Mouse metabolism cage for medical research

Abstract

The utility model discloses a mouse metabolism cage for medical research, which comprises an excrement receiving hopper, and a placing plate is arranged below the excrement receiving hopper; a knocking assembly is arranged on the placing plate and comprises a bottom plate, a control box, a rotating shaft, an eccentric wheel, a fixed block I, a push rod I, a knocking head, a fixed block II and a push rod II; the bottom plate is fixed on the placing plate; the control box is fixed on the bottom plate; the rotating shaft rotates on the control box; the eccentric wheel is fixed on the rotating shaft; the fixed block I is fixed on the right side of the eccentric wheel; the fixed block II is fixed on the left side of the eccentric block; the push rod I is fixed on the right side of the fixed block I; the push rod II is fixed on the left side of the fixed block II; the knocking head is fixed at the right end of the push rod; through cooperation of the knocking assembly and the filtering gauze, the problems that under the condition that existing mouse excrement is granular, the excrement is blocked in filtering holes due to the fact that the filtering holes of a filtering net are small, and the excrement falls off from the filtering net and is mixed with urine due to the fact that the filtering holes are large, and separation of the excrement and the urine is not facilitated are solved.

Description

Technical Field

[0001] The utility model relates to the technical field of metabolic cages for mice and rats, in particular to a metabolic cage for mice used in medical research. Background Art

[0002] In order to better carry out clinical medical applications, medical experiments are conducted in advance to provide experimental data for the clinical application of drugs. Medical research often uses some small animals for pharmaceutical experiments. Among them, mice are often used in scientific research and teaching experiments due to their small size, fast breeding, stable biological characteristics, and easy experimental operation. Generally, in experiments, it is necessary to closely monitor the food intake, water intake, and excrement of mice, and test and record their various indicators. Mice are often fed in metabolic cages to facilitate experimenters to collect various data information.

[0003] Metabolic cages often use filters to filter mouse excrement. Since mouse feces are mostly granular, feces will be blocked in the filter holes if the filter holes are small, and feces will fall from the filter and mix with urine if the filter holes are large, which is not conducive to the separation of feces and urine, and affects the collection of feces and urine data information in the later stage. Utility Model Content

[0004] The embodiment of the present application provides a mouse metabolic cage for medical research, which solves the problem that when the existing mouse feces are in granular form, the filter holes of the filter are small and the feces are blocked in the filter holes, while the feces fall from the filter net and mix with urine, which is not conducive to the separation of feces and urine, due to the cooperation of the knocking component and the filter gauze.

[0005] The embodiment of the present application provides a mouse metabolism cage for medical research, comprising a cage, a placement opening is provided on the front end surface of the cage, a cage door is installed in the placement opening, and the cage door and the cage are hinged by hinges; a connecting block 1 is fixedly connected to the left side of the cage, and a supporting frame 1 is fixedly connected to the left side of the connecting block 1; a connecting block 2 is fixedly connected to the right side of the cage, and a supporting frame 2 is fixedly connected to the right side of the connecting block 2; the supporting frame 1 and the supporting frame 2 are both configured as inverted U-shaped frames;

[0006] A feces receiving hopper is provided between the support frame 1 and the support frame 2, and connecting plates are fixedly connected to the left and right sides of the upper side of the feces receiving hopper, and the connecting plates are respectively fixedly connected to the front and rear sides of the support frame 1 and the front and rear sides of the support frame 2; the feces receiving hopper is located below the cage, and a filter screen is provided inside it, and a layer of filter gauze is detachably laid on the upper side of the filter screen; a placement plate is provided below the feces receiving hopper, and the placement plate is fixedly connected between the support frame 1 and the support frame 2, and a receiving box is placed on the upper side of the placement plate;

[0007] The placement plate is provided with a knocking assembly, which is located on the left side of the receiving box, and the knocking assembly includes a bottom plate, a control box, a rotating shaft, an eccentric wheel, a fixing block 1, a push rod 1, a knocking head, a fixing block 2, and a push rod 2;

[0008] The bottom plate is fixedly connected to the upper side of the placement plate, which is located on the left side of the receiving box; the control box is fixedly connected to the upper side of the bottom plate; the rotating shaft is rotatably connected to the upper side of the control box; the eccentric wheel is fixedly sleeved on the rotating shaft; the fixed block 1 is fixedly connected to the right side of the eccentric wheel, and the fixed block 2 is fixedly connected to the left side of the eccentric block; the push rod 1 is fixedly connected to the right side of the fixed block 1, and the push rod 2 is fixedly connected to the left side of the fixed block 2; the knocking head is fixedly connected to the right end of the push rod 1;

[0009] The outer side of the push rod 1 is sleeved with a limiting cylinder 1, and the bottom side of the limiting cylinder 1 is fixedly connected with a fixing rod 1; the outer side of the push rod 2 is sleeved with a limiting cylinder 2, and the bottom side of the limiting cylinder 2 is fixedly connected with a fixing rod 2.

