Efficient temperature control enzymolysis reaction device for preparing chitosan oligosaccharide

Abstract

The utility model belongs to the field of chitosan oligosaccharide preparation, and particularly relates to an efficient temperature control enzymolysis reaction device for chitosan oligosaccharide preparation, which comprises a base, a containing groove is arranged at the top of the base, mounting frames are fixedly mounted on the left side of the top of the base and are positioned on the front side and the rear side of the containing groove, a reaction vessel is rotatably connected between the mounting frames, and the reaction vessel is provided with a temperature control device. A heating device is arranged at the bottom of the reaction vessel, the top of the reaction vessel is communicated with a discharge port, a sealing cover is arranged at the top of the discharge port, and fixing clamps are clamped on the two sides of the sealing cover and the discharge port; according to the reaction vessel, raw materials in the reaction vessel are heated through the arrangement of the electric heating rod, the reaction vessel is electrically controlled and can be rapidly heated, and meanwhile, the heating temperature of the electric heating rod can be controlled by controlling current, so that the temperature requirement of raw material reaction is met; a temperature sensor is arranged for performing auxiliary monitoring on the temperature in the reaction vessel, so that the reaction of the raw materials is facilitated.

Description

Technical Field

[0001] The utility model relates to the field of chitosan oligosaccharide preparation, in particular to a high-efficiency temperature-controlled enzymatic hydrolysis reaction device for chitosan oligosaccharide preparation. Background Art

[0002] Chitosan oligosaccharide, also known as chitosan oligosaccharide and low-molecular-weight chitosan, is an oligosaccharide product with a degree of polymerization between 2 and 20 obtained by degrading chitosan through a special bio-enzyme technology (there are also reports of using chemical degradation and microwave degradation technology). The molecular weight is ≤3200Da. It is a low molecular weight product with good water solubility, great functional effects and high biological activity. It has many unique functions that chitosan does not have, such as higher solubility, complete solubility in water, and easy absorption and utilization by organisms. Its function is 14 times that of chitosan.

[0003] Chitosan oligosaccharides are produced by an acid-base method or an enzymatic method. When produced by the enzymatic method, an enzymatic reaction device is required. The prior art discloses a high-efficiency temperature-controlled enzymatic reaction device for preparing chitosan oligosaccharides (authorization announcement number CN217809475U). This patented technology can achieve two fast and slow heating modes by setting two steam pipes. The setting of the stirring unit and the lifting unit makes the material temperature rise more uniform. A plurality of temperature sensors are set to more accurately monitor the temperature of different areas in the kettle.

[0004] Although this solution can achieve temperature control and stirring of the reactants in actual use, it is heated by steam in actual use, which requires external steam equipment to increase costs. At the same time, heating by steam causes the temperature to rise slowly and the temperature is inconvenient to control, which cannot meet the needs of use. Therefore, those skilled in the art provide a high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides to solve the problems raised in the above background technology. Utility Model Content

[0005] In order to make up for the shortcomings of the prior art, heating by steam in actual use requires external steam equipment to increase costs. At the same time, heating by steam leads to a slow temperature speed and inconvenient temperature control. The utility model proposes a high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides.

[0006] The utility model solves the technical problem by adopting the following technical solution: a high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharide, comprising a base, a holding tank is arranged on the top of the base, mounting frames are fixedly installed on the left side of the top of the base and located on the front and rear sides of the holding tank, a reaction dish is rotatably connected between the mounting frames, a heating device is arranged on the bottom of the reaction dish, a discharge port is communicated with the top of the reaction dish, a sealing cover is arranged on the top of the discharge port, and fixing clips are clamped on both sides of the sealing cover and the discharge port;

[0007] The heating device includes a semi-annular mounting plate, which is arranged at the bottom of the reaction vessel, and evenly distributed electric heating rods are fixedly installed on the inner side of the semi-annular mounting plate, and the electric heating rods penetrate into the interior of the reaction vessel. A temperature sensor is inserted into the top of the sealing cover, and the bottom of the temperature sensor penetrates the sealing cover and extends to the inside of the discharge port.

[0008] Preferably, a motor is fixedly mounted on the front side of the mounting frame at the front side of the top of the base, and the output end of the motor passes through the mounting frame and is fixedly connected to the front side of the reaction vessel.

[0009] Preferably, a pressure relief valve is interspersed inside the sealing cover, and the bottom of the pressure relief valve passes through the sealing cover and extends to the bottom of the sealing cover.

[0010] Preferably, a receiving cavity is provided at the top of the discharge port, a sealing ring is provided inside the receiving cavity, and the top of the sealing ring contacts the bottom of the sealing cover.

[0011] Preferably, a controller is fixedly mounted on the front side of the mounting frame on the front side of the top of the base, and a discharge port is embedded in the bottom of the controller.

[0012] Preferably, two guide grooves are provided on the top of the base, and guide wheels are fixedly mounted on both sides of the bottom of the containing groove, and the guide wheels are slidably connected to the inside of the guide grooves.

