Perforating inspection system for oral osmotic pump controlled release tablets for laboratory

Abstract

The utility model relates to an oral osmotic pump controlled release tablet punching inspection system for a laboratory, a driving device is arranged on a system main frame body, the driving output end of the driving device faces upwards, a plurality of medicine placing cavities are formed in medicine placing rotary tables, the multiple medicine placing cavities are arranged around the central axis of the medicine placing rotary tables by a circle, the number of the medicine placing rotary tables is multiple, and the driving output end of the driving device faces upwards. The sizes of the medicine containing cavities formed in the different medicine containing rotary discs are different, and each medicine containing rotary disc is detachably assembled at the driving output end of the driving device and used for conducting fixed-axis rotation along the central axis of the corresponding medicine containing rotary disc under the driving effect of the driving device. The laser emitting device is located above the medicine containing rotary disc, and the aperture detection device is located above the medicine containing rotary disc. When the osmotic pump controlled release tablets with different sizes and different types are developed, a user can select a proper medicine placing turntable according to the osmotic pump controlled release tablets with different sizes and different types, so that the development requirements of the osmotic pump controlled release tablets are met.

Description

Technical Field

[0001] The present application relates to the field of pharmaceutical technology, and in particular to a laboratory-based oral osmotic pump controlled-release tablet punching inspection system. Background Art

[0002] The osmotic principle can be used to make slow-release oral osmotic pump controlled-release tablets, which can release drugs evenly for a long time in the body. Under normal circumstances, oral osmotic pump controlled-release tablets need to be coated with a semipermeable membrane on the outside of the tablet core of the oral osmotic pump controlled-release tablet, and then a small hole is punched on the semipermeable membrane with a laser. The small hole is the hole for releasing the drug. After the oral osmotic pump controlled-release tablet is taken orally, the water in the body can enter the tablet core of the oral osmotic pump controlled-release tablet through the semipermeable membrane, dissolve the drug or osmotic pressure generator, and generate osmotic pressure, and continuously push out the drug, so it is also called an osmotic pump controlled-release tablet. There are many types of osmotic pump controlled-release tablets, such as single-chamber osmotic pump controlled-release tablets and double-chamber osmotic pump controlled-release tablets. The osmotic pressure generator of the single-chamber osmotic pump controlled-release tablet is mixed with the drug, and there is no need to distinguish the tablets according to the front and back. A small hole is punched on both the front and back of the single-chamber osmotic pump controlled-release tablet, and the drug can be released. The double-chamber osmotic pump controlled-release tablets have a two-layer structure, one layer of which is the drug reservoir, and the other layer is the osmotic pressure generator. The osmotic pressure generator absorbs water and swells, generating a driving force to push the drug out of the small hole. Therefore, for the double-chamber osmotic pump controlled-release tablets, the small hole must be punched on the coating layer of the drug reservoir, otherwise the drug cannot be released.

[0003] At present, pharmaceutical research laboratories and pharmaceutical companies are continuously developing and producing new drug dosage forms of osmotic pump controlled-release tablets. Osmotic pump controlled-release tablets generally require lasers to punch small holes on the tablets for drug release. For this purpose, there are some special laser drilling inspection machines. However, although these laser drilling inspection machines can realize the drilling of osmotic pump controlled-release tablets, they are expensive and have strong targeted application scenarios. They are not suitable for use in the laboratory for the development and research of new drug dosage forms of osmotic pump controlled-release tablets. Both the cost and the wide range of applicable scenarios do not meet the laboratory's research and development needs. Therefore, the field urgently needs to provide a low-cost drilling inspection machine that can meet the laboratory's research and development needs and has a wide range of application scenarios. Summary of the invention

[0004] Based on this, it is necessary to provide a laboratory oral osmotic pump controlled-release tablet punching inspection system to address the above-mentioned technical issues.

[0005] The present application provides a laboratory-based oral osmotic pump controlled-release tablet punching inspection system, the laboratory-based oral osmotic pump controlled-release tablet punching inspection system comprising:

[0006] System main frame;

[0007] A driving device, the driving device is arranged on the main frame of the system, wherein the driving output end of the driving device faces upward;

[0008] A medicine placing turntable, wherein a plurality of medicine placing cavities are provided on the medicine placing turntable, and the plurality of medicine placing cavities are arranged around the central axis of the medicine placing turntable, wherein the number of the medicine placing turntables is set to be multiple, and the sizes of the medicine placing cavities provided on different medicine placing turntables in the plurality of medicine placing turntables are different, and each of the medicine placing turntables is detachably mounted at the driving output end of the driving device, and is used for rotating along the central axis of the medicine placing turntable under the driving action of the driving device;

[0009] A laser emitting device, which is arranged on the main frame of the system, wherein the laser emitting device is located above the medicine placing turntable;

[0010] An aperture detection device is arranged on the main frame of the system, wherein the aperture detection device is located above the medicine placing turntable.

