Reaction kettle for medicine synthesis

By setting a scraper and a water spray mechanism on the stirring shaft of the reaction kettle for pharmaceutical synthesis for high-pressure water erosion and cleaning, and using a cold air ring for air cooling and heat dissipation, the shortcomings of the existing reactor in terms of cleaning and cooling are solved, and the effect of efficient cleaning and gentle heat dissipation is achieved.

CN222855445UActive Publication Date: 2025-05-13TIANJIN MEIHUA PHARM CO LTD +1
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Patent Information

Application Number
CN202421746203.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-23
Publication Date
2025-05-13
Estimated Expiration
2034-07-23

AI Technical Summary

Technical Problem

The existing reaction kettle for pharmaceutical synthesis cannot handle the dead corners inside the kettle body during cleaning, and the cooling method can easily lead to cracks in the kettle body.

Method used

A reactor for pharmaceutical synthesis was designed, and a scraper and a water spray mechanism were installed on the agitating shaft for high-pressure water erosion and cleaning to avoid blind spots; at the same time, a cold air ring, a lifting mechanism and an air inlet mechanism were used for air cooling and heat dissipation to avoid cracks caused by extreme cooling.

Benefits of technology

It realizes efficient cleaning of the inside of the kettle body, avoids the existence of dead corners, saves time and effort, and has high cleaning efficiency; at the same time, through gentle air-cooling and heat dissipation, the risk of cracking of the kettle body is avoided.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a reaction kettle for medicine synthesis, which comprises a kettle body, a bracket arranged at the bottom of the kettle body, an inner cylinder arranged inside the kettle body, a cover plate detachably arranged at the top of the inner cylinder, an interlayer arranged between the inner cylinder and the kettle body, a medium inlet / outlet communicated with the interlayer arranged on the kettle body, and a ring-shaped cold air ring sleeved on the outer side of the kettle body, a plurality of blowing ports facing the kettle body are formed in the inner side of the cold air ring, a lifting mechanism for driving the cold air ring to lift and an air inlet mechanism connected with the cold air ring are arranged on the bracket, a stirring shaft extending into the inner cylinder is rotationally connected to the top of the cover plate, a plurality of pairs of stirring blades are arranged on the stirring shaft, and a first motor for driving the stirring shaft to rotate is arranged at the top of the cover plate; a scraping plate in contact with the inner wall of the inner cylinder is arranged on the stirring shaft, and a water spraying mechanism is arranged on the scraping plate. The utility model is convenient to clean and cool, and is convenient to use.
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Description

Technical Field

[0001] The utility model relates to the field of reaction kettles, in particular to a reaction kettle for drug synthesis. Background Art

[0002] A reactor is broadly understood as a container for physical or chemical reactions. Through the structural design and parameter configuration of the container, the heating, evaporation, cooling and low-speed mixing functions required by the process are achieved. Reactors are widely used in the fields of petroleum, chemical industry, rubber, pesticides, dyes, medicines and food.

[0003] Commonly used reactors for drug synthesis, such as publication number: CN212068752U (a synthesis reactor for health care drug manufacturing), have the following deficiencies:

[0004] 1. The reactor must be cleaned internally after each operation, but there are dead corners inside the reactor, and the existing cleaning device cannot clean the dead corners.

[0005] 2. The existing reactor needs to be cooled after the synthesis reaction is completed. The method of cooling by surrounding with a water cooling pipe is easy to cause cracks in the reactor body. Summary of the invention

[0006] The utility model aims to solve the deficiencies of the prior art and provides a reaction kettle for drug synthesis.

[0007] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a reaction kettle for drug synthesis, comprising a kettle body, a bracket is provided at the bottom of the kettle body, an inner cylinder is provided inside the kettle body, a cover plate is detachably installed on the top of the inner cylinder, an interlayer is provided between the inner cylinder and the kettle body, a medium inlet and outlet connected with the interlayer is provided on the kettle body, a circular cold air ring is sleeved on the outer side of the kettle body, a plurality of air blowing ports facing the kettle body are provided on the inner side of the cold air ring, a lifting mechanism for driving the cold air ring to rise and fall, and an air inlet mechanism connected with the cold air ring are provided on the bracket, a stirring shaft extending into the inner cylinder is rotatably connected to the top of the cover plate, a plurality of pairs of stirring blades are provided on the stirring shaft, a first motor for driving the stirring shaft to rotate is provided on the top of the cover plate, a scraper contacting the inner wall of the inner cylinder is provided on the stirring shaft, and a water spraying mechanism is provided on the scraper.