[0010] Furthermore, two knocking components are provided, and the other knocking component is symmetrically arranged on the placement plate, which is located on the right side of the receiving box.

[0011] Furthermore, the push rod 1 and the limiting cylinder 1, as well as the push rod and the limiting cylinder 2 are respectively slidably connected.

[0012] Furthermore, the bottom side of the first fixing rod is fixedly connected to the upper side of the placement plate, and the bottom side of the second fixing rod is fixedly connected to the upper side of the bottom plate.

[0013] Furthermore, the control box is integrated with a motor, a power supply battery, a controller and a time relay;

[0014] The motor is fixedly placed in the middle of the control box, and its upper output end is fixedly connected to the bottom side of the rotating shaft; the power supply battery is placed in the control box, which is located on the left side of the motor, and the power supply battery is electrically connected to the motor through a wire; the controller is placed in the control box, which is located in the front side of the motor, and the controller is electrically connected to the motor through a wire; the time relay is placed in the control box, which is located on the right side of the controller, and the time relay is electrically connected to the controller through a wire.

[0015] Furthermore, a control switch is installed on the front wall of the control box, which is electrically connected to the power supply battery through a wire; a wire outlet hole is reserved on the left wall of the control box for an external power line of the power supply battery.

[0016] Furthermore, the four sides of the filter are embedded in the inner wall of the feces receiving hopper, and the four sides of the filter are fixedly connected to the inner wall of the feces receiving hopper through spring tubes respectively; the filter is slidably connected to the inner wall of the feces receiving hopper.

[0017] Furthermore, the filter screen is equipped with positioning screws, of which at least 6 are provided and are rotatably connected to the filter screen respectively.

[0018] Furthermore, the knocking head and the filter are located on the same horizontal line, and a rubber sleeve is sleeved on the outer side of the knocking head 46 .

[0019] One or more technical solutions provided in the embodiments of the present application have at least the following technical effects or advantages: water and food are placed in a cage, and then a mouse is placed in the cage, the cage door is closed and locked, the mouse can move around in the cage, and its feces and urine are filtered through the filter screen in the feces receiving hopper, the urine falls into the receiving box, and the feces are left on the filter gauze. After a period of time, the experimenter can observe the amount of feces on the filter gauze. In order to avoid too much mouse feces accumulating in one place, the experimenter connects the control box to the power supply, turns on the power supply battery through the control switch, and makes the motor work. As the working shaft of the motor rotates with the eccentric wheel, the push rod 1 and the push rod 2 move left and right along the limit cylinder 1 and the limit cylinder 2 respectively, so that the knocking head knocks the outer wall of the feces receiving hopper, which can cause the filter screen to shake, so that the granular feces of the mouse shake in a small range on the filter screen to avoid affecting the filtration of urine. When the motor works for a certain period of time, the controller automatically turns it off, and the experimenter can turn on the motor again as needed. The cooperation of the knocking component and the filter gauze solves the problem that when the mouse feces are in granular form, the filter holes of the filter are small and the feces will be blocked in the filter holes, while the feces will fall from the filter and mix with the urine, which is not conducive to the separation of feces and urine. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 Schematic diagram of the mouse metabolic cage structure for this application Figure 1 ;

[0021] Figure 2 Schematic diagram of the mouse metabolic cage structure for this application Figure 2 ;

[0022] Figure 3 This is a schematic diagram of the cage opening structure of the mouse metabolic cage of this application;

[0023] Figure 4 Main view of the mouse metabolic cage for this application;

[0024] Figure 5 Strike component structure diagram for this application;

[0025] Figure 6 This is a schematic diagram of the internal structure of the feces receiving hopper for this application;

[0026] Figure 7 This is an enlarged schematic diagram of the structure of Part A of this application;

[0027] Figure 8 This is a schematic diagram of the filter structure for this application.

