Chip sequencer and chip motion platform

By introducing a rotation adjustment component on the chip movement platform, the inaccuracy of taking pictures caused by the inconsistency of the length direction of the chip runner and the movement direction in the prior art is solved, and higher detection accuracy is achieved.

CN222829685UActive Publication Date: 2025-05-06GUANGDONG RUNPENG BIOLOGICAL TECH CO LTD +1
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Patent Information

Application Number
CN202420560253.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-21
Publication Date
2025-05-06
Estimated Expiration
2034-03-21

AI Technical Summary

Technical Problem

The chip movement platform of existing sequencers cannot be adjusted, resulting in deviations in the length direction of the chip runner relative to the movement direction, which in turn leads to inaccurate photography and inaccurate detection.

Method used

A chip movement platform is designed, including a rotation adjustment component, by adjusting the rotation angle of the carrier platform relative to the mobile station, ensuring that the length direction of the chip flow channel is parallel to the movement direction of the moving platform, thereby achieving accurate shooting.

Benefits of technology

Through the use of the rotation adjustment assembly, installation errors are eliminated, ensuring accurate shooting of the chip runner during movement, and improving detection accuracy.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a chip sequencer and a chip motion platform, the chip motion platform comprises a fixed table, a mobile table, a bearing table, a mobile driving member and a rotation adjusting assembly, the rotation adjusting assembly is connected with the bearing table, and the rotation adjusting assembly is used for adjusting the rotation angle of the bearing table relative to the mobile table. As the rotation angle of the bearing table relative to the moving table can be adjusted by the rotation adjusting assembly, after the bearing table is mounted on the moving table, the length direction of the flow channel of the chip on the bearing table can be adjusted to be consistent with the first moving direction of the bearing table through the rotation adjusting assembly, so that the flow channel of the chip can move along the first direction for photographing; the optical system can sequentially shoot along the length direction of the flow channel, the shooting area is always located in the flow channel, the shooting area does not shift to the outer side of the flow channel, the flow channel can be accurately shot, and the detection accuracy is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of biochip sequencing, in particular to a chip sequencer and a chip motion platform. Background Art

[0002] The sequencer includes a chip stage, which is used to fix the chip and drive the chip to move so as to take pictures of the chip.

[0003] The chip motion platform of most existing sequencers cannot be adjusted, and there are installation errors in the chip motion platform. When taking pictures of the chip on the chip platform, there is a tendency for the length direction of the chip flow channel to deviate from the direction of movement, resulting in misalignment of the chip flow when taking pictures. The area outside the flow channel will be photographed instead of the target flow channel, which in turn leads to inaccurate detection. Utility Model Content

[0004] The present application provides a chip sequencer and a chip motion platform to solve the problem of inaccurate photography during chip movement.

[0005] In one embodiment, a chip sequencer is provided, comprising:

[0006] A chip motion platform, comprising a fixed platform, a mobile platform, a carrier platform, a mobile driving member and a rotation adjustment component, wherein the mobile platform is movable along a first direction and is arranged on the fixed platform, the carrier platform is arranged on the mobile platform, the carrier platform is used to fix a carrier chip, the mobile driving member is connected to the mobile platform, the mobile driving member is used to drive the mobile platform and the carrier platform to move along the first direction, the rotation adjustment component is connected to the carrier platform, and the rotation adjustment component is used to adjust the carrier platform to rotate relative to the mobile platform, so as to adjust the length direction of the flow channel of the chip on the carrier platform to be parallel to the first direction;

[0007] a fluid path system connected to the flow channel of the chip on the carrier and used to inject samples and / or reagents into the flow channel of the chip; and

[0008] The optical system is arranged above the carrier platform and is used to take pictures and images of the flow channel of the chip on the carrier platform.

[0009] In one embodiment, the rotation adjustment assembly includes an adjusting member, which can move along a second direction. The adjusting member is connected to a first side surface of the supporting platform. The second direction is located in the same plane as the first direction and is perpendicular to the first direction. The adjusting member moves along the second direction to drive the supporting platform to rotate.

[0010] In one embodiment, the rotation adjustment assembly further includes an elastic member, the elastic member abuts against a second side surface of the support platform, the second side surface is a surface facing away from the first side surface, and the elastic member is used to eliminate a reverse clearance of the rotation of the support platform.