[0008] Particularly, the inner cylinder and the cover plate are connected via flanges.

[0009] In particular, the lifting mechanism includes a second motor, which is installed on one side of the top of the bracket, and a plurality of fixed plates are evenly distributed on the circumference of the top outer side of the kettle body. A lead screw is fixedly connected to the main shaft of the second motor, and the top of the lead screw is rotatably connected to the corresponding fixed plate. A guide rod is fixedly connected between the remaining fixed plates and the bracket, and a plurality of movable plates corresponding to the fixed plates are evenly distributed on the circumference of the outer side of the cold air ring, and the guide rod passes through the corresponding movable plates, and the lead screw is threadedly connected to the corresponding movable plate.

[0010] Particularly, the air inlet mechanism comprises an air cooler, which is mounted on one side of the top of the bracket, and a bellows expansion pipe is connected to the air outlet of the air cooler, which is connected to the cold air ring.

[0011] Particularly, a mounting frame is provided on the top of the cover plate, the top of the stirring shaft passes through the mounting frame, the first motor is installed on the mounting frame and is transmitted to the stirring shaft through gears.

[0012] In particular, the water spraying mechanism includes a water spraying pipe installed on the front side of the scraper, a plurality of nozzles are provided on the side of the water spraying pipe facing the inner wall of the inner cylinder, a cavity connected to the water spraying pipe is provided on the top of the stirring shaft, a connecting head is installed on the top of the cavity, a water inlet pipe is connected to the mounting frame, and the outlet end of the water inlet pipe is rotatably connected to the connecting head.

[0013] The beneficial effects of the utility model are as follows: the utility model arranges a scraper on the stirring shaft, and arranges a water spraying mechanism on the scraper, so that during cleaning, high-pressure water flushes the inner wall of the inner cylinder, and at the same time the scraper scrapes the inner wall of the inner cylinder, the cleaning effect is good, the inner wall of the inner cylinder can be completely scraped in place by the scraper, and the existence of cleaning dead corners is avoided, cleaning is time-saving and labor-saving, and the cleaning efficiency is high; by arranging a cold air ring, a lifting mechanism, and an air inlet mechanism, air cooling is performed on the outside of the kettle body to dissipate heat from the kettle body, the cooling method is relatively gentle, and rapid cooling to avoid cracking of the kettle body. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the structure of the utility model;

[0015] Figure 2 It is a schematic diagram of the positions of the guide rod, the movable plate and the lead screw on the cold air ring of the utility model;

[0016] In the figure: 1- kettle body; 2- bracket; 3- inner cylinder; 4- cover plate; 5- interlayer; 6- cold air ring; 7- stirring shaft; 8- stirring blade; 9- first motor; 10- scraper; 11- second motor; 12- lead screw; 13- fixed plate; 14- movable plate; 15- guide rod; 16- blowing port; 17- cold air blower; 18- corrugated telescopic pipe; 19- mounting frame; 20- water spray pipe; 21- nozzle; 22- cavity; 23- water inlet pipe;

[0017] The following is a detailed description of the embodiments of the present invention with reference to the accompanying drawings. DETAILED DESCRIPTION

[0018] The utility model is further described below in conjunction with the accompanying drawings and embodiments:

[0019] like Figure 1-Figure 2As shown, a reaction kettle for drug synthesis comprises a kettle body 1, a bracket 2 is provided at the bottom of the kettle body 1, an inner cylinder 3 is provided inside the kettle body 1, a cover plate 4 is detachably installed on the top of the inner cylinder 3, a feeding port is provided on the cover plate 4, a discharge port passing through the kettle body 1 is provided at the bottom of the inner cylinder 3, the inner cylinder 3 and the cover plate 4 are connected by a flange, an interlayer 5 is provided between the inner cylinder 3 and the kettle body 1, a medium inlet and outlet connected to the interlayer 5 is provided on the kettle body 1, and when the reaction needs to be heated, a heat-conducting medium such as heat-conducting oil is selected as the medium.

