Concentrated sulfuric acid dropping device

Abstract

The utility model relates to the field of pharmacy, and discloses a concentrated sulfuric acid dropwise adding device which can be used for quantitatively dropwise adding concentrated sulfuric acid into a reaction kettle at a constant speed in the production process, so that medicines are fully mixed and uniformly proportioned, and an optimal effect is achieved. The device comprises a funnel, a needle valve, a glass view cup and a flow guide tube. The funnel, the needle valve, the glass view cup and the flow guide pipe are sequentially connected from top to bottom, the funnel is configured to contain and temporarily store concentrated sulfuric acid and convey the concentrated sulfuric acid to the needle valve at the lower end, the needle valve is configured to adjust the flow speed of the concentrated sulfuric acid, and the side wall of the glass view cup is a surrounding transparent window. The glass view cup is configured to observe the dripping speed of concentrated sulfuric acid through the window and confirm whether dripping of the concentrated sulfuric acid is completed, and the flow guide pipe is configured to guide the flow direction of the concentrated sulfuric acid so as to prevent the concentrated sulfuric acid from dripping on the container wall at the lower end.

Description

Technical Field

[0001] The present application relates to the pharmaceutical field, and in particular to a concentrated sulfuric acid dropping device. Background Art

[0002] In the pharmaceutical industry, compliance with Good Manufacturing Practice (GMP) is the key to ensuring drug quality and safety. GMP standards cover the entire production chain from raw material procurement, production process, quality control to final product distribution. Among them, on-site 5S management (sorting, organizing, cleaning, cleaning, and literacy) is the basis for achieving GMP requirements and is essential for maintaining a clean, orderly, and efficient production environment.

[0003] In the traditional pharmaceutical production process, the processing and mixing of raw materials is one of the key steps that affect product quality. Take the use of concentrated sulfuric acid as an example. It is one of the essential raw materials in the production of many chemical synthetic drugs. The existing technology is to directly pour concentrated sulfuric acid into the reactor before production. However, this practice has many potential problems and challenges:

[0004] 1. Uneven stirring: Direct addition of concentrated sulfuric acid may result in uneven mixing with other raw materials. Due to the high density and viscosity of concentrated sulfuric acid, if it is not stirred sufficiently, areas of uneven concentration will be formed, affecting the uniformity of the chemical reaction and the quality of the final product.

[0005] 2. Uneven distribution of ingredients: Uneven mixing of concentrated sulfuric acid and other raw materials not only affects the efficiency of chemical reactions, but may also lead to uneven distribution of ingredients, which in turn affects the stability and effectiveness of the drug.

[0006] 3. Safety risks: Direct handling of concentrated sulfuric acid presents safety risks, including chemical burns and inhalation hazards. Uneven mixing may also lead to local overheating or runaway reactions, increasing the risk of accidents. Summary of the invention

[0007] The purpose of the present application is to provide a concentrated sulfuric acid dripping device, which can drip concentrated sulfuric acid into a reactor at a uniform speed and quantitatively during the production process, so that the drugs are fully mixed and the proportions are uniform, achieving the best effect.

[0008] The present application discloses a concentrated sulfuric acid dripping device, comprising: a funnel 1, a needle valve 2, a glass sight glass 3 and a flow guide tube 4;

[0009] The funnel 1, the needle valve 2, the glass sight glass 3 and the guide tube 4 are connected in sequence from top to bottom. The funnel 1 is configured to temporarily store concentrated sulfuric acid and transport the concentrated sulfuric acid to the needle valve 2 at the lower end. The needle valve 2 is configured to adjust the flow rate of the concentrated sulfuric acid. The side wall of the glass sight glass 3 is a surrounding transparent window 31. The glass sight glass 3 is configured to observe the dripping speed of the concentrated sulfuric acid and confirm whether the dripping of the concentrated sulfuric acid is completed through the window 31. The guide tube 4 is configured to guide the flow direction of the concentrated sulfuric acid to avoid the concentrated sulfuric acid dripping on the container wall at the lower end.

[0010] In a preferred example, the needle valve 2 includes a needle valve seat 21 and a needle valve stem 22, the first end of the needle valve seat 21 is connected to the lower end of the funnel 1, the second end of the needle valve seat 21 is connected to the upper end of the glass sight glass 3, the needle valve stem 22 is located on the side wall of the needle valve seat 21, and the needle valve 2 is configured to adjust the flow rate of the concentrated sulfuric acid flowing through the needle valve 2 by changing the opening size between the needle valve stem 22 and the needle valve seat 21.