[0011] In one embodiment, the adjusting member and the elastic member are arranged opposite to each other.

[0012] In one embodiment, the rotation adjustment assembly further includes a mounting member, the mounting member is disposed on the moving platform, and the adjustment member is disposed on the mounting member.

[0013] In one embodiment, the rotation adjustment assembly further includes a locking member, and the locking member is used to lock and fix the supporting platform to the fixing platform.

[0014] In one embodiment, the supporting platform is rotatably connected to the moving platform via a rotating shaft, and the adjusting member is used to adjust the supporting platform to rotate around the rotating shaft.

[0015] In one embodiment, a first bearing platform and a second bearing platform are provided on the movable platform, the first bearing platform and the second bearing platform are respectively provided with an adjusting member, and the first bearing platform and the second bearing platform correspond to the same elastic member.

[0016] In one embodiment, the elastic member is squeezed between the first bearing platform and the second bearing platform, one end of the elastic member is connected to the first bearing platform, and the other end of the elastic member is connected to the second bearing platform.

[0017] In one embodiment, a chip motion platform is provided, comprising:

[0018] Fixed table;

[0019] A mobile platform, the mobile platform is movable along a first direction and is disposed on the fixed platform;

[0020] A carrier platform, which is disposed on the mobile platform and is used to fix the carrier chip;

[0021] a moving driving member, the moving driving member being connected to the moving platform and being used for driving the moving platform and the carrying platform to move along the first direction; and

[0022] A rotation adjustment component is connected to the carrier platform, and is used to adjust the carrier platform to rotate relative to the moving platform to adjust the length direction of the flow channel of the chip on the carrier platform to be parallel to the first direction.

[0023] In one embodiment, a first supporting platform and a second supporting platform are provided on the movable platform, the rotation adjustment assembly includes an adjusting member and an elastic member, the first supporting platform and the second supporting platform are respectively provided with an adjusting member, and the first supporting platform and the second supporting platform correspond to the same elastic member.

[0024] According to the chip sequencer and chip motion platform of the above-mentioned embodiments, since a rotation adjustment component is provided on the chip motion platform, the rotation adjustment component can adjust the rotation angle of the carrier platform relative to the mobile platform. After the carrier platform is installed on the mobile platform, the rotation adjustment component can be used to adjust the length direction of the flow channel of the chip on the carrier platform to be consistent with the first direction of movement of the carrier platform, so that when the flow channel of the chip moves along the first direction to take pictures, the optical system can take pictures in sequence along the length direction of the flow channel, and the shooting area is always located in the flow channel, and the shooting area will not be offset to the outside of the flow channel, so that the flow channel can be accurately photographed, thereby improving the accuracy of detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 A schematic diagram of the structure of a chip motion platform in an embodiment;

[0026] Figure 2 A schematic diagram of the structure of a chip motion platform in an embodiment;

[0027] Figure 3 A partial exploded view of a chip motion platform in an embodiment;

[0028] The reference numerals are as follows:

[0029] 1-fixed platform, 11-first track, 12-second track, 2-movable platform, 3-carrying platform, 3a-first carrying platform, 3b-second carrying platform, 31-rotating shaft, 32-mounting groove, 4-rotation adjustment component, 41-mounting part, 42-adjusting part, 43-elastic part, 44-locking part, 5-chip, 51-flow channel. DETAILED DESCRIPTION

[0030] The present invention is further described in detail below by specific embodiments in conjunction with the accompanying drawings. Wherein similar elements in different embodiments adopt associated similar element numbers. In the following embodiments, many detailed descriptions are intended to enable the present application to be better understood. However, those skilled in the art can easily recognize that some of the features can be omitted in different situations, or can be replaced by other elements, materials, and methods. In some cases, some operations related to the present application are not shown or described in the specification, in order to avoid the core part of the present application being overwhelmed by too much description, and for those skilled in the art, it is not necessary to describe these related operations in detail, and they can fully understand the related operations based on the description in the specification and the general technical knowledge in the art.

[0031] In addition, the features, operations or characteristics described in the specification can be combined in any appropriate manner to form various implementations. At the same time, the steps or actions in the method description can also be interchanged or adjusted in a manner that is obvious to those skilled in the art. Therefore, the various sequences in the specification and the drawings are only for the purpose of clearly describing a certain embodiment and are not meant to be a required sequence, unless otherwise specified that a certain sequence must be followed.