[0013] Preferably, a discharge pipe is connected to the right side of the containing tank, and a valve is fixedly installed inside the discharge pipe.

[0014] The utility model is beneficial in that:

[0015] The utility model heats the raw materials inside the reaction vessel by setting an electric heating rod, and the reaction vessel is electrically controlled and can be heated quickly, and the current can be controlled to control the heating temperature of the electric heating rod, thereby meeting the temperature requirements of the raw material reaction, and the temperature sensor is set to assist in monitoring the temperature inside the reaction vessel to facilitate the reaction of the raw materials. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 It is a schematic diagram of the structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the reaction vessel structure of the utility model;

[0019] Figure 3 This is a schematic diagram of the structure of the holding tank of the utility model;

[0020] Figure 4 This is a schematic diagram of the heating device structure of the utility model;

[0021] Figure 5 It is a schematic diagram of the sealing cover structure of the utility model.

[0022] In the figure: 1. base; 2. holding tank; 3. valve; 4. discharge pipe; 5. guide groove; 6. heating device; 601. semi-circular mounting plate; 602. electric heating rod; 603. temperature sensor; 7. mounting frame; 8. sealing cover; 9. reaction vessel; 10. motor; 11. controller; 12. discharge port; 13. sealing ring; 14. accommodating chamber; 15. fixing clamp; 16. guide wheel; 17. pressure relief valve; 18. power interface. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] The following is combined with Figure 1-5 To further explain this application in detail,

[0025] The present application discloses a highly efficient temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides. Figure 1 , Figure 4 and Figure 5 A high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides, comprising a base 1, a holding tank 2 is arranged on the top of the base 1, mounting frames 7 are fixedly installed on the left side of the top of the base 1 and located on the front and rear sides of the holding tank 2, a reaction vessel 9 is rotatably connected between the mounting frames 7, a heating device 6 is arranged at the bottom of the reaction vessel 9, a discharge port 12 is connected to the top of the reaction vessel 9, a sealing cover 8 is arranged on the top of the discharge port 12, and fixing clips 15 are clamped on both sides of the sealing cover 8 and the discharge port 12;

[0026] The heating device 6 includes a semi-annular mounting plate 601, which is arranged at the bottom of the reaction vessel 9. Evenly distributed electric heating rods 602 are fixedly installed on the inner side of the semi-annular mounting plate 601. The electric heating rods 602 penetrate into the interior of the reaction vessel 9. A temperature sensor 603 is inserted into the top of the sealing cover 8. The bottom of the temperature sensor 603 penetrates the sealing cover 8 and extends to the inside of the discharge port 12.

[0027] Reference Figure 1 A motor 10 is fixedly installed on the front side of the mounting frame 7 on the front side of the top of the base 1. The output end of the motor 10 passes through the mounting frame 7 and is fixedly connected to the front side of the reaction dish 9. The motor 10 is used to drive the reaction dish 9 to rotate, thereby realizing the rotation of the internal raw materials and enzymes so that the raw materials and enzymes are evenly mixed to accelerate the reaction. At the same time, the raw materials and enzymes are dispersed by the setting of the electric heating rod 602 so that the two are evenly mixed.

[0028] Reference Figure 1 and Figure 5 A pressure relief valve 17 is interspersed inside the sealing cover 8. The bottom of the pressure relief valve 17 penetrates the sealing cover 8 and extends to the bottom of the sealing cover 8. The pressure relief valve 17 is used to relieve the pressure inside the reaction vessel 9 when the air pressure inside the reaction vessel 9 is too high during the reaction, thereby ensuring the overall reaction stability.

[0029] Reference Figure 1 A accommodating chamber 14 is provided at the top of the discharge port 12, and a sealing ring 13 is provided inside the accommodating chamber 14. The top of the sealing ring 13 contacts the bottom of the sealing cover 8. The sealing ring 13 is accommodated by the setting of the accommodating chamber 14. The sealing ring 13 is increased by the setting of the sealing ring 13 to increase the seal between the discharge port 12 and the sealing cover 8. At the same time, the setting of the discharge port 12 facilitates the addition of raw materials and enzymes into the reaction vessel 9 and then discharges the chitosan oligosaccharide after the reaction in the reaction vessel 9.

[0030] Reference Figure 1 A controller 11 is fixedly installed on the front side of the mounting frame 7 on the top front side of the base 1, and a power interface 18 is embedded at the bottom of the controller 11. The motor 10, the electric heating rod 602 and the temperature sensor 603 are controlled by the setting of the controller 11, so that the electric heating rod 602 can be controlled to heat the inside of the reaction dish 9.

[0031] Reference Figure 1 and Figure 3 Two guide grooves 5 are provided on the top of the base 1, and guide wheels 16 are fixedly installed on both sides of the bottom of the containing groove 2. The guide wheels 16 are slidably connected to the inside of the guide groove 5. The reacted chitosan oligosaccharide is accommodated by the setting of the containing groove 2, and the containing groove 2 is moved by the cooperation between the guide groove 5 and the guide wheel 16 to facilitate the discharge of chitosan oligosaccharide.

