Chemiluminescence immunoassay analyzer

By designing a mixing mechanism and a cushioning mechanism in a chemiluminescence immunoassay, the problems of sample and reagent mixing and feed control in the prior art are solved, and automated feed control and instrument stability protection are achieved, and analysis efficiency and data accuracy are improved.

CN222838069UActive Publication Date: 2025-05-06SHENZHEN ZHOUHONG MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202421063779.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-16
Publication Date
2025-05-06
Estimated Expiration
2034-05-16

AI Technical Summary

Technical Problem

The existing chemiluminescence immunoassay instruments do not have the function of mixing samples with reagents, and it is not convenient to control the feed of samples and reagents separately, resulting in poor proportioning effect and affecting the analysis data.

Method used

A chemiluminescent immunoassay device is designed, including a mixing mechanism and a cushioning mechanism. The mixing mechanism realizes automatic feed control of reagents or samples through the design of gear transmission and partition plates. The cushioning mechanism reduces vibration generated by the servo motor through the combination of cushioning plate, slider, slider and buffer spring, and protects the stability and accuracy of the instrument.

Benefits of technology

It realizes automatic feed control of reagents or samples, reduces manual operations, improves work efficiency, and ensures consistency and accuracy of operations. Through the design of the cushioning mechanism, the stability and accuracy of the instrument are protected and the service life is extended.

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Abstract

The utility model discloses a chemiluminescence immunoassay analyzer, which relates to the technical field of chemiluminescence immunoassay analyzer equipment and comprises a base, a servo motor, a transmission rod, an incomplete gear, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears, driven gears and driven gears. By means of the characteristics of the incomplete gear, when the driven gear on one side rotates, the driven gear at the other end is in a static state, the driven gear at one end can rotate to drive the partition plate in the conveying groove at the upper end of the reagent feeding port to rotate through the fixing piece, and when the partition plate is separated from the reagent feeding port, the reagent is discharged; similarly, after the partition plate in the conveying groove at the upper end of the reagent feeding port is reset, the driven gear on one side of the reagent feeding port is in a static state, and the partition plate in the conveying groove at the upper end of the sample feeding port at the other end is matched with the fixing piece through rotation of the driven gear on the same side to drive the fixing piece to rotate, so that the samples are discharged.
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Description

Technical Field

[0001] The utility model relates to the technical field of chemiluminescent immunoassay analyzer equipment, in particular to a chemiluminescent immunoassay analyzer. Background Art

[0002] Chemiluminescent labeling immunoassay, also known as chemiluminescent immunoassay (CLIA), is an immunoassay method that directly labels antigens or antibodies with chemiluminescent agents. The chemiluminescent immunoassay instrument consists of two parts, namely the immunoreaction system and the chemiluminescent analysis system. The chemiluminescent analysis system uses the catalysis of the chemiluminescent substance and the oxidation of the oxidant to form an excited intermediate. When this excited intermediate returns to a stable ground state, it simultaneously emits a photon (hM), and the light quantum yield is measured using a luminescent signal measuring instrument. The immunoreaction system is to directly label the luminescent substance (generating an excited intermediate under the excitation of the reactant) on the antigen (chemiluminescent immunoassay) or antibody (immunochemiluminescent assay), or the enzyme acts on the luminescent substrate.

[0003] The chemiluminescent immunoassay analyzer needs to fully mix the sample and the reagent before analysis, and can only analyze and test them after mixing. However, the existing chemiluminescent immunoassay analyzer does not have the function of mixing the sample and the reagent, and it is not convenient to control the feeding of the sample and the reagent separately, resulting in poor ratio effect, affecting the subsequent analysis data. Therefore, those skilled in the art provide a chemiluminescent immunoassay analyzer to solve the problems raised in the above background technology. Utility Model Content

[0004] The purpose of the utility model is to provide a chemiluminescent immunoassay analyzer to solve the problems raised in the above background technology.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A chemiluminescence immunoassay analyzer comprises a base, a mixing mechanism and a shock absorbing mechanism. The upper end of the base is provided with a chemiluminescence immunoassay analyzer body, a mixing box is provided inside the chemiluminescence immunoassay analyzer body, a cover plate is movably connected to the upper end of the mixing box, a reagent feed port is provided at one end of the upper end surface of the cover plate, a sample feed port is provided at the other end of the upper end surface of the cover plate, a servo motor is provided at the center of the cover plate, a mixing mechanism is provided at the bottom end of the servo motor, and shock absorbing mechanisms are provided at both left and right ends of the mixing box.

