Preparation device for fluorouracil raw material

Abstract

The utility model relates to the technical field of chemical production, and discloses a fluorouracil raw material preparation device which comprises a raw material preparation barrel and a second preparation mechanism, the inner wall of the raw material preparation barrel is sleeved with a conversion outer wall, the inner wall of the conversion outer wall is sleeved with an annular cooling pipe, the inner wall of the annular cooling pipe is sleeved with an inner stirring partition plate, and the inner stirring partition plate is sleeved with an outer stirring partition plate. A plurality of material mixing grooves are fixedly connected to the inner wall of the internal stirring partition plate and are distributed on the inner wall of the internal stirring partition plate in a circumferential array shape. According to the fluorouracil raw material preparation device, the first preparation mechanism, the second preparation mechanism and the third preparation mechanism are arranged in the equipment, so that the equipment can directly prepare a fluorouracil raw material step by step, and an impurity precipitation plate and a draining pipe are arranged in the equipment, so that the equipment can discharge redundant impurity particles; the influence of redundant impurities on the preparation efficiency of the fluorouracil raw material can also be effectively avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of chemical production, in particular to a fluorouracil raw material preparation device. Background Art

[0002] Fluorocytosine, also known as 5-fluorocytosine, Anquzhi, 5-fluorocytidine, Anrapon, etc., CAS No. 2022-85-7, is a white to white crystalline solid powder. It is a chemical product with high added value in the field of fluorine-containing fine chemicals. Fluorocytosine is used to treat fungal infections caused by cryptococcus and Candida, such as fungal sepsis, endocarditis, meningitis, and antifungal drugs for lung and urinary tract infections. It is mainly used for skin and mucosal candidiasis, Candida endocarditis, Candida arthritis, cryptococcal meningitis and chromomycosis.

[0003] The existing preparation container cannot discharge the excess raw materials in the preparation process of flucytosine in this process, which causes the speed of each link in the flucytosine preparation process to be slow and the purity of the flucytosine preparation to be reduced. The current equipment can only be operated step by step, which increases the overall preparation time. Therefore, a fluorouracil raw material preparation device is proposed. Utility Model Content

[0004] The utility model provides the following technical solution: a fluorouracil raw material preparation device, comprising a raw material preparation barrel and a second preparation mechanism, the inner wall of the raw material preparation barrel is sleeved with a conversion outer wall, the inner wall of the conversion outer wall is sleeved with an annular cooling pipe, the inner wall of the annular cooling pipe is sleeved with an internal stirring baffle, the inner wall of the internal stirring baffle is fixedly connected with a plurality of mixing troughs, the plurality of mixing troughs are distributed in a circular array on the inner wall of the internal stirring baffle, the inner wall of the raw material preparation barrel is sleeved with a driving shaft, the outer wall of the driving shaft is sleeved with a stirring drum sleeve, the outer wall of the stirring drum sleeve is sleeved with a stirring rod, and the stirring rod is distributed in a circular array on the outer wall of the stirring drum sleeve.

[0005] As a preferred technical solution of the utility model, the outer wall of the raw material preparation barrel is provided with a top closing cover, the outer wall of the top closing cover is fixedly connected to a cover handle, the top of the raw material preparation barrel is provided with a driving motor, the outer wall of the top closing cover is fixedly connected to a water inlet pipe, the outer wall of the top closing cover is fixedly connected to a feed pipe, the inner wall of the raw material preparation barrel is sleeved with a first preparation mechanism, and the inner wall of the raw material preparation barrel is sleeved with a third preparation mechanism.

[0006] As a preferred technical solution of the utility model, the inner wall of the third preparation mechanism is sleeved with a partition mesh cover, the inner wall of the first preparation mechanism is fixedly connected with an impurity precipitation plate, and the inner wall of the partition mesh cover is sleeved with a material throwing mechanism.

[0007] As a preferred technical solution of the utility model, the driving shaft is fixedly connected with a material throwing plate on the side away from the driving motor, the outer wall of the material throwing plate is provided with a mounting plate, the inner wall of the mounting plate is fixedly connected with a drain pipe, and the mounting plates are distributed in a circular array on the inner wall of the material throwing plate.

[0008] As a preferred technical solution of the utility model, the bottom of the raw material preparation barrel is fixedly connected with a supporting barrel seat, the number of the supporting barrel seats is four, and the supporting barrel seats are symmetrically distributed on the bottom of the raw material preparation barrel.

[0009] As a preferred technical solution of the utility model, a single-chip microcomputer controller is fixedly connected to the outer wall of the raw material preparation barrel, and the drive motor is electrically connected to the single-chip microcomputer controller.

[0010] As a preferred technical solution of the utility model, the outer wall of the annular cooling tube is fixedly connected with a nitrogen exhaust port, the outer wall of the annular cooling tube is fixedly connected with a nitrogen inlet, and the raw material preparation barrel is fixedly connected with an exhaust pipe on the side away from the nitrogen inlet.