[0011] In one embodiment, the centers of the multiple medicine placement cavities opened in each medicine placement turntable have a first vertical connection line with the central axis of the medicine placement turntable, wherein along the circumferential direction of the medicine placement turntable, the angles of cavity distribution between all adjacent first vertical connection lines are the same;

[0012] The laser emitting device and the aperture detection device both have a second vertical connection line with the central axis of the medicine placing turntable, wherein along the circumferential direction of the medicine placing turntable, the angle between the two second vertical connection lines is the same as the angle of the cavity distribution.

[0013] In one embodiment, the driving device comprises:

[0014] A device base, the device base is arranged on the system main frame, and the device base is provided with an assembly accommodating chamber;

[0015] A driving motor, wherein the driving motor is mounted in the assembly accommodating chamber of the base of the device, wherein the driving output shaft of the driving motor is used to constitute the driving output end of the driving device, each of the medicine placing turntables is provided with a central fixed shaft hole, and each of the medicine placing turntables is detachably mounted on the driving output shaft through the central fixed shaft hole, and the single rotation angle of the driving motor is the same as the angle of the cavity distribution angle, so that the multiple medicine placing cavities opened on the medicine placing turntable are placed in sequence along the circumferential direction of the medicine placing turntable directly below the laser emitting device or the aperture detection device.

[0016] In one embodiment, the driving motor is a stepper motor or a servo motor.

[0017] In one embodiment, the laboratory oral osmotic pump controlled-release tablet punching inspection system comprises:

[0018] A fixed chassis, wherein the fixed chassis is provided with a central assembly shaft hole, wherein the fixed chassis is fixed to the main frame of the system, and the fixed chassis is movably assembled with the driving output shaft of the driving motor through the central assembly shaft hole, the medicine placing turntable is fixedly assembled with the driving output shaft of the driving motor through the central fixed shaft hole, the medicine placing cavity is a through medicine placing through hole, and the bottom surface of the medicine placing turntable is in contact with the top surface of the fixed chassis for covering the medicine placing through hole.

[0019] In one of the embodiments, a medicine dropping through hole is further provided on the fixed chassis, and the medicine dropping through hole is used to communicate with one of the medicine placing through holes during the process of the medicine placing turntable rotating relative to the fixed chassis.

[0020] In one embodiment, the laboratory oral osmotic pump controlled-release tablet punching inspection system comprises:

[0021] A collecting device is provided with a plurality of collecting cavities, and the collecting device is arranged on the main frame of the system, wherein the collecting device is located directly below the medicine dropping hole.

[0022] In one embodiment, the laboratory oral osmotic pump controlled-release tablet punching inspection system comprises:

[0023] Main control computer;

[0024] A control device is connected to the main control computer and is control-connected to the drive device for controlling the drive device to run or stop.

[0025] In one embodiment, the laboratory oral osmotic pump controlled-release tablet punching inspection system comprises:

[0026] A display device is connected to the main control computer, and the main control computer is connected to the laser emitting device and the aperture detection device.

[0027] In one embodiment, the laboratory oral osmotic pump controlled-release tablet punching inspection system comprises:

[0028] A printing device is connected to the main control computer, and the main control computer is connected to the laser emitting device and the aperture detection device.

