Centrifugal mechanism and cell separation equipment

Abstract

The utility model relates to the technical field of medical instruments, in particular to a centrifugal mechanism which comprises a centrifugal cup and a centrifugal seat, the centrifugal cup can be placed on the centrifugal seat, an ejection mechanism is installed at the top of the centrifugal seat, the centrifugal cup is located above the ejection mechanism, and the ejection mechanism comprises a lower plate, a movable plate and an upper plate which are arranged from bottom to top. A plurality of ejector rods are arranged on the movable plate, the movable plate can be driven by a driving part to move up and down, and when the movable plate moves upwards, the ejector rods penetrate through the upper plate to jack up the centrifugal cup upwards. The centrifugal cup can be mounted in the cell separation equipment and can be ejected out, so that the centrifugal cup is greatly convenient to disassemble. And through a magnetic attraction structure of the centrifugal cup and the centrifugal seat, the installation is convenient.

Description

Technical Field

[0001] The utility model relates to the technical field of medical instruments, in particular to a centrifugal mechanism and cell separation equipment. Background Art

[0002] Cell separation is a vital experimental technique in biology and medicine, which aims to extract specific types of cells from a mixture or tissue for subsequent analysis, research or application. In this process, centrifugation is indispensable.

[0003] Centrifuges play a key role in the cell separation process. Centrifugation uses the centrifugal force generated by the high-speed rotation of the solution around the axis to cause some components to precipitate while others remain in the supernatant. The centrifugal mechanism enables the solution to be efficiently centrifuged. Specifically, when the centrifugal mechanism starts working, the cell mixture is placed in the centrifuge cup and rotates at high speed with the centrifuge cup. Due to the different densities and masses of different components, they will separate under the action of centrifugal force. Cells, as one of the components, will be separated according to their unique density and size and deposited on the bottom or side wall of the centrifuge cup.

[0004] The current centrifuge mechanism generally has the problem of inconvenient removal and placement of the centrifuge cup. Excessive force will affect the connection between the centrifuge cup and the centrifuge seat, and may even cause excessive shaking of the solution in the centrifuge cup, resulting in failure of the centrifugal operation. Summary of the invention

[0005] In order to solve the above problems, the utility model provides a centrifugal mechanism and a cell separation device using the centrifugal mechanism. The centrifugal cup of the centrifugal mechanism is convenient to take and put. The technical solution adopted by the utility model is as follows:

[0006] A centrifugal mechanism comprises a centrifugal cup and a centrifugal seat, wherein the centrifugal cup can be placed on the centrifugal seat, an ejection mechanism is installed on the top of the centrifugal seat, the centrifugal cup is located above the ejection mechanism, the ejection mechanism comprises a lower plate, a movable plate and an upper plate arranged from bottom to top, a plurality of ejector rods are arranged on the movable plate, the movable plate can be driven by a driving member to move up and down, and when the movable plate moves upward, the ejector rods pass through the upper plate to lift the centrifugal cup upward.

[0007] In the centrifugal mechanism, the upper plate and the lower plate are provided with a plurality of support columns, each support column is provided with a linear bearing, and the movable plate is passed through the linear bearing.

[0008] In the above centrifugal mechanism, the centrifugal cup and the centrifugal seat are magnetically connected.

[0009] In the above centrifugal mechanism, the bottom of the centrifugal cup is provided with a plurality of magnetic protrusions, and the top of the centrifugal seat is provided with a plurality of magnetic grooves, and the protrusions and the grooves are matched one by one.

[0010] In the above centrifugal mechanism, the driving member is an electric push rod, which is located on the side of the centrifugal seat, and the telescopic end of the electric push rod is connected to the movable plate.

[0011] The utility model also provides a cell separation device, comprising a box body, a control panel, an operation screen and a weighing module, wherein the box body is provided with the centrifugal mechanism as described above.

[0012] The beneficial effects of the utility model are as follows: the centrifugal cup can be ejected, which greatly facilitates the disassembly of the centrifugal cup. The magnetic attraction structure of the centrifugal cup and the centrifugal seat facilitates installation. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 This is a schematic diagram of the centrifugal mechanism of the first embodiment of the utility model;

[0014] Figure 2 This is a schematic diagram of a centrifugal seat according to Embodiment 1 of the present utility model;

[0015] Figure 3 This is a schematic diagram of the ejection mechanism of the first embodiment of the utility model;

[0016] Figure 4 A schematic diagram of a movable plate of an ejection mechanism according to a first embodiment of the utility model;

[0017] Figure 5 This is a schematic diagram of the bottom of a centrifugal cup according to Embodiment 1 of the present utility model;

[0018] Figure 6 This is a schematic diagram of a cell separation device according to Embodiment 2 of the present utility model.

