Medical intermediate grinding machine
By designing a multi-stage crushing and screening pharmaceutical intermediate grinder, the problems of uneven crushing and screening in the prior art have been solved, and the consistency of particle size and grinding efficiency have been improved.
Patent Information
- Application Number
- CN202421595382.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-08
- Publication Date
- 2025-05-06
- Estimated Expiration
- 2034-07-08
AI Technical Summary
In the prior art, the pharmaceutical intermediates are crushed only once by a grinding rod, and the finished products after crushing are of different sizes, which cannot guarantee the appropriate size of the powder particles. For excessively large pharmaceutical intermediate particles, it is also time-consuming and labor-intensive.
A pharmaceutical intermediate grinder is designed, including a crushing box, grinding box, screening box and grinding assembly. The crushed medical intermediate is driven by a crushing motor and the crushed leaves. The rotating rod drives the grinding roller for further grinding, and the crushed pharmaceutical intermediate is screened through a screening plate and a filter.
Through multi-stage crushing and screening, the consistency of the particle size of pharmaceutical intermediates is ensured, the time and labor of screening are reduced, and the grinding efficiency is improved.
Smart Images

Figure CN222829751U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of pharmaceutical intermediate processing, in particular to a pharmaceutical intermediate grinding machine. Background Art
[0002] Pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. This kind of chemical product does not require a drug production license and can be produced in ordinary chemical plants. As long as it reaches a certain level, it can be used in drug synthesis. Many pharmaceutical intermediates need to be ground during synthesis.
[0003] The patent document with application number CN207769946U discloses a grinder for quickly grinding pharmaceutical intermediates, wherein a groove is arranged at the upper end of the side wall of the grinder, a grinding cover is arranged above the grinder, a connecting column is vertically connected to the bottom of the grinding cover, and the grinder and the grinding cover are connected by being inserted into the groove through the connecting column; a grinding rod passes through the grinding cover, and the grinding rod can move up and down and rotate along the grinding cover; a baffle is connected to the bottom of the grinding cover, and when the grinder and the grinding cover are connected, the baffle is in contact with and fits the inner wall of the grinder, the surface of the baffle away from the inner wall of the grinder is inclined, and the angle between the surface of the baffle away from the inner wall of the grinder and the surface close to the baffle is 15 degrees; a plurality of jet holes are arranged below the grinding cover, and a booster pump is arranged in the jet holes; a horizontal retractable baffle is arranged on the side wall of the grinder, one end of the baffle is fixed on the inner wall of the grinder, and the other end is inserted into the other side wall of the grinder by extension.
[0004] In the above-mentioned related technologies, the pharmaceutical intermediates are only crushed once by a grinding rod. The finished products after crushing are of different sizes, and the appropriate size of the powder particles cannot be guaranteed. For pharmaceutical intermediate particles that are too large, screening is required, which is time-consuming and labor-intensive. In response to the above problems, we have launched a pharmaceutical intermediate grinder. Utility Model Content
[0005] The utility model discloses a pharmaceutical intermediate grinder, which aims to solve the technical problems in the related art that the pharmaceutical intermediate is only crushed once by a grinding rod, the finished products after crushing are of different sizes, the appropriate size of the powder particles cannot be guaranteed, and the oversized pharmaceutical intermediate particles need to be screened, which is time-consuming and laborious.
[0006] In order to achieve the above purpose, the utility model adopts the following technical solutions:
[0007] A pharmaceutical intermediate grinding machine comprises a lower shell and a grinding assembly, wherein an upper shell is fixedly mounted on the top of the lower shell, a fixed bin is provided inside the upper shell, the lower shell is divided into two receiving bins by a partition, a crushing box, a grinding box and a screening box are fixedly mounted in sequence from top to bottom inside the fixed bin, a crushing bin is provided inside the crushing box, and a grinding bin is provided inside the grinding box;
[0008] The grinding assembly includes a rotating rod, which is rotatably connected to the inside of the crushing bin, a crushing blade is fixedly installed on the outside of the rotating rod and located inside the crushing bin, the bottom end of the rotating rod extends into the grinding bin and is fixedly installed with a grinding roller, a crushing motor is fixedly installed on the top of the upper shell, driving the top end of the rotating rod to extend into the inside of the upper shell and fixedly connected to the output end of the crushing motor, a feed pipe is fixedly installed through the top of the upper shell, and the bottom end of the feed pipe extends into the inside of the crushing bin.
