Dialysis membrane activating and cleaning device and system

Abstract

The utility model provides a dialysis membrane activating and cleaning device and system, and belongs to the field of experimental equipment. The device comprises a liquid storage tank for storing a buffer solution and / or a reaction solution, a reaction tank, a first pipeline, a second pipeline, a third pipeline, a peristaltic pump, a sensor and a controller, the first pipeline is respectively connected with the liquid storage tank and the peristaltic pump, the second pipeline is respectively connected with the peristaltic pump and the reaction tank, the reaction tank is provided with a containing cavity, a porous sieve plate located in the middle of the containing cavity and an outlet located in the bottom of the containing cavity, the third pipeline is connected with the outlet of the reaction tank, and the second pipeline is connected with the liquid storage tank. The sensor is arranged close to the reaction tank, and the controller is electrically connected with the peristaltic pump and the sensor respectively.

Description

Technical Field

[0001] The present disclosure relates to the field of experimental equipment, and in particular to a dialysis membrane activation and cleaning device and system. Background Art

[0002] The dialysis membrane needs to be cleaned before use or during reuse. The current cleaning methods are mostly done manually and are inefficient. Utility Model Content

[0003] The embodiment of the present disclosure provides a dialysis membrane activation and cleaning device and system. The technical solution is as follows:

[0004] The present disclosure provides a dialysis membrane activation and cleaning device, the device comprising:

[0005] A liquid storage tank for storing buffer and / or reaction liquid, a reaction tank, a first pipeline, a second pipeline, a third pipeline, a peristaltic pump, a sensor and a controller;

[0006] The first pipeline is connected to the liquid storage tank and the peristaltic pump respectively, the second pipeline is connected to the peristaltic pump and the reaction tank respectively, the reaction tank has a containing chamber, a porous sieve plate located in the middle of the containing chamber and an outlet located at the bottom of the containing chamber, the third pipeline is connected to the outlet of the reaction tank, the sensor is arranged close to the reaction tank, and the controller is electrically connected to the peristaltic pump and the sensor respectively.

[0007] Optionally, the liquid storage tank includes a plurality of liquid storage tanks;

[0008] The first pipeline includes a plurality of first branches, each of which is provided with a control valve, the plurality of liquid storage tanks are respectively connected to the peristaltic pump via the plurality of first branches, and the control valve is electrically connected to the controller.

[0009] Optionally, the device further comprises: H 2 O pipeline, the H 2 The O pipeline is provided with a control valve, and the H 2 The O pipe is connected to the first pipe.

[0010] Optionally, the sensor includes a liquid level sensor and a three-way sensor;

[0011] The liquid level sensor is arranged on the side wall of the reaction tank, and the three-way sensor is connected to the outlet of the reaction tank and the third pipeline respectively.

[0012] Optionally, the device further comprises: a liquid level sensor driving chip and a three-way sensor driving chip;

[0013] The liquid level sensor is electrically connected to the controller via the liquid level sensor driving chip, and the three-way sensor is electrically connected to the controller via the three-way sensor driving chip.

[0014] Optionally, the device further comprises: a waste liquid pump and a waste liquid valve;

[0015] The waste liquid valve is located on the third pipeline, the waste liquid pump is connected to the third pipeline, and the controller is electrically connected to the waste liquid valve and the waste liquid pump respectively.

[0016] Optionally, the device further comprises: an air pump;

[0017] The air pump is connected to the third pipeline, and the controller is electrically connected to the controller.

[0018] Optionally, the device further comprises: a wireless communication module, wherein the wireless communication module is electrically connected to the air pump.

[0019] Optionally, the wireless communication module is a Bluetooth module.

[0020] The disclosed embodiment also provides a dialysis membrane activation and cleaning system, which includes the device as described above and a mobile terminal wirelessly connected to the device.

