Tinipalase and carrier mixing equipment
By designing a tenaprose and carrier mixing equipment containing stirring and filtration functions, the problem that existing equipment cannot filtration during mixing and unloading is solved, and efficient filtration and purity improvement of the mixed liquid are achieved.
Patent Information
- Application Number
- CN202421849640.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-01
- Publication Date
- 2025-05-09
- Estimated Expiration
- 2034-08-01
AI Technical Summary
The existing tenaprose and carrier mixing equipment cannot perform filtration operations during the mixing and unloading process, resulting in the mixture containing more large particles of impurities, affecting the purity. The subsequent filtration steps require transportation and re-filtration, which is cumbersome.
A mixing device including a mixing cylinder, a mixing motor, a mixing shaft, a mixing blade, an electric heater and a filter assembly is designed. The filter assembly includes a filter box, a microporous membrane and a curved mesh cover, through which the filtering operation of the mixture is achieved.
The filtration of the mixed liquid during the mixing and unloading process is realized, the purity of the mixed liquid is improved, the operation process is simplified, and the tedious steps of subsequent transportation and re-filtration are avoided.
Smart Images
Figure CN222841862U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of drug mixing equipment, in particular to a mixing equipment for tenecteplase and a carrier. Background Art
[0002] Tenaplase is an important anticoagulant drug, which is widely used in the treatment of vascular diseases such as acute myocardial infarction, pulmonary embolism, acute ischemic stroke and deep vein thrombosis. In the drug production process, tenaplase needs to be mixed with a specific carrier to make the final product. When mixing tenaplase and the carrier, the corresponding mixing equipment is usually used. There are many types of mixing equipment on the market, and most of the mixing equipment uses motors to drive the corresponding stirring blades to rotate to achieve the mixing operation.
[0003] However, when this type of mixing device is used, it can only perform mixing operations, and cannot filter the stock solution during the mixing and unloading process, and cannot achieve the effect of filtration and purification. It is easy to cause the mixed liquid to contain more large particles of impurities, affecting its purity. If a subsequent filtration step is added, it is necessary to transport and re-filter, which is relatively cumbersome and inconvenient for users. In view of this, we propose a mixing device for tenaplase and a carrier. Utility Model Content
[0004] The purpose of the utility model is to provide a device for mixing tenecteplase and a carrier, so as to solve the defects mentioned in the above background technology.
[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:
[0006] A device for mixing tenaplase and a carrier comprises a mixing cylinder, a conical bucket is fixedly mounted on the bottom end of the mixing cylinder, a discharge pipe is fixedly mounted on the bottom end of the conical bucket, a discharge pipe is fixedly mounted on the discharge valve, a discharge hose is fixedly mounted on the bottom end of the discharge pipe, a filter assembly is arranged below the discharge hose, the filter assembly comprises a filter box, a top cover is hinged on the top surface of the filter box by a hinge, the bottom end of the discharge hose is fixedly mounted on the top cover, support bars are fixedly mounted on the left and right inner walls of the filter box, an arc-shaped mesh cover is arranged in the filter box, carrying plates are fixedly mounted on both ends of the arc-shaped mesh cover, the carrying plates are abutted on the upper surface of the support bars, and a microporous membrane is arranged on the inner wall of the arc-shaped mesh cover.
[0007] Preferably, a conical cylinder is fixedly mounted on the bottom end of the filter box, and an external discharge pipe is fixedly mounted on the bottom end of the conical cylinder.
[0008] Preferably, the outer row pipe is arranged vertically downward, and the planes where the inner walls of the conical bucket and the conical cylinder are located are arranged to be inclined downward by 45° to 60°.
[0009] Preferably, an electric heater is fixedly mounted on the barrel of the mixing barrel, and the wall thickness of the mixing barrel is 0.3 cm to 0.5 cm.
[0010] Preferably, a sealing cover is fixedly mounted on the top surface of the mixing cylinder, and a raw material adding tube is fixedly mounted on the sealing cover.
[0011] Preferably, the bottom end of the discharge hose is fixedly mounted at the center of the top cover, and the microporous membrane is located directly below the end tube body of the discharge hose.
[0012] Preferably, the arc-shaped mesh cover is a mesh-like structure, and the cross-sections of the arc-shaped mesh cover and the microporous membrane are both semicircular.
[0013] Preferably, a stirring motor is fixedly mounted at the center of the upper surface of the sealing cover, a vertically arranged stirring shaft is fixedly mounted at the end of the output shaft of the stirring motor, a stirring blade is fixedly mounted on the stirring shaft, and the stirring blade is located in the mixing barrel.
