box is fixedly connected to a centrifugal pump.

3. The synthetic preparation and filtering equipment for pharmaceutical intermediates according to claim 1, characterized in that: The isolation assembly comprises a partition plate, the bottom end of which is fixedly connected to the top end of the support plate.

4. The synthetic preparation and filtration equipment for pharmaceutical intermediates according to claim 1, characterized in that: The top end of the support plate contacts the bottom end of the filter tank, and one side of the telescopic rod is fixedly connected to one side of the clamping block.

5. The synthetic preparation and filtration equipment for pharmaceutical intermediates according to claim 1, characterized in that: A plurality of chambers are provided inside the support plate, the outside of the limit plate is slidably connected to the inside of the chamber, and the outside of the clamping block is slidably connected to the inside of the chamber.

6. The synthetic preparation and filtration equipment for pharmaceutical intermediates according to claim 1, characterized in that: One end of the strong spring is fixedly connected to one side of the limit plate, and the other end of the strong spring is fixedly connected to one side of the clamping block.

7. The synthetic preparation and filtration equipment for pharmaceutical intermediates according to claim 1, characterized in that: One side of the clamping block contacts the outside of the filter tank, and one side of the rotating disk contacts one side of the supporting plate.

8. The synthetic preparation and filtration equipment for pharmaceutical intermediates according to claim 2, characterized in that: The top end of the centrifugal pump is fixedly connected to the bottom end of the discharge sleeve.

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