Mixing device for acetaminophen production

Abstract

The utility model relates to the field of medicine, discloses a mixing device for acetaminophen production, and solves the problems that when an existing mixing device is used for mixing, a motor is mainly adopted to drive stirring blades to rotate, the violent mixing action occurs everywhere, heat dissipation in the middle of a mixing cylinder needs to be slowly transmitted to the inner wall of the mixing cylinder, and the mixing effect is poor. The mixing device for acetaminophen production comprises a mixing cylinder, a reciprocating mechanism is arranged above the mixing cylinder, and a sliding mechanism is arranged at the lower end of the reciprocating mechanism. The reciprocating mechanism is started to drive the sliding mechanism to do reciprocating motion, liquid in the middle moves to the positions above the two sides to be mixed, compared with the prior art, heat can be taken away more quickly when a large amount of heat is released, and therefore the purpose that the heat dissipation effect is good is achieved.

Description

Technical Field

[0001] The utility model relates to the field of medicine, in particular to a mixing device for producing acetaminophen. Background Art

[0002] The invention discloses a mixing device for producing acetaminophen, which is a device for mixing acetaminophen and acetic acid (acetic anhydride) during the production process of acetaminophen.

[0003] The announcement number is CN113694051B, which discloses a method for preparing a coated tablet containing paracetamol and tramadol hydrochloride. The preparation method comprises the following steps: S1, mixing the active ingredient, filler and disintegrant to obtain a premixed powder. In the existing production process of paracetamol, the step of acetic anhydride acylation usually requires a mixing device. In this step, para-aminophenol and acetic acid (acetic anhydride) need to be mixed in a synthesis reactor to perform an acylation reaction, which generates a large amount of heat. Excessive heat can easily affect the mixing effect. However, when mixing, the existing mixing device mainly uses a motor to drive the stirring blade to rotate. The violent mixing action occurs everywhere, and the heat dissipation in the middle of the mixing barrel needs to be slowly transferred to the inner wall of the mixing barrel, resulting in low heat dissipation efficiency. Utility Model Content

[0004] The utility model aims to provide a mixing device for the production of acetaminophen. The device is used to work, thereby solving the problem that the existing mixing device mainly uses a motor to drive the stirring blade to rotate during mixing, and the violent mixing action occurs everywhere. The heat dissipation in the middle of the mixing cylinder needs to be slowly transferred to the inner wall of the mixing cylinder, resulting in low heat dissipation efficiency.

[0005] To achieve the above object, the utility model provides the following technical solution: a mixing device for producing acetaminophen, comprising a mixing cylinder, a reciprocating mechanism is arranged above the mixing cylinder, and a sliding mechanism is arranged at the lower end of the reciprocating mechanism;

[0006] The reciprocating mechanism includes a first support plate fixedly connected to the upper end of the mixing cylinder, the upper end of the first support plate is fixedly connected to a motor, the output end of the motor is fixedly connected to a rotating shaft, the other end of the rotating shaft is fixedly connected to a first rotating plate, a first connecting plate is arranged near the center of the mixing cylinder, a first guide hole is arranged inside the first connecting plate, a first guide rod is arranged inside the first guide hole, the first guide rod and the first rotating plate are connected in a fixed manner, a first hole is arranged inside the upper end of the mixing cylinder, a first push rod is arranged inside the first hole, and the first push rod and the first connecting plate are connected in a fixed manner.

[0007] Preferably, the appearance structure shapes of both ends of the first guide hole are straight lines, and the appearance structure of the middle end of the first guide hole is arc-shaped, and the matching mode of the first guide hole and the first guide rod is clearance matching.

[0008] Preferably, the inner side surface of the first hole is in contact with the outer side surface of the first push rod, and the central axis of the first push rod is perpendicular to the bottom surface of the mixing barrel.