[0011] Compared with the prior art, the utility model has the following beneficial effects:

[0012] 1. The fluorouracil raw material preparation device, by arranging the first preparation mechanism, the second preparation mechanism and the third preparation mechanism inside the device, enables the device to directly prepare the fluorouracil raw material step by step, and arranges the impurity precipitation plate and the drain pipe inside the device, so that the device can discharge the excess impurity particles, and can also effectively avoid the excess impurities from affecting the preparation efficiency of the fluorouracil raw material.

[0013] 2. The fluorouracil raw material preparation device is provided with a partition mesh cover and a third preparation mechanism inside the device, so that when the device discharges the fluorouracil raw material, unpurified impurities in the fluorouracil raw material are not easily discharged from the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the three-dimensional structure of a fluorouracil raw material preparation device;

[0015] Figure 2 It is a structural schematic diagram of a first preparation mechanism in a fluorouracil raw material preparation device;

[0016] Figure 3 It is a structural schematic diagram of the third preparation mechanism in a fluorouracil raw material preparation device;

[0017] Figure 4 It is a structural schematic diagram of a second preparation mechanism in a fluorouracil raw material preparation device;

[0018] Figure 5 The present invention is a structural schematic diagram of a material throwing mechanism in a fluorouracil raw material preparation device.

[0019] In the figure: 1. raw material preparation barrel; 2. supporting barrel seat; 3. single-chip microcomputer controller; 4. top closing cover; 5. cover handle; 6. driving motor; 7. water inlet pipe; 8. feeding pipe; 9. nitrogen exhaust port; 10. nitrogen inlet port; 11. exhaust pipe; 12. first preparation mechanism; 13. impurity precipitation plate; 14. second preparation mechanism; 141. conversion outer wall; 142. annular cooling pipe; 143. internal stirring baffle; 144. stirring drum sleeve; 145. stirring rod; 146. mixing trough; 15. third preparation mechanism; 16. driving shaft; 17. partition mesh cover; 18. material throwing mechanism; 181. material throwing plate; 182. mounting plate; 183. drain pipe. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] See also Figure 1-5A fluorouracil raw material preparation device comprises a raw material preparation barrel 1 and a second preparation mechanism 14, wherein the inner wall of the raw material preparation barrel 1 is sleeved with a conversion outer wall 141, the inner wall of the conversion outer wall 141 is sleeved with an annular cooling pipe 142, the inner wall of the annular cooling pipe 142 is sleeved with an internal stirring baffle 143, the inner wall of the internal stirring baffle 143 is fixedly connected with a plurality of mixing troughs 146, the plurality of mixing troughs 146 are distributed in a circular array on the inner wall of the internal stirring baffle 143, the inner wall of the raw material preparation barrel 1 is sleeved with a driving shaft 16, the outer wall of the driving shaft 16 is sleeved with a stirring drum sleeve 144, the outer wall of the stirring drum sleeve 144 is sleeved with a stirring rod 145, the stirring rod 145 is distributed in a circular array on the outer wall of the stirring drum sleeve 144, the annular cooling pipe 1 The outer wall of the raw material preparation barrel 1 is fixedly connected with a nitrogen exhaust port 9, the outer wall of the annular cooling pipe 142 is fixedly connected with a nitrogen inlet 10, and the raw material preparation barrel 1 is fixedly connected with an exhaust pipe 11 on the side away from the nitrogen inlet 10, wherein the solution to be cooled and purified will be cooled by the annular cooling pipe 142, and the solution stored in the internal stirring baffle 143 will be stirred and purified by the stirring rod 145, and a mixing tank 146 is arranged in the internal stirring baffle 143, so that the purification efficiency of the equipment can be improved, the outer wall of the raw material preparation barrel 1 is provided with a top closing cover 4, the outer wall of the top closing cover 4 is fixedly connected with a cover plate handle 5, the top of the raw material preparation barrel 1 is provided with a driving motor 6, the outer wall of the top closing cover 4 is fixedly connected with a water inlet pipe 7, and the outer wall of the top closing cover 4 is fixedly connected with a water inlet pipe 7. A feed pipe 8 is connected, a first preparation mechanism 12 is sleeved on the inner wall of the raw material preparation barrel 1, and a third preparation mechanism 15 is sleeved on the inner wall of the raw material preparation barrel 1, wherein the fluorouracil raw material entering the equipment will be directly stored in the first preparation mechanism 12, and the fluorouracil raw material diluted by water will be filtered by the impurity precipitation plate 13, so that the impurities in the fluorouracil raw material can be preliminarily filtered and separated by the impurity precipitation plate 13, and the inner wall of the third preparation mechanism 15 is sleeved with a partition mesh cover 17, and the inner wall of the first preparation mechanism 12 is fixedly connected to the impurity precipitation plate 13, and the inner wall of the partition mesh cover 17 is sleeved with a material throwing mechanism 18, wherein the partition mesh cover 17 can screen out the impurities in the raw material, thereby improving the purification efficiency of the equipment and driving The driving shaft 16 is fixedly connected with a material throwing plate 181 on the side away from the driving motor 6. The outer wall of the material throwing plate 181 is provided with a mounting plate 182. The inner wall of the mounting plate 182 is fixedly connected with a drain pipe 183, and the mounting plates 182 are distributed in a circular array on the inner wall of the material throwing plate 181, wherein the solution will directly sit in the drain pipe 183 after being purified, so that it can be finally purified and filtered, and the mounting plate 182 can prevent the raw material solution from scattering. The bottom of the raw material preparation barrel 1 is fixedly connected with a supporting barrel seat 2. The number of the supporting barrel seats 2 is four, and the supporting barrel seats 2 are symmetrically distributed at the bottom of the raw material preparation barrel 1, wherein the supporting barrel seat 2 can provide a stable supporting force for the equipment when the equipment is working, and can be used when the equipment is working.It can effectively prevent equipment damage. The outer wall of the raw material preparation barrel 1 is fixedly connected with a single-chip controller 3, and the drive motor 6 is electrically connected to the single-chip controller 3. The control chip in the single-chip controller 3 can directly control the chip in the drive motor 6, so that the operator can control the equipment by pressing the single-chip controller 3.