[0007] As a further solution of the utility model: a transmission rod is fixedly connected to the bottom end of the servo motor, an incomplete gear is fixedly connected to the upper end of the transmission rod, driven gears are provided at both left and right ends of the incomplete gear, connecting rods are provided at the bottom ends of the driven gears, the connecting rods are movably connected to the mixing box, transmission grooves are provided on the outer walls of the reagent feed port and the sample feed port, partition plates are movably connected in the transmission grooves, fixing parts are fixedly connected to the upper end faces of the driven gears, and the fixing parts are fixedly connected to the partition plates on the same side.

[0008] As a further solution of the utility model: the transmission rod is connected to the mixing box sleeve, the bottom end of the transmission rod is fixedly connected to a rotating rod, the outer side wall of the rotating rod is provided with multiple linkage sleeves, the outer side walls of the linkage sleeves are fixedly connected to multiple mixing blades, and the other ends of the mixing blades are fixedly connected to a mixing cover.

[0009] As a further solution of the utility model: shock-absorbing plates are provided on the side walls at both ends of the mixing box, and slide grooves are provided at the other ends of the shock-absorbing plates. A pair of sliders are slidably connected in the slide grooves, and the other ends of the sliders are fixedly connected to hinged rods, and the other ends of the hinged rods are hinged to hinged seats, and the hinged seats are fixedly connected to the inner side walls of the chemiluminescence immunoassay analyzer body, and buffer springs are fixedly connected between the hinged rods on the same side.

[0010] As a further solution of the utility model: the incomplete gear is meshed with the driven gear.

[0011] Compared with the prior art, the utility model has the following beneficial effects: the utility model is provided with a mixing mechanism, and through the transmission cooperation between gears and the design of the partition plate, the automatic feeding control of reagents or samples can be realized, which can reduce manual operation and improve work efficiency. In some occasions where repetitive operations are required, the consistency and accuracy of the operation can be guaranteed, and the feeding amount and speed of the reagents or samples can be accurately controlled by controlling the forward and reverse rotation of the servo motor. When the transmission rod rotates, the rotating rod is driven to perform a circular motion, so that the mixing blades, the mixing cover and other components are mixed synchronously, and the samples and reagents can be fully mixed, thereby improving the mixing effect and product quality;

[0012] Because the shock absorbing mechanism is provided, the setting of the shock absorbing plate, the slide groove and the slider can effectively reduce the vibration generated by the servo motor from being transmitted to other functional components of the chemiluminescence immunoassay analyzer body, thereby protecting the stability and accuracy of the instrument. Through the design of the hinged rod and the buffer spring, part of the vibration force can be transferred to the shock absorbing plate, and through the buffering effect of the spring, the influence of the vibration on the instrument body can be further reduced, the service life of the instrument can be extended, the influence of the vibration on the instrument can be reduced, the stability and accuracy of the instrument can be maintained, and the test results of the chemiluminescence immunoassay can be ensured to be accurate and reliable. The utility model relates to a chemiluminescence immunoassay analyzer, which is simple and reasonable in structure design and convenient and quick to operate. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 The figure is a schematic diagram of the structure of a chemiluminescent immunoassay analyzer.

[0014] Figure 2 A schematic diagram of the exploded structure of a mixing box in a chemiluminescent immunoassay analyzer.

[0015] Figure 3 This is a schematic diagram of the enlarged structure at A in a chemiluminescent immunoassay analyzer.

