Multi-cabin cell activity detection kit

Abstract

The multi-cabin cell viability detection kit comprises a kit body, a plurality of cabins are arranged in the kit body, a water bath mechanism is arranged in each cabin, the water bath mechanism comprises a water bath box, an opening is formed in the top of the water bath box, and the water bath box is provided with a water inlet and a water outlet. A reagent tube is inserted into the opening, the bottom end of the reagent tube extends into the water bath box, and an electric heating rod and a temperature sensor are mounted on the inner wall of the water bath box. According to the utility model, a multi-cabin design is adopted, each cabin is provided with an independent water bath mechanism, incubation experiments of a plurality of cell samples can be simultaneously carried out, the experiment efficiency and throughput are greatly improved, in addition, each water bath mechanism is provided with an independent control panel, a user can independently set the water bath temperature of each cabin according to experiment requirements, and the experiment efficiency is greatly improved. Different environment temperature conditions are simulated, and a more flexible and diversified experiment environment is provided for cell activity detection.

Description

Technical Field

[0001] The utility model relates to the technical field of reagent kits, and in particular to a multi-chamber cell viability detection reagent kit. Background Art

[0002] In cell biology, drug development, and clinical diagnosis, cell viability testing is a key step in evaluating cell survival status, functional integrity, and drug responsiveness. Accurate assessment of cell viability is essential for understanding cell behavior, optimizing experimental conditions, and predicting drug efficacy. In the process of cell viability testing, a kit with an incubation system is required to incubate the cells. The incubation step is an important step to ensure that the reagents are in full contact with the cells and react. Traditional cell viability detection methods, such as the MTT method and the CCK-8 method, require cells to be incubated under specific conditions so that the reagents can enter the cells and react with metabolites or enzymes in the cells to produce detectable signals.

[0003] When some existing cell viability detection kits are used, the reagent tubes thereon are mostly placed in the same chamber, and the incubation temperature of each reagent tube cannot be individually regulated.

[0004] For example, a cell viability detection kit disclosed in the announcement number CN215753840U, when in use, the cell viability detection kit of the patent is turned on by a control switch, the blower, the temperature sensor, and the heater, the blower absorbs the surrounding air, and transmits it into the box body through the heating of the heater, so that the temperature in the box body is maintained at 37 degrees, and then three sample tubes are taken for cell viability detection experiment; then the three sample tubes are placed in the placement slot, and the electric push rod is turned on by the control switch, the electric push rod is extended to drive the fixing clamp to move, so that the sample tubes are clamped and fixed, and the box cover is closed after fixing, and the time for incubating cells is set by the stopwatch, during the incubation period, the staff can directly view the sample tubes in the box body through the observation window, when the temperature sensor detects that the temperature in the box body drops, the temperature sensor controls the blower and the heater to work, so as to ensure that the box body is always maintained at 37 degrees; when the time for incubating cells is up, the stopwatch controls the speaker to issue an alarm, so as to remind the staff to take the sample tube out of the box body, after taking it out, all electrical appliances are turned off by the control switch, and the three sample tubes are compared to obtain accurate test results.

[0005] The patented cell viability test kit is designed to incubate and detect cell viability at a constant temperature of 37 degrees. However, all sample tubes are placed inside the box, and the ambient temperature of each sample tube is the same. It is impossible to adjust the incubation temperature of each sample tube separately, and it is impossible to simulate the effect of different ambient temperatures on cell activity.

[0006] Therefore, it is necessary to invent a multi-chamber cell viability detection kit to solve the above problems. Utility Model Content

[0007] The utility model aims to provide a multi-chamber cell viability detection kit to solve the problems in the above-mentioned technology.

[0008] In order to achieve the above-mentioned purpose, the utility model provides the following technical solutions: a multi-chamber cell viability detection kit, comprising a box body, wherein a cabin is provided inside the box body, and the number of the cabins is set to be multiple, and a water bath mechanism is arranged inside each of the cabins, and the water bath mechanism comprises a water bath box, and the water bath box has an opening at the top, and a reagent tube is inserted into the opening, and the bottom end of the reagent tube extends into the water bath box, an electric heating rod and a temperature sensor are installed on the inner wall of the water bath box, a power plug is installed at the bottom of the water bath box, and a power socket is installed on the inner bottom surface of the cabin, the power plug is plugged into the power socket, and the electric heating rod and the temperature sensor are electrically connected to the power plug, and a control panel is installed on the front of the box body, and the power socket is electrically connected to the control panel.

[0009] The multi-chamber design allows multiple cell samples to be processed simultaneously, improving experimental efficiency. The water bath mechanism set in each chamber provides a constant temperature environment for the cells, helping to maintain the stability of cell viability.

[0010] Preferably, the plurality of cabins are distributed in a linear array, and an acrylic transparent sealing plate is installed on the top of each cabin.

[0011] The chambers are arranged in a linear array, making it easy for users to observe and manage multiple samples; the design of the acrylic transparent sealing plate allows users to observe the cell status without opening the chamber, reducing the risk of contamination.