[0029] In the above-mentioned laboratory-used oral osmotic pump controlled-release tablet punching inspection system, when a new drug dosage form of an osmotic pump controlled-release tablet is developed and produced in the laboratory, the sizes of the osmotic pump controlled-release tablets targeted in various research and development scenarios are all different. Therefore, the existing punching inspection machine cannot adapt to the experiments of many osmotic pump controlled-release tablets of different sizes and types. In order to meet the production needs of the development of many osmotic pump controlled-release tablets of different sizes and types, the laboratory-used oral osmotic pump controlled-release tablet punching inspection system provided by the present application provides a plurality of replaceable drug-placing turntables. Among the plurality of drug-placing turntables provided, the sizes of the drug-placing cavities opened on the different drug-placing turntables are all different, so that each drug-placing turntable can adapt to osmotic pump controlled-release tablets of different sizes and types, and meet the storage of osmotic pump controlled-release tablets of different sizes and types in the drug-placing cavities thereon. Therefore, when developing osmotic pump controlled-release tablets of different sizes and types, the user can select a suitable drug-placing turntable according to the different sizes and types of osmotic pump controlled-release tablets. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 A schematic diagram of the structure of a laboratory oral osmotic pump controlled-release tablet punching inspection system provided in one embodiment of the present application.

[0031] Figure 2 A schematic diagram of a first vertical connection line provided in one embodiment of the present application.

[0032] Figure 3 A schematic diagram of the structure of a laboratory oral osmotic pump controlled-release tablet punching inspection system provided in the second embodiment of the present application.

[0033] Figure 4 A schematic diagram of the structure of a laboratory oral osmotic pump controlled-release tablet punching inspection system provided in the third embodiment of the present application.

[0034] Figure 5 A schematic diagram of the structure of a laboratory oral osmotic pump controlled-release tablet punching inspection system provided in the fourth embodiment of the present application.

[0035] Figure 6 This is a schematic diagram of the structure of a laboratory oral osmotic pump controlled-release tablet punching inspection system provided in the fifth embodiment of the present application.

[0036] Figure Number:

[0037] 100, tablet; 1000, driving device; 2000, medicine placing turntable; 3000, laser emitting device; 4000, aperture detection device; 6000, collecting device; 7000, control device; 8000, display device; 9000, printing device; 2000a, medicine placing cavity; 2000a1, first vertical connecting line; 5000a, medicine dropping hole; 6000a, collecting cavity. DETAILED DESCRIPTION

[0038] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific embodiments disclosed below.

[0039] In the description of the present application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application.

[0040] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of this application, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0041] In this application, unless otherwise clearly specified and limited, if the terms "installed", "connected", "connected", "fixed" and the like appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances.

[0042] In the present application, unless otherwise clearly specified and limited, if there is a description that a first feature is "above" or "below" a second feature, etc., or similar descriptions appear, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0043] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only implementation method.

[0044] See also Figure 1 As shown, the present application is a laboratory-use oral osmotic pump controlled-release tablet punching inspection system, which includes a system main frame, a driving device 1000, a medicine placing turntable 2000, a laser emitting device 3000 and an aperture detection device 4000. Among them, the system main frame is used as an assembly basis for centralized assembly of devices such as the driving device 1000, the medicine placing turntable 2000, the laser emitting device 3000, the aperture detection device 4000 and other auxiliary devices. Therefore, the system main frame can be specifically designed based on the structural characteristics of the driving device 1000, the medicine placing turntable 2000, the laser emitting device 3000 and the aperture detection device 4000 and the convenience of coordination and functionality with other auxiliary devices. Therefore, the present application does not limit the specific structure of the system main frame, but only requires that the system main frame can meet the assembly requirements of devices such as the driving device 1000, the medicine placing turntable 2000, the laser emitting device 3000 and the aperture detection device 4000 and other auxiliary devices. Those skilled in the art can select the material, structure and size of the system main frame according to actual needs, including but not limited to the system main frame in the form of a frame, the system main frame in the form of a shell and other structural forms, which are not limited here.

[0045] The driving device 1000 is arranged on the main frame of the system, wherein the driving output end of the driving device 1000 faces upward. The medicine placing turntable 2000 is provided with a plurality of medicine placing cavities 2000a, which can be used to load the tablets 100, and the plurality of medicine placing cavities 2000a are arranged around the central axis of the medicine placing turntable 2000, wherein the number of the medicine placing turntable 2000 is set to be multiple, and the sizes of the medicine placing cavities 2000a opened on different medicine placing turntables 2000 in the plurality of medicine placing turntables 2000 are all different, and each medicine placing turntable 2000 is detachably mounted on the driving output end of the driving device 1000, therefore, the medicine placing turntable 2000 currently mounted on the driving device 1000 can be rotated along the central axis of the medicine placing turntable 2000 under the driving action of the driving device 1000, thereby driving the tablets 100 to rotate by rotating the fixed axis.