[0016] Figure 4 The figure is a schematic diagram of the structure of a mixing blade in a chemiluminescent immunoassay analyzer.

[0017] Figure 5 It is a schematic diagram of the front cross-sectional structure of a chemiluminescent immunoassay analyzer.

[0018] In the figure: 1-base, 2-chemiluminescent immunoassay analyzer body, 3-mixing box, 4-cover, 5-reagent feed port, 6-sample feed port, 7-servo motor, 8-transmission rod, 9-incomplete gear, 10-driven gear, 11-transmission trough, 12-partition plate, 13-fixing part, 14-connecting rod, 15-discharge port, 16-rotating rod, 17-linkage sleeve, 18-mixing blade, 19-mixing cover, 20-hinged seat, 21-hinged rod, 22-buffer spring, 23-slider, 24-slide, 25-shock-absorbing plate. DETAILED DESCRIPTION

[0019] See also Figures 1 to 5In the embodiment of the utility model, a chemiluminescent immunoassay analyzer includes a base 1, a chemiluminescent immunoassay analyzer body 2, a mixing box 3, a cover plate 4, a reagent feed port 5, a sample feed port 6, a servo motor 7, a transmission rod 8, an incomplete gear 9, a driven gear 10, a transmission slot 11, a partition plate 12, a fixing member 13, a connecting rod 14, a discharge port 15, a rotating rod 16, a linkage sleeve 17, a mixing blade 18, a mixing cover 19, an articulated seat 20, an articulated rod 21, a buffer spring 22, a slider 23, a slide 24, and a shock absorbing plate 25; the upper end of the base 1 is provided with a chemiluminescent immunoassay analyzer body 2, a mixing box 3, a cover plate 4, a reagent feed port 5, a sample feed port 6, a servo motor 7, a transmission rod 8, an incomplete gear 9, a driven gear 10, a transmission slot 11, a partition plate 12, a fixing member 13, a connecting rod 14, a discharge port 15, a rotating rod 16, a linkage sleeve 17, a mixing blade 18, a mixing cover 19, a hinge seat 20, a hinge rod 21, a buffer spring 22, a slider 23, a slide 24, and a shock absorbing plate 25; a chemiluminescent immunoassay analyzer body 2 The luminescent immunoassay analyzer body 2 is provided with a mixing box 3 inside the chemiluminescent immunoassay analyzer body 2, the upper end of the mixing box 3 is movably connected with a cover plate 4, one end of the upper end surface of the cover plate 4 is provided with a reagent feed port 5, and the other end of the upper end surface of the cover plate 4 is provided with a sample feed port 6. A servo motor 7 is provided at the center of the cover plate 4, and a mixing mechanism is provided at the bottom of the servo motor 7. Shock-absorbing mechanisms are provided at both ends of the mixing box 3. A transmission rod 8 is fixedly connected to the bottom end of the servo motor 7, and an incomplete gear 9 is fixedly connected to the upper end of the transmission rod 8. A driven gear is provided at both ends of the incomplete gear 9. 10, the bottom end of the driven gear 10 is provided with a connecting rod 14, and the connecting rod 14 is movably connected to the mixing box 3, the outer walls of the reagent feed port 5 and the sample feed port 6 are provided with a transmission groove 11, and the transmission groove 11 is movably connected with a partition plate 12, and the upper end surface of the driven gear 10 is fixedly connected with a fixing member 13, and the fixing member 13 is fixedly connected to the partition plate 12 on the same side, and the transmission rod 8 is sleeve-connected with the mixing box 3, and the bottom end of the transmission rod 8 is fixedly connected with a rotating rod 16, and the outer wall of the rotating rod 16 is provided with a plurality of linkage sleeves 17, and the outer wall of the linkage sleeve 17 is fixedly connected with a plurality of mixing blades The mixing blades 18 are fixedly connected to the mixing cover 19 at the other ends. The side walls at both ends of the mixing box 3 are provided with damping plates 25. The other ends of the damping plates 25 are provided with slide grooves 24. A pair of sliders 23 are slidably connected in the slide grooves 24. The other ends of the sliders 23 are fixedly connected to hinged rods 21. The other ends of the hinged rods 21 are hinged to hinge seats 20. The hinge seats 20 are fixedly connected to the inner side walls of the chemiluminescence immunoassay analyzer body 2. Buffer springs 22 are fixedly connected between the hinged rods 21 on the same side. The incomplete gear 9 is meshed with the driven gear 10.