[0009] By setting a crushing box, a grinding box, a screening box and a grinding component, the pharmaceutical intermediate is introduced into the crushing bin through a feed pipe, and through the grinding component, the crushing motor rotates to drive the rotating rod to rotate, and the pharmaceutical intermediate entering the crushing bin is further crushed by the crushing leaves. The crushing box and the grinding box are connected on one side through a No. 1 through slot, and the crushed pharmaceutical intermediate enters the grinding bin through the No. 1 through slot, and the grinding roller is driven by the rotating rod to further grind the pharmaceutical intermediate entering the grinding bin. The grinding box and the screening box are connected on one side through a No. 2 through slot, and the ground pharmaceutical intermediate enters the screening bin through the No. 2 through slot and is screened, which saves time and labor, and solves the technical problem in the related art that the pharmaceutical intermediate is crushed only once by a grinding rod, the finished product after crushing is of different sizes, the powder particle size cannot be guaranteed to be appropriate, and the overly large pharmaceutical intermediate particles need to be screened, which is time-consuming and labor-intensive.
[0010] In a preferred solution, a screening bin is provided inside the screening box, a screening plate is rotatably connected inside the screening bin via a rotating shaft, a discharge port is provided on one side of the screening box close to the two receiving bins, a filter is fixedly installed inside the discharge port close to the right receiving bin, a chassis is fixedly installed between the lower shell and the upper shell and close to the screening box, and a rotating motor is arranged inside the chassis for driving the rotating shaft to rotate.
[0011] Through the setting, the rotation of the shaft drives the screening plate to first bring the ground pharmaceutical intermediates to the discharge port on the right, and then filter them into the receiving bin on the right through the filter screen. The unfiltered large-particle pharmaceutical intermediates enter the receiving bin on the left through the discharge port on the left, which is beneficial to the screening of the ground pharmaceutical intermediates.
[0012] In a preferred embodiment, a cooling chamber No. 1 is provided on the inner wall of the crushing box, a water inlet pipe is fixedly installed through one side of the cooling chamber No. 1, a water outlet pipe is fixedly installed through the side of the cooling chamber No. 1 away from the water inlet pipe, and both the water inlet pipe No. 1 and the water outlet pipe No. 1 extend to the outside of the upper shell.
[0013] By setting up a No. 1 water inlet pipe and a No. 1 water outlet pipe to connect to the external circulating cold water tank through connecting pipes, it is beneficial to add cold water into the No. 1 cooling chamber through the No. 1 water inlet pipe, and then drain it through the No. 1 water outlet pipe, which is beneficial to cool down the heat generated by the rotation of the crushing blades during work.
[0014] In a preferred embodiment, a No. 2 cooling chamber is provided on the inner wall of the grinding box, a No. 2 water inlet pipe is fixedly installed through the side of the No. 2 cooling chamber close to the No. 1 water inlet pipe, and a No. 2 water outlet pipe is fixedly installed through the side of the No. 2 cooling chamber away from the No. 2 water inlet pipe, and both the No. 2 water inlet pipe and the No. 2 water outlet pipe extend to the outside of the upper shell.
[0015] By setting up a No. 2 water inlet pipe and a No. 2 water outlet pipe to connect to the external circulating cold water tank through connecting pipes, it is beneficial to add cold water into the No. 2 cooling chamber through the No. 2 water inlet pipe, and then drain it through the No. 2 water outlet pipe, which is beneficial to cool down the heat generated by the rotation of the grinding roller during operation.
[0016] In a preferred solution, the screening box is fixedly connected to the partition on one side close to the partition, a discharge pipe is symmetrically and fixedly installed at the bottom of the lower shell body and close to the two receiving bins, and a control panel is fixedly installed on the surface of the upper shell body.
[0017] The provision of a discharge pipe is conducive to the discharge of the pharmaceutical intermediates after screening in the two receiving bins, and the control panel is conducive to controlling the operation of the pulverizing motor and the rotating motor in the chassis.
[0018] In a preferred solution, the internal rotating shaft of the screening bin drives the screening plate to rotate clockwise, and the side of the screening plate close to the inner wall of the screening bin is rotatably connected to the screening bin.
[0019] The internal rotating shaft of the screening bin is arranged to drive the screening plate to rotate clockwise, which is beneficial to strengthen the screening of the ground pharmaceutical intermediates inside the screening bin and is more convenient to use.