[0032] The serial numbers of the components in this document, such as "first", "second", etc., are only used to distinguish the objects described and do not have any order or technical meaning. The "connection" and "coupling" mentioned in this application, unless otherwise specified, include direct and indirect connections (couplings).

[0033] At present, sequencers can meet the detection requirements of low chip utilization area, that is, they mainly take pictures of the middle part of the chip. However, when it is necessary to improve the area utilization of the chip to increase the detection throughput and reduce the detection cost, it is necessary to take pictures of most of the chip area, and some of the pictures are very close to the edge of the flow channel. At this time, if the length direction of the chip flow channel is not parallel to the moving direction of the chip motion platform, when taking pictures of the edge area of ​​the flow channel, the photographed area may be separated from the flow channel and photographed outside the flow channel, or the edge area of ​​the flow channel may not be photographed, resulting in inaccurate detection.

[0034] The present application proposes a new chip motion platform, which can be rotated and adjusted. The moving direction of the chip motion platform can be adjusted to be parallel to the length direction of the chip flow channel to eliminate installation errors and ensure the accuracy of photography; at the same time, it can also reduce the difficulty of installing the chip motion platform.

[0035] Please refer to Figures 1 to 3In one embodiment, a chip motion platform is provided, and the chip motion platform is used to carry the biochip 5 and drive the chip 5 to move so as to take pictures of the objects to be tested in multiple channels in the chip 5 in sequence. The chip motion platform has a rotation adjustment function, and the rotation adjustment function can adjust the direction of the channel of the chip 5 so that the length direction of the channel of the chip 5 is parallel to a movement direction of the chip motion platform, and then the chip motion platform can drive the chip 5 to move along the length direction of its channel to take pictures of the objects to be tested in the channel in sequence. It should be noted that the rotation adjustment function of the chip motion platform is performed during the installation process or maintenance process, and the rotation adjustment function is used to eliminate installation errors. After the rotation adjustment of the chip motion platform, it is fixed and locked to ensure the stability of the position of the chip 5 on the chip motion platform; in other words, the rotation adjustment function of the chip motion platform is not performed during the detection process.

[0036] The chip 5 is a flat plate structure, and the top surface of the chip 5 has multiple parallel flow channels 51. One end of the chip 5 is provided with an inlet, and the other end is provided with an outlet. Each flow channel 51 can be provided with an inlet and an outlet respectively, and multiple flow channels 51 can also share an inlet or an outlet. The flow channel 51 is used to provide a place for the reaction or incubation of the object to be tested. For example, in the gene sequencing process, the flow channel 51 provides a place for the reaction of biological samples and reagents, and the reactants of the biological samples and reagents are the objects to be tested. The upper end of the flow channel 51 is covered with a transparent cover plate, and the setting of the transparent cover plate allows the optical system located above to take pictures of the object to be tested in the flow channel 51.

[0037] The chip motion platform mainly includes a fixed platform 1, a moving platform 2, a carrier platform 3, a moving drive member (not shown in the figure) and a rotation adjustment component 4. The fixed platform 1 can be a part of the frame of the chip sequencer, or a platform installed on the frame. The top surface of the fixed platform 1 is a plane, and a first track 11 is provided on the fixed platform 1. The first track 11 is extended along a first direction, that is, the length direction of the first track 11 is parallel to the first direction, and the first direction is Figure 2 The fixed platform 1 may be provided with two parallel first rails 11 to improve the stability of sliding.

[0038] The mobile platform 2 can be a flat plate structure, and the mobile platform 2 is installed on the first track 11. The lower end of the mobile platform 2 can be provided with a slider or a slide groove adapted to the first track 11. The lower end of the mobile platform 2 is slidably connected to the first track 11 through the slider or the slide groove. The mobile platform 2 can slide along the first track 11 relative to the fixed platform 1, that is, the mobile platform 2 can slide along the first direction relative to the fixed platform 1.

[0039] The mobile driving member is installed on the mobile platform 2. The mobile driving member can be a driving structure such as a cylinder or a linear motor. The output end of the mobile driving member is connected to the mobile platform 2. The mobile driving member is used to drive the mobile platform 2 to slide relative to the fixed platform 1 along the first direction.