[0021] The technical solution provided by the embodiments of the present disclosure has the following beneficial effects:

[0022] In the dialysis membrane activation and cleaning device provided in the embodiment of the present disclosure, a liquid storage tank for storing buffer solution and / or reaction solution is provided, and is connected to the reaction tank through a pipeline and a peristaltic pump. The reaction tank has a holding cavity, a porous sieve plate is provided in the middle of the holding cavity, and an outlet is provided at the bottom. When the dialysis membrane is activated or cleaned, the controller controls the peristaltic pump to operate, pumping the solution in the liquid storage tank into the reaction tank to activate or clean the dialysis membrane on the porous sieve plate. At the same time, the controller can also feedback the state of the dialysis membrane during the cleaning process through the sensor, so as to control the peristaltic pump in real time, thereby realizing the automation of dialysis membrane activation and cleaning, saving manpower and improving efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions in the embodiments of the present disclosure, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present disclosure. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0024] Figure 1 is a connection diagram of a dialysis membrane activation and cleaning device provided in an embodiment of the present disclosure;

[0025] Figure 2 is a schematic structural diagram of a dialysis membrane activation and cleaning device provided in an embodiment of the present disclosure;

[0026] Figure 3 It is a structural schematic diagram of a dialysis membrane activation and cleaning system provided in an embodiment of the present disclosure. DETAILED DESCRIPTION

[0027] In order to make the objectives, technical solutions and advantages of the present disclosure more clear, the embodiments of the present disclosure will be further described in detail below with reference to the accompanying drawings.

[0028] Figure 1 Schematic diagram of the connection of a dialysis membrane activation and cleaning device provided by an embodiment of the present disclosure. Figure 1 The device includes: a liquid storage tank 101 for storing buffer and / or reaction liquid, a reaction tank 102, a first pipeline 103, a second pipeline 104, a third pipeline 105, a peristaltic pump 106, a sensor 107 and a controller 108.

[0029] The first pipeline 103 is connected to the liquid storage tank 101 and the peristaltic pump 106 respectively, the second pipeline 104 is connected to the peristaltic pump 106 and the reaction tank 102 respectively, the reaction tank 102 has a accommodating chamber, a porous sieve plate 1021 located in the middle of the accommodating chamber and an outlet located at the bottom of the accommodating chamber, the third pipeline 105 is connected to the outlet of the reaction tank 102, the sensor 107 is arranged close to the reaction tank 102, and the controller 108 is electrically connected to the peristaltic pump 106 and the sensor 107 respectively.

[0030] It should be noted that Figure 1 Except for the dotted line in 102 representing the porous sieve plate 1021, the other dotted lines represent electrical connections.

[0031] In the dialysis membrane activation and cleaning device provided in the embodiment of the present disclosure, a liquid storage tank for storing buffer solution and / or reaction solution is provided, and is connected to the reaction tank through a pipeline and a peristaltic pump. The reaction tank has a holding cavity, a porous sieve plate is provided in the middle of the holding cavity, and an outlet is provided at the bottom. When the dialysis membrane is activated or cleaned, the controller controls the peristaltic pump to operate, pumping the solution in the liquid storage tank into the reaction tank to activate or clean the dialysis membrane on the porous sieve plate. At the same time, the controller can also feedback the state of the dialysis membrane during the cleaning process through the sensor, so as to control the peristaltic pump in real time, thereby realizing the automation of dialysis membrane activation and cleaning, saving manpower and improving efficiency.

[0032] In the embodiment of the present disclosure, the controller 108 may be a processor, a programmable controller, a single-chip microcomputer or other devices.

[0033] The controller 108 executes the above control functions as conventional software algorithm functions, which will not be elaborated in the embodiment of the present disclosure.

[0034] See again Figure 1 The liquid storage tank 101 may include a plurality of liquid storage tanks 1011 .

[0035] The first pipeline 103 includes a plurality of first branches, each of which is provided with a control valve 1012 . The plurality of liquid storage tanks 1011 are respectively connected to the peristaltic pump 106 through the plurality of first branches, and the control valve 1012 is electrically connected to the controller 108 .

[0036] In the disclosed embodiment, the dialysis membrane activation and cleaning device can be applied in a variety of scenarios. The solutions used in different scenarios may be different. Therefore, multiple liquid storage tanks 1011 are provided to store different solutions, and the solution used is controlled by providing a control valve 1012, so that the device can be applied in different scenarios, thereby improving the practicality of the device. In addition, this structure can also mix different solutions in a certain proportion, and then activate or clean the dialysis membrane.

[0037] Exemplarily, the liquid storage pool 101 may include A, B, C, and D liquid storage tanks, which store 500 ml of high-concentration buffer / reaction solution, which is used for dialysis membrane activation and cleaning after real-time dilution.

[0038] In the embodiment of the present disclosure, each pipe (the first pipe, the second pipe and the third pipe) can be a polytetrafluoroethylene pipe.

