Dialysis device for laboratory

Abstract

The dialysis device for the laboratory comprises a reaction barrel and a base, the reaction barrel is installed at the top of the base, an electric push rod is fixedly installed on the top wall of the base, the movable end of the electric push rod is fixedly connected with a top plate, and a driving mechanism for improving the dialysis effect is arranged at the bottom of the top plate; the driving mechanism comprises a rotating shaft rotationally connected to the bottom wall of the top plate, a second conical wheel is fixedly connected to the side wall of the rotating shaft, a plurality of stirring blades are uniformly distributed and fixedly connected to the side wall of the bottom end of the rotating shaft, an L-shaped plate is fixedly connected to the bottom wall of the top plate, and a round pipe is rotationally connected to the inner wall of the L-shaped plate in a penetrating mode in the vertical direction. By arranging the stirring blades, the circular tube and other structures, when the rotating shaft drives the multiple stirring blades to rotate clockwise, the third conical wheel drives the circular tube, the two concave blocks and the dialysis bag to rotate anticlockwise, so that the dialysis bag actively makes contact with flowing dialysate, and the dialysis capacity of materials to be dialyzed in the dialysis bag is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of dialysis devices, in particular to a dialysis device for laboratory use. Background Art

[0002] In the solution of biological macromolecules and their nano-assemblies containing chemical small molecules, it is usually necessary to remove the chemical small molecules, such as various salts, catalysts, reaction reagents, etc. For laboratory technicians, dialysis technology is commonly used, which is easy to operate and has low cost.

[0003] The current laboratory dialysis device has the following problems in actual operation:

[0004] 1. In the prior art, the dialysate is stirred in a certain direction (such as clockwise) by a stirring blade, and the dialysate will also move in a clockwise direction synchronously, thereby accelerating the dialysate's dialysis speed on small molecules in the dialysis bag. However, the dialysis bag will deflect or rotate under the unidirectional impact of the dialysate, resulting in poor dialysis effect;

[0005] 2. For dialysis bags of different specifications, it is necessary to replace dialysis devices of different models to better clamp and dialysis, which is a cumbersome operation.

[0006] To this end, we proposed a dialysis device for laboratory use. Utility Model Content

[0007] The utility model aims to solve the shortcomings in the prior art and provides a laboratory dialysis device.

[0008] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0009] A laboratory dialysis device comprises a reaction bucket and a base, wherein the reaction bucket is mounted on the top of the base, an electric push rod is fixedly mounted on the top wall of the base, a movable end of the electric push rod is fixedly connected to a top plate, and a driving mechanism for improving the dialysis effect is provided at the bottom of the top plate; the driving mechanism comprises a rotating shaft rotatably connected to the bottom wall of the top plate, a second conical wheel is fixedly connected to the side wall of the rotating shaft, a plurality of stirring blades are evenly fixedly connected to the side wall of the bottom end of the rotating shaft, an L-shaped plate is fixedly connected to the bottom wall of the top plate, a circular tube is rotatably connected to the inner wall of the L-shaped plate along the vertical direction, a third conical wheel is fixedly connected to the top side wall of the circular tube, the circular tube is sleeved outside the rotating shaft, a motor is fixedly connected to the side wall of the L-shaped plate, and an output end of the motor is fixedly connected to the first conical wheel; a mounting mechanism for clamping and stretching a dialysis bag is provided on the side wall of the circular tube.

[0010] Preferably, the second conical wheel and the third conical wheel are symmetrically arranged on both sides of the first conical wheel, the first conical wheel and the second conical wheel are meshed and connected, and the first conical wheel and the third conical wheel are meshed and connected.

[0011] Preferably, the mounting mechanism comprises a guide rail fixedly connected to the side wall of the circular tube, the side wall of the guide rail being provided with a plurality of limit grooves, the side wall of the guide rail being slidably connected with two concave blocks, the inner wall of each concave block being provided with a cavity, the inner wall of the cavity being symmetrically penetrated by a wedge rod slidably connected thereto, the inner wall of the cavity being penetrated by a limit block slidably connected thereto, and the side wall of the limit block being symmetrically provided with right-angle holes.

[0012] Preferably, each side wall of the wedge-shaped rod is sleeved with a tension spring, one end of the tension spring is fixedly connected to the side wall of the wedge-shaped rod, and the other end of the tension spring is fixedly connected to the inner side wall of the cavity.

[0013] Preferably, a return spring is fixedly connected to the inner wall of the limit block, and one end of the return spring away from the limit block is fixedly connected to the inner wall of the cavity.

[0014] Preferably, each of the side walls of the concave blocks is fixedly connected to a concave plate, the inner wall of the concave plate is symmetrically provided with threaded holes, and a threaded rod is threadedly connected inside each of the threaded holes.

