Incubation and detection integrated system
By designing an incubation detection integration system in a chemiluminescence immunoassay, and using some incubation holes on the tray as the detection holes, the problems of large size and low detection efficiency of traditional analyzers are solved, and simple structure, high integration and high efficiency detection are achieved.
Patent Information
- Application Number
- CN202421537066.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-01
- Publication Date
- 2025-04-25
- Estimated Expiration
- 2034-07-01
AI Technical Summary
The modules of the traditional chemiluminescence immunoassay are independently set up, resulting in large volume, low detection efficiency, and complex incubation structure, which increases the movement stroke of the local handle.
A incubation detection integration system is designed, using the partial incubation hole position on the outermost ring on the tray as the detection hole position, and a detection window is set on the side of the tray, so that the detection module can directly complete analysis and detection, simplify the structure, improve integration and compactness.
It realizes the advantages of simple structure, high integration and compact product. At the same time, the moving stroke of the handle in the analyzer is optimized, the detection efficiency is improved, and the rotation accuracy and stability are improved through the direct drive mechanism of the motor.
Smart Images

Figure CN222800450U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a chemiluminescent immunoassay analyzer, in particular to an incubation detection integrated system. Background Art
[0002] Chemiluminescent immunoassay is a new type of labeled immunoassay technology that combines chemiluminescence or bioluminescence with immune response to detect trace amounts of antigens or antibodies. Chemiluminescent immunoassay technology is more environmentally friendly and safer than traditional radioimmunoassay, and has higher sensitivity and a wider detection range than enzyme-linked immunosorbent assay. Chemiluminescent immunoassay is widely recognized for its environmentally friendly, rapid, and accurate characteristics, and has become the main means of clinical immunodiagnosis.
[0003] In the physical structure of the chemiluminescent immunoassay analyzer, many modules such as filling, mixing, incubation, washing and detection are involved. In traditional analyzers, each module is usually independently arranged at different stations, which has the defects of bulky volume and low detection efficiency. With the continuous development of technology, in order to improve the detection efficiency, some systems combining multiple functional modules have appeared on the market, such as the Chinese patent document with announcement number CN217156539U, which records an incubation detection module, which includes a supporting shell, and a tray with a cylindrical structure is rotatably installed inside the supporting shell. By setting the incubation hole in the middle area of the tray and separately setting the detection station at the edge of the tray, the incubation and detection functions are integrated into one module. Although this module reduces the volume of the overall structure and improves the compactness of the system, it will complicate the structure of the module and increase the moving stroke of the local gripper. Therefore, the incubation structure needs to be further optimized. Utility Model Content
[0004] In view of this, the utility model provides an incubation detection integrated system, which directly uses part of the incubation wells as detection wells, and has the advantages of simple structure, high integration and compact product.
[0005] To achieve the above purpose, the technical solution of the utility model is as follows:
[0006] An incubation detection integrated system includes a cabin and a tray rotatably arranged inside the cabin, wherein a driving mechanism for driving the tray to rotate is provided at the bottom of the cabin, and the key points are:
[0007] The tray is constructed as a cylindrical structure, on which a plurality of circles of incubation holes are arranged in a circular array, wherein at least one of the incubation holes located in the outermost circle is defined as a detection hole position, and a detection window is provided on the side of the tray, which is directly opposite to and connected to the lower part of the detection hole position, and the detection window exposes the lower part of the reaction cup located in the detection hole position;
[0008] The side of the cabin is provided with an assembly notch, and a detection module is fixedly installed at the position of the assembly notch. The light-emitting detection element of the detection module faces the interior of the cabin and is arranged at the same height as the detection window.
[0009] By adopting the above structure, part of the incubation holes in the outermost circle are directly used as detection holes, and a detection window is set at the position corresponding to the detection hole on the side of the tray, so that the detection module can directly complete the analysis and detection work, which has the advantages of simple structure, high integration and compact product.
[0010] As a preferred embodiment, a support step is provided on the upper part of the detection hole, and the support step is used to stably place the reaction cup in the detection hole. The above structure improves the stability of the detection.