[0039] For example, before the dialysis membrane is used, it needs to be activated and cleaned; if the dialysis membrane needs to be used repeatedly, the contents inside the membrane need to be cleaned for subsequent storage and reuse; after the membrane is used for dialysis of infectious, contaminating, or offensive objects, it needs to be rendered harmless before being discarded.

[0040] For example, using Na + Solution removes protective substances on the membrane; uses surfactants, or organic acids and bases for high-intensity cleaning; uses ethylenediaminetetraacetic acid (EDTA) to remove Cu 2+ and Hg 2+ And other heavy metal ions.

[0041] That is, the liquid storage tank 1011 can be used to store Na + Solutions, surfactants, organic detergents (such as alcohol, methanol), EDTA and other solutions.

[0042] In the embodiment of the present disclosure, the control valve 1012 may be an electromagnetically controlled one-way valve.

[0043] In the embodiment of the present disclosure, the peristaltic pump 106 may be a 12V DC motor peristaltic pump, which has a relatively fast flow rate, for example, 150 ml / min.

[0044] In the embodiment of the present disclosure, the reaction tank 102 may be a 50-200 ml reaction tank, for example, a 100 ml reaction tank.

[0045] The reaction tank 102 can be a high boron glass reaction tank, which has high transparency and is acid and alkali resistant. The reaction tank 102 is funnel-shaped, but the neck is short and frosted. The porous sieve plate in the middle is a glass sieve plate, which can prevent the dialysis membrane from being pumped away on the one hand, and can help the compressed air to form dense bubbles to improve the cleaning efficiency on the other hand.

[0046] See again Figure 1 The device may further include: H 2 O pipeline 109, the H 2 The O pipeline 109 is provided with a control valve 1012. 2 The O pipe 109 is connected to the first pipe 103 .

[0047] Among them, H 2 The O pipe 109 is connected to a water source, and can pass purified water / deionized water / double distilled water / tap water into the reaction tank for diluting the buffer solution / reaction solution, flushing the dialysis membrane, etc.

[0048] In this implementation, H 2 The O pipe 109 can pass water into the reaction tank to dilute the buffer solution / reaction solution, or to rinse the dialysis membrane to clean the reagents on the dialysis membrane.

[0049] In the embodiment of the present disclosure, the sensor 107 includes a liquid level sensor 1071 and a three-way sensor 1072 .

[0050] The liquid level sensor 1071 is arranged on the side wall of the reaction tank 102, and the three-way sensor 1072 is connected to the outlet of the reaction tank 102 and the third pipeline 105 respectively.

[0051] The liquid level sensor can be arranged on the side wall of the transparent reaction pool to detect the liquid level in the reaction pool 102. The three-way sensor 1072 is connected to the outlet of the reaction pool 102 to detect the ion concentration in the outlet solution, that is, the three-way sensor 1072 includes an ion concentration sensor.

[0052] In this implementation, the controller can control the flow rate based on the liquid level detected by the liquid level sensor, control the control valve and peristaltic pump, and adjust the liquid level to a suitable position. At the same time, the controller can also control the flow rate and switch based on the ion concentration detected by the three-way sensor, control the control valve and peristaltic pump, and control the progress of the activation and cleaning process.

[0053] Optionally, the device may further include a temperature control unit, which is arranged near the side wall of the reaction tank 102. The three-way sensor 1072 may also detect the temperature of the solution, that is, the three-way sensor 1072 includes a temperature sensor.

[0054] In this implementation, the controller can control the temperature control unit based on the solution temperature detected by the three-way sensor to adjust the solution to a suitable temperature.

[0055] See again Figure 1 The device may also include: a liquid level sensor driving chip 1073 and a three-way sensor driving chip 1074.

[0056] The liquid level sensor 1071 is electrically connected to the controller 108 via the liquid level sensor driver chip 1073 , and the three-way sensor 1072 is electrically connected to the controller 108 via the three-way sensor driver chip 1074 .

[0057] In this implementation, by providing the above-mentioned driver chip, it is ensured that the sensor detection data can be recognized by the controller, thereby ensuring the normal implementation of the control of the entire device.

[0058] See again Figure 1 The device may further include: a waste liquid pump 110 and a waste liquid valve 111.