[0015] Preferably, one end of each of the threaded rods is rotatably connected to a clamping plate, and one end of the threaded rod away from the clamping plate is fixedly connected to a handle.

[0016] Beneficial effects of the utility model:

[0017] 1. By setting structures such as threaded rods, clamping plates and concave plates, and rotating multiple handles, the threaded rods on each concave plate drive the corresponding clamping plates to clamp the dialysis bag, thereby completing the clamping and fixing of the upper and lower ends of the dialysis bag;

[0018] 2. The experimenter presses the wedge-shaped rods on both sides of one of the concave blocks, and disengages the limit block and the limit groove by setting structures such as the limit block, the right-angle hole and the reset spring, and then drags the concave block to slide along the vertical direction on the side wall of the guide rail, so that the two concave blocks gradually move away from each other, and the dialysis bag will be stretched, so that the device can be installed and stretched for dialysis bags of different sizes, which improves the applicability of the device, and can also adjust the height of the clamped dialysis bag by synchronously moving the two concave blocks, so that the dialysis bag can be located at different depths for dialysis;

[0019] 3. By setting up multiple conical wheels, stirring blades and circular tubes, when the rotating shaft drives the multiple stirring blades to rotate clockwise to stir the dialysate filled in the reaction barrel to accelerate the flow exchange of the dialysate, the third conical wheel drives the circular tube, the guide rail, the two concave blocks and the dialysis bag to rotate counterclockwise, so that the dialysis bag actively contacts the flowing dialysis fluid, thereby improving the dialysis capacity of the dialyzed material in the dialysis bag and preventing the dialysis bag from rotating and winding. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 The utility model is a schematic structural diagram of a laboratory dialysis device.

[0021] Figure 2 The utility model is a schematic diagram of the structure of the interior of a hollow cavity in a laboratory dialysis device.

[0022] Figure 3 The present invention is a schematic diagram of the positional relationship of right-angle holes in a laboratory dialysis device proposed by the present invention.

[0023] Figure 4 The utility model is a schematic diagram of the positional relationship among a circular tube, a guide rail and a concave block in a laboratory dialysis device.

[0024] Figure 5 This is an appearance diagram of a laboratory dialysis device proposed by the utility model.

[0025] In the figure: 1 reaction barrel, 2 base, 3 electric push rod, 4 top plate, 5 L-shaped plate, 6 motor, 7 first conical wheel, 8 rotating shaft, 9 second conical wheel, 10 third conical wheel, 11 round tube, 12 stirring blade, 13 guide rail, 14 concave block, 15 cavity, 16 limit groove, 17 limit block, 19 wedge rod, 20 tension spring, 21 return spring, 22 concave plate, 23 handle, 24 threaded hole, 25 threaded rod, 26 clamping plate, 27 right-angle hole. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0027] Reference Figure 1-Figure 5 A laboratory dialysis device comprises a reaction barrel 1 and a base 2. The reaction barrel 1 is mounted on the top of the base 2. The reaction barrel 1 is filled with dialysis fluid. An electric push rod 3 is fixedly mounted on the top wall of the base 2. The model of the electric push rod 3 is DTZ-100. The movable end of the electric push rod 3 is fixedly connected to a top plate 4. The bottom of the top plate 4 is provided with a driving mechanism for improving the dialysis effect.

[0028] The driving mechanism includes a rotating shaft 8 rotatably connected to the bottom wall of the top plate 4, a second conical wheel 9 is fixedly connected to the side wall of the rotating shaft 8, a plurality of stirring blades 12 are evenly fixedly connected to the side wall of the bottom end of the rotating shaft 8, an L-shaped plate 5 is fixedly connected to the bottom wall of the top plate 4, a circular tube 11 is rotatably connected to the inner wall of the L-shaped plate 5 along the vertical direction, the circular tube 11 can only rotate on the inner wall of the L-shaped plate 5 without generating vertical displacement, a third conical wheel 10 is fixedly connected to the top side wall of the circular tube 11, the circular tube 11 is sleeved on the outside of the rotating shaft 8, a motor 6 is fixedly connected to the side wall of the L-shaped plate 5, the model of the motor 6 is Y60M2-2, and the output end of the motor 6 is fixedly connected to the first conical wheel 7;

[0029] The side wall of the circular tube 11 is provided with a mounting mechanism for clamping and stretching the dialysis bag.

[0030] The second conical wheel 9 and the third conical wheel 10 are symmetrically arranged on both sides of the first conical wheel 7. The first conical wheel 7 and the second conical wheel 9 are meshed and connected. The first conical wheel 7 and the third conical wheel 10 are meshed and connected. When the output end of the motor 6 drives the first conical wheel 7 to rotate, the first conical wheel 7 will drive the second conical wheel 9 and the third conical wheel 10 to rotate. Since the second conical wheel 9 and the third conical wheel 10 are respectively arranged on both sides of the first conical wheel 7, the rotation direction of the rotating shaft 8 and the multiple stirring blades 12 is opposite to the direction in which the dialysis bag is driven by the circular tube 11 to rotate.

