Simple single-cup uniform mixing mechanism
By designing a simple single cup mixing mechanism in a chemiluminescence immunoassay, the vortex mixing of the liquid is achieved by eccentric rotation and small amplitude shock, the problems of unsatisfactory mixing and poor structural stability in the prior art are solved, and more efficient liquid mixing and equipment compactness are achieved.
Patent Information
- Application Number
- CN202421534907.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-01
- Publication Date
- 2025-04-18
- Estimated Expiration
- 2034-07-01
AI Technical Summary
The mixing mechanism of existing chemiluminescence immunoassays has problems with poor results and poor structural stability, especially for low-throughput analyzers in small batches.
A simple single cup mixing mechanism is designed. By setting an eccentric rotation center line on the cup holder, and under the action of the constraint groove and guide column, the driving cup holder has both revolution and small oscillation, achieving vortex mixing of liquid.
It significantly improves the mixing effect of a single cup of liquid, ensures the consistent mixing degree of liquid in each reaction cup, and helps with stability detection results. At the same time, the mechanism is simple, compact, low-cost, saves stations, and is suitable for miniaturized design.
Smart Images

Figure CN222766296U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a chemiluminescent immunoassay analyzer, in particular to a simple single-cup mixing mechanism. Background Art
[0002] The chemiluminescence immunoassay analyzer is a medical testing instrument that performs immunoassay by testing serum. By combining the highly sensitive chemiluminescence assay technology with the highly specific immune response, it can be used for the detection and analysis of various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins and drugs.
[0003] The physical structure of the chemiluminescent immunoassay analyzer involves many modules such as filling, mixing, incubation, washing and detection. Among them, the mixing module is used to mix the liquid in the reaction cup. At present, mixing usually includes a driving mechanism and a support plate, on which multiple reaction cups can be placed, and the driving mechanism drives the support plate to rotate or drives the support plate to move up and down to achieve the purpose of mixing the liquid in the reaction cup. However, the mixing effects of these mixing methods are not ideal, and the structural design of shaking multiple reaction cups at the same time has the defects of poor structural stability and large space occupation, especially for small batches of low-throughput analyzers, the mixing mechanism needs to be further optimized. Utility Model Content
[0004] In view of this, the utility model provides a simple single-cup mixing mechanism, which can improve the mixing effect of a single cup of liquid and has the advantages of simple and compact structure.
[0005] To achieve the above purpose, the technical solution of the utility model is as follows:
[0006] A simple single cup mixing mechanism comprises a base plate, a rotating seat rotatably mounted on the base plate, and a driving assembly for driving the rotating seat to rotate. The key points are: a cup seat is rotatably mounted on the rotating seat, a cup placement groove for placing a reaction cup is provided on the upper part of the cup seat, a guide column is fixed on the base plate, and a restraint groove is provided on one side of the lower part of the cup seat, and the restraint groove is movably sleeved on the guide column;
[0007] The rotation centerline of the cup seat is eccentrically arranged relative to the rotation centerline of the rotating seat. Under the restraining action of the restraining groove and the guide column, when the driving assembly drives the rotating seat to rotate, the cup seat has both orbital revolution and slight oscillation around the rotation axis.
[0008] With the above structure, the rotation centerline of the cup holder is eccentrically arranged relative to the rotation centerline of the rotating seat. During the process of the driving assembly driving the cup holder to move, under the restraining action of the restraining groove and the guide column, the cup holder has both an orbital motion around the rotation centerline of the rotating seat and a small oscillation along its rotation axis. This kind of movement can make the liquid in the reaction cup on the cup holder in a vortex state, so that the reaction cup on the cup placement groove mixes the sample and reagent inside it in a vortex manner.
[0009] Preferably, the driving assembly is a motor, and the output shaft of the motor is fixedly connected to the bottom of the rotating seat.
[0010] Preferably, the upper portion of the rotating seat has an auxiliary eccentric seat extending vertically upward, the center line of the auxiliary eccentric seat is eccentrically arranged relative to the output shaft of the motor, and the lower portion of the cup seat is rotatably sleeved on the auxiliary eccentric seat via a bearing.
[0011] As a preferred embodiment, the eccentricity of the auxiliary eccentric seat relative to the output shaft is 1 mm. The above structure has the advantages of good structural stability and high compactness.
[0012] Preferably, a retaining portion extending outward is provided on the side of the lower end of the cup holder, the restraining groove is provided at the outer end of the retaining portion, and the guide column is a pin installed on the base plate.
[0013] As a preferred embodiment, the restraining groove is through-connected from top to bottom, and the outer end of the restraining groove is open. The above structure is adopted to facilitate the installation of the guide column.