[0009] Preferably, the sliding mechanism includes a second connecting plate fixedly connected to the lower end of the first push rod, a first groove is provided on the inner side of the second connecting plate, a second push rod is provided on the inner side of the first groove, the second push rod is fixedly connected to the supporting plate at one end away from the center of the mixing cylinder, a guide groove is provided on the inner wall of the mixing cylinder, two guide grooves are symmetrically provided about the central axis of the mixing cylinder, a point a is provided on the outer side of the upper end of the guide groove, a point b is provided on the inner side of the upper end of the guide groove, a point c is provided on the outer side of the lower end of the guide groove, a point d is provided on the outer side of the upper end of the guide groove, a second guide rod is provided on the inner side of the guide groove, the second guide rod is connected to the supporting plate in a fixed manner, the upper end of the supporting plate is fixedly connected to the second support plate, the inner side of the second support plate is rotatably connected to the third connecting plate, and the end of the third connecting plate away from the center of the mixing cylinder is fixedly connected to the baffle.

[0010] Preferably, the inner side surface of the first groove fits with the outer side surface of the second push rod, and the appearance structure shape of the second push rod is a rectangular parallelepiped.

[0011] Preferably, point a of the guide groove is closer to the central axis of the mixing cylinder than point b, and point d of the guide groove is closer to the central axis of the mixing cylinder than point c.

[0012] Preferably, the height of the lower plane of the baffle is lower than the inner side surface of the lower end of the supporting plate, and the height of the lower plane of the baffle is higher than the outer side surface of the lower end of the supporting plate.

[0013] The utility model provides a mixing device for acetaminophen production. The mixing device is provided with a reciprocating mechanism and a sliding mechanism, so that starting the reciprocating mechanism drives the sliding mechanism to perform reciprocating motion and mixes the liquid in the middle on both sides. Compared with the prior art, the heat can be taken away faster when a large amount of heat is released, thereby achieving the purpose of achieving a good heat dissipation effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the overall three-dimensional structure of the utility model;

[0015] Figure 2 This is a schematic diagram of the rear cross-sectional structure of the mixing cylinder of the utility model;

[0016] Figure 3 This is a schematic diagram of the rear cross-sectional structure of the guide groove of the utility model;

[0017] Figure 4 For the utility model Figure 2 Schematic diagram of the structure at point A in the middle.

[0018] In the figure: 1, mixing cylinder; 2, reciprocating mechanism; 3, sliding mechanism; 201, first support plate; 202, motor; 203, rotating shaft; 204, first rotating plate; 205, first connecting plate; 206, first guide hole; 207, first guide rod; 208, first hole; 209, first push rod; 301, second connecting plate; 302, first groove; 303, second push rod; 304, bearing plate; 305, guide groove; 306, second guide rod; 307, second support plate; 308, third connecting plate; 309, baffle. Specific implementation plan

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] See also Figure 1-Figure 4 The utility model provides a technical solution: a mixing device for producing acetaminophen, comprising a mixing cylinder 1, a reciprocating mechanism 2 is arranged above the mixing cylinder 1, and a sliding mechanism 3 is arranged at the lower end of the reciprocating mechanism 2;

[0021] The reciprocating mechanism 2 includes a first support plate 201 fixedly connected to the upper end of the mixing barrel 1, a motor 202 fixedly connected to the upper end of the first support plate 201, a rotating shaft 203 fixedly connected to the output end of the motor 202, a first rotating plate 204 fixedly connected to the other end of the rotating shaft 203, a first connecting plate 205 is provided on the first rotating plate 204 near the center of the mixing barrel 1, a first guide hole 206 is provided inside the first connecting plate 205, the appearance structure of the two ends of the first guide hole 206 is a straight line, and the appearance structure of the middle end of the first guide hole 206 is an arc, and the first guide hole 206 and the first guide rod 207 are matched in a clearance fit, so that the first guide rod 207 is on the inner side of the straight line of the first guide hole 206 When moving, the first connecting plate 205 can be driven to move up and down, and will not move up and down when moving on the inner side of the arc. A first guide rod 207 is arranged on the inner side of the first guide hole 206, and the connection method of the first guide rod 207 and the first rotating plate 204 is a fixed connection. A first hole 208 is arranged inside the upper end of the mixing cylinder 1, and a first push rod 209 is arranged on the inner side of the first hole 208. The connection method of the first push rod 209 and the first connecting plate 205 is a fixed connection. The inner side surface of the first hole 208 is fitted with the outer side surface of the first push rod 209, and the central axis of the first push rod 209 is perpendicular to the bottom surface of the mixing cylinder 1, so that the first push rod 209 can still seal the inner side of the mixing cylinder 1 when moving up and down.

