Auxiliary operation device for 96-well plate

By designing the 96-well plate auxiliary operation device, using the combination of strip through holes and light shielding plates, the problem of the 96-well plate being easily added with wrong samples and not being able to avoid light in time when adding samples is solved, realizing instant coverage and indication of sample holes, and improving experimental efficiency and accuracy of results.

CN222795566UActive Publication Date: 2025-04-25CHONGQING MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202421462722.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-25
Publication Date
2025-04-25
Estimated Expiration
2034-06-25

AI Technical Summary

Technical Problem

The 96-well plate is prone to adding the wrong samples when adding samples, and cannot avoid light in time, which affects the experimental results.

Method used

A 96-well plate auxiliary operating device is designed, including an end cover covering the 96-well plate, with several strip through holes being opened on the end cover, each strip through hole corresponding to a row of sample holes, and is equipped with upper and lower layers of light shielding plates to achieve instant coverage and indication of sample holes.

Benefits of technology

Through the design of the light shielding plate, instant closure of sample holes is achieved, light damage is avoided, the possibility of sample errors is reduced, and the experimental efficiency and accuracy of results are improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model belongs to the technical field of experimental kits, and discloses a 96-well plate auxiliary operation device which comprises an end cover covering a 96-well plate, a plurality of strip-shaped through holes are formed in the end cover, each strip-shaped through hole corresponds to a row of sample holes, a first opening communicated with the strip-shaped through holes is formed in one side of the end cover, and a second opening communicated with the strip-shaped through holes is formed in the other side of the end cover. A second opening communicated with the strip-shaped through hole is formed in the other side of the end cover; the end cover is slidably connected with an upper-layer light shielding plate and a lower-layer light shielding plate which are used for covering the strip-shaped through hole, and the lower-layer light shielding plate is located under the upper-layer light shielding plate; the 96-well plate solves the problems that the existing 96-well plate is easy to add a wrong sample and cannot timely keep away from light.
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Description

Technical Field

[0001] The utility model relates to the technical field of experimental reagent kits, in particular to a 96-well plate auxiliary operation device. Background Art

[0002] The 96-well plate is a widely used experimental consumable material with a large usage volume. It can be used for biochemical analysis and cell experiments in pharmaceutical research and development, such as polymerase chain reaction. A typical structure of a 96-well plate includes a rectangular well plate body and a sample well integrally formed on the well plate body. The bottom of the sample well is closed, and a container with a certain volume can be formed for sample addition. Among them, 96 blind holes are opened on the plate well body. The 96 blind holes are divided into 12 columns, and each column has 8 blind holes. The distance between two adjacent blind holes in the vertical or horizontal direction is the same.

[0003] However, there are no obvious markings between the wells of the 96-well plate, and several problems will be encountered when adding various reagents: First, when adding samples, you need to concentrate on counting or remembering the positions of the wells you want to add, and you may easily get tired and dizzy during the operation, which may lead to adding samples to the wrong wells and causing sample waste; second, some wells need to be protected from light after adding samples, but experimenters cannot operate in a dark room, so these wells that have been added with reagents have to be exposed to light, and they have to wait until all the wells are processed before they can be covered with lids to avoid light, which may affect the experimental results; third, for some experiments with a small number of samples, experimenters only need to operate certain columns of sample wells, but it is not easy to find which wells have samples. Utility Model Content

[0004] The utility model aims to provide a 96-well plate auxiliary operation device to solve the problems that the existing 96-well plate is easy to add wrong samples and cannot be protected from light in time.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] The basic technical solution provided by the utility model is:

[0007] A 96-well plate auxiliary operation device comprises an end cover covering the 96-well plate, the end cover being provided with a plurality of strip-shaped through holes, and each of the strip-shaped through holes corresponds to a column of sample wells, a first opening communicating with the strip-shaped through holes is provided on one side of the end cover, and a second opening communicating with the strip-shaped through holes is provided on the other side of the end cover; an upper light shielding plate and a lower light shielding plate for covering the strip-shaped through holes are slidably connected to the end cover, and the lower light shielding plate is located directly below the upper light shielding plate.

[0008] Principles of basic technical solutions:

[0009] Each strip-shaped through hole corresponds to a column of sample holes, and the sample holes are exposed, which is convenient for adding samples from the strip holes into the sample holes. A first opening connected to the strip-shaped through hole is provided on one side wall of the end cover, which is convenient for the upper light shielding plate to slide in or out of the end cover. A second opening is provided on the side wall of the end cover opposite to the first opening, which is convenient for the lower light shielding plate to slide in or out of the end cover. The lower light shielding plate is located below the upper light shielding plate, so that the lower light shielding plate can be pulled to expose a sample hole. After adding the sample, the upper light shielding plate can be pushed to cover the sample hole.