[0046] The laser emitting device 3000 is arranged on the main frame of the system, wherein the laser emitting device 3000 is located above the medicine placing turntable 2000. The laser emitting device 3000 can continuously face up and down with different medicine placing cavities 2000a on the medicine placing turntable 2000 during the fixed-axis rotation of the medicine placing turntable 2000. Therefore, when the tablet 100 in the medicine placing cavity 2000a passes directly under the laser emitting device 3000, the laser emitting device 3000 can apply laser to the tablet 100 currently located directly under it, perform a punching operation on the tablet 100, and leave a hole on the tablet 100, which is a non-through slot hole. The aperture detection device 4000 is arranged on the main frame of the system, wherein the aperture detection device 4000 is located above the medicine placing turntable 2000. The aperture detection device 4000 can continuously face up and down with different medicine placing cavities 2000a on the medicine placing turntable 2000 during the fixed-axis rotation of the medicine placing turntable 2000. Therefore, when the tablet 100 in the medicine placing cavity 2000a passes directly under the aperture detection device 4000, the aperture detection device 4000 can detect the tablet 100 currently located directly under it, and detect whether the size of the hole left on the tablet 100 that has completed the punching operation meets the expected punching requirements.

[0047] When developing and producing new drug dosage forms of osmotic pump controlled-release tablets in the laboratory, the sizes of the osmotic pump controlled-release tablets used in various research and development scenarios are different. Therefore, the existing punching inspection machine cannot adapt to the experiments of many osmotic pump controlled-release tablets of different sizes and types. In order to meet the production needs of the development of many osmotic pump controlled-release tablets of different sizes and types, the laboratory oral osmotic pump controlled-release tablet punching inspection system provided by the present application provides a plurality of replaceable medicine turntables 2000. Among the plurality of medicine turntables 2000 provided, the sizes of the medicine cavities 2000a opened on different medicine turntables 2000 are different, so that each medicine turntable 2000 can adapt to osmotic pump controlled-release tablets of different sizes and types, so that the medicine cavities 2000a thereon can accommodate osmotic pump controlled-release tablets of different sizes and types. Therefore, when developing osmotic pump controlled-release tablets of different sizes and types, the user can select a suitable medicine placing turntable 2000 according to the osmotic pump controlled-release tablets of different sizes and types.

[0048] When replacing, it is only necessary to remove the unmatched medicine placement turntable 2000 from the drive output end of the driving device 1000, and then install the matched medicine placement turntable 2000 on the drive output end of the driving device 1000. At this time, the osmotic pump controlled release tablet to be tested can be loaded into the medicine placement cavity 2000a of the matched medicine placement turntable 2000, and the driving device 1000 is used to drive the medicine placement turntable 2000 to rotate on a fixed axis. For example, if the tablet 100 (osmotic pump controlled release tablet) is a double-chamber osmotic pump controlled tablet, the medicine store to be punched can be facing upward. The shape and size of the medicine placement cavity 2000a on the matched medicine placement turntable 2000 can be customized according to factors such as the diameter size, shape, and thickness of the tablet 100. Among them, the detachable connection between the medicine placement turntable 2000 and the drive output end of the driving device 1000 can be adopted in a variety of ways such as threaded connection, clamping, bonding, etc., which are not limited here. For example, when the medicine placing turntable 2000 is threadedly connected, the unmatched medicine placing turntable 2000 can be unscrewed by the fixing nut when replaced, and the unmatched medicine placing turntable 2000 can be removed, and the matched medicine placing turntable 2000 can be installed, and the matched medicine placing turntable 2000 can be tightened by the fixing nut.

[0049] During the experiment, the main power switch can be turned on to put the laboratory oral osmotic pump controlled release tablet punching inspection system into working condition, adjust the focal length of the laser emitting device 3000 and the aperture detection device 4000, and adjust the light for verification. After all preparations are completed, use the driving device 1000 to drive the medicine placing turntable 2000 to rotate. The laser emitting device 3000 will emit a laser beam according to the set punching time to punch a small hole in the tablet 100. At the same time, a small spark and a wisp of green smoke will appear. As the medicine placing turntable 2000 rotates, the second tablet 100 will also pass by the laser emitting device 3000. The laser emitting device 3000 will emit a laser beam according to the set punching time to punch a small hole in the second tablet 100, and the first punched tablet 100 will rotate to the bottom of the aperture detection device 4000. The aperture detection device 4000 can be used to determine the number of holes that have been punched on the first tablet 100. As the medicine placing turntable 2000 continues to rotate, the third tablet 100 will also pass through the laser emitting device 3000, and the laser emitting device 3000 will emit a beam of laser to punch a small hole in the third tablet 100 according to the set punching time, and the second punched tablet 100 will rotate to just below the aperture detection device 4000, and the aperture detection device 4000 can be used to measure the aperture size of the hole that has been punched on the second tablet 100, and the cycle will continue. As the medicine placing turntable 2000 continues to rotate, the laser emitting device 3000 and the aperture detection device 4000 will continuously perform punching and aperture detection on the passing tablets 100.