[0020] A circular cold air ring 6 is sleeved on the outer side of the kettle body 1, and a plurality of blowing ports 16 facing the kettle body 1 are arranged on the inner side of the cold air ring 6, and a lifting mechanism for driving the cold air ring 6 to rise and fall, and an air inlet mechanism connected to the cold air ring 6 are arranged on the bracket 2, and the lifting mechanism includes a second motor 11, and the second motor 11 is installed on one side of the top of the bracket 2, and a plurality of fixed plates 13 are evenly distributed on the circumference of the outer top of the kettle body 1, and a lead screw 12 is fixedly connected to the main shaft of the second motor 11, and the top of the lead screw 12 is rotatably connected to the corresponding fixed plate 13, and a guide rod 15 is fixedly connected between the remaining fixed plates 13 and the bracket 2, and a plurality of movable plates 14 corresponding to the fixed plates 13 are evenly distributed on the outer side of the cold air ring 6 The guide rod 15 penetrates the corresponding movable plate 14, and the lead screw 12 is threadedly connected to the corresponding movable plate 14; the air inlet mechanism includes a cold air fan 17, and the cold air fan 17 is installed on one side of the top of the bracket 2, and a bellows telescopic pipe 18 is connected to the air outlet of the cold air fan 17, and the bellows telescopic pipe 18 is connected to the cold air ring 6.

[0021] The top of the cover plate 4 is rotatably connected to a stirring shaft 7 extending into the inner tube 3, and a plurality of pairs of stirring blades 8 are provided on the stirring shaft 7. A first motor 9 for driving the stirring shaft 7 to rotate is provided on the top of the cover plate 4. A mounting frame 19 is provided on the top of the cover plate 4, and the top of the stirring shaft 7 passes through the mounting frame 19. The first motor 9 is mounted on the mounting frame 19 and is transmitted to the stirring shaft 7 through gears.

[0022] A scraper 10 in contact with the inner wall of the inner cylinder 3 is provided on the stirring shaft 7, and a water spraying mechanism is provided on the scraper 10. The water spraying mechanism includes a water spraying pipe 20 installed on the front side of the scraper 10, and a plurality of nozzles 21 are provided on the side of the water spraying pipe 20 facing the inner wall of the inner cylinder 3. A cavity 22 connected to the water spraying pipe 20 is provided at the top of the stirring shaft 7, and a connector is installed at the top of the cavity 22. A water inlet pipe 23 is connected to the mounting frame 19, and the outlet end of the water inlet pipe 23 is rotatably connected to the connector.

[0023] When the utility model is working, after the material is added into the inner cylinder 3, the first motor 9 is started, and the stirring shaft 7 drives the stirring blade 8 to rotate to mix the materials. If heating is required, the heat-conducting medium is circulated into the interlayer 5 through the medium inlet and outlet, and discharged through the discharge port after the reaction is completed. After the reaction is completed, the kettle body 1 needs to be cooled. At this time, the second motor 11 and the air cooler 17 are started, and the cold air ring 6 rises and falls along the kettle body 1 and blows cold air toward the kettle body 1 to dissipate heat. When cleaning the inner cylinder 3, the first motor 9 is started, and the scraper 10 scrapes off the material attached to the inner wall of the inner cylinder 3. At the same time, the water inlet pipe 23 fills water into the water spray pipe 20, and the nozzle 21 sprays high-pressure water toward the inner wall of the inner cylinder 3 to flush away the attached material. After the cleaning is completed, the waste water can be discharged through the discharge port.