[0020] The working principle of the utility model is: start the servo motor 7, the servo motor 7 drives the transmission rod 8 to rotate, the transmission rod 8 can drive the incomplete gear 9 to rotate, and the incomplete gear 9 is meshed with the driven gears 10 at both ends. Through the characteristics of the incomplete gear 9, when the driven gear 10 on one side rotates, the driven gear 10 on the other end is in a stationary state, so that the driven gear 10 at one end can be rotated through the fixing member 13 to drive the partition plate 12 inside the transmission groove 11 at the upper end of the reagent feed port 5 to rotate. When the partition plate 12 is separated from the reagent feed port 5, the reagent is discharged. Similarly, when the partition plate 12 inside the transmission groove 11 at the upper end of the reagent feed port 5 is reset, the driven gear 10 on one side of the reagent feed port 5 is in a stationary state, and the other side is in a stationary state. The partition plate 12 inside the transmission slot 11 at the upper end of the sample feed port 6 at the end is driven to rotate by the rotation of the driven gear 10 on the same side to cooperate with the fixing part 13, so that the sample is discharged, so that the feeding can be realized separately, and the forward and reverse rotation of the servo motor 7 is controlled, so as to control the need for a certain material to carry out the material, so as to facilitate the addition of samples or reagents according to specific circumstances, and the transmission rod 8 can drive the rotating rod 16 to rotate when it rotates, so that the linkage sleeve 17, the mixing blade 18, and the mixing cover 19 at the upper end of the rotating rod 16 can all perform circular motion synchronously, so as to fully mix the sample and the reagent, and the mixing blade 18 is a new type of blade, which can improve the mixing effect through the special arc shape and its own shape, and the mixed material can be discharged through the discharge port 15 after mixing to carry out subsequent work;When the servo motor 7 is running, vibration will be generated. In order to prevent the vibration from affecting other functions of the chemiluminescence immunoassay analyzer body 2, shock-absorbing plates 25 are provided at both ends of the mixing box 3. When vibrating, the slide groove 24 inside the shock-absorbing plate 25 and the slider 23 in the slide groove 24 can slide. Through the hinged cooperation of the hinged rod 21 and the hinged seat 20, the hinged rod 21 and the shock-absorbing plate 25 bear a part of the force, and a buffer spring 22 is provided between the hinged rod 21 and the hinged rod 21. Through the characteristics of the spring, the vibration of the servo motor 7 can also be fully unloaded, so as to protect the remaining parts of the chemiluminescence immunoassay analyzer body 2. Since the utility model is provided with a mixing mechanism, through the transmission cooperation between the gears and the design of the partition plate 12, it can realize the automatic feeding control of reagents or samples, can reduce manual operation, improve work efficiency, and in some occasions requiring repetitive operations, it can ensure the consistency and accuracy of the operation, and by controlling the forward and reverse rotation of the servo motor 7, it can accurately The feeding amount and speed of the reagent or sample can be controlled. When the transmission rod 8 rotates, the rotating rod 16 is driven to perform circular motion, so that the mixing blades 18, the mixing cover 19 and other components are mixed synchronously, and the samples and reagents can be fully mixed to improve the mixing effect and product quality. Because the damping mechanism is provided, the setting of the damping plate 25, the slide groove 24 and the slider 23 can effectively reduce the vibration generated by the servo motor 7 from being transmitted to other functional components of the chemiluminescence immunoassay body 2, and protect the stability and accuracy of the instrument. Through the design of the hinge rod 21 and the buffer spring 22, part of the vibration force can be transferred to the damping plate 25, and through the buffering effect of the spring, the influence of the vibration on the instrument body can be further reduced, the service life of the instrument can be extended, the influence of the vibration on the instrument can be reduced, and the stability and accuracy of the instrument can be maintained, and the test results of the chemiluminescence immunoassay can be ensured to be accurate and reliable. The utility model relates to a chemiluminescence immunoassay, which is simple and reasonable in structure design and convenient and quick to use. ;