[0012] Preferably, the number of the control panels is equal to the number of the water bath mechanisms, and the plurality of control panels are respectively arranged in one-to-one correspondence with the plurality of water bath mechanisms.

[0013] Each water bath mechanism is equipped with an independent control panel, which allows users to control the temperature of each chamber individually, providing flexibility in experimental conditions.

[0014] Preferably, a rubber sealing ring is fixedly connected to the inner wall of the opening, and the rubber sealing ring is interference-connected with the outer wall of the reagent tube.

[0015] The rubber sealing ring ensures a good seal between the reagent tube and the water bath, preventing water evaporation and external contamination, and ensuring the accuracy of the experiment.

[0016] Preferably, handles are fixedly connected to both sides of the top of the water bath, and pads are fixedly connected to the four corners of the bottom of the water bath.

[0017] A handle on top of the water bath allows users to lift and move the water bath for cleaning and maintenance, while raised blocks help maintain the stability of the water bath.

[0018] Preferably, a receiving groove is provided inside the box body, a battery is installed inside the receiving groove, and the battery is electrically connected to a power socket.

[0019] The built-in battery allows the test kit to be used without an external power source, enhancing the portability of the device and the flexibility of usage scenarios.

[0020] Preferably, a heat dissipation hole is opened on the back side of the box body, and the heat dissipation hole is communicated with the accommodating groove.

[0021] The design of the heat dissipation holes helps to discharge the heat generated by equipment such as batteries to ensure the normal operation of the equipment.

[0022] Preferably, a power interface is installed on one side of the box body, and the power interface is electrically connected to the battery.

[0023] The power interface allows the user to charge the battery via an external power source.

[0024] In the above technical solution, the technical effects and advantages provided by the utility model are:

[0025] 1. It adopts a multi-chamber design, each of which is equipped with an independent water bath mechanism, which can carry out incubation experiments of multiple cell samples at the same time, greatly improving the efficiency and throughput of the experiment. In addition, each water bath mechanism is equipped with an independent control panel. Users can set the water bath temperature of each chamber separately according to experimental requirements, simulate different ambient temperature conditions, and provide a more flexible and diverse experimental environment for cell viability detection;

[0026] 2. By providing handles on both sides of the top of the water bath, the user can easily lift the water bath from the cabin, making it easier to clean the inside of the water bath. In addition, pads are fixed at the four corners of the bottom of the water bath, which not only helps to maintain the stability of the water bath, but also keeps the power plug at the bottom of the water bath suspended to prevent the power plug from coming into contact with foreign objects. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic diagram of the overall structure of the utility model from a first viewing angle;

[0028] Figure 2 This is a schematic diagram of the overall structure of the utility model from a second viewing angle;

[0029] Figure 3 This is a schematic diagram of the overall structure of the transparent acrylic sealing plate of the utility model when it is opened;

[0030] Figure 4 It is a structural sectional view of the utility model;

[0031] Figure 5 This is a schematic diagram of the structure of the water bath of the utility model from the first perspective;

[0032] Figure 6 This is a schematic structural diagram of the water bath of the utility model from a second viewing angle.

[0033] Description of reference numerals:

[0034] 1. Box body; 2. Water bath mechanism; 3. Water bath box; 4. Opening; 5. Reagent tube; 6. Electric heating rod; 7. Temperature sensor; 8. Power plug; 9. Power socket; 10. Control panel; 11. Acrylic transparent sealing plate; 12. Handle; 13. Heightening block; 14. Battery; 15. Heat dissipation hole; 16. Power interface; 17. Rubber sealing ring. DETAILED DESCRIPTION

[0035] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0036] The utility model provides Figure 1-6 A multi-chamber cell viability detection kit shown in the figure includes a box body 1, a cabin is opened inside the box body 1, the number of cabins is set to be multiple, a water bath mechanism 2 is arranged inside each cabin, the water bath mechanism 2 includes a water bath box 3, an opening 4 is opened at the top of the water bath box 3, a reagent tube 5 is plugged into the opening 4, and the bottom end of the reagent tube 5 extends into the water bath box 3, an electric heating rod 6 and a temperature sensor 7 are installed on the inner wall of the water bath box 3, a power plug 8 is installed at the bottom of the water bath box 3, a power socket 9 is installed on the bottom surface of the cabin, the power plug 8 is plugged into the power socket 9, the electric heating rod 6 and the temperature sensor 7 are electrically connected to the power plug 8, a control panel 10 is installed on the front of the box body 1, and the power socket 9 is electrically connected to the control panel 10.

[0037] In one aspect of the present embodiment, the multiple cabins are distributed in a linear array, and an acrylic transparent sealing plate 11 is installed on the top of each cabin. The number of control panels 10 is equal to the number of water bath mechanisms 2, and the multiple control panels 10 are respectively arranged in a one-to-one correspondence with the multiple water bath mechanisms 2. A rubber sealing ring 17 is fixedly connected to the inner wall of the opening 4, and the rubber sealing ring 17 is interference-connected with the outer wall of the reagent tube 5. Handles 12 are fixedly connected to both sides of the top of the water bath 3, and pads 13 are fixedly connected to the four corners of the bottom of the water bath 3. A accommodating groove is opened inside the box body 1, and a battery 14 is installed inside the accommodating groove, and the battery 14 is electrically connected to the power socket 9. A heat dissipation hole 15 is opened on the back of the box body 1, and the heat dissipation hole 15 is connected to the accommodating groove. A power interface 16 is installed on one side of the box body 1, and the power interface 16 is electrically connected to the battery 14.