[0014] Preferably, the fixed sleeve at the bottom of the rotating seat is provided with a positioning code disk, one end of the positioning code disk is provided with a grating notch, and the substrate is provided with a sensor for identifying the grating notch. The above structure is adopted so that the mechanical gripper can accurately grasp the reaction cup on the cup holder.
[0015] Compared with the prior art, the beneficial effects of the utility model are:
[0016] The simple single-cup mixing mechanism provided by the utility model is adopted, and the rotation centerline of the cup seat is eccentrically arranged relative to the rotation centerline of the rotating seat. During the process of the driving component driving the cup seat to move, under the constraint of the constraint groove and the guide column, the cup seat has both an orbital motion around the rotation centerline of the rotating seat and a small oscillation along its rotation axis. This kind of movement can make the liquid in the reaction cup on the cup seat present a vortex state, so that the reaction cup on the cup placement groove mixes the sample and reagent inside it in a vortex manner, which can significantly improve the mixing effect. At the same time, the structural design of mixing a single reaction cup can better control the mixing state of the liquid in the reaction cup, thereby ensuring that the mixing degree and effect of the liquid in each reaction cup are consistent, which helps to ensure the stability of subsequent test results. In addition, the mixing mechanism has a simple structure and low cost, and it also saves workstations, which helps to realize the compact and miniaturized design of the analyzer. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is a structural schematic diagram of a simple single-cup mixing mechanism;
[0018] Figure 2 It is a cross-sectional view of a simple single-cup mixing mechanism;
[0019] Figure 3 is a schematic diagram of the structure of the cup holder 3;
[0020] Figure 4 It is a cross-sectional view of the cup holder 3 . DETAILED DESCRIPTION
[0021] The utility model is further described below in conjunction with embodiments and drawings.
[0022] like Figure 1 As shown, a simple single cup mixing mechanism includes a base plate 1, on which a driving assembly 5 and a rotatable rotating seat 2 are arranged, and the driving assembly 5 can drive the rotating seat 2 to rotate. A cup holder 3 is rotatably mounted on the rotating seat 2, and a cup placement groove 31 for placing a reaction cup a is arranged on the upper part of the cup holder 3. A guide column 4 is fixed on the base plate 1, and a restraining groove 3a is arranged on one side of the lower part of the cup holder 3, and the restraining groove 3a is movably sleeved on the guide column 4. Figure 2 It can be seen that the rotation centerline of the cup holder 3 is eccentrically arranged relative to the rotation centerline of the rotating seat 2. Under the restraining action of the restraining groove 3a and the guide column 4, when the driving assembly 5 drives the rotating seat 2 to rotate, the cup holder 3 has both revolution and small oscillation along its rotation axis.
[0023] Based on the above structural design, the rotation center line of the cup holder 3 is eccentrically arranged relative to the rotation center line of the rotating seat 2. During the movement of the cup holder 3 driven by the driving assembly 5, under the constraint of the constraint groove 3a and the guide column 4, the cup holder 3 has both revolution around the rotation center line of the rotating seat 2 and rotation along its rotation center line. Such a movement mode can make the liquid in the reaction cup on the cup holder 3 present a vortex state, so that the reaction cup on the cup placement groove 31 mixes the sample and reagent inside it in a vortex manner, which can significantly improve the mixing effect. The structural design of mixing a single reaction cup can better control the mixing state of the liquid in the reaction cup, thereby ensuring that the mixing degree and effect of the liquid in each reaction cup are consistent, which helps to ensure the stability of the subsequent test results. At the same time, the mixing mechanism is simple and compact in structure, low in cost, and also saves workstations, and is particularly suitable for small batches of low-throughput analyzers.
[0024] Reference Figure 4 In this embodiment, the bottom diameter of the cup placement groove 31 is larger than the upper part thereof, so that the lower part of the reaction cup can be suspended in the cup placement groove 31. Such a design helps to improve the stability of the installation of the reaction cup a.
[0025] like Figure 2 As shown, in this embodiment, the driving component 5 is a motor 51, and the output shaft 52 of the motor 51 passes upward through the base plate 1 and is fixedly connected to the bottom of the rotating seat 2. The motor 51 drives the output shaft 52 to rotate, thereby driving the rotating seat 2 to rotate.
[0026] Re-attend Figure 2 The upper part of the rotating seat 2 has an auxiliary eccentric seat 21 extending vertically upward, and the center line of the auxiliary eccentric seat 21 is eccentrically arranged relative to the center line of the output shaft 52. The lower part of the cup seat 3 is rotatably mounted on the auxiliary eccentric seat 21 through a bearing. The rotation of the lower part of the rotating seat 2 can drive the lower part of the cup seat 3 to have both a revolution motion along the rotation center line of the output shaft 52 and an oscillation along the rotation center line of the auxiliary eccentric seat 21.