[0050] See also Figure 2As shown, in one embodiment, the cavity centers of the multiple medicine placement cavities 2000a opened in each of the medicine placement turntables 2000 have a first vertical connection line 2000a1 with the central axis of the medicine placement turntable 2000, wherein along the circumferential direction of the medicine placement turntable 2000, the angles of cavity distribution angles between all adjacent first vertical connection lines 2000a1 are the same. The first vertical connection line 2000a1 is a virtual line, which can be used to represent the distribution state of the multiple medicine placement cavities 2000a in the medicine placement turntable 2000. At this time, the laser emitting device 3000 and the aperture detection device 4000 both have a second vertical connection line with the central axis of the medicine placement turntable 2000, wherein along the circumferential direction of the medicine placement turntable 2000, the angle between the two second vertical connection lines is the same as the angle of the cavity distribution angle. Therefore, the distribution state of the multiple medicine placing cavities 2000a in the medicine placing turntable 2000 matches the assembly positions of the laser emitting device 3000 and the aperture detection device 4000. This matching state enables the medicine placing turntable 2000 to have a medicine placing cavity 2000a directly below the laser emitting device 3000 and a medicine placing cavity 2000a directly below the aperture detection device 4000 each time the medicine placing turntable 2000 rotates by only one cavity distribution angle.

[0051] Therefore, in one embodiment, when the laser emitting device 3000 punches a small hole on the first tablet 100, if the medicine placing turntable 2000 rotates only one cavity distribution angle each time, when the second tablet 100 is directly below the laser emitting device 3000, the first punched tablet 100 will just rotate to the bottom of the aperture detection device 4000. At this time, when the laser emitting device 3000 punches a hole in the second tablet 100, the aperture detection device 4000 can simultaneously measure the aperture size of the hole punched on the first tablet 100. Similarly, when the third tablet 100 is directly below the laser emitting device 3000, the second punched tablet 100 will also just rotate to the bottom of the aperture detection device 4000, thereby continuously performing the synchronous operation of punching and aperture detection, thereby improving the experimental efficiency.

[0052] Alternatively, in one embodiment, the laser emitting device 3000 may first continuously punch a small hole in multiple tablets 100. When the medicine placing turntable 2000 rotates by an integer multiple of the cavity distribution angle, so that the tablet 100 that has not been punched is directly below the laser emitting device 3000, the punched tablet 100 will just rotate to be directly below the aperture detection device 4000. At this time, when the laser emitting device 3000 punches a hole in the tablet 100 that has not been punched, the aperture detection device 4000 can simultaneously measure the aperture size of the hole that has been punched in the punched tablet 100. Compared with the above embodiment in which the aperture measurement of the tablet 100 is performed immediately after the hole is punched, in this embodiment, the laser emitting device 3000 may first continuously punch a small hole in multiple tablets 100, and then measure the aperture of the punched tablet 100 in turn, and so on.

[0053] In one embodiment, the driving device 1000 includes a device base and a driving motor, the device base is arranged on the main frame of the system, and the device base is provided with an assembly accommodating chamber. The driving motor is installed in the assembly accommodating chamber of the device base, wherein the driving output shaft of the driving motor is used to constitute the driving output end of the driving device 1000, each of the medicine placing turntables 2000 is provided with a central fixed shaft hole, and each of the medicine placing turntables 2000 is detachably mounted on the driving output shaft through the central fixed shaft hole, and the single rotation angle of the driving motor is the same as the angle of the cavity distribution angle, so that the multiple medicine placing cavities 2000a opened on the medicine placing turntable 2000 are sequentially placed directly below the laser emitting device 3000 or the aperture detection device 4000 along the circumferential direction of the medicine placing turntable 2000. In one embodiment, the driving motor is a stepping motor or a servo motor.

