Device for adding multiple groups of liquid samples
By designing a multi-group liquid sample loading device for biotechnology experiments, the problems of low efficiency and safety hazards of multi-group sample loading in the prior art are solved, and an efficient, accurate and safe sample loading process is achieved.
Patent Information
- Application Number
- CN202421462304.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-25
- Publication Date
- 2025-04-25
- Estimated Expiration
- 2034-06-25
AI Technical Summary
In biotechnology experiments, the efficiency of adding samples from multiple groups of samples in the prior art is low, which can easily lead to changes in the physical and chemical properties of the reagent, affect the accuracy of the experimental results, and there are safety risks in operation.
A device for filling samples of multiple sets of liquid samples is designed, including an infusion pump, a filling pipe, a filling section, a plug, a drop head and a stent. By setting up multiple sample loading sections on the sample loading main pipe, each sample loading section can be connected to the plug or drip head, and the infusion pump provides the delivery power of the sample loading reagent, so as to achieve simultaneous or step-by-step sample loading.
The work efficiency and accuracy of sample additions of multiple groups of samples are improved, the safety of the sample addition process is ensured, the experimental personnel are avoided from directly contacting high-risk reagents, saving manpower and material resources, and improving the safety factor.
Smart Images
Figure CN222795597U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of biological experimental equipment, in particular to a device for adding samples of multiple groups of liquid samples. Background Art
[0002] In biotechnology experiments, it is often necessary to add samples to multiple test tubes separately. For example, to extract active ingredients from biological samples, it is necessary to quantitatively add reagents to multiple groups of samples and then connect to the subsequent extraction process.
[0003] In the prior art, a single tube is generally used for sequential sample addition. However, in actual operation, this method of sample addition has some problems. First, if a large amount of reagent needs to be added, the sample addition efficiency will be low. When processing a large number of samples, there will be a large time difference in sequential sample addition, which will lead to various errors such as changes in the physical and chemical properties of the reagents, affecting the accuracy of the experimental results. Second, high-risk reagents such as boiling distilled water, strong acids, and strong bases are often used during the experiment. Blindly increasing the sample addition speed can easily cause laboratory safety accidents and create dangers. Utility Model Content
[0004] The technical problem to be solved by the utility model is how to improve the working efficiency of adding multiple groups of samples in biotechnology experiments, and to improve the accuracy of experimental results and process safety.
[0005] To achieve the above object, the utility model provides a device for adding multiple groups of liquid samples, comprising:
[0006] Infusion pumps;
[0007] A sample adding main pipe, the outlet of the infusion pump is connected to the sample adding main pipe through a pipeline, and the sample adding main pipe is provided with a plurality of liquid outlets along the extension direction;
[0008] A plurality of sample adding sections, each of which is installed on the sample adding main pipe, each of which corresponds to one of the liquid outlets, and each of which is provided with a sample adding port, which is communicated with the corresponding liquid outlet;
[0009] At least one plug;
[0010] at least one drip head;
[0011] The plug or the dripping head is provided at the sample adding port of each sample adding section, a dripping port is provided at the bottom of the dripping head, and a valve is provided on the dripping head.
[0012] The utility model provides a plurality of sample adding sections on the sample adding main pipe, and the sample adding sections can be freely selected to be connected with a plug or a dripping head, and the dripping head is arranged at a corresponding position of a container to be sampled, and the infusion pump provides the sample adding reagent delivery power, thereby realizing simultaneous or step-by-step sample adding of multiple tubes, improving the working efficiency and accuracy of sample adding of multiple groups of samples, and ensuring the safety of the sample adding process.
[0013] Furthermore, the sample adding section is provided with an external thread on the outer wall near the sample adding port, the top of the plug is provided with an internal thread, the top of the dripping head is provided with an internal thread, and the plug and the dripping head are threadedly connected to the sample adding section. The plug and the dripping head are connected to the sample adding section through a threaded structure, which is convenient for disassembly and assembly, has good sealing performance, and prevents leakage at the sample adding port.
[0014] Furthermore, the lower part of the dropper head is a conical tip structure, which makes it easy to control the amount of sample added.