[0032] Reference Figure 1 and Figure 3 The right side of the holding tank 2 is connected with a discharge pipe 4, and a valve 3 is fixedly installed inside the discharge pipe 4. The discharge pipe 4 is opened and closed by setting the valve 3, and the chitosan oligosaccharide discharged from the reaction vessel 9 inside the holding tank 2 is discharged through the setting of the discharge pipe 4.

[0033] Working principle: remove the fixing clamp 15 and the sealing cover 8 from the top of the discharge port 12, inject the raw materials and enzymes required for the production of chitosan oligosaccharides into the interior of the reaction vessel 9, place the sealing cover 8 on the top of the discharge port 12 and connect it with the sealing cover 8 and the discharge port 12 through the fixing clamp 15. After the connection is completed, according to the temperature required for the reaction, the controller 11 controls the electric heating rod 602 to turn on, the raw materials and enzymes in the reaction vessel 9 are heated by the electric heating rod 602, and the temperature in the reaction vessel 9 is monitored by the temperature sensor 603. At the same time, the controller 11 controls the motor 10 to turn on, and the temperature sensor 603 controls the motor 10 to turn on the motor 10. The motor 10 drives the reaction vessel 9 to rotate. While the reaction vessel 9 rotates, the raw materials and enzymes inside the reaction vessel 9 are mixed and reacted under the obstruction and dispersion of the electric heating rod 602. After the reaction is completed, the containing tank 2 moves to the bottom of the reaction vessel 9 under the action of the guide groove 5 and the guide wheel 16, the fixing clamp 15 is removed, the sealing cover 8 is removed, and the reaction vessel 9 is driven by the motor 10 to rotate so that the discharge port 12 moves to the bottom and the chitosan oligosaccharides generated by the internal reaction are discharged into the inside of the containing tank 2. After the discharge is completed, the containing tank 2 is moved to the right, the valve 3 is opened, and the chitosan oligosaccharides inside the containing tank 2 are discharged through the discharge pipe 4.

[0034] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments, and the above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, and these changes and improvements fall within the scope of the utility model to be protected.

Claims

1. A high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides, characterized in that: The invention comprises a base (1), a containing groove (2) is arranged on the top of the base (1), mounting frames (7) are fixedly installed on the left side of the top of the base (1) and located on the front and rear sides of the containing groove (2), a reaction vessel (9) is rotatably connected between the mounting frames (7), a heating device (6) is arranged at the bottom of the reaction vessel (9), the top of the reaction vessel (9) is connected to a discharge port (12), a sealing cover (8) is arranged on the top of the discharge port (12), and fixing clips (15) are clamped on both sides of the sealing cover (8) and the discharge port (12); The heating device (6) comprises a semi-annular mounting plate (601), wherein the semi-annular mounting plate (601) is arranged at the bottom of the reaction vessel (9), and evenly distributed electric heating rods (602) are fixedly installed on the inner side of the semi-annular mounting plate (601), wherein the electric heating rods (602) penetrate into the interior of the reaction vessel (9), and a temperature sensor (603) is inserted into the top of the sealing cover (8), and the bottom of the temperature sensor (603) penetrates the sealing cover (8) and extends to the interior of the discharge port (12).

2. The high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides according to claim 1, characterized in that: A motor (10) is fixedly mounted on the front side of the mounting frame (7) at the top front side of the base (1), and an output end of the motor (10) passes through the mounting frame (7) and is fixedly connected to the front side of the reaction vessel (9).

3. The high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides according to claim 1, characterized in that: A pressure relief valve (17) is inserted into the interior of the sealing cover (8), and the bottom of the pressure relief valve (17) passes through the sealing cover (8) and extends to the bottom of the sealing cover (8).

4. The high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides according to claim 1, characterized in that: The top of the discharge port (12) is provided with a receiving cavity (14), the interior of the receiving cavity (14) is provided with a sealing ring (13), and the top of the sealing ring (13) is in contact with the bottom of the sealing cover (8).

5. The high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides according to claim 1, characterized in that: A controller (11) is fixedly mounted on the front side of the mounting frame (7) at the top front side of the base (1), and a power supply interface (18) is embedded at the bottom of the controller (11).

6. The high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides according to claim 1, characterized in that: Two guide grooves (5) are provided on the top of the base (1), and guide wheels (16) are fixedly installed on both sides of the bottom of the containing groove (2), and the guide wheels (16) are slidably connected to the inside of the guide grooves (5).

7. The high-efficiency temperature-controlled enzymatic hydrolysis reaction device for preparing chitosan oligosaccharides according to claim 1, characterized in that: The right side of the containing tank (2) is connected to a discharge pipe (4), and a valve (3) is fixedly installed inside the discharge pipe (4).

Images