[0054] The medicine placement cavity 2000a in the medicine placement turntable 2000 may be a groove structure, or in one embodiment, the laboratory oral osmotic pump controlled release tablet punching inspection system may further include a fixed chassis, the fixed chassis is provided with a central assembly shaft hole, wherein the fixed chassis is fixed to the system main frame, and the fixed chassis is movably assembled with the driving output shaft of the driving motor through the central assembly shaft hole, the medicine placement turntable 2000 is fixedly assembled with the driving output shaft of the driving motor through the central fixed shaft hole, and the medicine placement cavity 2000a is a through-hole for placing medicines.

[0055] At this time, the bottom surface of the medicine placing turntable 2000 is in contact with the top surface of the fixed chassis, but the bottom surface of the medicine placing turntable 2000 and the top surface of the fixed chassis do not restrict the relative rotation of the two, and the top surface of the fixed chassis is only used to block the medicine placing through hole. Therefore, the driving device 1000 can drive the medicine placing turntable 2000 to rotate relative to the fixed chassis. Since the top surface of the fixed chassis blocks the medicine placing through hole, even if the tablet 100 is placed in the medicine placing through hole on the medicine placing turntable 2000, the tablet 100 will not fall due to the blocking of the top surface of the fixed chassis, but will rotate with the rotation of the medicine placing turntable 2000.

[0056] At this time, in one of the embodiments, a medicine dropping hole 5000a may be further opened on the fixed chassis, and the medicine dropping hole 5000a is used to communicate with one of the medicine placing holes during the process of the medicine placing turntable 2000 rotating relative to the fixed chassis. Therefore, when the medicine dropping hole 5000a is connected with one of the medicine placing holes during the process of the medicine placing turntable 2000 rotating relative to the fixed chassis, the connected medicine placing holes are not blocked by the top surface of the fixed chassis, so that the tablets 100 can fall. This design structure can be used to automatically drop the tablets 100 that have been punched. And, refer to Figure 3 As shown, in one embodiment, the laboratory oral osmotic pump controlled-release tablet punching inspection system includes a collecting device 6000, and the collecting device 6000 has a plurality of collecting cavities 6000a. The collecting device 6000 is disposed on the main frame of the system, wherein the collecting device 6000 is located directly below the drug drop hole 5000a, and is used to collect the tablets 100 that have been punched.

[0057] In addition, see Figure 4 As shown, in one embodiment, the laboratory oral osmotic pump controlled release tablet punching inspection system may also include a main control computer (not shown) and a control device 7000, and the control device 7000 may be selectively arranged on the main frame of the system according to the needs, wherein the control device 7000 is connected to the main control computer, and the control device 7000 is control-connected to the drive device 1000, and is used to control the operation and stop of the drive device 1000, so that the drive device 1000 only rotates one cavity distribution angle each time under control. Figure 5As shown, in one embodiment, the laboratory oral osmotic pump controlled release tablet punching inspection system may also include a display device 8000, which can be set on the main frame of the system according to needs, wherein the display device 8000 is connected to the main control computer, and the display control of the display device is implemented by the main control computer. The main control computer is connected to the laser emitting device 3000 and the aperture detection device 4000. Under the control of the main control computer, the display device 8000 can be used to display the power of the laser punching, the time of the punching, the aperture of the tablet 100 punched by the aperture detection device 4000, the test date, the name of the tester and other information. And refer to Figure 6 As shown, in one embodiment, the laboratory oral osmotic pump controlled-release tablet punching inspection system may also include a printing device 9000, and the printing device 9000 can be selectively set on the system main frame according to needs, wherein the printing device 9000 is connected to the main control computer, and the main control computer implements printing control on the display device, and the main control computer is connected to the laser emitting device 3000 and the aperture detection device 4000. Under the control of the main control computer, the laser punching power, the punching time, the aperture of the tablet 100 punched by the aperture detection device 4000, the test date, the name of the tester and other information displayed in the display device 8000 can also be directly printed out.

[0058] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0059] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be construed as limiting the scope of the patent application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent application shall be subject to the attached claims.