[0011] In a preferred example, the first end of the needle valve stem 22 is needle-tip-shaped, and the second end of the needle valve stem 22 is provided with a handwheel 23, and the handwheel 23 is configured to rotate so that the needle valve stem 22 rotates along the axis to adjust the opening size between the first end of the needle valve stem 22 and the needle valve seat 21.

[0012] In a preferred example, a plurality of reinforcing strips 32 surround the outer side of the window 31 of the glass vision device 3, the upper and lower ends of the plurality of reinforcing strips 32 are connected to the upper cover and the lower cover of the glass vision device 3, the plurality of reinforcing strips 32 are parallel to the axis of the glass vision device 3, and the reinforcing strips 32 are configured to improve the mechanical strength of the glass vision device 3 and resist external impact.

[0013] In a preferred example, a sealing gasket is provided between the window 31 of the glass vision chamber 3 and the upper cover and the lower cover of the glass vision chamber 3, and the sealing gasket is configured to keep the glass vision chamber 3 in a sealed state to prevent leakage of the concentrated sulfuric acid.

[0014] In a preferred example, the inner wall of the upper end of the flow guide tube 4 is provided with an internal thread.

[0015] In a preferred example, the lower end of the glass sight glass 3 is provided with an external thread, and the external thread is cooperatively connected with the internal thread.

[0016] In a preferred example, the lower end of the flow guide tube 4 is a flange 5, and the flange 5 is configured to be connected to the reactor.

[0017] In a preferred example, the flange 5 is provided with a plurality of circumferentially arranged connection holes.

[0018] In a preferred example, it further includes a plurality of fastening screws, wherein the fastening screws pass through the connecting holes to connect the concentrated sulfuric acid dropping device to the reactor.

[0019] In the embodiment of the present application, the dripping device includes a funnel and a needle valve at the lower end of the funnel. The flow rate of the dripping liquid can be controlled by adjusting the opening size between the valve stem and the valve seat of the needle valve. The transparent window of the glass sight glass at the lower end of the needle valve can clearly help the experimenter see the dripping speed, so that the needle valve can be adjusted at any time, and it can also be confirmed whether the liquid in the funnel has been dripped. The guide tube at the lower end of the glass sight glass can prevent the liquid from dripping on the container wall. The overall structure of the device can effectively help to add materials at a uniform and slow speed, so that the drugs, reagents, etc. are fully mixed and reacted, eliminating the hidden danger of uneven mixing;

[0020] Furthermore, the second end of the valve stem of the needle valve is a hand wheel 23, which allows the experimenter to more conveniently rotate and adjust the opening size between the valve stem of the needle valve and the valve seat;

[0021] Furthermore, the outer side of the glass window is surrounded by multiple reinforcing strips, which can enhance the overall mechanical strength of the glass window and prevent impact.

[0022] Furthermore, by providing a sealing gasket at the connection between the window of the glass sight glass and the remaining components, liquid leakage during the dropping process can be effectively prevented.

[0023] A large number of technical features are recorded in the specification of this application, which are distributed in various technical solutions. If all possible combinations of technical features of this application (i.e., technical solutions) are to be listed, the specification will be too long. In order to avoid this problem, the various technical features disclosed in the above-mentioned invention content of this application, the various technical features disclosed in the various embodiments and examples below, and the various technical features disclosed in the accompanying drawings can be freely combined with each other to form various new technical solutions (these technical solutions are all deemed to have been recorded in this specification), unless the combination of such technical features is technically infeasible. For example, in one example, feature A+B+C is disclosed, and in another example, feature A+B+D+E is disclosed, and features C and D are equivalent technical means that play the same role. Technically, only one can be used, and it is impossible to use them at the same time. Feature E can be combined with feature C technically. Then, the solution of A+B+C+D should not be deemed to have been recorded because it is technically infeasible, and the solution of A+B+C+E should be deemed to have been recorded. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1It is a schematic structural diagram of a concentrated sulfuric acid dropping device according to one embodiment of the present application.

[0025] Description of reference numerals:

[0026] 1-funnel, 2-needle valve, 21, needle valve seat, 22-needle valve stem, 23-handwheel, 3-glass sight glass, 31-window, 32-reinforcement strip, 4-guide tube, 5-flange. DETAILED DESCRIPTION

[0027] In the following description, many technical details are provided to help readers better understand the present application. However, those skilled in the art can understand that the technical solution claimed in the present application can be implemented even without these technical details and various changes and modifications based on the following embodiments.