[0020] The pharmaceutical intermediate grinding machine provided by the utility model has the following advantages:
[0021] First, by setting a crushing box, a grinding box, a screening box and a grinding component, the pharmaceutical intermediate is introduced into the crushing bin through a feed pipe, and through the grinding component, the crushing motor rotates to drive the rotating rod to rotate, and the pharmaceutical intermediate entering the crushing bin is further crushed by the crushing leaves, and the side where the crushing box and the grinding box are close to each other is connected through a No. 1 through slot, and the crushed pharmaceutical intermediate enters the grinding bin through the No. 1 through slot, and the grinding roller is driven by the rotating rod to further grind the pharmaceutical intermediate entering the grinding bin, and the side where the grinding box and the screening box are close to each other is connected through a No. 2 through slot, and the ground pharmaceutical intermediate enters the screening bin through the No. 2 through slot and is screened, which saves time and labor, and solves the technical problem in the related art that the pharmaceutical intermediate is only crushed once by a grinding rod, the finished product after crushing is of different sizes, the powder particle size cannot be guaranteed to be appropriate, and the overly large pharmaceutical intermediate particles need to be screened, which is time-consuming and labor-intensive. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 The utility model is a three-dimensional schematic diagram of a pharmaceutical intermediate grinding machine.
[0023] Figure 2 The utility model is a three-dimensional cross-sectional schematic diagram of a pharmaceutical intermediate grinding machine.
[0024] Figure 3 for Figure 2 Enlarged view of point A in the middle.
[0025] Figure 4 for Figure 2 Enlarged view of point B in the middle.
[0026] In the attached drawings: 1. lower shell; 11. partition; 12. material receiving bin; 13. material discharge pipe; 2. upper shell; 21. fixed bin; 22. material feed pipe; 3. crushing box; 31. crushing bin; 32. cooling chamber No. 1; 33. water inlet pipe No. 1; 34. water outlet pipe No. 1; 4. grinding box; 41. grinding bin; 42. cooling chamber No. 2; 43. water inlet pipe No. 2; 44. water outlet pipe No. 2; 5. screening box; 51. screening bin; 52. screening plate; 53. filter; 54. material discharge port; 55. chassis; 6. grinding assembly; 61. rotating rod; 62. crushing motor; 63. crushing blade; 64. grinding roller; 7. control panel. DETAILED DESCRIPTION
[0027] The technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. The components of the embodiments of the present application usually described and marked in the drawings here can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present application provided in the drawings is not intended to limit the scope of the application claimed for protection, but merely represents the selected embodiments of the present application. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without making creative work belong to the scope of protection of the present application.
[0028] The utility model discloses a pharmaceutical intermediate grinding machine which is mainly used for grinding pharmaceutical intermediates.
[0029] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4 A pharmaceutical intermediate grinding machine comprises: a lower shell 1 and a grinding assembly 6, an upper shell 2 is fixedly installed on the top of the lower shell 1, a fixed bin 21 is provided inside the upper shell 2, the lower shell 1 is divided into two receiving bins 12 by a partition 11, a crushing box 3, a grinding box 4 and a screening box 5 are fixedly installed in the fixed bin 21 from top to bottom, a crushing bin 31 is provided inside the crushing box 3, and a grinding bin 41 is provided inside the grinding box 4;
[0030] The grinding assembly 6 includes a rotating rod 61, which is rotatably connected to the inside of the crushing bin 31, and a crushing leaf 63 is fixedly installed on the outside of the rotating rod 61 and located inside the crushing bin 31. The bottom end of the rotating rod 61 extends to the inside of the grinding bin 41 and is fixedly installed with a grinding roller 64. A crushing motor 62 is fixedly installed on the top of the upper shell 2, driving the top end of the rotating rod 61 to extend to the inside of the upper shell 2 and be fixedly connected to the output end of the crushing motor 62. A feed pipe 22 is fixedly installed through the top of the upper shell 2, and the bottom end of the feed pipe 22 extends to the inside of the crushing bin 31.
[0031] Among them, a cooling chamber No. 1 32 is provided on the inner wall of the crushing box 3, a water inlet pipe 33 is fixedly installed on one side of the cooling chamber No. 1 32, and a water outlet pipe 34 is fixedly installed on the side of the cooling chamber No. 1 32 away from the water inlet pipe 33, and both the water inlet pipe 33 and the water outlet pipe 34 extend to the outside of the upper shell 2; by setting the water inlet pipe 33 and the water outlet pipe 34 to be connected to the external circulating cold water tank through the connecting pipe respectively, it is beneficial to add cold water into the cooling chamber No. 1 32 through the water inlet pipe 33, and then discharge it through the water outlet pipe 34, which is beneficial to cool down the heat generated by the rotation of the crushing leaves 63 during work.