[0015] Furthermore, the valve is a plug valve, which is easy to open and close and can adjust the sample addition speed.
[0016] Furthermore, the material of the dripping head and the plug is acid and alkali resistant plastic. The dripping head and the plug are light, easy to disassemble and assemble, and not easy to be damaged.
[0017] Furthermore, the sample adding section includes an annular connecting portion, which is sleeved on the sample adding main pipe and has an interference fit with the sample adding main pipe. The sample adding section adopts a sleeve structure, which is easy to disassemble and assemble, so that the liquid outlet is aligned with the sample adding port, and the interference fit ensures that the sample adding section is installed stably.
[0018] Furthermore, the device further comprises at least one bracket, and the sample adding main pipe is arranged on the bracket. The bracket is arranged to position the sample adding main pipe so that the sample adding port has a certain height.
[0019] Furthermore, the support comprises a telescopic rod. The height of the support is adjustable, so that the sample loading height can be adjusted to meet the use requirements.
[0020] Furthermore, the device also includes a liquid container, and the inlet of the infusion pump is connected to the liquid container through a pipeline. Providing a matching liquid container is conducive to the stable infusion of the infusion pump.
[0021] Furthermore, the liquid container is made of a transparent material, and scale lines are provided on the surface of the liquid container, thereby facilitating real-time readings during experiments and more accurately controlling the amount of sample added.
[0022] In summary, the present invention has the following beneficial effects compared with the prior art:
[0023] The invention provides a sample adding device with multiple sample adding ports, which has a simple structure, is easy to use and maintain, and a plug or a dripping head can be optionally set at the sample adding port. An infusion pump is used to provide sample adding power, and multiple tubes can be added simultaneously or in steps. The sample adding process is safe and stable, and there is no need to pipette sample reagents multiple times, which avoids direct contact of experimenters with reagents. The sample adding amount can also be accurately controlled, thereby improving the efficiency of sample adding of multiple groups of samples in biotechnology experiments, saving manpower and material resources, and improving the safety factor. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 It is a structural diagram of a device for adding multiple groups of liquid samples in an embodiment.
[0025] Figure 2 It is a partial cross-sectional view of the sample adding main pipe in the embodiment.
[0026] Figure 3 It is a structural diagram of the sample adding section in the embodiment.
[0027] Figure 4 It is a structural diagram of the plugging dripping head in the embodiment.
[0028] Figure 5 Schematic diagram of the structure of the dripping head in the embodiment.
[0029] Description of reference numerals:
[0030] 1-sample adding main pipe, 11-liquid outlet, 2-sample adding section, 21-sample adding port, 22-connecting part, 3-plug, 4-drip head, 5-valve, 6-infusion pump, 61-infusion tube, 7-bracket, 71-telescopic rod, 8-liquid container, 81-scale line. DETAILED DESCRIPTION
[0031] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the technical scheme in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Generally, the components of the embodiments of the utility model described and shown in the drawings here can be arranged and designed in various different configurations.
[0032] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the present invention to be protected, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0033] It should be noted that similar symbols and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not require further definition and explanation in the subsequent drawings.
[0034] In the description of the present utility model, it should be noted that the terms "upper", "lower", "left", "right", "inside", "outside", "front", "back", etc. indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, or are the directions or positional relationships in which the utility model product is usually placed when in use. They are only for the convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present utility model.