[0014] Compared with the prior art, the beneficial effects of the utility model are:
[0015] 1. The utility model is provided with a mixing drum, and a stirring motor, a stirring shaft and a stirring blade are arranged on the mixing drum, so that when in use, the stirring motor can be used to drive the stirring shaft and the stirring blade to rotate, thereby realizing the mixing operation. In addition, the electric heater is provided to achieve the effect of heating, thereby achieving the effect of facilitating mixing and heating.
[0016] 2. The utility model can filter the mixed liquid by using a microporous membrane through the filter assembly, which is helpful to improve the purity after filtering. In addition, the arc-shaped mesh cover and the microporous membrane can be taken out for easy cleaning. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;
[0018] Figure 2 It is a partial structural schematic diagram of the utility model;
[0019] Figure 3 This is a schematic diagram of the structure of the filter assembly of the utility model;
[0020] Figure 4 This is a schematic diagram of the explosion structure of the filter assembly of the utility model;
[0021] The meaning of each number in the figure is:
[0022] 1. Mixing cylinder; 10. Conical bucket; 11. Discharge pipe; 111. Discharge hose; 12. Discharge valve; 13. Electric heater; 14. Sealing cover; 15. Raw material adding pipe;
[0023] 2. Stirring motor; 20. Stirring shaft; 21. Stirring blade;
[0024] 3. Filter assembly; 30. Filter box; 301. Support bar; 31. Conical cylinder; 32. External discharge pipe; 33. Top cover; 34. Arc mesh cover; 35. Microporous membrane; 36. Mounting plate. DETAILED DESCRIPTION
[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0026] See also Figure 1-Figure 4 The utility model provides a technical solution: a device for mixing tenaplase and a carrier, comprising a mixing drum 1, a conical bucket 10 is fixedly installed at the bottom end of the mixing drum 1, a discharge pipe 11 is fixedly installed at the bottom end of the conical bucket 10, a discharge valve 12 is fixedly installed on the discharge pipe 11, a discharge hose 111 is fixedly installed at the bottom end of the discharge pipe 11, a filter assembly 3 is arranged below the discharge hose 111, the filter assembly 3 comprises a filter box 30, a top cover 33 is hinged on the top surface of the filter box 30 through a hinge, and the bottom end of the discharge hose 111 is fixedly installed on the top cover 33, so that the top cover 33 can be normally opened for cleaning operation;
[0027] Specifically, support bars 301 are fixedly installed on the inner walls on the left and right sides of the filter box 30, an arc-shaped mesh cover 34 is arranged in the filter box 30, and mounting plates 36 are fixedly installed on both ends of the arc-shaped mesh cover 34. The mounting plates 36 are against the upper surface of the support bars 301, and a microporous membrane 35 is arranged on the inner wall of the arc-shaped mesh cover 34. The microporous membrane is a semi-permeable membrane used for filtration, and its main function is to separate polymer colloids or suspended particles of a certain size from the solution, so as to achieve the effect of filtration and separation and purification.
[0028] In this embodiment, the top cover 33 is fixedly connected to the top surface of the filter box 30 by a plurality of fastening bolts, and the side surface of the top cover 33 is tightly fitted to the top surface of the filter box 30 to ensure a sealing effect. After the fastening bolts on the top cover 33 are subsequently unscrewed, the top cover 33 can be opened normally along the hinge portion thereon.
[0029] Specifically, a conical cylinder 31 is fixedly installed at the bottom end of the filter box 30, and an external discharge pipe 32 is fixedly installed at the bottom end of the conical cylinder 31 to discharge the filtered solution to the outside.
[0030] Furthermore, the outer discharge pipe 32 is arranged vertically downward, and the planes where the inner walls of the conical bucket 10 and the conical cylinder 31 are located are arranged to be inclined downward by 45° to 60°, so that the unloading is smoother.
[0031] In addition, an electric heater 13 is fixedly mounted on the body of the mixing cylinder 1 . The wall thickness of the mixing cylinder 1 is 0.3 cm to 0.5 cm, so that when the electric heater 13 is heated, the heat can be better transferred to the interior of the mixing cylinder 1 .
[0032] It is worth noting that a sealing cover 14 is fixedly mounted on the top surface of the mixing barrel 1 , and a raw material adding pipe 15 is fixedly mounted on the sealing cover 14 , so that the raw material adding operation can be performed along the raw material adding pipe 15 .
[0033] In this embodiment, the bottom end of the discharge hose 111 is fixedly installed at the center position of the top cover 33, and the microporous membrane 35 is located directly below the end tube body of the discharge hose 111, so that the mixed liquid discharged along the discharge hose 111 can better drip onto the microporous membrane 35 for filtering operation; the arc-shaped mesh cover 34 is a mesh structure, and the cross-sections of the arc-shaped mesh cover 34 and the microporous membrane 35 are both semicircular, which is conducive to increasing the filtering area and making the filtering of the mixed liquid faster.