[0032] Among them, a No. 2 cooling chamber 42 is opened on the inner wall of the grinding box 4, and a No. 2 water inlet pipe 43 is fixedly installed on the side of the No. 2 cooling chamber 42 close to the No. 1 water inlet pipe 33, and a No. 2 water outlet pipe 44 is fixedly installed on the side of the No. 2 cooling chamber 42 away from the No. 2 water inlet pipe 43, and the No. 2 water inlet pipe 43 and the No. 2 water outlet pipe 44 both extend to the outside of the upper shell 2; by arranging the No. 2 water inlet pipe 43 and the No. 2 water outlet pipe 44 to be connected to the external circulating cold water tank through connecting pipes, it is beneficial to add cold water into the No. 2 cooling chamber 42 through the No. 2 water inlet pipe 43, and then drain it out through the No. 2 water outlet pipe 44, which is beneficial to cool down the heat generated by the rotation of the grinding roller 64 during work.
[0033] Among them, the screening box 5 is fixedly connected to the partition 11 on one side close to the partition 11, a discharge pipe 13 is symmetrically and fixedly installed at the bottom of the lower shell 1 and close to the two receiving bins 12, and a control panel 7 is fixedly installed on the surface of the upper shell 2; the discharge pipe 13 is arranged to facilitate the export of the pharmaceutical intermediates after screening inside the two receiving bins 12, and the control panel 7 is conducive to controlling the operation of the crushing motor 62 and the rotating motor inside the chassis 55.
[0034] In this embodiment, by setting a crushing box 3, a grinding box 4, a screening box 5 and a grinding assembly 6, the pharmaceutical intermediate is introduced into the crushing bin 31 through the feed pipe 22, and through the grinding assembly 6, the crushing motor 62 rotates to drive the rotating rod 61 to rotate, and the pharmaceutical intermediate entering the crushing bin 31 is further crushed by the crushing leaves 63. The crushing box 3 and the grinding box 4 are connected on one side by the No. 1 through groove, and the crushed pharmaceutical intermediate enters the grinding bin 41 through the No. 1 through groove, and the grinding roller 64 is driven by the rotating rod 61 to rotate to further grind the pharmaceutical intermediate entering the grinding bin 41. The grinding box 4 and the screening box 5 are connected on one side by the No. 2 through groove, and the ground pharmaceutical intermediate enters the screening bin 51 through the No. 2 through groove and is screened, which saves time and effort, and solves the technical problem that in the related art, the pharmaceutical intermediate is crushed only once by the grinding rod, the finished product after crushing is of different sizes, and the powder particle size cannot be guaranteed to be appropriate. For the pharmaceutical intermediate particles that are too large, screening is required, which is time-consuming and labor-intensive.
[0035] In the above technical solution, considering the problem of screening the ground pharmaceutical intermediates, in order to solve such problems, the specific operations are as follows:
[0036] Reference Figure 2 and Figure 4In a preferred embodiment, a screening bin 51 is provided inside the screening box 5, a screening plate 52 is rotatably connected to the screening bin 51 through a rotating shaft, a discharge port 54 is provided on one side of the screening box 5 close to the two receiving bins 12, a filter screen 53 is fixedly installed inside the discharge port 54 close to the right receiving bin 12, a chassis 55 is fixedly installed between the lower shell 1 and the upper shell 2 and close to the screening box 5, and a rotating motor is provided inside the chassis 55 for driving the rotating shaft to rotate;
[0037] Among them, the internal rotating shaft of the screening bin 51 drives the screening plate 52 to rotate clockwise, and the side of the screening plate 52 close to the inner wall of the screening bin 51 is connected to the screening bin 51 in a rotational manner; by setting the internal rotating shaft of the screening bin 51 to drive the screening plate 52 to rotate clockwise, it is beneficial to strengthen the screening of the ground pharmaceutical intermediates inside the screening bin 51, and it is more convenient to use.
[0038] In this embodiment, the rotating shaft drives the screening plate 52 to first bring the ground pharmaceutical intermediate to the discharge port 54 on the right, and then filters it through the filter screen 53 and enters the receiving bin 12 on the right. The unfiltered large-particle pharmaceutical intermediate enters the receiving bin 12 on the left through the discharge port 54 on the left, which is beneficial to the screening of the ground pharmaceutical intermediate.