[0040] In one embodiment, the mobile platform 2 can also move relative to the fixed platform 1 along a second direction, the second direction is located in the same plane as the first direction, and the first direction is perpendicular to the second direction. Figure 1 The moving platform 2 can move relative to the second direction, that is, the chip moving platform can also drive the chip 5 to move along the second direction, so that during the photographing process, the chip moving platform can also drive the chip 5 to switch different channels 51 along the second direction for photographing, and switch different width directions of the same channel 51 for photographing, so as to realize the sequential photographing and detection of multiple channels 51 on the chip 5. The first track 11 and the second track 12 respectively correspond to movable driving members, one movable driving member is used to drive the moving platform 2 to move along the first direction, and the other movable driving member is used to drive the moving platform 2 to move along the second direction.

[0041] The second track 12 is installed on the fixed platform 1, and a track frame is installed on the second track 12. The first track 11 is installed on the track frame. The second track 12 is arranged along the second direction. Figure 2 In the X-axis direction. That is, the fixed platform 1, the second track 12, the track frame, the first track 11 and the movable platform 2 are installed in sequence from bottom to top. Of course, the positions of the first track 11 and the second track 12 can be interchanged. The first track 11 is installed on the fixed platform 1, and the second track 12 is installed on the track frame. The movable platform 2 can also be moved in the first direction and the second direction.

[0042] In one embodiment, the chip motion platform may also include only the first track 11 , so as to realize photographic detection of a single flow channel 51 on the chip 5 .

[0043] In one embodiment, the carrier 3 can be rotatably mounted on the mobile platform 2, and the middle lower end of the carrier 3 can be rotatably connected to the mobile platform 2 by a rotating shaft 31. The carrier 3 can also be rotatably connected to the mobile platform 2 by a connecting piece of a columnar or tubular structure. The rotating shaft 31 is perpendicular to the plane where the first direction and the second direction are located, so that the carrier 3 can rotate in a plane parallel to the plane where the first direction and the second direction are located. The top surface of the carrier 3 has a mounting groove 32, and the chip 5 is installed in the mounting groove 32. The mounting groove 32 can position and install the chip 5. The flow channel 51 of the chip 5 located on the carrier 3 is arranged parallel to the first direction. If the flow channel 51 of the chip 5 is not parallel to the first direction during the installation process, the flow channel 51 of the chip 5 can be adjusted to be parallel to the first direction by adjusting the carrier 3 to rotate relative to the mobile platform 2.

[0044] The rotation adjustment component 4 is installed on the mobile platform 2, and the rotation adjustment component 4 is connected to the supporting platform 3. The rotation adjustment component 4 can be fixedly connected and abutted with the supporting platform 3. The rotation adjustment component 4 is used to drive the supporting platform 3 to rotate relative to the mobile platform 2 to adjust the rotation angle of the supporting platform 3 relative to the mobile platform 2.

[0045] The rotation adjustment component 4 may include a mounting member 41 and an adjusting member 42. The mounting member 41 may be a structure such as a fixed frame. The mounting member 41 is fixed on the movable platform 2. The adjusting member 42 may be movably mounted on the mounting member 41. The adjusting member 42 may move linearly along the second direction. One end of the adjusting member 42 abuts against or is fixedly connected to the side surface of the supporting platform 3. The connection point between the adjusting member 42 and the supporting platform 3 is at an eccentric position of the supporting platform 3, so that the adjusting member 42 can drive the supporting platform 3 to rotate relative to the movable platform 2 during the movement of the adjusting member 42 along the second direction.

[0046] In one embodiment, the rotation adjustment component 4 may not include the mounting member 41. A raised mounting structure is provided on the mobile platform 2. The adjustment member 42 can be movably mounted on the mounting structure of the mobile platform 2. The installation of the adjustment member 42 and the rotation adjustment of the support platform 3 can also be realized.