Claims

1. A laboratory oral osmotic pump controlled release tablet punching inspection system, characterized in that: The laboratory oral osmotic pump controlled-release tablet punching inspection system comprises: System main frame; A driving device, the driving device is arranged on the main frame of the system, wherein the driving output end of the driving device faces upward; A medicine placing turntable, wherein a plurality of medicine placing cavities are provided on the medicine placing turntable, and the plurality of medicine placing cavities are arranged around the central axis of the medicine placing turntable, wherein the number of the medicine placing turntables is set to be multiple, and the sizes of the medicine placing cavities provided on different medicine placing turntables in the plurality of medicine placing turntables are different, and each of the medicine placing turntables is detachably mounted at the driving output end of the driving device, and is used for rotating along the central axis of the medicine placing turntable under the driving action of the driving device; A laser emitting device, which is arranged on the main frame of the system, wherein the laser emitting device is located above the medicine placing turntable; An aperture detection device, the aperture detection device is arranged on the main frame of the system, wherein the aperture detection device is located above the medicine placing turntable; The cavity centers of the multiple medicine placing cavities opened in each medicine placing turntable have a first vertical connection line with the central axis of the medicine placing turntable, wherein along the circumferential direction of the medicine placing turntable, the angles of cavity distribution between all adjacent first vertical connection lines are the same; the single rotation angle of the medicine placing turntable driven by the driving device is the same as the angle of the cavity distribution angle, so that the multiple medicine placing cavities opened on the medicine placing turntable are placed in sequence along the circumferential direction of the medicine placing turntable directly below the laser emitting device or the aperture detection device.

2. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 1, characterized in that: The laser emitting device and the aperture detection device both have a second vertical connection line with the central axis of the medicine placing turntable, wherein along the circumferential direction of the medicine placing turntable, the angle between the two second vertical connection lines is the same as the angle of the cavity distribution.

3. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 2, characterized in that: The driving device comprises: A device base, the device base is arranged on the system main frame, and the device base is provided with an assembly accommodating chamber; A driving motor, wherein the driving motor is mounted in the assembly accommodating chamber of the base of the device, wherein the driving output shaft of the driving motor is used to constitute the driving output end of the driving device, each of the medicine placing turntables is provided with a central fixed shaft hole, and each of the medicine placing turntables is detachably mounted on the driving output shaft through the central fixed shaft hole, and the single rotation angle of the driving motor is the same as the angle of the cavity distribution angle, so that the multiple medicine placing cavities opened on the medicine placing turntable are placed in sequence along the circumferential direction of the medicine placing turntable directly below the laser emitting device or the aperture detection device.

4. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 3, characterized in that: The driving motor is a stepping motor or a servo motor.

5. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 3, characterized in that: The laboratory oral osmotic pump controlled-release tablet punching inspection system comprises: A fixed chassis, wherein the fixed chassis is provided with a central assembly shaft hole, wherein the fixed chassis is fixed to the main frame of the system, and the fixed chassis is movably assembled with the driving output shaft of the driving motor through the central assembly shaft hole, the medicine placing turntable is fixedly assembled with the driving output shaft of the driving motor through the central fixed shaft hole, the medicine placing cavity is a through medicine placing through hole, and the bottom surface of the medicine placing turntable is in contact with the top surface of the fixed chassis for covering the medicine placing through hole.

6. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 5, characterized in that: The fixed chassis is also provided with a medicine dropping through hole, and the medicine dropping through hole is used to communicate with one of the medicine placing through holes during the process of the medicine placing rotating disk rotating relative to the fixed chassis.

7. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 6, characterized in that: The laboratory oral osmotic pump controlled-release tablet punching inspection system comprises: A collecting device is provided with a plurality of collecting cavities, and the collecting device is arranged on the main frame of the system, wherein the collecting device is located directly below the medicine dropping hole.

8. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 1, characterized in that: The laboratory oral osmotic pump controlled-release tablet punching inspection system comprises: Main control computer; A control device is connected to the main control computer and is control-connected to the drive device for controlling the drive device to run or stop.

9. The laboratory oral osmotic pump controlled-release tablet punching inspection system according to claim 8, characterized in that: The laboratory oral osmotic pump controlled-release tablet punching inspection system comprises: A display device is connected to the main control computer, and the main control computer is connected to the laser emitting device and the aperture detection device.

10. The laboratory oral osmotic pump controlled release tablet punching inspection system according to claim 8, characterized in that: The laboratory oral osmotic pump controlled-release tablet punching inspection system comprises: A printing device is connected to the main control computer, and the main control computer is connected to the laser emitting device and the aperture detection device.

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