[0011] As a preference: a mounting shaft passing downwardly out of the cabin body is provided at the bottom of the tray, an annular support portion extending upward is provided at the bottom of the cabin body, and the mounting shaft is rotatably assembled in the annular support portion through a bearing;
[0012] The driving mechanism is a motor, and the output shaft of the motor is coaxially sleeved at the bottom of the mounting shaft. With the above structure, the output shaft of the motor rotates, which can directly drive the tray to rotate, and has the technical advantages of high rotation accuracy and strong stability.
[0013] As a preferred embodiment, a positioning code disc is coaxially sleeved at the lower part of the installation shaft. With the above structure, each hole position on the tray can be rotated grid by grid according to a preset center angle.
[0014] Preferably, the bearings are provided in two groups.
[0015] Preferably, two circles of incubation holes are distributed on the tray.
[0016] Preferably, the number of the detection holes is set to four groups, and the four groups of detection holes are evenly distributed.
[0017] Compared with the prior art, the beneficial effects of the utility model are:
[0018] 1. The incubation detection integrated system provided by the utility model directly utilizes part of the incubation holes in the outermost circle as detection holes, and sets a detection window at the position corresponding to the detection hole on the side of the tray, so that the detection module can directly complete the analysis and detection work, which has the advantages of simple structure, high integration and compact product. At the same time, it can also optimize the moving stroke of the gripper in the analyzer and improve the detection efficiency.
[0019] 2. The incubation detection integrated system provided by the utility model drives the tray to rotate by direct motor drive, which has the technical advantages of high rotation accuracy and strong stability. At the same time, such a driving mechanism has a simple structure, reduces the probability of mechanical failure, and facilitates maintenance. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 It is a schematic diagram of the structure of the incubation detection integrated system;
[0021] Figure 2 It is a cross-sectional view of the incubation detection integrated system (the detection hole position 2b is not in the detection module 4 position);
[0022] Figure 3 It is a cross-sectional view of another state of the incubation detection integrated system (the detection hole position 2b is located at the detection module 4 position);
[0023] Figure 4 It is a schematic diagram of the structure of the tray 2. DETAILED DESCRIPTION
[0024] The utility model is further described below in conjunction with embodiments and drawings.
[0025] like Figure 1 and 4 As shown, an incubation and detection integrated system includes a cabin 1, a tray 2 is rotatably installed inside the cabin 1, and a driving mechanism 3 capable of driving the tray 2 to rotate is provided at the bottom of the cabin 1. The tray 2 is constructed as a cylindrical structure, and is provided with a plurality of circles of incubation holes 2a distributed in a circular array, and the incubation holes 2a are used to place reaction cups b. Since the incubation and detection integrated system provided in this embodiment is a compact and miniaturized system, in this embodiment, two circles of incubation holes 2a are arranged on the tray 2, wherein at least one of the incubation holes 2a located in the outermost circle is defined as a detection hole position 2b. A detection window 2c is provided on the side of the tray 2, which is opposite to and connected to the lower part of the detection hole position 2b, and the detection window 2c exposes the lower part of the reaction cup b located in the detection hole position 2b. In combination with Figure 3 As shown, the side of the chamber 1 is provided with an assembly notch 1a, and the detection module 4 is fixedly installed at the position of the assembly notch 1a. The light-emitting detection element 4a of the detection module 4 faces the inside of the chamber 1 and is arranged at the same height as the detection window 2c. When the reaction cup b to be tested on the detection hole 2b stops at the position of the detection module 4, the light-emitting detection element 4a can face the detection window 2c of the detection hole 2b, and the light-emitting detection element 4a can work to complete the analysis and detection.
[0026] Based on the above structural design, the outermost incubation holes 2a are directly used as the detection holes 2b, and the detection window 2c is set at the position corresponding to the detection hole 2b on the side of the tray 2. Without the need for additional layout and setting of detection stations, the two functions of incubation and detection can be more reasonably integrated into one module, which has the advantages of simple structure, high integration and compact product. At the same time, it can also optimize the moving stroke of the gripper in the analyzer and improve the detection efficiency.
[0027] Further, such as Figure 2 and 3 As shown, a support step a is provided on the upper part of the incubation hole 2a and the detection hole 2b. The support step a can enable the reaction cup b to be stably placed in the detection hole 2b, thereby improving the stability of the detection.