[0059] The waste liquid valve 111 is located on the third pipeline 105 , the waste liquid pump 110 is connected to the third pipeline 105 , and the controller 108 is electrically connected to the waste liquid valve 111 and the waste liquid pump 110 , respectively.

[0060] In this implementation, by providing a waste liquid pump 110 and a waste liquid valve 111, waste liquid generated by the device can be collected to avoid pollution.

[0061] See again Figure 1 , the device may further include: an air pump 112.

[0062] The air pump 112 is connected to the third pipeline 105 , and the controller 108 is electrically connected to the air pump 112 .

[0063] In this implementation, when cleaning the dialysis membrane, it is also possible to use air instead of solution. At this time, no solution flows in the first pipe, the second pipe, and the third pipe, and each pipe passage is connected. At this time, the air pump works to drive the air flow to clean the dialysis membrane, which can remove dust or organic solvents on the membrane, or dehydrate the dialysis membrane for easy storage.

[0064] like Figure 1 As shown, the third pipeline 105 includes two branches, and the waste liquid pump 110 and the air pump 112 are connected to the two branches respectively.

[0065] See again Figure 1 The device may further include: a wireless communication module 113, wherein the wireless communication module 113 is electrically connected to the controller 108.

[0066] In this implementation, the wireless communication module is provided to enable wireless connection with a device outside the apparatus, thereby enabling wireless control of the apparatus by the external device.

[0067] In the embodiment of the present disclosure, the wireless communication module 113 may be a Bluetooth module, a WIFI module or other wireless communication modules.

[0068] Exemplarily, the wireless communication module 113 is a Bluetooth module, which has low cost and good compatibility.

[0069] Figure 2 Schematic diagram of the structure of a dialysis membrane activation and cleaning device provided in an embodiment of the present disclosure. Figure 2 As shown, the device can be integrated in a box 201, and the box 201 can integrate the aforementioned liquid storage tank 101, the first pipeline 103, the second pipeline 104 and the third pipeline 105 (not shown in the figure). The peristaltic pump 106, the control valve 1012, the waste valve 111, etc. can be arranged in the box 201. The waste pump 110, the air pump 112, the H 2 The inlet of O pipe 109 can be integrated on the side wall of box body 201.

[0070] The controller 108 and the wireless communication module 113 are also integrated on the side wall of the box 201, and a power switch 202 is provided for switch control.

[0071] The housing 202 is provided with a groove for arranging the reaction pool 102, and a liquid level sensor and a temperature control unit (not shown) can be arranged in the groove. The reaction pool 102 is detachably connected to the housing 202, so as to realize the placement and removal of the dialysis membrane.

[0072] Optionally, the device may also be provided with a plurality of reaction pools 102, which are detachably connected to the housing 202 to be connected to the pipeline. The reaction pools 102 may process a plurality of dialysis membranes in parallel to improve activation and cleaning efficiency.

[0073] Figure 3 is a structural block diagram of a dialysis membrane activation and cleaning system provided by an embodiment of the present disclosure. Figure 3 The system includes Figure 1 or Figure 2 The device 301 and the mobile terminal 302 wirelessly connected to the device 301 are shown.

[0074] In the dialysis membrane activation and cleaning system provided by the embodiment of the present disclosure, a liquid storage tank for storing buffer solution and / or reaction solution is provided, and is connected to the reaction tank through a pipeline and a peristaltic pump, and the reaction tank has a holding cavity, a porous sieve plate is provided in the middle of the holding cavity, and an outlet is provided at the bottom. When the dialysis membrane is activated or cleaned, the mobile terminal sends instructions to the controller, and the peristaltic pump is controlled by the controller to pump the solution in the liquid storage tank into the reaction tank to activate or clean the dialysis membrane on the porous sieve plate. At the same time, the controller can also feedback the state of the dialysis membrane during the cleaning process through the sensor, so as to control the peristaltic pump in real time, thereby realizing the automation of dialysis membrane activation and cleaning, saving manpower and improving efficiency.

[0075] In the embodiment of the present disclosure, the mobile terminal 302 may be a mobile phone, a tablet computer, a wearable device or the like.

[0076] The dialysis membrane activation and cleaning system provided in the embodiment of the present disclosure has a built-in simple single-chip microcomputer as the core of the control module. The single-chip microcomputer is connected to the Bluetooth module. The user can wirelessly connect to the device through a mobile phone application (app) and Bluetooth to set parameters such as the operating process, buffer / reaction solution dilution ratio, temperature, duration, etc.