[0047] In one embodiment, the rotation adjustment component 4 may further include an elastic member 43, and the elastic member 43 is connected to the support platform 3. The support platform 3 includes a first side surface and a second side surface that are opposite and parallel to each other, the adjustment member 42 is connected to the first side surface of the support platform 3, the elastic member 43 is connected to the second side surface of the support platform 3, and the adjustment member 42 and the elastic member 43 are at the same end of the support platform 3, so that the adjustment member 42 and the elastic member 43 can drive the support platform 3 to rotate in opposite directions, and the elastic member 43 is used to adjust the reverse clearance of the rotation of the support platform 3 to achieve adjustment angle compensation for the adjustment member 42 and improve the adjustment accuracy. For example, the adjustment member 42 can be used to adjust and drive the support platform 3 to rotate clockwise, and the elastic member 43 can be used to adjust the support platform 3 to rotate counterclockwise, wherein clockwise and counterclockwise are the rotation directions of the support platform 3 when viewed from above. Of course, the positions of the adjusting member 42 and the elastic member 43 can be interchanged. The adjusting member 42 is connected to the second side of the carrier 3, and the elastic member 43 is connected to the first side of the carrier 3. The adjusting member 42 can be used to adjust the counterclockwise rotation of the carrier 3, and the elastic member 43 can be used to adjust the clockwise rotation of the carrier 3. The adjusting member 42 belongs to active drive adjustment, and the elastic member 43 belongs to passive drive adjustment. When the adjusting member 42 actively applies a driving force to the carrier 3, the elastic member 43 is forced to compress. When the adjusting member 42 withdraws the active driving force, the elastic member 43 will output a passive driving force to the carrier 3. The combination of the adjusting member 42 and the elastic member 43 can realize the adjustment of the rotation of the carrier 3 in two different directions. No matter whether the flow channel 51 of the chip 5 on the carrier 3 is biased to the left or right relative to the first direction, it can be adjusted to be parallel by the adjusting member 42 and the elastic member 43.

[0048] The adjusting member 42 may be a structure such as a screw, the mounting member 41 is provided with a threaded hole, the screw is installed in the threaded hole, the screw is arranged to move along the second direction, and one end of the screw abuts against the first side surface of the supporting platform 3. The elastic member 43 may be an elastic structure such as a spring, and the spring is always in a compressed state, so that the spring can always provide pressure to the supporting platform 3. The elastic member 43 can not only realize the counterclockwise rotation of the driving platform 3, but also serve as a driving compensation for the adjusting member 42, which can improve the precision of the driving rotation of the adjusting member 42 and position the supporting platform 3 at a more accurate position.

[0049] In one embodiment, the rotation adjustment component 4 may also not include the elastic member 43. The adjustment member 42 has a threaded rod with an external thread, and the support platform 3 is provided with a threaded hole. The threaded rod is connected to the threaded hole of the support platform 3. The adjustment member 42 can drive the support platform 3 to rotate in different directions by forward and reverse rotation, that is, the length direction of the flow channel 51 of the chip 5 on the support platform 3 can be adjusted to be parallel to the first direction through the adjustment member 42.

[0050] In one embodiment, two carriers 3 may be provided on the mobile platform 2, and the mobile platform 2 may simultaneously drive the two carriers 3 to move in the first direction and the second direction at the same time. A first carrier 3a and a second carrier 3b are provided on the carrier 3, and the first carrier 3a and the second carrier 3b are arranged side by side. The first carrier 3a and the second carrier 3b are respectively used to carry and fix a chip 5, and the flow channels 51 of the chips 5 on the first carrier 3a and the second carrier 3b are arranged in parallel.

[0051] The first carrier platform 3a and the second carrier platform 3b are respectively provided with a rotation adjustment component 4, that is, the first carrier platform 3a and the second carrier platform 3b can be rotationally adjusted respectively. The first side of the first carrier platform 3a and the first side of the second carrier platform 3b are arranged in parallel and opposite to each other, and the second side of the first carrier platform 3a and the second side of the second carrier platform 3b are arranged face to face and in parallel. The first carrier platform 3a and the second carrier platform 3b can be adjusted by two adjustment members 42 and an elastic member 43. The first carrier platform 3a and the second carrier platform 3b are respectively provided with an adjustment member 42, and the first carrier platform 3a and the second carrier platform 3b share an elastic member 43, and the elastic member 43 is located between the second side of the first carrier platform 3a and the second side of the second carrier platform 3b. Since the first carrier platform 3a and the second carrier platform 3b can be staggered and adjusted respectively, that is, the two are not adjusted at the same time, the elastic member 43 located at the first carrier platform 3a and the second carrier platform 3b will not affect the position accuracy of the other when adjusting one of them. Two adjusting members 42 and one elastic member 43 are located at the same end of the first bearing platform 3a and the second bearing platform 3b, and the two adjusting members 42 and one elastic member 43 are aligned on a straight line, and the straight line is parallel to the second direction. One adjusting member 42 is used to adjust the first bearing platform 3a to rotate clockwise, and the elastic member 43 is used to adjust the first bearing platform 3a to rotate counterclockwise; the other adjusting member 42 is used to adjust the second bearing platform 3b to rotate counterclockwise, and the elastic member 43 is also used to adjust the second bearing platform 3b to rotate clockwise.