[0022] The sliding mechanism 3 includes a second connecting plate 301 fixedly connected to the lower end of the first push rod 209, a first groove 302 is provided on the inner side of the second connecting plate 301, a second push rod 303 is provided on the inner side of the first groove 302, the inner side surface of the first groove 302 is fitted with the outer side surface of the second push rod 303, and the appearance structure shape of the second push rod 303 is a rectangular parallelepiped, so that the second push rod 303 does not rotate when moving inside the first groove 302, and the second push rod 303 is fixedly connected to the bearing plate 304 at one end away from the center of the mixing cylinder 1, a guide groove 305 is provided on the inner wall of the mixing cylinder 1, and two guide grooves 305 are symmetrically provided about the central axis of the mixing cylinder 1, a point a is provided on the outer side of the upper end of the guide groove 305, a point b is provided on the inner side of the upper end of the guide groove 305, a point c is provided on the outer side of the lower end of the guide groove 305, and a point d is provided on the outer side of the upper end of the guide groove 305, point a of the guide groove 305 is closer to the central axis of the mixing cylinder 1 than point b, and the guide groove 3 Point d of 05 is closer to the central axis of the mixing drum 1 than point c, so that when the second guide rod 306 moves to point 305a of the guide groove and moves downward, it can move to the side of the guide groove 305 close to the center of the mixing drum 1, and when the second guide rod 306 moves to point 305c of the guide groove and moves upward, it can move to the side of the guide groove 305 away from the center of the mixing drum 1. A second guide rod 306 is arranged on the inner side of the guide groove 305, and the second guide rod 306 is connected to the carrying plate 304 in a fixed manner. The upper end of the carrying plate 304 is fixedly connected to the second support plate 307, and the inner side of the second support plate 307 is rotatably connected to the third connecting plate 308. The end of the third connecting plate 308 away from the center of the mixing drum 1 is fixedly connected to a baffle 309, and the lower plane height of the baffle 309 is lower than the inner side surface of the lower end of the carrying plate 304, and the lower plane height of the baffle 309 is higher than the outer side surface of the lower end of the carrying plate 304, so that the baffle 309 can block one side of the carrying plate 304.

[0023] When mixing is required, the motor 202 is started to drive the rotating shaft 203 to rotate, so that the first rotating plate 204 and the first guide rod 207 rotate. Since the first guide rod 207 is arranged on the inner side of the first guide hole 206, the appearance structure of the two ends of the first guide hole 206 is linear, and the appearance structure of the middle end of the first guide hole 206 is arc-shaped, and the first guide hole 206 and the first guide rod 207 cooperate in a clearance fit, so that when the first guide rod 207 moves on the linear inner side of the first guide hole 206, it can drive the first connecting plate 205 to move up and down, and will not move up and down when moving on the arc inner side. When the first connecting plate 205 moves downward, it drives the first push rod 209 and the second connecting plate 301 to move downward, driving the second push rod 303 and the supporting plate 304 to move downward. 04 and the second guide rod 306 move downward, the water flow pushes the baffle 309 and the third connecting plate 308 to rotate back to the original position, and the liquid near the middle end of the mixing cylinder 1 is loaded into the inner side of the supporting plate 304 and the baffle 309. When the second guide rod 306 moves to point c, it moves upward, so that the second guide rod 306 moves to the side of the guide groove 305 away from the mixing cylinder 1, so that the baffle 309 is blocked by the inner wall of the mixing cylinder 1, and drives the liquid between the supporting plate 304 and the baffle 309 to move upward. When the second guide rod 306 moves to point a, the baffle 309 is opened under the impact of the liquid and moves downward along the inner wall of the mixing cylinder 1 for impact mixing. Because the violent mixing action occurs near the inner wall of the mixing cylinder 1, the large amount of heat generated can be immediately absorbed by the mixing cylinder 1 with a lower temperature, thereby improving the heat dissipation efficiency.