[0019] In the figure: 1 is a centrifugal cup, 2 is a centrifugal seat, 3 is a lower plate, 4 is an upper plate, 5 is a movable plate, 6 is an electric push rod, 7 is a support column, 8 is a push rod, 9 is a linear bearing, 10 is a groove, 11 is a convex block, 21 is an operation screen, 22 is a control panel, and 23 is a weighing module. DETAILED DESCRIPTION

[0020] The technical solution of the utility model is described in detail below in conjunction with the accompanying drawings.

[0021] Embodiment 1

[0022] The present embodiment is a centrifugal mechanism, including a centrifugal cup 1 and a centrifugal seat 2. The centrifugal cup 1 can be placed on the centrifugal seat 2. The centrifugal seat 2 is driven by a servo motor and can be designed with a 3D printed integrated structure, which saves man-hours and is easy to process. An ejection mechanism is installed on the top of the centrifugal seat 2. The centrifugal cup 1 is located above the ejection mechanism. The ejection mechanism includes a lower plate 3, a movable plate 5 and an upper plate 4 arranged from bottom to top. Several ejector rods are arranged on the movable plate 5. The movable plate 5 can be driven up and down by a driving member. When the movable plate 5 moves upward, the ejector rod passes through the upper plate 4 to lift the centrifugal cup 1 upward.

[0023] The centrifugal mechanism described above has several support columns 7 on the upper plate 4 and the lower plate 3, each of which has a linear bearing 9 (see Figure 4 , only one linear bearing 9 is shown. In actual use, the support column 7 is equipped with a linear bearing 9 , and the movable plate 5 is inserted into the linear bearing 9 .

[0024] In the centrifugal mechanism, the centrifugal cup 1 and the centrifugal seat 2 are connected magnetically. The bottom of the centrifugal cup 1 is provided with a plurality of magnetic protrusions 11, and the top of the centrifugal seat 2 is provided with a plurality of magnetic grooves 10, and the protrusions 11 and the grooves 10 are matched one by one.

[0025] In the centrifugal mechanism, the driving member is an electric push rod 6 , which is located at the side of the centrifugal seat 2 , and the telescopic end of the electric push rod 6 is connected to the movable plate 5 .

[0026] Embodiment 2

[0027] This embodiment is a cell separation device, comprising a housing, a control panel 22, an operation screen 21 and a weighing module 23. The housing is provided with the centrifugal mechanism in the first embodiment.

[0028] The box of this cell separation equipment adopts sheet metal structure, and the overall design structure is compact and easy to process. In addition to the centrifugal mechanism, the box is also equipped with a refrigeration module. The refrigeration adopts TEC refrigeration to keep the temperature in the cavity within the temperature control range of 4-40 degrees. The top of the box is set as the main operation panel, and the aluminum plate is bent to fix the clamp valve, peristaltic pump and other liquid path devices. The overall installation is convenient and lightweight, and it can be removed and installed as a whole module. This device is equipped with an 11-inch folding capacitive operation screen 21, which is convenient for operation and control. The bottom is also equipped with a barcode scanner for wireless Bluetooth or USB communication. The bottom of the device is equipped with a waste liquid tray, which can hold 300ml waste liquid bags to collect waste liquid generated in the cavity under unexpected circumstances. The whole machine is equipped with 2 power control buttons, an Internet port, and two USB communication ports for easy maintenance and subsequent updates.

Claims

1. A centrifugal mechanism, comprising a centrifugal cup (1) and a centrifugal seat (2), wherein the centrifugal cup (1) can be placed on the centrifugal seat (2), and characterized in that: An ejection mechanism is installed on the top of the centrifugal seat (2), and the centrifugal cup (1) is located above the ejection mechanism. The ejection mechanism comprises a lower plate (3), a movable plate (5) and an upper plate (4) arranged from bottom to top. A plurality of ejector rods (8) are provided on the movable plate (5). The movable plate (5) can be driven by a driving member to move up and down. When the movable plate (5) moves upward, the ejector rods (8) pass through the upper plate (4) to lift the centrifugal cup (1) upward.

2. The centrifugal mechanism according to claim 1, characterized in that: The upper plate (4) and the lower plate (3) are provided with a plurality of support columns (7), each support column (7) is provided with a linear bearing (9), and the movable plate (5) is inserted into the linear bearing (9).

3. The centrifugal mechanism according to claim 1, characterized in that: The centrifugal cup (1) and the centrifugal seat (2) are magnetically connected.

4. The centrifugal mechanism according to claim 1, characterized in that: The bottom of the centrifugal cup (1) is provided with a plurality of magnetic protrusions (11), and the top of the centrifugal seat (2) is provided with a plurality of magnetic grooves (10), wherein the protrusions (11) match the grooves (10) one by one.

5. The centrifugal mechanism according to claim 1, characterized in that: The driving member is an electric push rod (6), which is located on the side of the centrifugal seat (2), and the telescopic end of the electric push rod (6) is connected to the movable plate (5).

6. A cell separation device, characterized in that: It comprises a box, a control panel (22), an operating screen (21) and a weighing module, wherein the box is provided with a centrifugal mechanism as claimed in any one of claims 1 to 5.

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