[0024] The utility model arranges a scraper 10 on the stirring shaft 7, and arranges a water spraying mechanism on the scraper 10, so that during cleaning, high-pressure water flushes the inner wall of the inner cylinder 3, and at the same time the scraper 10 scrapes the inner wall of the inner cylinder 3, the cleaning effect is good, the inner wall of the inner cylinder 3 can be completely scraped in place by the scraper 10, and the existence of cleaning dead corners is avoided, the cleaning is time-saving and labor-saving, and the cleaning efficiency is high; by arranging a cold air ring 6, a lifting mechanism, and an air inlet mechanism, air cooling is performed on the outside of the kettle body 1 to dissipate heat from the kettle body 1, the cooling method is relatively gentle, and rapid cooling to avoid cracking of the kettle body 1.

[0025] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0026] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present utility model, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0027] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] The utility model is described above by way of example in conjunction with the accompanying drawings. It is obvious that the specific implementation of the utility model is not limited to the above-mentioned method. As long as various improvements are made using the method concept and technical solution of the utility model, or are directly applied to other occasions without improvement, they are all within the protection scope of the utility model.

Claims

1. A reaction kettle for drug synthesis, comprising a kettle body (1), a support (2) being provided at the bottom of the kettle body (1), characterized in that: An inner cylinder (3) is provided inside the kettle body (1), a cover plate (4) is detachably mounted on the top of the inner cylinder (3), an interlayer (5) is provided between the inner cylinder (3) and the kettle body (1), a medium inlet and outlet connected to the interlayer (5) is provided on the kettle body (1), a circular cold air ring (6) is sleeved on the outer side of the kettle body (1), a plurality of air blowing ports (16) facing the kettle body (1) are provided on the inner side of the cold air ring (6), a lifting mechanism for driving the cold air ring (6) to rise and fall, and an air inlet mechanism connected to the cold air ring (6) are provided on the bracket (2), a stirring shaft (7) extending into the inner cylinder (3) is rotatably connected to the top of the cover plate (4), a plurality of pairs of stirring blades (8) are provided on the stirring shaft (7), a first motor (9) for driving the stirring shaft (7) to rotate is provided on the top of the cover plate (4), a scraper (10) in contact with the inner wall of the inner cylinder (3) is provided on the stirring shaft (7), and a water spraying mechanism is provided on the scraper (10).

2. A drug synthesis reactor according to claim 1, characterized in that: The inner cylinder (3) and the cover plate (4) are connected via a flange.

3. A drug synthesis reactor according to claim 1, characterized in that: The lifting mechanism comprises a second motor (11), which is mounted on one side of the top of the bracket (2); a plurality of fixed plates (13) are evenly distributed on the outer top of the kettle body (1); a lead screw (12) is fixedly connected to the main shaft of the second motor (11); and the top of the lead screw (12) is rotatably connected to the corresponding fixed plate (13); a guide rod (15) is fixedly connected between the remaining fixed plates (13) and the bracket (2); a plurality of movable plates (14) corresponding to the fixed plates (13) are evenly distributed on the outer circumference of the cold air ring (6); the guide rod (15) passes through the corresponding movable plates (14); and the lead screw (12) is threadedly connected to the corresponding movable plates (14).

4. A drug synthesis reactor according to claim 1, characterized in that: The air inlet mechanism comprises a cold air machine (17), which is installed on one side of the top of the bracket (2), and a corrugated telescopic tube (18) is connected to the air outlet of the cold air machine (17), and the corrugated telescopic tube (18) is connected to the cold air ring (6).

5. A drug synthesis reactor according to claim 1, characterized in that: A mounting frame (19) is provided on the top of the cover plate (4), the top of the stirring shaft (7) passes through the mounting frame (19), and the first motor (9) is mounted on the mounting frame (19) and is driven by gears with the stirring shaft (7).

6. A drug synthesis reactor according to claim 1, characterized in that: The water spraying mechanism comprises a water spraying pipe (20) mounted on the front side of the scraper (10), a plurality of nozzles (21) being arranged on the side of the water spraying pipe (20) facing the inner wall of the inner cylinder (3), a cavity (22) being arranged on the top of the stirring shaft (7) and communicating with the water spraying pipe (20), a connector being mounted on the top of the cavity (22), a water inlet pipe (23) being connected to the mounting frame (19), and an outlet end of the water inlet pipe (23) being rotatably connected to the connector.

Citation Information

Patent Citations

  • Synthetic reaction kettle for manufacturing health-care medicines

    CN212068752U