[0028] In order to make the objectives, technical solutions and advantages of the present application clearer, the implementation methods of the present application will be further described in detail below in conjunction with the accompanying drawings.

[0029] The present application relates to a concentrated sulfuric acid dropping device, the structure of which is shown in FIG. Figure 1 As shown, it includes: a funnel 1, a needle valve 2, a glass sight glass 3 and a guide tube 4;

[0030] The funnel 1, the needle valve 2, the glass sight glass 3 and the guide tube 4 are connected in sequence from top to bottom. The funnel 1 is configured to temporarily store concentrated sulfuric acid and transport the concentrated sulfuric acid to the needle valve 2 at the lower end. The needle valve 2 is configured to adjust the flow rate of the concentrated sulfuric acid. The side wall of the glass sight glass 3 is a surrounding transparent window 31. The glass sight glass 3 is configured to observe the dripping speed of the concentrated sulfuric acid through the window 31 and confirm whether the dripping of the concentrated sulfuric acid is complete. The guide tube 4 is configured to guide the flow direction of the concentrated sulfuric acid to avoid the concentrated sulfuric acid dripping on the container wall at the lower end.

[0031] In an optional embodiment, the needle valve 2 may include a needle valve seat 21 and a needle valve stem 22, the first end of the needle valve seat 21 is connected to the lower end of the funnel 1, the second end of the needle valve seat 21 is connected to the upper end of the glass sight glass 3, the needle valve stem 22 is located on the side wall of the needle valve seat 21, and the needle valve 2 is configured to adjust the flow rate of concentrated sulfuric acid flowing through the needle valve 2 by changing the opening size between the needle valve stem 22 and the needle valve seat 21.

[0032] In an optional embodiment, the first end of the needle valve stem 22 is needle-tip-shaped, and the second end of the needle valve stem 22 is provided with a handwheel 23, which is configured to rotate so that the needle valve stem 22 rotates along the axis to adjust the opening size between the first end of the needle valve stem 22 and the needle valve seat 21.

[0033] In an optional embodiment, a plurality of reinforcing strips 32 may be arranged around the outer side of the window 31 of the glass vision device 3, the upper and lower ends of the plurality of reinforcing strips 32 are connected to the upper cover and the lower cover of the glass vision device 3, the plurality of reinforcing strips 32 are parallel to the axis of the glass vision device 3, and the reinforcing strips 32 are configured to improve the mechanical strength of the glass vision device 3 and resist external impact.

[0034] In an optional embodiment, sealing gaskets are provided between the window 31 of the glass sight glass 3 and the upper cover and the lower cover of the glass sight glass 3, and the sealing gaskets are configured to keep the glass sight glass 3 in a sealed state to prevent leakage of concentrated sulfuric acid.

[0035] In an optional embodiment, the inner wall of the upper end of the flow guide tube 4 is provided with an internal thread.

[0036] In an optional embodiment, the lower end of the glass sight glass 3 is provided with an external thread, and the external thread is matched and connected with the internal thread.

[0037] In an optional embodiment, the lower end of the flow guide tube 4 is a flange 5, and the flange 5 is configured to be connected to the reactor.

[0038] In an optional embodiment, the flange 5 is provided with a plurality of circumferentially arranged connection holes.

[0039] In an optional embodiment, it further includes a plurality of fastening screws, which pass through the connecting holes to connect the concentrated sulfuric acid dropping device to the reaction kettle.

[0040] In order to better understand the technical solution of the present application, a specific example is provided below for illustration. The details listed in the example are mainly for ease of understanding and are not intended to limit the scope of protection of the present application.

[0041] During the production process, concentrated sulfuric acid is added to the funnel 1. If it is not necessary to drip concentrated sulfuric acid to the lower end at this time, the hand wheel 23 of the needle valve 2 can be rotated to close the needle valve 2, and the concentrated sulfuric acid is temporarily stored in the funnel 1. When it is necessary to drip concentrated sulfuric acid into the reactor below, the hand wheel 23 of the needle valve 2 is rotated to open the needle valve 2. If the dripping speed needs to be adjusted, the opening size between the needle valve stem 22 and the needle valve seat 21 can be adjusted by rotating the needle valve 2. During the dripping process, the experimenter can observe the dripping speed and whether the dripping is completed through the window 31 of the glass sight glass 3.

[0042] When installing the concentrated sulfuric acid dropping device, the flange 5 at the lower end of the concentrated sulfuric acid dropping device can be fixedly connected to the reactor by fastening screws. Since the guide pipe 4 of the concentrated sulfuric acid dropping device is located at the central axis of the flange 5, it can prevent the concentrated sulfuric acid from falling on the container wall when it is dropped.