[0021] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A chemiluminescent immunoassay analyzer, comprising a base (1), a mixing mechanism and a shock absorbing mechanism, characterized in that: The upper end of the base (1) is provided with a chemiluminescent immunoassay analyzer body (2), a mixing box (3) is provided inside the chemiluminescent immunoassay analyzer body (2), the upper end of the mixing box (3) is movably connected with a cover plate (4), one end of the upper end surface of the cover plate (4) is provided with a reagent feed port (5), the other end of the upper end surface of the cover plate (4) is provided with a sample feed port (6), a servo motor (7) is provided at the center of the cover plate (4), a mixing mechanism is provided at the bottom end of the servo motor (7), and shock absorbing mechanisms are provided at both left and right ends of the mixing box (3).

2. A chemiluminescent immunoassay analyzer according to claim 1, characterized in that: The mixing mechanism comprises a transmission rod (8), an incomplete gear (9), a driven gear (10), a transmission trough (11), a partition plate (12), a fixing member (13), a connecting rod (14), a material outlet (15), a rotating rod (16), a linkage sleeve (17), a mixing blade (18), and a mixing cover (19); the bottom end of the servo motor (7) is fixedly connected to the transmission rod (8), and the upper end of the transmission rod (8) is fixedly connected to the incomplete gear (9).

3. A chemiluminescent immunoassay analyzer according to claim 2, characterized in that: The left and right ends of the incomplete gear (9) are provided with driven gears (10), the bottom ends of the driven gears (10) are provided with connecting rods (14), the connecting rods (14) are movably connected to the mixing box (3), the outer walls of the reagent feed port (5) and the sample feed port (6) are provided with transmission grooves (11), the transmission grooves (11) are movably connected with partition plates (12), the upper end surfaces of the driven gears (10) are fixedly connected with fixing members (13), and the fixing members (13) are fixedly connected to the partition plates (12) on the same side.

4. A chemiluminescent immunoassay analyzer according to claim 2, characterized in that: The transmission rod (8) is sleeve-connected to the mixing box (3); the bottom end of the transmission rod (8) is fixedly connected to a rotating rod (16); the outer wall of the rotating rod (16) is provided with a plurality of linkage sleeves (17); the outer walls of the linkage sleeves (17) are each fixedly connected to a plurality of mixing blades (18); and the other ends of the mixing blades (18) are each fixedly connected to a mixing cover (19).

5. A chemiluminescent immunoassay analyzer according to claim 1, characterized in that: The shock absorbing mechanism comprises an articulated seat (20), an articulated rod (21), a buffer spring (22), a slider (23), a slide groove (24), and a shock absorbing plate (25). The side walls at both ends of the mixing box (3) are provided with a shock absorbing plate (25), and the other end of the shock absorbing plate (25) is provided with a slide groove (24), and a pair of sliders (23) are slidably connected in the slide groove (24).

6. A chemiluminescent immunoassay analyzer according to claim 5, characterized in that: The other ends of the sliders (23) are fixedly connected to hinged rods (21), the other ends of the hinged rods (21) are hinged to hinged seats (20), the hinged seats (20) are fixedly connected to the inner wall of the chemiluminescence immunoassay analyzer body (2), and buffer springs (22) are fixedly connected between the hinged rods (21) on the same side and the hinged rods (21).

7. A chemiluminescent immunoassay analyzer according to claim 3, characterized in that: The incomplete gear (9) is meshed with the driven gear (10).