[0039] Working principle: When in use, by setting the crushing box 3, the grinding box 4, the screening box 5 and the grinding assembly 6, the pharmaceutical intermediate is introduced into the crushing bin 31 through the feed pipe 22, and through the grinding assembly 6, the crushing motor 62 rotates to drive the rotating rod 61 to rotate, and the pharmaceutical intermediate entering the crushing bin 31 is further crushed by the crushing leaves 63, and the side where the crushing box 3 and the grinding box 4 are close to each other is connected through the No. 1 through groove, and the crushed pharmaceutical intermediate enters the grinding bin 41 through the No. 1 through groove, and the grinding roller 64 is driven by the rotating rod 61 to rotate to further grind the pharmaceutical intermediate entering the grinding bin 41, and the side where the grinding box 4 and the screening box 5 are close to each other is connected through the No. 2 through groove, and the ground pharmaceutical intermediate enters the screening bin 51 through the No. 2 through groove and is screened, which saves time and effort, and solves the technical problem that in the related art, the pharmaceutical intermediate is only crushed once by the grinding rod, the finished product after crushing is of different sizes, and the powder particle size cannot be guaranteed to be appropriate. For the pharmaceutical intermediate particles that are too large, screening is required, which is time-consuming and labor-intensive.
[0040] The above are only preferred specific implementations of the utility model, but the protection scope of the utility model is not limited to them. The replacement can be a replacement of part of the structure, device, method step, or a complete technical solution. Equivalent replacement or change based on the technical solution of the utility model and its utility model concept should be included in the protection scope of the utility model.
Claims
1. A pharmaceutical intermediate grinding machine, comprising a lower housing (1) and a grinding assembly (6), characterized in that: An upper shell (2) is fixedly mounted on the top of the lower shell (1); a fixed bin (21) is provided inside the upper shell (2); the interior of the lower shell (1) is divided into two material receiving bins (12) by a partition (11); a crushing box (3), a grinding box (4) and a screening box (5) are fixedly mounted in order from top to bottom inside the fixed bin (21); a crushing bin (31) is provided inside the crushing box (3); and a grinding bin (41) is provided inside the grinding box (4); The grinding assembly (6) comprises a rotating rod (61), the inside of the crushing bin (31) is rotatably connected with the rotating rod (61), a crushing blade (63) is fixedly installed on the outside of the rotating rod (61) and located inside the crushing bin (31), the bottom end of the rotating rod (61) extends into the inside of the grinding bin (41) and is fixedly installed with a grinding roller (64), a crushing motor (62) is fixedly installed on the top of the upper shell (2), driving the top end of the rotating rod (61) to extend into the inside of the upper shell (2) and be fixedly connected to the output end of the crushing motor (62), and a feed pipe (22) is fixedly installed through the top of the upper shell (2), and the bottom end of the feed pipe (22) extends into the inside of the crushing bin (31).
2. A pharmaceutical intermediate grinding machine according to claim 1, characterized in that: The screening box (5) is provided with a screening bin (51) inside, and a screening plate (52) is rotatably connected to the screening bin (51) via a rotating shaft. The screening box (5) is provided with a discharge port (54) on one side close to the two receiving bins (12), and a filter screen (53) is fixedly installed inside the discharge port (54) close to the right receiving bin (12). A machine box (55) is fixedly installed between the lower shell (1) and the upper shell (2) and close to the screening box (5), and a rotating motor is arranged inside the machine box (55) for driving the rotating shaft to rotate.
3. A pharmaceutical intermediate grinding machine according to claim 1, characterized in that: The inner wall of the crushing box (3) is provided with a first cooling chamber (32), a first water inlet pipe (33) is fixedly installed through one side of the first cooling chamber (32), and a first water outlet pipe (34) is fixedly installed through the side of the first cooling chamber (32) away from the first water inlet pipe (33), and both the first water inlet pipe (33) and the first water outlet pipe (34) extend to the outside of the upper shell (2).
4. A pharmaceutical intermediate grinding machine according to claim 3, characterized in that: The inner wall of the grinding box (4) is provided with a second cooling chamber (42); a second water inlet pipe (43) is fixedly installed through a side of the second cooling chamber (42) close to the first water inlet pipe (33); a second water outlet pipe (44) is fixedly installed through a side of the second cooling chamber (42) away from the second water inlet pipe (43); and both the second water inlet pipe (43) and the second water outlet pipe (44) extend to the outside of the upper shell (2).
5. A pharmaceutical intermediate grinding machine according to claim 1, characterized in that: The screening box (5) is fixedly connected to the partition (11) on one side thereof close to the partition (11); a discharge pipe (13) is symmetrically and fixedly installed through the bottom of the lower shell (1) and close to the two receiving bins (12); and a control panel (7) is fixedly installed on the surface of the upper shell (2).
6. A pharmaceutical intermediate grinding machine according to claim 2, characterized in that: The internal rotating shaft of the screening bin (51) drives the screening plate (52) to rotate clockwise, and the side of the screening plate (52) close to the inner wall of the screening bin (51) is connected to the screening bin (51) in abutting rotation.
Citation Information
Patent Citations
Grind intermediate's grinding machine fast
CN207769946U