[0052] In one embodiment, a supporting platform 3 may also be set on the mobile platform 2, and the elastic member 43 may be installed on the mobile platform 2, one end of the elastic member 43 is fixed on the mobile platform 2, and the other end of the elastic member 43 is connected to the supporting platform 3, or a mounting member is provided on the mobile platform 2 for mounting the elastic member 43, both of which can realize the connection between the elastic member 43 and the second side of the supporting platform 3.

[0053] In one embodiment, the rotation adjustment component 4 may also include a locking member 44. The locking member 44 may be a locking screw or a locking pin. A mounting hole may be provided on the support platform 3. The locking member 44 is installed in the mounting hole of the support platform 3. The mounting hole may be an arc-shaped hole. A threaded hole perpendicular to the mobile platform 2 is provided on the surface of the mobile platform 2 facing the support platform. The end of the locking member 44 is connected to the threaded hole of the mobile platform 2. When the support platform 3 needs to be adjusted, the locking member 44 is loosened and separated from the mobile platform 2 so that the support platform 3 can rotate relative to the mobile platform 2. When the adjustment is completed, the locking member 44 is locked and connected to the mobile platform 2 to fix the position relationship of the support platform 3 relative to the mobile platform 2 to maintain the precise position of the support platform 3 after adjustment. Among them, the arc-shaped hole of the support platform 3 can prevent the support platform 3 from rotating relative to the locking member 44 during the rotation adjustment process. Of course, the locking member 44 can also be installed on the movable platform 2 and locked with the supporting platform 3, that is, an arc hole is provided on the movable platform 2, and a threaded hole facing the movable platform 2 is provided on the supporting platform 3, so that the supporting platform 3 can be locked and unlocked relative to the movable platform 2.

[0054] In one embodiment, the locking member 44 can also be a clamping member or other structure, wherein the clamping member has an upper clamping jaw and a lower clamping jaw that can move relatively. The locking member 44 can clamp and fix the movable platform 2 and the supporting platform 3 in the up and down directions through the upper clamping jaw and the lower clamping jaw, and can also realize the locking and unlocking of the supporting platform 3 relative to the movable platform 2.

[0055] A plurality of locking members 44 may be provided on a support platform 3 , and a locking member 44 may be provided at each of the four corners of the square support platform 3 . The provision of a plurality of locking members 44 may improve the locking force between the support platform 3 and the movable platform 2 , and ensure the position accuracy of the support platform 3 .

[0056] In one embodiment, a chip sequencer is provided, the chip sequencer includes the chip motion platform in any of the above embodiments, and the chip sequencer also includes a liquid path system and an optical system. Of course, the chip sequencer also includes other components such as a controller.

[0057] The liquid path system is used to connect with the flow channel 51 of the chip 5 on the supporting platform 3. The liquid path system is also connected with a liquid reservoir or a liquid storage chamber. The liquid path system can inject samples or reagents in the liquid reservoir or the liquid storage chamber into the flow channel 51 of the chip 5. The liquid path system can also inject samples and reagents into the flow channel 51 of the chip 5 successively.

[0058] The optical system is arranged above the carrier platform 3 . The optical system has an imaging lens, which is arranged downward. The imaging lens is used to take pictures and images of the flow channel 51 of the chip 5 on the carrier platform 3 .

