Nucleic acid detection reagent card

Abstract

The utility model relates to the technical field of reagent cards, and discloses a nucleic acid detection reagent card which comprises an upper shell and a lower shell, a first magnet is embedded at the edge of the lower end face of the upper shell, a second magnet is embedded at the edge of the upper end face of the lower shell, and the upper shell and the lower shell are fixed through magnetic attraction of the first magnet and the second magnet. According to the reagent card, the magnetic type rapid opening and closing design is adopted, rapid opening and closing are facilitated, the interior of the reagent card is easy to clean due to the detachable design, the reagent card can be recycled only by replacing the detection paper, the use cost is reduced, and the reagent card is suitable for popularization and application. According to the reagent card, a combined design is adopted, two times of detection can be carried out at the same time, the two times of detection may involve different detection indexes or methods, the detection accuracy is improved, and the detection paper is fixed through the arranged pressing assembly, so that the situation that detection operation is difficult to carry out due to deviation of the detection paper in the using process is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of reagent cards, and specifically to a nucleic acid detection reagent card. Background Art

[0002] The characteristic of viruses is that they are very small in shape. They cannot be seen under ordinary optical microscopes, and cannot be directly observed with the naked eye. However, each virus has its own unique gene sequence. By detecting the viral nucleic acid in the patient's body, it can be determined whether the virus exists in the patient's body. Most of the current viral nucleic acid detection reagent cards use fluorescent quantitative PCR methods. The detection principle is to use the unique gene sequence of the virus as the detection target, and through PCR amplification, the target DNA sequence we choose is increased exponentially. Each amplified DNA sequence can be combined with a fluorescent labeled probe we added in advance to generate a fluorescent signal. The more target genes are amplified, the stronger the accumulated fluorescent signal. In samples without viruses, since there is no target gene amplification, the fluorescence signal enhancement cannot be detected. Therefore, nucleic acid detection is actually to determine whether there is viral nucleic acid in the sample by detecting the accumulation of fluorescent signals.

[0003] After searching, the Chinese patent with announcement number: CN214142355U discloses a DNA / RNA nucleic acid detection reagent card, including a reagent card housing, the upper surface of the reagent card housing is fixedly connected with a handle, the lower surface of the reagent card housing is provided with an isolation film, the surface of the isolation film away from the reagent card housing is provided with a protective film, the upper surface of the protective film is fixedly connected with a sticker, and the rear inner wall of the reagent card housing is provided with detection paper. The utility model, by providing an anti-overflow groove and an adsorbent, achieves the purpose of adsorbing excessive samples squeezed out by a dropper, preventing the samples from leaking and contaminating the workbench and other samples. A sealing sticker is designed on the back of the DNA / RNA nucleic acid detection reagent card. After the test, each DNA / RNA nucleic acid reagent card is independently packaged to prevent cross infection. By designing the inclined top of the DNA / RNA nucleic acid reagent card, gaps are left between the DNA / RNA nucleic acid reagent cards, which can be quickly taken out.

[0004] The existing device has some disadvantages during use. For example, the nucleic acid detection reagent cards in the above scheme are generally disposable. When testing a large number of people, it will be found that the number of antigen reagent cards used is too large, so the cost of use is high. The nucleic acid detection reagent card mainly relies on the detection paper inside the box body for detection operation, and the existing nucleic acid detection reagent cards are mostly integrated structures. It is difficult to take out the detection paper inside the box body for replacement, which is inconvenient to use. Utility Model Content

[0005] The utility model aims to provide a nucleic acid detection reagent card to solve the problem that nucleic acid detection reagent cards are generally disposable, and when testing a large number of people, it will be found that the number of antigen reagent cards used is too large, so the cost of use is high.

[0006] The utility model provides the following technical solution: a nucleic acid detection reagent card, comprising an upper shell and a lower shell, a first magnet is embedded at the edge of the lower end surface of the upper shell, a second magnet is embedded at the edge of the upper end surface of the lower shell, the upper shell and the lower shell are fixed by magnetic attraction of the first magnet and the second magnet, and two groups of pressing components for fixing detection paper are arranged on the inner bottom wall of the lower shell.

[0007] As a preferred embodiment of the above technical solution, the pressing assembly includes two damping shafts fixedly connected to the inner bottom wall of the upper shell, the two damping shafts are laterally symmetrically arranged, and a rotating plate is fixedly sleeved on the movable axis of the damping shaft, and a rubber pad is bonded to the lower end surface of the rotating plate.