[0028] In the figure: 10 cage, 11 connecting block 1, 12 supporting frame 1, 13 connecting block 2, 14 supporting frame 2, 20 feces receiving hopper, 21 connecting plate, 22 filter screen, 23 spring tube, 24 positioning screw, 30 placement plate, 31 receiving box, 40 knocking assembly, 41 bottom plate, 42 control box, 43 eccentric wheel, 44 fixed block 1, 45 limiting cylinder 1, 46 knocking head, 47 push rod 1, 48 fixed rod 1, 49 fixed block 2, 410 limiting cylinder 2, 411 push rod 2, 412 fixed rod 2, 413 rotating shaft. DETAILED DESCRIPTION

[0029] In order to facilitate the understanding of the present invention, the present invention will be described more comprehensively with reference to the relevant drawings. The drawings provide preferred embodiments of the present invention. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present invention more thoroughly and comprehensively understood.

[0030] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are for illustrative purposes only and do not represent the only implementation method.

[0031] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art in the technical field of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0032] Embodiment 1

[0033] See also Figure 1-8 , a mouse metabolic cage for medical research, comprising a cage 10,

[0034] A placement opening is provided on the front end surface of the cage 10, and a cage door is installed in the placement opening. The cage door and the cage 10 are hingedly connected by hinges, and are used to place mice in the cage;

[0035] The left side of the cage 10 is fixedly connected with a connection block 11, and the left side of the connection block 11 is fixedly connected with a support frame 12; the right side of the cage 10 is fixedly connected with a connection block 2 13, and the right side of the connection block 2 13 is fixedly connected with a support frame 2 14; the support frame 12 and the support frame 2 14 are both configured as an inverted U-shaped frame;

[0036] A feces receiving hopper 20 is provided between the support frame 12 and the support frame 2 14, and a connecting plate 21 is fixedly connected to the left and right sides of the upper side of the feces receiving hopper 20, and the connecting plate 21 is fixedly connected to the front and rear sides of the support frame 1 12 and the front and rear sides of the support frame 2 14 respectively; the feces receiving hopper 20 is located below the cage 10, and a filter screen 22 is provided therein, and a layer of filter gauze is detachably laid on the upper side of the filter screen 22; a placement plate 30 is provided below the feces receiving hopper 20, and the placement plate 30 is fixedly connected between the support frame 1 12 and the support frame 2 14, and a receiving box 31 is placed on the upper side of the placement plate 30 (the receiving box 31 can be removed from the placement plate 30);

[0037] A knocking assembly 40 is provided on the placement plate 30, which is located on the left side of the receiving box 31 and is used to knock the outer wall of the feces receiving hopper 20 to make the filter screen shake; the knocking assembly 40 includes a bottom plate 41, a control box 42, a rotating shaft 413, an eccentric wheel 43, a fixing block 1 44, a push rod 1 47, a knocking head 46, a fixing block 2 49, and a push rod 2 411;

[0038] The bottom plate 41 is fixedly connected to the upper side of the placement plate 30, which is located on the left side of the receiving box 31; the control box 42 is fixedly connected to the upper side of the bottom plate 41; the rotating shaft 413 is rotatably connected to the upper side of the control box 42; the eccentric wheel 44 is fixedly sleeved on the rotating shaft 413; the fixed block 1 44 is fixedly connected to the right side of the eccentric wheel 43, and the fixed block 2 49 is fixedly connected to the left side of the eccentric block 43; the push rod 1 47 is fixedly connected to the right side of the fixed block 1 44, and the push rod 2 411 is fixedly connected to the left side of the fixed block 2 49; the knocking head 46 is fixedly connected to the right end of the push rod 1 47;

[0039] The outer side of the push rod 1 47 is sleeved with a limiting cylinder 1 45, and the bottom side of the limiting cylinder 1 45 is fixedly connected with a fixing rod 1 48; the outer side of the push rod 2 411 is sleeved with a limiting cylinder 2 410, and the bottom side of the limiting cylinder 2 410 is fixedly connected with a fixing rod 2 412.

[0040] Two knocking components 40 are provided, and the other knocking component 40 is symmetrically arranged on the placement plate 30 and is located on the right side of the receiving box 31 .

[0041] The push rod 1 47 and the limiting cylinder 1 45 , and the push rod 411 and the limiting cylinder 2 410 are respectively slidably connected.

[0042] The bottom side of the fixing rod 1 48 is fixedly connected to the upper side of the placement plate 30 , and the bottom side of the fixing rod 2 412 is fixedly connected to the upper side of the bottom plate 41 .