[0027] In this embodiment, the eccentric distance of the auxiliary eccentric seat 21 relative to the output shaft 52 is 1 mm. Such a structural design has the advantages of good structural stability and high compactness, and it is easier to control the mixing state of the liquid in the reaction cup a.
[0028] Please refer to Figure 1 , 2 4, a retaining portion 32 extending outward is provided at the side of the lower end of the cup holder 3, and a restraining groove 3a is provided at the outer end of the retaining portion 32. In this embodiment, the guide column 4 is a pin installed on the substrate 1. With such a design, after the lower part of the cup holder 3 is restricted by the guide column 4, the motor 51 can be operated to drive the lower part of the cup holder 3 to eccentrically shake, thereby achieving the purpose of mixing.
[0029] In this embodiment, the upper end of the guide column 4 is in a state of active connection with the restraining groove 3a, so as to prevent the lower part of the cup holder 3 from being completely fixed, prevent the mechanism from being stuck, and thus ensure the reliability of mixing. In addition, arranging the guide column 4 and the holding part 32 at the lower end of the cup holder 3 can further increase the shaking of the upper part of the cup holder 3, so that the liquid in the reaction cup a is mixed more fully.
[0030] Re-attend Figure 3 The constraint groove 3a is through-through from top to bottom, and the outer end of the constraint groove 3a is open to facilitate the installation of the guide column 4.
[0031] like Figure 1 and 2 As shown, a positioning code disk 6 is fixedly sleeved at the lower part of the rotating seat 2, a grating notch 61 is provided at one end of the positioning code disk 6, and a sensor 7 capable of identifying the grating notch 61 is provided on the substrate 1. In the initial state, the cup placement groove 31 on the cup holder 3 is located directly below the mechanical gripper of the analyzer, and at this time, the grating notch 61 is located at a position that can be identified by the sensor 7. After the liquid in the reaction cup a is mixed, when the sensor 7 identifies the grating notch 61, the driving component 5 stops driving, so that the cup holder 3 can stay at the initial position, so that the mechanical gripper can accurately grasp the reaction cup a.
[0032] Finally, it should be noted that the above description is only a preferred embodiment of the present invention. Under the guidance of the present invention, ordinary technicians in this field can make a variety of similar expressions without violating the purpose and claims of the present invention, and such changes fall within the scope of protection of the present invention.
Claims
1. A simple single-cup mixing mechanism, comprising a base plate (1), a rotating seat (2) rotatably mounted on the base plate (1), and a driving assembly (5) for driving the rotating seat (2) to rotate, characterized in that: A cup holder (3) is rotatably mounted on the rotating seat (2), a cup placement groove (31) for placing a reaction cup is provided on the upper portion of the cup holder (3), a guide column (4) is fixedly provided on the base plate (1), a restraining groove (3a) is provided on one side of the lower portion of the cup holder (3), and the restraining groove (3a) is movably sleeved on the guide column (4); The rotation centerline of the cup seat (3) is eccentrically arranged relative to the rotation centerline of the rotating seat (2); under the restraining action of the restraining groove (3a) and the guide column (4), when the driving component (5) drives the rotating seat (2) to rotate, the cup seat (3) has both orbital revolution and slight oscillation around its own rotation axis.
2. The simplified single-cup mixing mechanism according to claim 1, characterized in that: The driving component (5) is a motor (51), and the output shaft (52) of the motor (51) is fixedly connected to the bottom of the rotating seat (2).
3. The simplified single-cup mixing mechanism according to claim 2, characterized in that: The upper portion of the rotating seat (2) is provided with an auxiliary eccentric seat (21) extending vertically upwards, the center line of the auxiliary eccentric seat (21) being eccentrically arranged relative to the output shaft (52) of the motor (51), and the lower portion of the cup seat (3) is rotatably mounted on the auxiliary eccentric seat (21) via a bearing.
4. The simplified single-cup mixing mechanism according to claim 3, characterized in that: The eccentricity of the auxiliary eccentric seat (21) relative to the output shaft (52) is 1 mm.
5. The simplified single-cup mixing mechanism according to claim 1, characterized in that: The lower side of the cup holder (3) is provided with a retaining portion (32) extending outward, the restraining groove (3a) is arranged at the outer end of the retaining portion (32), and the guide column (4) is a pin mounted on the base plate (1).
6. The simplified single-cup mixing mechanism according to claim 5, characterized in that: The restraining groove (3a) is connected vertically, and the outer end of the restraining groove (3a) is open.
7. The simplified single-cup mixing mechanism according to claim 1, characterized in that: A positioning code disc (6) is fixedly sleeved at the bottom of the rotating seat (2), a grating notch (61) is provided at one end of the positioning code disc (6), and a sensor (7) for identifying the grating notch (61) is provided on the substrate (1).