[0008] As a preferred embodiment of the above technical solution, the rotating plate is rotated 0° or 90° through the damping shaft, the rotating plate is in a longitudinal state when it is rotated 0°, and is in a transverse state when it is rotated 90°.

[0009] As a preferred embodiment of the above technical solution, two liquid injection slots and two display slots are respectively provided on the upper shell body, and the liquid injection slots and display slots on the same horizontal axis are in the same group.

[0010] As a preferred embodiment of the above technical solution, two groups of auxiliary fixing bars are fixed on the inner top wall of the upper shell, each group of the auxiliary fixing bars has two, and the two auxiliary fixing bars in the same group are distributed on both sides of the display slot and the liquid injection slot in the same group.

[0011] As a preferred embodiment of the above technical solution, positioning columns are fixedly connected to the four corners of the lower end surface of the upper shell, and positioning holes are fixedly connected to the four corners of the upper end surface of the lower shell.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] In the utility model, the reagent card adopts a magnetic quick opening and closing design, which is convenient for quick opening and closing, and the disassembly process is simple and clear, and can be completed without special tools or skills. The detachable design makes the inside of the reagent card easy to clean, reduces the breeding of bacteria and pollutants, thereby improving the accuracy of the reagent card, and the reagent card can be recycled by simply replacing the test paper, reducing the cost of use. The reagent card adopts a modular design and can perform two tests at the same time. The two tests may involve different test indicators or methods, thereby providing richer test information and improving test accuracy. The test paper is fixed by a set pressing component, so as to avoid the test paper being offset during use and making it difficult to perform the test operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the three-dimensional structure of a nucleic acid detection reagent card;

[0015] Figure 2 This is a schematic diagram of the explosion structure of a nucleic acid detection reagent card;

[0016] Figure 3 This is a schematic diagram of the enlarged structure of a pressing component in a nucleic acid detection reagent card;

[0017] Figure 4 It is a schematic diagram of the structure of the upper shell in a nucleic acid detection reagent card.

[0018] In the figure: 10, upper shell; 101, liquid injection groove; 102, display groove; 11, lower shell; 12, first magnet; 13, second magnet; 14, positioning column; 15, positioning hole; 20, damping shaft; 21, rotating plate; 22, rubber pad; 30, auxiliary fixing strip. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0020] Example 1

[0021] like Figure 1 , Figure 2 and Figure 4As shown, the utility model provides a technical solution: a nucleic acid detection reagent card, including an upper shell 10 and a lower shell 11, a first magnet 12 is embedded at the edge of the lower end surface of the upper shell 10, and a second magnet 13 is embedded at the edge of the upper end surface of the lower shell 11. The upper shell 10 and the lower shell 11 are magnetically fixed by the first magnet 12 and the second magnet 13, and two groups of pressing components for fixing the detection paper are arranged on the inner bottom wall of the lower shell 11. During specific use, the upper shell 10 and the lower shell 11 in the reagent card adopt a magnetic quick opening and closing design, which is convenient for quick opening and closing, and the disassembly process is simple and clear. It can be completed without special tools or skills. The detachable design makes it easy to clean the inside of the reagent card, reducing the growth of bacteria and contaminants, thereby improving the accuracy of the reagent card. The reagent card can be recycled by simply replacing the test paper, reducing the cost of use. The reagent card adopts a modular design and can perform two tests at the same time. The two tests may involve different test indicators or methods, thereby providing richer test information and improving test accuracy. The test paper is fixed by a set pressing component to avoid the test paper from shifting during use and making it difficult to perform the test operation.

[0022] As an implementation method in this embodiment, Figure 2 and Figure 3 As shown, the pressing assembly includes two damping shafts 20 fixedly connected to the inner bottom wall of the upper shell 10, the two damping shafts 20 are laterally symmetrically arranged, and a rotating plate 21 is fixedly sleeved on the movable axis of the damping shaft 20, and a rubber pad 22 is bonded to the lower end surface of the rotating plate 21. During specific use, the rotating plate 21 is rotated 0° or 90° through the damping shaft 20. When the rotating plate 21 rotates 0°, it is in a longitudinal state. At this time, the rubber pad 22 on the rotating plate 21 is not above the detection paper, and the rubber pad 22 does not press and fix the detection paper. When the rotating plate 21 rotates 90°, it is in a horizontal state. At this time, the rubber pad 22 on the rotating plate 21 is above the detection paper, and the rubber pad 22 presses and fixes the detection paper, so as to avoid the detection paper from shifting during use.