[0034] It is worth noting that a stirring motor 2 is fixedly installed at the center position of the upper surface of the sealing cover 14, and a vertically arranged stirring shaft 20 is fixedly installed at the end of the output shaft of the stirring motor 2. A stirring blade 21 is fixedly installed on the stirring shaft 20, and the stirring blade 21 is located in the mixing barrel 1, so that the stirring motor 2 is utilized to drive the stirring shaft 20 and the stirring blade 21 to rotate, thereby performing stirring and mixing operations.
[0035] When the tenaplase and carrier mixing device of the utility model is used, the discharge valve 12 is closed, the raw materials are added into the mixing barrel 1 along the raw material adding pipe 15, the electric heater 13 is connected to the external power supply and made to work, the electric heater 13 works and starts heating, and in addition, the stirring motor 2 is connected to the external power supply and made to work, the stirring motor 2 works, the output shaft thereon rotates to drive the stirring shaft 20 and the stirring blade 21 to rotate, and the stirring and mixing operation is realized. After the mixing is completed, the discharge valve 12 is opened, and the mixed liquid enters the filter box 30 along the discharge hose 111 at this time, and the mixed liquid is filtered through the microporous membrane 35 and then discharged outward along the conical barrel 31 and the outer discharge pipe 32, and the particulate impurities are blocked on the microporous membrane 35. After the filtration is completed, the top cover 33 is opened, and the arc mesh cover 34 and the microporous membrane 35 are taken out for cleaning operation.
[0036] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the utility model and are not used to limit the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection of the utility model is defined by the attached claims and their equivalents.
Claims
1. A device for mixing tenecteplase and a carrier, comprising a mixing cylinder (1), characterized in that: A conical bucket (10) is fixedly mounted on the bottom end of the mixing barrel (1), a discharge pipe (11) is fixedly mounted on the bottom end of the conical bucket (10), a discharge valve (12) is fixedly mounted on the discharge pipe (11), a discharge hose (111) is fixedly mounted on the bottom end of the discharge pipe (11), a filter assembly (3) is arranged below the discharge hose (111), the filter assembly (3) comprises a filter box (30), a top cover (33) is hingedly connected to the top surface of the filter box (30) via a hinge ), the bottom end of the discharge hose (111) is fixedly mounted on the top cover (33), support bars (301) are fixedly mounted on the inner walls on both sides of the left and right sides of the filter box (30), an arc-shaped mesh cover (34) is arranged in the filter box (30), and supporting plates (36) are fixedly mounted on both ends of the arc-shaped mesh cover (34), the supporting plates (36) are against the upper surface of the support bars (301), and a microporous membrane (35) is arranged on the inner wall of the arc-shaped mesh cover (34).
2. The device for mixing tenecteplase and a carrier according to claim 1, characterized in that: A conical cylinder (31) is fixedly mounted on the bottom end of the filter box (30), and an external discharge pipe (32) is fixedly mounted on the bottom end of the conical cylinder (31).
3. The device for mixing tenecteplase and a carrier according to claim 2, characterized in that: The outer pipe (32) is arranged vertically downward, and the planes on which the inner walls of the conical bucket (10) and the conical cylinder (31) are located are both arranged to be inclined downward at 45° to 60°.
4. The device for mixing tenecteplase and a carrier according to claim 1, characterized in that: An electric heater (13) is fixedly mounted on the body of the mixing cylinder (1); the wall thickness of the mixing cylinder (1) is 0.3 cm to 0.5 cm.
5. The device for mixing tenecteplase and a carrier according to claim 1, characterized in that: A sealing cover (14) is fixedly mounted on the top surface of the mixing cylinder (1), and a raw material adding tube (15) is fixedly mounted on the sealing cover (14).
6. The device for mixing tenecteplase and a carrier according to claim 1, characterized in that: The bottom end of the discharge hose (111) is fixedly mounted at the center of the top cover (33), and the microporous membrane (35) is located directly below the end tube body of the discharge hose (111).
7. The device for mixing tenecteplase and a carrier according to claim 1, characterized in that: The arc-shaped mesh cover (34) is a mesh-like structure, and the cross-sections of the arc-shaped mesh cover (34) and the microporous membrane (35) are both semicircular.
8. The device for mixing tenecteplase and a carrier according to claim 5, characterized in that: A stirring motor (2) is fixedly mounted at the center of the upper surface of the sealing cover (14); a stirring shaft (20) arranged vertically is fixedly mounted at the end of the output shaft of the stirring motor (2); a stirring blade (21) is fixedly mounted on the stirring shaft (20); and the stirring blade (21) is located in the mixing barrel (1).