[0043] The control box 42 is integrated with a motor, a power supply battery, a controller and a time relay;

[0044] The motor is fixedly placed in the middle of the control box 42, and its upper output end is fixedly connected to the bottom side of the rotating shaft 413, which is used to provide power for the rotating shaft 413 to rotate; the power supply battery is placed in the control box 42, which is located on the left side of the motor, and the power supply battery is electrically connected to the motor through a wire; the controller is placed in the control box 42, which is located in front of the motor, and the controller is electrically connected to the motor through a wire; the time relay is placed in the control box 42, which is located on the right side of the controller, and the time relay is electrically connected to the controller through a wire.

[0045] A control switch is mounted on the front wall of the control box 42, and is electrically connected to the power supply battery through a wire;

[0046] A wire outlet hole is reserved on the left wall of the control box 42 for connecting an external power line of the power supply battery.

[0047] The four sides of the filter screen 22 are embedded in the inner wall of the feces receiving hopper 20, and the four sides of the filter screen 22 are fixedly connected to the inner wall of the feces receiving hopper 20 through spring tubes 23. The filter screen 22 can be shaken by knocking the outer walls on the left and right sides of the feces receiving hopper 20 with a knocking head 46, so that the granular feces of the mice will shake in a small range on the filter screen 22 to avoid affecting the filtration of urine (it should be noted that the filter screen 22 is embedded in the inner wall of the feces receiving hopper 20, that is, the inner walls of the four sides of the feces receiving hopper 20 are provided with chutes, and the filter screen 22 is slidably installed in the chutes, and there is no gap between the filter screen 22 and the chutes to avoid the granular feces of the mice rolling into the chutes when rolling on the filter screen 22).

[0048] The knocking head 46 and the filter screen 22 are located on the same horizontal line, and a rubber sleeve is sleeved on the outer side of the knocking head 46 .

[0049] The filter screen 22 is equipped with positioning screws 24, of which at least 6 are provided, which are rotatably connected to the filter screen 22 and are used to fix the filter gauze (it should be noted that through holes are provided on the upper and lower sides of the filter gauze according to the positions of the positioning screws 24. After the positioning screws 24 are unscrewed from the filter screen 22, the filter gauze is spread on the filter screen 22, and then the positioning screws 24 are installed. The filter gauze is fixed to the filter screen 22 by the cooperation of the nut on the positioning screw 24, thereby achieving the separation of mouse feces and urine, and also facilitating the later disassembly and assembly of the filter gauze to collect mouse feces).

[0050] Since there is a certain distance between the feces hopper 20 and the cage 10, in order to prevent the mouse feces or urine from spilling outside the feces hopper 20, a transparent plastic hose can be put on the outside of the cage 10, and the bottom side of the plastic hose is connected to the upper side of the feces hopper 20 (the upper and lower ends of the plastic hose are not sealed).

[0051] It should be noted that an opening and closing door may be left at the front end or rear end of the feces receiving hopper 20 to facilitate the removal of the filter gauze at a later stage;

[0052] The excrement receiving hopper 20 can be made of thin steel plates.

[0053] In actual operation of the embodiment of the present application, water and food are put into the cage 10, and then mice are put into the cage 10 and the cage door is closed and locked. The mice can move in the cage 10, and their feces and urine are filtered through the filter screen 22 in the feces receiving hopper 20, and the urine falls into the receiving box 31. The feces are left on the filter gauze. After a period of time, the experimenter can observe the amount of feces on the filter gauze. In order to avoid too much accumulation of mouse feces in one place, the experimenter connects the control box 42 to the power supply and turns on the power supply through the control switch. The battery makes the motor work, and as the working shaft 413 of the motor rotates with the eccentric wheel 43, the push rod 1 47 and the push rod 2 411 move left and right along the limit cylinder 1 45 and the limit cylinder 2 410 respectively, so that the knocking head 46 knocks the outer wall of the feces receiving hopper 20, which can make the filter screen 22 shake, so that the granular feces of the mice shake in a small range on the filter screen 22 to avoid affecting the filtration of urine. When the motor works for a certain period of time, the controller automatically turns it off, and the experimenter can turn on the motor again as needed.

[0054] The technical solution in the above-mentioned embodiment of the present application has at least the following technical effects or advantages: through the cooperation of the knocking component and the filter gauze, the problem that when the existing mouse feces are granular, the filter holes of the filter screen are small and the feces are blocked in the filter holes, and the feces fall from the filter screen and mix with urine, which is not conducive to the separation of feces and urine, is solved.