[0038] Working principle of this utility model:

[0039] Refer to the instruction manual Figure 1-6 When using the utility model, firstly, inject a proper amount of clean water into each water bath box 3, and pay attention that the water level should not be too high to avoid overflow, and put the water bath box 3 filled with water into the compartment inside the box body 1, and ensure that the power plug 8 of each water bath box is correctly plugged into the corresponding power socket 9;

[0040] Insert the prepared reagent tube 5 into the opening 4 at the top of the water bath 3, making sure that the bottom of the reagent tube 5 is completely immersed in water, close the acrylic transparent sealing plate 11 above each water bath 3, and ensure that the incubation environment is in a sealed state. The design of the acrylic transparent sealing plate 11 allows the user to observe the changes of the cell sample from the outside without opening the water bath;

[0041] Plug the plug of the external power cord into the power interface 16 on one side of the box body 1 to charge the built-in battery 14. The battery 14 will provide power to the power socket 9, and then power the electric heating rod 6 and the temperature sensor 7 in each water bath mechanism 2. Through the control panel 10 corresponding to each water bath mechanism 2, the working state of the electric heating rod 6 is set and controlled to heat the water inside the water bath box 3. At the same time, the temperature sensor 7 will monitor the water temperature in real time and feed the data back to the control panel 10. The user can control the water temperature at a certain set temperature through the control panel 10 according to the experimental requirements to simulate different ambient temperature conditions;

[0042] When the water temperature reaches the set value and remains stable, the cell sample in the reagent tube 5 will begin to be incubated, and the user can observe the changes of the cell sample through the acrylic transparent sealing plate 11. Since each water bath mechanism 2 is equipped with an independent control panel 10, cell samples under different temperature conditions can be incubated and observed at the same time;

[0043] After the incubation is completed, the reagent tube 5 is taken out from the water bath 3 and the cell activity is tested. By comparing the test results of the cell samples under different temperature conditions, the effect of the incubation temperature on the cell activity is analyzed.

[0044] Through the above steps, users can make full use of the multi-chamber cell viability assay kit to conduct efficient cell viability assay experiments and deeply analyze the effect of incubation temperature on cell activity.

Claims

1. A multi-chamber cell viability detection kit, comprising a box body (1), characterized in that: The box body (1) is provided with a cabin, the number of the cabins is set to be multiple, each of the cabins is provided with a water bath mechanism (2), the water bath mechanism (2) comprises a water bath box (3), the top of the water bath box (3) is provided with an opening (4), a reagent tube (5) is inserted into the opening (4), the bottom end of the reagent tube (5) extends into the water bath box (3), an electric heating rod (6) and a temperature sensor (7) are installed on the inner wall of the water bath box (3), a power plug (8) is installed at the bottom of the water bath box (3), a power socket (9) is installed on the bottom surface of the cabin, the power plug (8) is plugged into the power socket (9), the electric heating rod (6) and the temperature sensor (7) are both electrically connected to the power plug (8), and a control panel (10) is installed on the front of the box body (1), and the power socket (9) is electrically connected to the control panel (10).

2. A multi-chamber cell viability detection kit according to claim 1, characterized in that: The plurality of chambers are distributed in a linear array, and an acrylic transparent sealing plate (11) is installed on the top of each chamber.

3. A multi-chamber cell viability detection kit according to claim 1, characterized in that: The number of the control panels (10) is equal to the number of the water bath mechanisms (2), and the plurality of control panels (10) are respectively arranged in one-to-one correspondence with the plurality of water bath mechanisms (2).

4. A multi-chamber cell viability detection kit according to claim 1, characterized in that: A rubber sealing ring (17) is fixedly connected to the inner wall of the opening (4), and the rubber sealing ring (17) is interference-connected to the outer wall of the reagent tube (5).

5. A multi-chamber cell viability detection kit according to claim 1, characterized in that: Handles (12) are fixedly connected to both sides of the top of the water bath (3), and padding blocks (13) are fixedly connected to the four corners of the bottom of the water bath (3).

6. A multi-chamber cell viability detection kit according to claim 1, characterized in that: A receiving groove is provided inside the box body (1), a storage battery (14) is installed inside the receiving groove, and the storage battery (14) is electrically connected to the power socket (9).

7. A multi-chamber cell viability detection kit according to claim 6, characterized in that: A heat dissipation hole (15) is provided on the back of the box body (1), and the heat dissipation hole (15) is communicated with the accommodating groove.

8. A multi-chamber cell viability detection kit according to claim 6, characterized in that: A power interface (16) is installed on one side of the box body (1), and the power interface (16) is electrically connected to the storage battery (14).

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