[0043] It should be noted that in the application documents of this patent, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that the process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "including one" do not exclude the existence of other identical elements in the process, method, article or device including the elements. In the application documents of this patent, if it is mentioned that an action is performed according to an element, it means that the action is performed at least according to the element, which includes two situations: performing the action only according to the element, and performing the action according to the element and other elements. Expressions such as multiple, multiple, and multiple include 2, 2 times, 2 kinds, and more than 2, more than 2 times, and more than 2 kinds.

[0044] All documents mentioned in this application are considered to be included in the disclosure of this application as a whole, so that they can be used as the basis for modification when necessary. In addition, it should be understood that after reading the above disclosure of this application, those skilled in the art can make various changes or modifications to this application, and these equivalent forms also fall within the scope of protection claimed in this application.

Claims

1. A concentrated sulfuric acid dropping device, characterized in that, include: Funnel (1), needle valve (2), glass sight glass (3) and flow guide tube (4); The funnel (1), the needle valve (2), the glass sight glass (3) and the guide tube (4) are connected in sequence from top to bottom. The funnel (1) is configured to temporarily store concentrated sulfuric acid and to transport the concentrated sulfuric acid to the needle valve (2) at the lower end. The needle valve (2) is configured to adjust the flow rate of the concentrated sulfuric acid. The side wall of the glass sight glass (3) is a surrounding transparent window (31). The glass sight glass (3) is configured to observe the dripping speed of the concentrated sulfuric acid and confirm whether the dripping of the concentrated sulfuric acid has been completed through the window (31). The guide tube (4) is configured to guide the flow direction of the concentrated sulfuric acid to prevent the concentrated sulfuric acid from dripping on the container wall at the lower end.

2. The concentrated sulfuric acid adding device as claimed in claim 1, characterized in that: The needle valve (2) comprises a needle valve seat (21) and a needle valve stem (22); the first end of the needle valve seat (21) is connected to the lower end of the funnel (1); the second end of the needle valve seat (21) is connected to the upper end of the glass sight glass (3); the needle valve stem (22) is located on the side wall of the needle valve seat (21); and the needle valve (2) is configured to adjust the flow rate of the concentrated sulfuric acid flowing through the needle valve (2) by changing the size of the opening between the needle valve stem (22) and the needle valve seat (21).

3. The concentrated sulfuric acid adding device as claimed in claim 2, characterized in that, The first end of the needle valve stem (22) is needle-tip shaped, and the second end of the needle valve stem (22) is provided with a hand wheel (23), and the hand wheel (23) is configured to rotate so that the needle valve stem (22) rotates along an axis to adjust the opening size between the first end of the needle valve stem (22) and the needle valve seat (21).

4. The concentrated sulfuric acid adding device as claimed in claim 1, characterized in that: The outer side of the window (31) of the glass vision device (3) is surrounded by a plurality of reinforcing strips (32), the upper ends and lower ends of the plurality of reinforcing strips (32) are connected to the upper cover and the lower cover of the glass vision device (3), the plurality of reinforcing strips (32) are parallel to the axis of the glass vision device (3), and the reinforcing strips (32) are configured to improve the mechanical strength of the glass vision device (3) and resist external impact.

5. The concentrated sulfuric acid adding device as claimed in claim 1, characterized in that, Sealing gaskets are provided between the viewing window (31) of the glass sight glass (3) and the upper cover and the lower cover of the glass sight glass (3), and the sealing gaskets are configured to keep the glass sight glass (3) in a sealed state to prevent leakage of the concentrated sulfuric acid.

6. The concentrated sulfuric acid dropping device according to claim 1, characterized in that, The inner wall of the upper end of the flow guide tube (4) is provided with an internal thread.

7. The concentrated sulfuric acid dropping device as claimed in claim 6, characterized in that: The lower end of the glass sight glass (3) is provided with an external thread, and the external thread is matched and connected with the internal thread.

8. The concentrated sulfuric acid adding device as claimed in claim 1, characterized in that, The lower end of the flow guide pipe (4) is a flange (5), and the flange (5) is configured to be connected with the reaction kettle.

9. The concentrated sulfuric acid adding device as claimed in claim 8, characterized in that: The flange (5) is provided with a plurality of circumferentially arranged connection holes.

10. The concentrated sulfuric acid dropping device according to claim 9, characterized in that: It also includes a plurality of fastening screws, which pass through the connecting holes to connect the concentrated sulfuric acid dropping device with the reaction kettle.

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