[0059] During the detection and photographing process, the chip motion platform can drive the carrier 3 to move along the first direction and the second direction to realize sequential photographing of multiple flow channels 51 of the chip 5. The chip motion platform has a rotation adjustment function, which can adjust the length direction of the flow channel 51 of the chip 5 to be parallel to the first direction, so that the imaging lens can accurately photograph the flow channel 51 in sequence along the first direction, ensuring the accuracy of imaging detection.

[0060] The above specific examples are used to illustrate the present invention, which are only used to help understand the present invention and are not intended to limit the present invention. For those skilled in the art of the present invention, some simple deductions, deformations or substitutions can be made based on the idea of ​​the present invention.

Claims

1. A chip sequencer, characterized in that: include: A chip motion platform, comprising a fixed platform, a mobile platform, a carrier platform, a mobile driving member and a rotation adjustment component, wherein the mobile platform is movable along a first direction and is arranged on the fixed platform, the carrier platform is arranged on the mobile platform, the carrier platform is used to fix a carrier chip, the mobile driving member is connected to the mobile platform, the mobile driving member is used to drive the mobile platform and the carrier platform to move along the first direction, the rotation adjustment component is connected to the carrier platform, and the rotation adjustment component is used to adjust the rotation angle of the carrier platform relative to the mobile platform; A fluid path system connected to the flow channel of the chip on the carrier and used to inject samples and / or reagents into the flow channel of the chip; as well as The optical system is arranged above the carrier platform and is used to take pictures and images of the flow channel of the chip on the carrier platform.

2. The chip sequencer according to claim 1, characterized in that: The rotation adjustment component is used to adjust the length direction of the flow channel of the chip on the carrier to rotate parallel to the first direction.

3. The chip sequencer according to claim 1, characterized in that: The rotation adjustment assembly includes an adjustment member, which can move along a second direction. The adjustment member is connected to the first side of the support platform. The second direction and the first direction are located in the same plane and are perpendicular to the first direction. The adjustment member moves along the second direction to drive the support platform to rotate.

4. The chip sequencer according to claim 3, characterized in that: The rotation adjustment assembly further includes an elastic member, the elastic member abuts against a second side surface of the support platform, the second side surface is a surface facing away from the first side surface, and the elastic member is used to eliminate a reverse clearance of the rotation of the support platform.

5. The chip sequencer according to claim 4, characterized in that: The adjusting member and the elastic member are arranged opposite to each other.

6. The chip sequencer according to claim 3, characterized in that: The rotation adjustment component also includes a mounting member, the mounting member is arranged on the moving platform, and the adjustment member is arranged on the mounting member.

7. The chip sequencer according to claim 2, characterized in that: The rotation adjustment assembly further includes a locking member, and the locking member is used to lock and fix the supporting platform to the fixing platform.

8. The chip sequencer according to claim 3, characterized in that: The supporting platform is rotatably connected to the moving platform via a rotating shaft, and the adjusting member is used to adjust the supporting platform to rotate around the rotating shaft.

9. The chip sequencer according to claim 4, characterized in that: The movable platform is provided with a first bearing platform and a second bearing platform, the first bearing platform and the second bearing platform are respectively provided with one adjusting member, and the first bearing platform and the second bearing platform correspond to the same elastic member.

10. The chip sequencer according to claim 9, characterized in that: The elastic member is squeezed between the first bearing platform and the second bearing platform, one end of the elastic member is connected to the first bearing platform, and the other end of the elastic member is connected to the second bearing platform.

11. A chip motion platform, characterized in that: include: Fixed table; A mobile platform, the mobile platform being movable along a first direction and arranged on the fixed platform; A carrier platform, which is disposed on the mobile platform and is used to fix the carrier chip; A mobile driving member, the mobile driving member is connected to the mobile platform and is used to drive the mobile platform and the supporting platform to move along the first direction; as well as A rotation adjustment component is connected to the carrier platform, and is used to adjust the carrier platform to rotate relative to the movable platform to adjust the length direction of the flow channel of the chip on the carrier platform to be parallel to the first direction.

12. The chip motion platform according to claim 11, characterized in that: The movable platform is provided with a first bearing platform and a second bearing platform, the rotation adjustment assembly includes an adjustment member and an elastic member, the first bearing platform and the second bearing platform are respectively provided with one adjustment member, and the first bearing platform and the second bearing platform correspond to the same elastic member.