[0055] The above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. For those skilled in the art, the utility model may have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A mouse metabolic cage for medical research, comprising a cage, characterized in that: The front end surface of the cage is provided with a placement opening, a cage door is installed in the placement opening, and the cage door and the cage are hinged by hinges; a connection block 1 is fixedly connected to the left side of the cage, and a support frame 1 is fixedly connected to the left side of the connection block 1; a connection block 2 is fixedly connected to the right side of the cage, and a support frame 2 is fixedly connected to the right side of the connection block 2; the support frame 1 and the support frame 2 are both configured as inverted U-shaped frames; A feces receiving hopper is provided between the support frame 1 and the support frame 2, and connecting plates are fixedly connected to the left and right sides of the upper side of the feces receiving hopper, and the connecting plates are respectively fixedly connected to the front and rear sides of the support frame 1 and the front and rear sides of the support frame 2; the feces receiving hopper is located below the cage, and a filter screen is provided inside it, and a layer of filter gauze is detachably laid on the upper side of the filter screen; a placement plate is provided below the feces receiving hopper, and the placement plate is fixedly connected between the support frame 1 and the support frame 2, and a receiving box is placed on the upper side of the placement plate; The placement plate is provided with a knocking assembly, which is located on the left side of the receiving box, and the knocking assembly includes a bottom plate, a control box, a rotating shaft, an eccentric wheel, a fixing block 1, a push rod 1, a knocking head, a fixing block 2, and a push rod 2; The bottom plate is fixedly connected to the upper side of the placement plate, which is located on the left side of the receiving box; the control box is fixedly connected to the upper side of the bottom plate; the rotating shaft is rotatably connected to the upper side of the control box; the eccentric wheel is fixedly sleeved on the rotating shaft; the fixed block 1 is fixedly connected to the right side of the eccentric wheel, and the fixed block 2 is fixedly connected to the left side of the eccentric block; the push rod 1 is fixedly connected to the right side of the fixed block 1, and the push rod 2 is fixedly connected to the left side of the fixed block 2; the knocking head is fixedly connected to the right end of the push rod 1; The outer side of the push rod 1 is sleeved with a limiting cylinder 1, and the bottom side of the limiting cylinder 1 is fixedly connected with a fixing rod 1; the outer side of the push rod 2 is sleeved with a limiting cylinder 2, and the bottom side of the limiting cylinder 2 is fixedly connected with a fixing rod 2.

2. A mouse metabolic cage for medical research as claimed in claim 1, characterized in that: The knocking components are provided with two, and the other knocking component is symmetrically arranged on the placement plate and is located on the right side of the receiving box.

3. A mouse metabolic cage for medical research as claimed in claim 1, characterized in that: The push rod 1 and the limiting cylinder 1, as well as the push rod and the limiting cylinder 2 are respectively slidably connected.

4. A mouse metabolic cage for medical research as claimed in claim 1, characterized in that: The bottom side of the first fixing rod is fixedly connected to the upper side of the placement plate, and the bottom side of the second fixing rod is fixedly connected to the upper side of the bottom plate.

5. A mouse metabolic cage for medical research as claimed in claim 1, characterized in that: The control box is integrated with a motor, a power supply battery, a controller and a time relay; The motor is fixedly placed in the middle of the control box, and its upper output end is fixedly connected to the bottom side of the rotating shaft; the power supply battery is placed in the control box, which is located on the left side of the motor, and the power supply battery is electrically connected to the motor through a wire; the controller is placed in the control box, which is located in the front side of the motor, and the controller is electrically connected to the motor through a wire; the time relay is placed in the control box, which is located on the right side of the controller, and the time relay is electrically connected to the controller through a wire.

6. A mouse metabolic cage for medical research as claimed in claim 5, characterized in that: A control switch is mounted on the front wall of the control box and is electrically connected to the power supply battery via a wire; a wire outlet hole is reserved on the left wall of the control box for connecting an external power line to the power supply battery.

7. A mouse metabolic cage for medical research as claimed in claim 1, characterized in that: The four sides of the filter screen are embedded in the inner wall of the feces receiving hopper, and the four sides of the filter screen are fixedly connected to the inner wall of the feces receiving hopper through spring tubes respectively; the filter screen is slidably connected to the inner wall of the feces receiving hopper.

8. A mouse metabolic cage for medical research as claimed in claim 7, characterized in that: The filter screen is equipped with positioning screws, at least 6 of which are rotatably connected to the filter screen respectively.

9. A mouse metabolic cage for medical research as claimed in claim 1, characterized in that: The knocking head and the filter are located on the same horizontal line, and a rubber sleeve is sleeved on the outer side of the knocking head.

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