[0022] Working principle: when the equipment needs to be used, the operator starts the equipment through the single-chip controller 3, and then pours the fluorouracil raw material preparation into the equipment through the feed pipe 8, and pours water into the equipment through the water inlet pipe 7, so that the fluorouracil raw material preparation can be initially filtered on the impurity precipitation plate 13, and then the raw material will enter the internal stirring baffle 143, and under the action of the driving motor 6 driving the driving shaft 16, the driving shaft 16 can drive the stirring rod 145 to stir the fluorouracil raw material preparation, and then it will fall into the drain pipe 183, and finally the purified solution will be discharged through the exhaust pipe 11.

[0023] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A fluorouracil raw material preparation device, comprising a raw material preparation barrel (1) and a second preparation mechanism (14), characterized in that: The inner wall of the raw material preparation barrel (1) is sleeved with a conversion outer wall (141), the inner wall of the conversion outer wall (141) is sleeved with an annular cooling tube (142), the inner wall of the annular cooling tube (142) is sleeved with an internal stirring baffle (143), the inner wall of the internal stirring baffle (143) is fixedly connected with a plurality of mixing troughs (146), the plurality of mixing troughs (146) are distributed in a circular array on the inner wall of the internal stirring baffle (143), the inner wall of the raw material preparation barrel (1) is sleeved with a driving shaft (16), the outer wall of the driving shaft (16) is sleeved with a stirring drum sleeve (144), the outer wall of the stirring drum sleeve (144) is sleeved with a stirring rod (145), the stirring rod (145) is distributed in a circular array on the outer wall of the stirring drum sleeve (144).

2. A fluorouracil raw material preparation device according to claim 1, characterized in that: The outer wall of the raw material preparation barrel (1) is provided with a top closing cover (4), the outer wall of the top closing cover (4) is fixedly connected to a cover plate handle (5), the top of the raw material preparation barrel (1) is provided with a driving motor (6), the outer wall of the top closing cover (4) is fixedly connected to a water inlet pipe (7), the outer wall of the top closing cover (4) is fixedly connected to a feed pipe (8), the inner wall of the raw material preparation barrel (1) is sleeved with a first preparation mechanism (12), and the inner wall of the raw material preparation barrel (1) is sleeved with a third preparation mechanism (15).

3. A fluorouracil raw material preparation device according to claim 2, characterized in that: The inner wall of the third preparation mechanism (15) is sleeved with a partition mesh cover (17), the inner wall of the first preparation mechanism (12) is fixedly connected with an impurity precipitation plate (13), and the inner wall of the partition mesh cover (17) is sleeved with a material throwing mechanism (18).

4. A fluorouracil raw material preparation device according to claim 3, characterized in that: The driving shaft (16) is fixedly connected to a material throwing plate (181) on the side away from the driving motor (6); the outer wall of the material throwing plate (181) is provided with a mounting plate (182); the inner wall of the mounting plate (182) is fixedly connected to a drain pipe (183); and the mounting plates (182) are distributed in a circular array on the inner wall of the material throwing plate (181).

5. The device for preparing fluorouracil raw materials according to claim 1, characterized in that: The bottom of the raw material preparation barrel (1) is fixedly connected to a supporting barrel seat (2), the number of the supporting barrel seats (2) is four, and the supporting barrel seats (2) are symmetrically distributed at the bottom of the raw material preparation barrel (1).

6. A fluorouracil raw material preparation device according to claim 2, characterized in that: A single-chip microcomputer controller (3) is fixedly connected to the outer wall of the raw material preparation barrel (1), and the drive motor (6) is electrically connected to the single-chip microcomputer controller (3).

7. The device for preparing fluorouracil raw materials according to claim 1, characterized in that: The outer wall of the annular cooling tube (142) is fixedly connected with a nitrogen exhaust port (9), the outer wall of the annular cooling tube (142) is fixedly connected with a nitrogen inlet (10), and the raw material preparation barrel (1) is fixedly connected with an exhaust pipe (11) on a side away from the nitrogen inlet (10).

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