[0010] The beneficial effects of the basic technical solution are:

[0011] (1) By setting two layers of shading plates, it is possible to cover one sample hole when adding one sample, so that light can be avoided in time during the experiment, thereby increasing the accuracy of the experimental results; in addition, the shading plate also serves as an indicator. The experimental operator can know which sample hole the sample is added to according to the position of the shading plate, without having to remember the position of a sample hole specifically. It is easy to use and is not easy to add the wrong sample, which reduces the workload of the experimenter and improves the experimental efficiency;

[0012] (2) The sample wells with added samples are all covered by the upper light shielding plate, while the sample wells without added samples are only covered by the lower light shielding plate. For experiments with a small number of samples, the experimenter can easily find a few rows of sample wells to operate based on the light shielding plate;

[0013] (3) The materials used in the device of the utility model are easy to obtain and inexpensive, and the device is simple to manufacture and easy to use.

[0014] Preferably, first sliding grooves adapted to the thickness of the upper light shielding plate are formed on both side walls of the strip-shaped through hole, and the upper light shielding plate is slidably connected in the first sliding grooves.

[0015] Through the above arrangement, the first slide groove is adapted to the thickness of the upper shading plate, and only the slide groove needs to be opened on the end cover, which reduces the process flow, facilitates manufacturing, and is easy to use; and the upper and lower walls of the slide groove can also limit the up and down movement of the shading plate.

[0016] Preferably, the two side walls of the strip-shaped through hole are further provided with second slide grooves adapted to the thickness of the lower shading plate, the second slide grooves are located directly below the first slide grooves, and the lower shading plate is slidably connected in the second slide grooves.

[0017] Through the above-mentioned setting, the second slide groove is adapted to the thickness of the lower light shielding plate, and only the slide groove needs to be opened on the end cover, which reduces the process flow, facilitates manufacturing and is easy to use; and the upper and lower walls of the slide groove can also limit the up and down movement of the lower light shielding plate; and the lower slide groove is located directly below the upper slide groove, which is convenient for processing and manufacturing.

[0018] Preferably, the first slide groove has the same size as the second slide groove; the first opening has the same size as the second opening.

[0019] Through the above arrangement, the first slide groove and the second slide groove have the same size, which is easy to manufacture, and the upper shading plate and the lower shading plate can be used alternately. In case the upper shading plate or the lower shading plate is lost, there can be a replacement; the first opening and the second opening have the same size, and the shading plate can slide into the slide groove from the first opening or the second opening, increasing the convenience of use.

[0020] Preferably, the size of the end cap is larger than that of a 96-well plate.

[0021] Through the above arrangement, the size of the end cap is larger than that of the 96-well plate, so that the end cap can be covered on the 96-well plate to fix the end cap, and the operation is simple.

[0022] Preferably, the number of the strip-shaped through holes is 12.

[0023] Through the above arrangement, there are 12 strip-shaped through holes, that is, the length direction of the strip-shaped through holes extends along the width direction of the 96-well plate. In this way, the length of the light shielding plate is shorter, which is convenient for manufacturing, and the space occupied during the experiment is smaller, saving space.

[0024] Preferably, one end of the shading plate is connected to a handle, and the handle is provided with an anti-slip protrusion.

[0025] Through the above arrangement, a handle is provided to facilitate pushing and pulling of the sunshade, and an anti-skid protrusion is provided on the sunshade to prevent slipping.

[0026] Preferably, the upper end and the side end of the strip-shaped through hole of the end cover are provided with indicator marks for marking the order of the sample holes.

[0027] The above arrangement makes it easy to identify the position of the sample hole.

[0028] Preferably, the upper shading plate and the lower shading plate are both made of polyvinyl chloride.

[0029] Through the above arrangement, polyvinyl chloride is easily available at a low price. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 This is a structural schematic diagram of a 96-well plate auxiliary operation device and a 96-well plate combination of the utility model;

[0031] Figure 2 For the utility model Figure 1 A is an enlarged schematic diagram;

[0032] Figure 3The utility model is a top view of a combination of a 96-well plate auxiliary operation device and a 96-well plate;

[0033] Figure 4 A structural schematic diagram of a 96-well plate auxiliary operation device of the utility model;

[0034] Figure 5 The utility model is a front view of a 96-well plate auxiliary operation device;

[0035] Figure 6 This is the utility model Figure 5 Enlarged schematic diagram of B

[0036] Figure 7 Schematic diagram of the structure of a 96-well plate auxiliary operation device combined with a 96-well plate Figure 2 ;

[0037] The names of the corresponding marks in the accompanying drawings are:

[0038] 96-well plate 1, sample well 12, end cover 2, strip through hole 21, first slide groove 221, second slide groove 222, first opening 23, second opening 24, upper shading plate 31, lower shading plate 32, handle 33. DETAILED DESCRIPTION

[0039] The present invention is further described in detail below in conjunction with the accompanying drawings and implementation examples:

[0040] like Figures 1 to 7As shown, a 96-well plate auxiliary operation device includes an end cap 2 covering the 96-well plate 1, the size of the end cap 2 is larger than the size of the 96-well plate, so that the end cap can be covered on the 96-well plate, 12 strip through holes 21 are opened on the end cap 2, and each strip through hole 21 corresponds to a row of sample wells 12, and the upper end and side end of the strip through hole 21 of the end cap 2 are provided with an indication mark for marking the order of the sample wells 12, one side of the end cap 2 is provided with a first opening 23 connected to the strip through hole 21, and the other opposite side of the end cap 2 is provided with a second opening 24 connected to the strip through hole 21; an upper light shielding plate 31 and a lower light shielding plate 32 for covering the strip through hole 21 are slidably connected to the end cap 2, wherein the material of the upper light shielding plate 31 and the lower light shielding plate 32 is Both are made of polyvinyl chloride, and the two side walls of the strip through hole 21 are provided with a first slide groove 221 that is adapted to the thickness of the upper light shielding plate 31, and the upper light shielding plate 31 is slidably connected in the first slide groove 221. The two side walls of the strip through hole 21 are also provided with a second slide groove 222 that is adapted to the thickness of the lower light shielding plate 32, and the second slide groove 222 is located directly below the first slide groove 221, and the lower light shielding plate 32 is slidably connected in the second slide groove 222, and the lower light shielding plate 32 is located directly below the upper light shielding plate 31; and the first slide groove 221 and the second slide groove 222 have the same size; the first opening 23 and the second opening 24 have the same size; and one end of the upper light shielding plate 31 and one end of the lower light shielding plate 32 are both connected with a handle 33, and an anti-slip protrusion is provided on the handle 33.

[0041] The specific implementation process is as follows:

[0042] Put the end cover 2 on the 96-well plate 1, pull the lower light shielding plate 32 to expose a sample well 12, so as to know which sample well 12 to add to, and then add the sample into the sample. After adding the sample, push the upper light shielding plate 31 to cover the sample well 12. The experimenter can know which position the sample is added to according to the position of the sample well 12 exposed by the lower light shielding plate 32. After adding, the experimenter can know which columns have been added with samples according to the position covered by the upper light shielding plate 31; among them, the upper light shielding plate corresponding to the sample well that does not need to add samples can be removed to avoid taking up space.

[0043] Among them, by setting two layers of shading plates, it can be achieved that one sample hole 12 is covered when a sample is added, and light can be avoided in time during the experiment, thereby increasing the accuracy of the experimental results; and the shading plate also serves as an indicator. The experimental operator can know which sample hole 12 the sample is added to according to the position of the shading plate, and does not need to specially remember the position of the previous sample hole 12. It is easy to use and is not easy to add the wrong sample, which reduces the workload of the experimenter and improves the experimental efficiency; the sample holes 12 with added samples are all covered by the upper shading plate 31, while the sample holes 12 without added samples are only covered by the lower shading plate 32. For some experiments with a small number of samples, the experimenter can easily find a few columns of sample holes 12 to be operated according to the shading plate; the materials used in the device of the utility model are easy to obtain and low in price, and the device is simple to manufacture and easy to use.

[0044] The above is only an embodiment of the utility model, and the common knowledge such as the known specific technical scheme or characteristics in the scheme is not described in detail here. It should be pointed out that for those skilled in the art, several deformations and improvements can be made without departing from the technical scheme of the utility model, which should also be regarded as the protection scope of the utility model, and these will not affect the effect of the implementation of the utility model and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A 96-well plate auxiliary operation device, characterized in that: It includes an end cover covering a 96-well plate, wherein the end cover is provided with a plurality of strip-shaped through holes, and each of the strip-shaped through holes corresponds to a column of sample holes, a first opening connected to the strip-shaped through holes is provided on one side of the end cover, and a second opening connected to the strip-shaped through holes is provided on the other side of the end cover; an upper light shielding plate and a lower light shielding plate for covering the strip-shaped through holes are slidably connected to the end cover, and the lower light shielding plate is located directly below the upper light shielding plate.

2. The 96-well plate auxiliary operation device according to claim 1, characterized in that: The two side walls of the strip-shaped through hole are provided with first sliding grooves adapted to the thickness of the upper light shielding plate, and the upper light shielding plate is slidably connected in the first sliding grooves.

3. The 96-well plate auxiliary operation device according to claim 2, characterized in that: The two side walls of the strip-shaped through hole are also provided with second slide grooves adapted to the thickness of the lower shading plate, the second slide grooves are located directly below the first slide grooves, and the lower shading plate is slidably connected in the second slide grooves.

4. The 96-well plate auxiliary operation device according to claim 3, characterized in that: The first slide groove has the same size as the second slide groove; the first opening has the same size as the second opening.

5. The 96-well plate auxiliary operation device according to claim 1, characterized in that: The size of the end cap is larger than that of a 96-well plate.

6. The 96-well plate auxiliary operation device according to claim 1, characterized in that: The number of the strip-shaped through holes is 12.

7. The 96-well plate auxiliary operation device according to claim 1, characterized in that: One end of the upper shading plate and one end of the lower shading plate are both connected with a handle, and an anti-slip protrusion is arranged on the handle.

8. The 96-well plate auxiliary operation device according to claim 1, characterized in that: The upper end and the side end of the strip-shaped through hole of the end cover are provided with indication marks for marking the sequence of the sample holes.

9. The 96-well plate auxiliary operation device according to claim 1, characterized in that: The upper shading plate and the lower shading plate are made of polyvinyl chloride.