[0023] As an implementation method in this embodiment, Figure 1 As shown, two liquid injection grooves 101 and two display grooves 102 are respectively provided on the upper shell 10. The liquid injection grooves 101 and the display grooves 102 on the same horizontal axis are in the same group. During specific use, the liquid of the dropper drips into the liquid injection groove 101, and the dripping liquid reacts after contacting the detection paper under the liquid injection groove 101, and finally the result is displayed in the display groove 102.

[0024] As an implementation method in this embodiment, Figure 4As shown, two groups of auxiliary fixing bars 30 are fixed on the inner top wall of the upper shell 10, and each group of auxiliary fixing bars 30 consists of two. The two auxiliary fixing bars 30 in the same group are distributed on both sides of the display slot 102 and the liquid injection slot 101 in the same group. When the upper shell 10 is magnetically fixed to the lower shell 11, the auxiliary fixing bars 30 further press and fix the two sides of the detection paper to prevent the detection paper from shifting during movement or use.

[0025] As an implementation method in this embodiment, Figure 1 and Figure 4 As shown, positioning columns 14 are fixedly connected to the four corners of the lower end surface of the upper shell 10, and positioning holes 15 are fixedly connected to the four corners of the upper end surface of the lower shell 11, so as to position the upper shell 10 and the lower shell 11 so that the upper shell 10 and the lower shell 11 will not move left and right.

[0026] Working principle: When in use, first place the detection paper on the inner bottom wall of the lower shell 11, and then swing the rotating plate 21. The rotating plate 21 rotates 90° through the damping shaft 20. When the rotating plate 21 rotates 90°, it is in a horizontal state. At this time, the rubber pad 22 on the rotating plate 21 is above the detection paper. The rubber pad 22 presses and fixes the detection paper to prevent the detection paper from shifting during use. Then, the positioning columns 14 on the four corners of the upper shell 10 are aligned with the positioning holes 15 and inserted. The upper shell 10 and the lower shell 11 are magnetically fixed by the first magnet 12 and the second magnet 13 to complete the assembly.

[0027] The above embodiments are only used to illustrate the technical solution of the present invention, but not to limit it.

Claims

1. A nucleic acid detection reagent card, comprising an upper shell (10) and a lower shell (11), characterized in that: A first magnet (12) is embedded at the edge of the lower end surface of the upper shell (10), and a second magnet (13) is embedded at the edge of the upper end surface of the lower shell (11). The upper shell (10) and the lower shell (11) are fixed by magnetic attraction via the first magnet (12) and the second magnet (13). Two groups of pressing components for fixing the detection paper are arranged on the inner bottom wall of the lower shell (11).

2. A nucleic acid detection reagent card according to claim 1, characterized in that: The pressing assembly comprises two damping shafts (20) fixedly connected to the inner bottom wall of the upper shell (10), the two damping shafts (20) being arranged laterally symmetrically, and a rotating plate (21) being fixedly sleeved on the movable axis of each of the damping shafts (20), and a rubber cushion (22) being bonded to the lower end surface of each of the rotating plates (21).

3. A nucleic acid detection reagent card according to claim 2, characterized in that: The rotating plate (21) rotates 0° or 90° via the damping shaft (20); the rotating plate (21) is in a longitudinal state when it rotates 0°, and is in a transverse state when it rotates 90°.

4. A nucleic acid detection reagent card according to claim 1, characterized in that: Two liquid injection slots (101) and two display slots (102) are respectively provided on the upper shell (10), and the liquid injection slots (101) and the display slots (102) on the same horizontal axis are in the same group.

5. A nucleic acid detection reagent card according to claim 2, characterized in that: Two groups of auxiliary fixing bars (30) are fixed on the inner top wall of the upper shell (10), each group of the auxiliary fixing bars (30) consists of two, and the two auxiliary fixing bars (30) in the same group are distributed on both sides of the display slot (102) and the liquid injection slot (101) in the same group.

6. A nucleic acid detection reagent card according to claim 1, characterized in that: Positioning columns (14) are fixedly connected at the four corners of the lower end surface of the upper shell (10), and positioning holes (15) are fixedly connected at the four corners of the upper end surface of the lower shell (11).

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