[0035] Combination Figures 1 to 5 As shown, this embodiment discloses a device for adding multiple groups of liquid samples, including a sample addition main pipe 1, multiple sample addition sections 2, multiple plugs 3, multiple drip heads 4 and an infusion pump 6. The inlet of the infusion pump 6 is connected to the liquid sample through the infusion pipe 61, and the outlet is connected to the sample addition main pipe 1 through the infusion pipe 61. The infusion pump 6 is used to transport sample reagents to the sample addition main pipe 1 and provide a sample addition power. The sample addition main pipe 1 is provided with multiple liquid outlets 11 along the extension direction. In this embodiment, the number of liquid outlets 11 is 18, the opening direction is downward, and the liquid outlets 11 are evenly distributed; in other embodiments, the number of liquid outlets 11 can be adjusted, generally 3 to 18, and the opening direction can be toward the side. The number of the sample adding sections 2 is the same as the liquid outlet 11. Each sample adding section 2 is installed on the sample adding main pipe 1. The position of each sample adding section 2 corresponds to a liquid outlet 11. The sample adding port 21 is provided at the bottom of the sample adding section 2. The sample adding port 21 is connected to the corresponding liquid outlet 11. The liquid sample in the sample adding main pipe 1 can flow out from the sample adding port 21. The number of the plugs 3 and the dripping heads 4 is the same as the total number of the sample adding sections 2. The position of the sample adding port 21 of each sample adding section 2 is provided with a plug 3 or a dripping head 4. The plug 3 is used to close the sample adding port 21, and the corresponding sample adding section 2 cannot discharge liquid. The dripping head 4 is provided with a dripping port at the bottom. The dripping head 4 is provided with a valve 5 for closing or opening the liquid channel of the dripping head 4. When the valve 5 is opened, the liquid in the sample adding main pipe 1 flows out from the dripping head 4 to realize the sample adding operation.
[0036] The above-mentioned sample adding device is provided with a plurality of sample adding sections 2 on the sample adding main pipe 1, each sample adding section 2 can be freely installed with a plug 3 or a dropper 4, and the dropper 4 is arranged at the corresponding position of the container to be added during the experiment, and the infusion pump 6 provides the sample adding reagent delivery power, and the valves 5 of the plurality of dropper heads 4 can be opened at the same time to achieve multi-tube simultaneous sample addition, or the valves 5 of each dropper head 4 can be opened in sequence to perform multi-tube step-by-step sample addition. Since multiple sampling operations are not required, the sample adding device can greatly improve the work efficiency and accuracy of multiple groups of sample addition, and at the same time avoid direct contact of the experimenter with the reagent, ensuring the safety of the sample addition process.
[0037] Combination Figure 1 As shown, the sample addition device provided in this embodiment also includes a liquid container 8, and the inlet of the infusion pump 6 is connected to the liquid container 8 through an infusion tube 61. Before the sample addition operation, the required reagent is first transferred to the liquid container 8 that matches the infusion pump 6, and then the infusion pump 6 transports the sample from the liquid container 8 to the sample addition main tube 1 to ensure stable liquid delivery. Preferably, the liquid container 8 is a transparent material, such as glass, acid and alkali resistant plastic, etc., and the surface of the liquid container 8 is provided with a scale line 81, which is convenient for real-time reading during the experiment and more accurately controlling the sample addition amount. And the power of the infusion pump 6 is adjustable, which is convenient for adjusting the sample addition speed according to the number of opened drip heads 4.
[0038] The sample loading device provided in this embodiment also includes three brackets 7 for supporting the sample loading main pipe 1. In this embodiment, the three brackets 7 are respectively arranged on the left and right sides and the middle of the sample loading main pipe 1. In other embodiments, the number and position of the brackets 7 can be adjusted, generally 2 to 6. The sample loading main pipe 1 enters the groove at the top of the bracket 7. The bracket 7 makes the sample loading main pipe 1 have a certain height as a whole, which is convenient for loading samples into the container. Preferably, the bracket 7 includes a telescopic rod 71, the height of which can be freely adjusted, so that the setting height of the sample loading main pipe 1 can be adjusted to meet the use needs.
[0039] Combination Figure 3 As shown, the sample adding section 2 includes an annular connecting portion 22, which is sleeved on the sample adding main pipe 1. The sample adding section 2 adopts a sleeve structure, which is convenient for disassembly and assembly, and convenient for position adjustment, to ensure that the liquid outlet 11 on the sample adding main pipe 1 is aligned with the sample adding port 21. Preferably, the connecting portion 22 and the sample adding main pipe 1 have an interference fit, providing a large friction force, to ensure that the sample adding section 2 is stably installed and will not slide.