[0077] When the dialysis membrane activation and cleaning system provided by the embodiment of the present disclosure is working:

[0078] (1) Place the dialysis membrane that needs to be activated or cleaned into the reaction tank.

[0079] (2) Insert the reaction pool into the channel and connect it to the pipeline of the box.

[0080] (3) Turn on the Bluetooth of your mobile phone, connect it to the controller, and send instructions via Bluetooth to make the controller work.

[0081] (4) The controller collects data based on instructions and sensors and controls the operation of various valves, pumps, temperature control units, etc.

[0082] The mobile terminal 302 and the controller 108 execute the above functions as conventional software algorithm functions, which will not be elaborated in the embodiment of the present disclosure.

[0083] The dialysis membrane activation and cleaning system provided by the disclosed embodiment can save manpower and improve flux. It can reduce the risk of operator burns and chemical exposure. It can save more reagents and provide better cleaning effects. It can monitor the cleaning effect in real time through sensors.

[0084] The above description is only an optional embodiment of the present disclosure and is not intended to limit the present disclosure. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present disclosure shall be included in the protection scope of the present disclosure.

Claims

1. A dialysis membrane activation and cleaning device, characterized in that: The device comprises: A liquid storage tank (101) for storing a buffer solution and / or a reaction solution, a reaction tank (102), a first pipeline (103), a second pipeline (104), a third pipeline (105), a peristaltic pump (106), a sensor (107) and a controller (108); The first pipeline (103) is connected to the liquid storage tank (101) and the peristaltic pump (106) respectively, the second pipeline (104) is connected to the peristaltic pump (106) and the reaction tank (102) respectively, the reaction tank (102) has a accommodating chamber, a porous sieve plate (1021) located in the middle of the accommodating chamber and an outlet located at the bottom of the accommodating chamber, the third pipeline (105) is connected to the outlet of the reaction tank (102), the sensor (107) is arranged close to the reaction tank (102), and the controller (108) is electrically connected to the peristaltic pump (106) and the sensor (107) respectively.

2. The device according to claim 1, characterized in that The liquid storage tank (101) comprises a plurality of liquid storage tanks (1011); The first pipeline (103) includes a plurality of first branches, each of which is provided with a control valve (1012); the plurality of liquid storage tanks (1011) are respectively connected to the peristaltic pump (106) via the plurality of first branches, and the control valve (1012) is electrically connected to the controller (108).

3. The device according to claim 2, characterized in that The device further comprises: an H2O pipeline (109), on which a control valve (1012) is provided, and the H2O pipeline (109) is connected to the first pipeline (103).

4. The device according to any one of claims 1 to 3, characterized in that The sensor (107) comprises a liquid level sensor (1071) and a three-way sensor (1072); The liquid level sensor (1071) is arranged on the side wall of the reaction tank (102), and the three-way sensor (1072) is respectively connected to the outlet of the reaction tank (102) and the third pipeline (105).

5. The device according to claim 4, characterized in that The device further comprises: a liquid level sensor driving chip (1073) and a three-way sensor driving chip (1074); The liquid level sensor (1071) is electrically connected to the controller (108) via the liquid level sensor driving chip (1073), and the three-way sensor (1072) is electrically connected to the controller (108) via the three-way sensor driving chip (1074).

6. The device according to any one of claims 1 to 3, characterized in that The device further comprises: a waste liquid pump (110) and a waste liquid valve (111); The waste liquid valve (111) is located on the third pipeline (105), the waste liquid pump (110) is connected to the third pipeline (105), and the controller (108) is electrically connected to the waste liquid valve (111) and the waste liquid pump (110), respectively.

7. The device according to claim 6, characterized in that The device further comprises: an air pump (112); The air pump (112) is connected to the third pipeline (105), and the controller (108) is electrically connected to the air pump (112).

8. The device according to any one of claims 1 to 3, characterized in that The device further comprises: a wireless communication module (113), wherein the wireless communication module (113) is electrically connected to the controller (108).

9. The device according to claim 8, characterized in that The wireless communication module (113) is a Bluetooth module.

10. A dialysis membrane activation and cleaning system, characterized in that: The system comprises the device according to any one of claims 1 to 9 and a mobile terminal wirelessly connected to the device.

Images