[0031] The mounting mechanism includes a guide rail 13 fixedly connected to the side wall of the circular tube 11, and a plurality of limit grooves 16 are provided on the side wall of the guide rail 13. Two concave blocks 14 are slidably connected to the side wall of the guide rail 13. The plurality of limit grooves 16 are equidistantly arranged on the side wall of the guide rail 13 from top to bottom, so as to facilitate the position adjustment of the concave blocks 14. A cavity 15 is provided on the inner wall of each concave block 14, and a wedge rod 19 is symmetrically penetrated and slidably connected to the inner wall of the cavity 15 in the horizontal direction. One end of the wedge rod 19 is located inside the cavity 15, and the other end of the wedge rod 19 is located outside the concave block 14. The inner wall of the cavity 15 penetrates and is slidably connected to a limit block 17. The side wall of the limit block 17 is symmetrically provided with right-angle holes 27, and the inclined surface portion of the wedge rod 19 slides against a corresponding right-angle hole 27.

[0032] A tension spring 20 is sleeved on the side wall of each wedge rod 19 , one end of the tension spring 20 is fixedly connected to the side wall of the wedge rod 19 , and the other end of the tension spring 20 is fixedly connected to the inner wall of the cavity 15 .

[0033] A return spring 21 is fixedly connected to the inner wall of the limit block 17. One end of the return spring 21 away from the limit block 17 is fixedly connected to the inner wall of the cavity 15. The return spring 21 can be reset when there is no external force on the limit block 17. The limit block 17 and the limit groove 16 are fitted together.

[0034] The side wall of each concave block 14 is fixedly connected with a concave plate 22, and the inner wall of the concave plate 22 is symmetrically provided with threaded holes 24. A threaded rod 25 is threadedly connected inside each threaded hole 24, and the threaded rod 25 can move a certain distance inside the threaded hole 24 after rotation.

[0035] One end of each threaded rod 25 is rotatably connected to a clamping plate 26 so that the threaded rod 25 does not drive the clamping plate 26 to rotate when rotating, but the threaded rod 25 can drive the clamping plate 26 to move horizontally synchronously. The end of the threaded rod 25 away from the clamping plate 26 is fixedly connected to a handle 23.

[0036] In the utility model, the electric push rod 3 is first turned on, and the movable end of the electric push rod 3 drives the top plate 4 to move a certain distance upward in the vertical direction, so that the top plate 4 drives the driving mechanism and the mounting mechanism to rise a certain distance for the convenience of the experimenter to operate. Then the experimenter places the dialysis bag in the position between the two concave plates 22, and then rotates a plurality of turning hands 23. Each turning hand 23 will drive the threaded rod 25 fixedly connected thereto to rotate. Since the end of the threaded rod 25 away from the turning hand 23 is rotatably connected to the clamping plate 26, and the threaded rod 25 is threadedly connected inside the corresponding threaded hole 24, the threaded rod 25 will drive the corresponding clamping plate 26 to move a certain distance, so that the two clamping plates 26 in each concave plate 22 are close to each other, and then the two clamping plates 26 clamp the dialysis bag together. Since the side wall of the guide rail 13 is provided with two concave blocks 14, each concave block 14 side wall is provided with a concave plate 22 and two clamping plates 26, and then the upper and lower ends of the dialysis bag can be clamped and fixed.

[0037] like Figure 2-4 As shown, the experimenter then presses the wedge-shaped rods 19 on both sides of one of the concave blocks 14, and the two wedge-shaped rods 19 slide toward each other after being squeezed. Then, the inclined surface portion of each wedge-shaped rod 19 will slide against a corresponding right-angle hole 27, thereby pushing the limit block 17 to slide a certain distance and then disengage the limit groove 16 from the stuck state. Then, the experimenter can continue to squeeze the two wedge-shaped rods 19 while dragging the concave block 14 to slide along the side wall of the guide rail 13 in the vertical direction, so that the two concave blocks 14 gradually move away from each other, and then the dialysis bag clamped between the side walls of the two concave blocks 14 will It will be stretched. After the dialysis bag is fully stretched, the experimenter releases the pulling on the dialysis bag. At this time, the limit block 17 can slide in the opposite direction for a distance under the action of the reset spring 21, and then be inserted into an adjacent limit groove 16 for limiting. By arranging structures such as the wedge rod 19, the concave plate 22 and then the splint 26, dialysis bags of different sizes can be installed and stretched, thereby improving the application range of the device. In addition, the height of the clamped dialysis bag can be adjusted by synchronously moving the two concave blocks 14, so that the dialysis bag can be located at different depths for dialysis.