[0028] Please refer to Figure 3 and 4 In this embodiment, among the incubation holes 2a located in the outermost circle, there are four detection holes 2b, and the four detection holes 2b are evenly distributed on the circumference and radially symmetrical with respect to the two detection holes 2b. With such a design, the number of detection holes 2b is increased through reasonable layout, and at the same time, the moving stroke of the gripper in the analyzer is conveniently optimized, further improving the detection efficiency.
[0029] Re-attend Figure 2 and 3 , a mounting shaft 2d passing through the cabin 1 downward is provided at the bottom of the tray 2, and an annular support portion 1b extending upward is provided at the bottom of the cabin 1, and the mounting shaft 2d is rotatably assembled in the annular support portion 1b through a bearing b. In this embodiment, the driving mechanism 3 is a motor, and the output shaft 3a of the motor is coaxially sleeved at the bottom of the mounting shaft 2d. The output shaft 3a of the motor rotates, which can directly drive the tray 2 to rotate, and has the technical advantages of high rotation accuracy and strong stability, and is particularly suitable for equipment with high position accuracy requirements such as chemiluminescence immunoassay analyzers. At the same time, such a driving mechanism has a simple structure, reduces the probability of mechanical failure, and is convenient for maintenance.
[0030] In this embodiment, the number of bearings b is two, which can further reduce the friction loss between the mounting shaft 2d and the annular support portion 1b and protect the components from damage.
[0031] For example Figure 3 As shown, the lower part of the mounting shaft 2d is fixedly sleeved with a positioning code disc 5, which is coaxially arranged with the mounting shaft 2d. With such a design, the positioning code disc 5 can identify the rotation angle of the tray 2, so that each hole position on the tray 2 can rotate one by one according to the preset center angle.
[0032] Finally, it should be noted that the above description is only a preferred embodiment of the present invention. Under the guidance of the present invention, ordinary technicians in this field can make a variety of similar expressions without violating the purpose and claims of the present invention, and such changes fall within the scope of protection of the present invention.
Claims
1. An incubation detection integrated system, comprising a chamber (1) and a tray (2) rotatably arranged inside the chamber (1), wherein a driving mechanism (3) for driving the tray (2) to rotate is provided at the bottom of the chamber (1), characterized in that: The tray (2) is constructed as a cylindrical structure, and is provided with a plurality of circles of incubation holes (2a) distributed in a circular array, wherein at least one of the incubation holes (2a) located in the outermost circle is defined as a detection hole position (2b), and a detection window (2c) is provided on the side of the tray (2) and is directly opposite to and connected to the lower part of the detection hole position (2b), and the detection window (2c) exposes the lower part of the reaction cup located in the detection hole position (2b); The side of the cabin (1) is provided with an assembly notch (1a), and a detection module (4) is fixedly installed at the position of the assembly notch (1a). The light-emitting detection element (4a) of the detection module (4) faces the interior of the cabin (1) and is arranged at the same height as the detection window (2c).
2. The incubation detection integrated system according to claim 1, characterized in that: A supporting step (a) is provided on the upper portion of the detection hole (2b), and the supporting step (a) is used to stably place the reaction cup in the detection hole (2b).
3. The incubation detection integrated system according to claim 1, characterized in that: The bottom of the tray (2) is provided with a mounting shaft (2d) penetrating downwardly out of the cabin (1); the bottom of the cabin (1) is provided with an annular support portion (1b) extending upwardly; the mounting shaft (2d) is rotatably assembled in the annular support portion (1b) via a bearing (b); The driving mechanism (3) is a motor, and the output shaft (3a) of the motor is coaxially sleeved on the bottom of the mounting shaft (2d).
4. The incubation detection integrated system according to claim 3, characterized in that: A positioning code disc (5) is coaxially sleeved at the lower part of the installation shaft (2d).
5. The incubation detection integrated system according to claim 3, characterized in that: The bearings (b) are provided in two groups.
6. The incubation detection integrated system according to claim 1, characterized in that: Two circles of incubation holes (2a) are distributed on the tray (2).
7. The incubation detection integrated system according to claim 1, characterized in that: The number of the detection holes (2b) is set to four groups, and the four groups of detection holes (2b) are evenly distributed.
Citation Information
Patent Citations
Incubation detection module
CN217156539U