[0024] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0025] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A mixing device for producing acetaminophen, comprising a mixing cylinder (1), characterized in that: A reciprocating mechanism (2) is arranged above the mixing cylinder (1), and a sliding mechanism (3) is arranged at the lower end of the reciprocating mechanism (2); The reciprocating mechanism (2) comprises a first support plate (201) fixedly connected to the upper end of the mixing drum (1); the upper end of the first support plate (201) is fixedly connected to a motor (202); the output end of the motor (202) is fixedly connected to a rotating shaft (203); the other end of the rotating shaft (203) is fixedly connected to a first rotating plate (204); the first rotating plate (204) is provided with a first connecting plate (205) near the center of the mixing drum (1); the first connecting plate (205) is connected to the mixing drum (1); 05) is provided with a first guide hole (206) inside, a first guide rod (207) is provided on the inner side of the first guide hole (206), the first guide rod (207) is connected to the first rotating plate (204) in a fixed manner, a first hole (208) is provided inside the upper end of the mixing barrel (1), a first push rod (209) is provided on the inner side of the first hole (208), the first push rod (209) is connected to the first connecting plate (205) in a fixed manner.

2. A mixing device for producing acetaminophen according to claim 1, characterized in that: The appearance structure shapes of the two ends of the first guide hole (206) are straight lines, and the appearance structure of the middle end of the first guide hole (206) is arc-shaped, and the matching mode of the first guide hole (206) and the first guide rod (207) is clearance matching.

3. A mixing device for producing acetaminophen according to claim 1, characterized in that: The inner side surface of the first hole (208) fits the outer side surface of the first push rod (209), and the central axis of the first push rod (209) is perpendicular to the bottom surface of the mixing cylinder (1).

4. A mixing device for producing acetaminophen according to claim 1, characterized in that: The sliding mechanism (3) comprises a second connecting plate (301) fixedly connected to the lower end of the first push rod (209); a first groove (302) is arranged on the inner side of the second connecting plate (301); a second push rod (303) is arranged on the inner side of the first groove (302); an end of the second push rod (303) away from the center of the mixing cylinder (1) is fixedly connected to a bearing plate (304); a guide groove (305) is provided on the inner wall of the mixing cylinder (1); two guide grooves (305) are symmetrically arranged about the central axis of the mixing cylinder (1); a point a is arranged on the outer side of the upper end of the guide groove (305); and the guide groove ( A point b is arranged on the inner side of the upper end of the guide groove (305), a point c is arranged on the outer side of the lower end of the guide groove (305), a point d is arranged on the outer side of the upper end of the guide groove (305), a second guide rod (306) is arranged on the inner side of the guide groove (305), the second guide rod (306) is connected to the supporting plate (304) in a fixed manner, a second support plate (307) is fixedly connected to the upper end of the supporting plate (304), a third connecting plate (308) is rotatably connected to the inner side of the second support plate (307), and a baffle (309) is fixedly connected to the end of the third connecting plate (308) away from the center of the mixing barrel (1).

5. A mixing device for producing acetaminophen according to claim 4, characterized in that: The inner side surface of the first groove (302) fits the outer side surface of the second push rod (303), and the appearance structure shape of the second push rod (303) is a rectangular parallelepiped.

6. A mixing device for producing acetaminophen according to claim 4, characterized in that: Point a of the guide groove (305) is closer to the central axis of the mixing cylinder (1) than point b, and point d of the guide groove (305) is closer to the central axis of the mixing cylinder (1) than point c.

7. A mixing device for producing acetaminophen according to claim 4, characterized in that: The lower plane of the baffle (309) is lower than the inner side surface of the lower end of the carrier plate (304), and the lower plane of the baffle (309) is higher than the outer side surface of the lower end of the carrier plate (304).

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