[0040] The sample adding section 2 is provided with an external thread on the outer wall near the sample adding port 21. Figure 4 and Figure 5 As shown, the top of the plug 3 and the top of the drip head 4 are provided with internal threads matching the sample adding section 2, so that the plug 3 / dripping head 4 is connected to the sample adding section 2 through a threaded structure, which is convenient for disassembly and assembly, reliable in connection, and has good sealing performance, effectively preventing leakage at the sample adding port 21.
[0041] Combination Figure 4 As shown, the lower part of the dripping head 4 is a conical tip structure, which is convenient for controlling the amount of sample added. The valve 5 is a plug valve, which is easy to open and close, and can adjust the sample addition speed.
[0042] Since the dripping head 4 and the plug 3 need to be frequently disassembled, the dripping head 4 and the plug 3 of this embodiment are made of PTFE. In other embodiments, other acid- and alkali-resistant plastics can also be selected to ensure that the dripping head 4 and the plug 3 are light in weight, easy to disassemble, and not easily damaged. The sample adding section 2 and the sample adding main pipe 1 can also be made of the same acid- and alkali-resistant plastic to make the sample adding device as a whole lighter and easier to move and arrange.
[0043] The sample adding device provided in the above embodiment has a simple structure, is easy to use and maintain, can realize simultaneous or step-by-step sample adding of multiple tubes, the sample adding process is safe and stable, and the sample adding amount can be accurately controlled. It can improve the efficiency of sample adding of multiple groups of samples in biotechnology experiments, save manpower and material resources, and improve the safety factor, and has great application and promotion value.
[0044] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in the field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model.
Claims
1. A device for adding multiple groups of liquid samples, characterized in that: include: Infusion pump (6); A sample adding main pipe (1), the outlet of the infusion pump (6) is connected to the sample adding main pipe (1) through a pipeline, and the sample adding main pipe (1) is provided with a plurality of liquid outlets (11) along the extension direction; A plurality of sample adding sections (2), each of the sample adding sections (2) being mounted on the sample adding main pipe (1), each of the sample adding sections (2) corresponding to one of the liquid outlets (11), the sample adding sections (2) being provided with a sample adding port (21), the sample adding port (21) being in communication with the corresponding liquid outlet (11); at least one plug (3); at least one dripping head (4); The plug (3) or the dripping head (4) is provided at the position of the sample adding port (21) of each sample adding section (2), a dripping port is provided at the bottom of the dripping head (4), and a valve (5) is provided on the dripping head (4).
2. The device for adding multiple groups of liquid samples according to claim 1, characterized in that: The sample adding section (2) is provided with an external thread on its outer wall near the sample adding port (21), the top of the plug (3) is provided with an internal thread, the top of the dripping head (4) is provided with an internal thread, and the plug (3) and the dripping head (4) are threadedly connected to the sample adding section (2).
3. The device for adding multiple groups of liquid samples according to claim 1, characterized in that: The lower part of the dripping head (4) is a conical pointed mouth structure.
4. The device for adding multiple groups of liquid samples according to claim 1, characterized in that: The valve (5) is a plug valve.
5. The device for adding multiple groups of liquid samples according to any one of claims 1 to 4, characterized in that: The material of the dripping head (4) and the plug (3) is acid- and alkali-resistant plastic.
6. The device for adding multiple groups of liquid samples according to claim 1, characterized in that: The sample adding section (2) comprises an annular connecting portion (22), wherein the connecting portion (22) is sleeved on the sample adding main pipe (1) and is interference fit with the sample adding main pipe (1).
7. The device for adding multiple groups of liquid samples according to claim 1, characterized in that: It also comprises at least one support (7), and the sample adding main tube (1) is arranged on the support (7).
8. The device for adding multiple groups of liquid samples according to claim 7, characterized in that: The support (7) comprises a telescopic rod (71).
9. The device for adding multiple groups of liquid samples according to claim 1, characterized in that: It also comprises a liquid container (8), and the inlet of the infusion pump (6) is connected to the liquid container (8) through a pipeline.
10. The device for adding multiple groups of liquid samples according to claim 9, characterized in that: The liquid container (8) is made of a transparent material, and a scale line (81) is provided on the surface of the liquid container (8).