[0038] Finally, the motor 6 is turned on, and the output end of the motor 6 drives the first conical wheel 7 to rotate, and the first conical wheel 7 drives the second conical wheel 9 and the third conical wheel 10 which are respectively meshed and connected thereto to rotate. Since the second conical wheel 9 is fixedly connected to the side wall of the rotating shaft 8, the multiple stirring blades 12 fixedly connected to the bottom side wall of the rotating shaft 8 will rotate synchronously, thereby stirring the dialysate filled in the reaction barrel 1 to accelerate the flow exchange of the dialysate, and the third conical wheel 10 drives the circular tube 11 to rotate, and the circular tube 11 drives the dialysis bag to rotate through structures such as the guide rail 13, two concave blocks 14 and the concave plate 22. Since the second conical wheel 9 and the third conical wheel 10 are respectively arranged on both sides of the first conical wheel 7, the rotation direction of the rotating shaft 8 and the multiple stirring blades 12 is opposite to the direction in which the circular tube 11 drives the dialysis bag to rotate, thereby improving the dialysis capacity of the material to be dialyzed in the dialysis bag, and can also avoid the situation where the dialysis bag rotates and entangles due to the dialysate stirring in one direction.

[0039] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A laboratory dialysis device, comprising a reaction bucket (1) and a base (2), wherein the reaction bucket (1) is mounted on the top of the base (2), and characterized in that: An electric push rod (3) is fixedly mounted on the top wall of the base (2); a movable end of the electric push rod (3) is fixedly connected to a top plate (4); and a driving mechanism for improving the dialysis effect is provided at the bottom of the top plate (4); The driving mechanism comprises a rotating shaft (8) rotatably connected to the bottom wall of the top plate (4); a second conical wheel (9) is fixedly connected to the side wall of the rotating shaft (8); a plurality of stirring blades (12) are evenly distributed and fixedly connected to the side wall of the bottom end of the rotating shaft (8); an L-shaped plate (5) is fixedly connected to the bottom wall of the top plate (4); a circular tube (11) is rotatably connected to the inner wall of the L-shaped plate (5) penetrating in a vertical direction; a third conical wheel (10) is fixedly connected to the top side wall of the circular tube (11); the circular tube (11) is sleeved outside the rotating shaft (8); a motor (6) is fixedly connected to the side wall of the L-shaped plate (5); and the output end of the motor (6) is fixedly connected to the first conical wheel (7); The side wall of the circular tube (11) is provided with a mounting mechanism for clamping and stretching the dialysis bag.

2. A laboratory dialysis device according to claim 1, characterized in that: The second conical wheel (9) and the third conical wheel (10) are symmetrically arranged at two sides of the first conical wheel (7); the first conical wheel (7) and the second conical wheel (9) are meshingly connected; and the first conical wheel (7) and the third conical wheel (10) are meshingly connected.

3. A laboratory dialysis device according to claim 1, characterized in that: The mounting mechanism comprises a guide rail (13) fixedly connected to the side wall of the circular tube (11), the side wall of the guide rail (13) being provided with a plurality of limit grooves (16), the side wall of the guide rail (13) being slidably connected to two concave blocks (14), the inner wall of each concave block (14) being provided with a cavity (15), the inner wall of the cavity (15) being symmetrically penetrated by a wedge-shaped rod (19) being slidably connected thereto, the inner wall of the cavity (15) being penetrated by a limit block (17) being slidably connected thereto, and the side wall of the limit block (17) being symmetrically provided with right-angle holes (27).

4. A laboratory dialysis device according to claim 3, characterized in that: The inclined surface portion of the wedge rod (19) and an adjacent right-angle hole (27) slide against each other, and a tension spring (20) is sleeved on the side wall of each wedge rod (19), one end of the tension spring (20) is fixedly connected to the side wall of the wedge rod (19), and the other end of the tension spring (20) is fixedly connected to the inner wall of the cavity (15).

5. A laboratory dialysis device according to claim 4, characterized in that: A return spring (21) is fixedly connected to the inner wall of the limit block (17), and one end of the return spring (21) away from the limit block (17) is fixedly connected to the inner wall of the cavity (15).

6. A laboratory dialysis device according to claim 5, characterized in that: The side wall of each concave block (14) is fixedly connected to a concave plate (22), the inner wall of the concave plate (22) is symmetrically provided with threaded holes (24), and the interior of each threaded hole (24) is threadedly connected to a threaded rod (25).

7. A laboratory dialysis device according to claim 6, characterized in that: One end of each threaded rod (25) is rotatably connected to a clamping plate (26), and one end of the threaded rod (25) away from the clamping plate (26) is fixedly connected to a handle (23).

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