Long-acting stability detection and observation device for urokinase

By designing a long-acting stability detection and observation device for urokinase and using a transmission mechanism to drive the stirring rod to rotate, the problem of inability to observe the reaction process and uneven stirring in the prior art is solved, real-time observation of the reaction and improvement of stirring efficiency are achieved.

CN222877954UActive Publication Date: 2025-05-16NANJING NANDA PHARMA
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Patent Information

Application Number
CN202420632484.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-29
Publication Date
2025-05-16
Estimated Expiration
2034-03-29

AI Technical Summary

Technical Problem

The existing urokinase detection device cannot observe the reaction process in real time, and the stirring is uneven, resulting in slow reaction and insufficient changes in urokinase.

Method used

A long-acting stability detection and observation device for urokinase is designed, including a base, rotating shaft, turntable, glass beaker, stirring mechanism and driving mechanism. The stirring rod is driven to rotate through the transmission mechanism to improve the stirring efficiency, and the design of adjustable support blocks and glass beakers is convenient to observe the reaction process.

Benefits of technology

Real-time observation of urokinase reaction is achieved, the uniformity and efficiency of stirring is improved, the changes in urokinase are promoted, and the problem of slow reaction is solved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a urokinase long-acting stability detection and observation device, which relates to the technical field of urokinase detection, and comprises a base, the upper surface of the base is rotatably connected with a rotating shaft, the upper end of the rotating shaft is fixedly connected with a turntable, the upper surface of the turntable is provided with a glass beaker, the upper surface of the base is fixedly connected with a fixed block, and the fixed block is fixedly connected with the rotating shaft. A sliding groove is formed in one side of the fixing block 14, an adjusting mechanism is arranged in the sliding groove, a supporting block is arranged on one side of the adjusting mechanism, a stirring mechanism is arranged between the supporting block and the glass beaker, and a driving mechanism is arranged between the supporting block and the rotating disc. Through the driving mechanism arranged above the supporting block, the motor is started to enable the second rotating rod to rotate, then the first gear rotates along with the second rotating rod, the first gear drives the outer gear ring to rotate, and then the rotating disc and the glass beaker can rotate, so that the stirring efficiency can be improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of urokinase detection, in particular to a urokinase long-term stability detection and observation device. Background Art

[0002] Urokinase is a proteolytic enzyme that activates plasminogen to convert it into plasmin and then produces fibrinolysis. It is an effective antithrombotic drug and is widely used in clinical practice. However, in the production process of urokinase, it is usually necessary to conduct multiple tests on it.

[0003] Among them, a urokinase purity detection device with publication number CN218035997U is disclosed; it includes: a box body, a purity detector is arranged on the surface of the box body, a motor is arranged on the surface of the box body, a rotating shaft is arranged on the transmission end of the motor, a stirring blade is arranged on the surface of the rotating shaft, a groove is provided on the surface of the stirring blade arranged at the bottom of the rotating shaft, a scraper is arranged in the groove, a through hole is provided on the surface of the stirring blade, a pull rod is inserted in the through hole, and a spring is provided on the surface of the pull rod.

[0004] The above solution has the following shortcomings:

[0005] In the above technical solution, the progress of the reaction cannot be observed in real time when urokinase is detected, and the urokinase is not stirred evenly enough, which makes the reaction slow and causes the urokinase to change inconspicuously. Utility Model Content

[0006] In view of the above problems existing in the existing urokinase purity detection device, the present utility model is proposed.

[0007] Therefore, the purpose of the utility model is to provide a urokinase long-term stability detection and observation device, which solves the problem that the reaction progress cannot be observed in real time when detecting urokinase, and the urokinase is not stirred evenly enough, resulting in a slow reaction and unclear changes in urokinase.

[0008] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0009] A urokinase long-term stability detection and observation device comprises a base, the upper surface of the base is rotatably connected to a rotating shaft, the upper end of the rotating shaft is fixedly connected to a turntable, a glass beaker is placed on the upper surface of the turntable, a fixed block is fixedly connected to the upper surface of the base, a slide groove is provided on one side of the fixed block 14, an adjustment mechanism is provided inside the slide groove, a support block is provided on one side of the adjustment mechanism, a stirring mechanism is provided between the support block and the glass beaker, a driving mechanism is provided between the support block and the turntable, the turntable is rotated by the driving mechanism, a cavity is provided inside the support block, a transmission mechanism is provided inside the cavity, and the driving mechanism drives the stirring mechanism through the transmission mechanism.

[0010] Preferably, the adjustment mechanism includes a screw rod, a knob and a slider, the screw rod is rotatably connected to the inside of the slide slot, the slider is threadedly sleeved on the rod wall of the screw rod, and the upper end of the screw rod passes through the upper end of the slide slot and is fixedly connected to the knob.

[0011] Preferably, the stirring mechanism includes a first rotating rod and a plurality of stirring rods, a through hole is opened at one end of the lower surface of the cavity, the first rotating rod is rotatably connected to the inside of the through hole, and each stirring rod is symmetrically fixedly connected to the rod wall of the first rotating rod.

[0012] Preferably, the driving mechanism includes a second rotating rod, a motor, a first gear and an outer gear ring, the second rotating rod is rotatably connected to the lower surface of the support block, the motor is fixedly connected to the upper surface of the support block, the upper end of the second rotating rod sequentially passes through the upper and lower surfaces of the cavity and is fixedly connected to the output end of the motor, the first gear is fixedly sleeved on the rod wall at one end of the second rotating rod, and the outer gear ring is fixedly sleeved on the outer surface of the turntable and meshes with the first gear.

[0013] Preferably, the transmission mechanism includes a plurality of second gears and a third rotating rod, the third rotating rod is rotatably connected to the inside of the cavity, each of the second gears is respectively fixedly sleeved on the rod walls of the first rotating rod, the second rotating rod and the third rotating rod, and each of the second gears is meshed with each other.

[0014] Preferably, an annular baffle is fixedly connected to the upper surface of the turntable, and the annular baffle matches the glass beaker.

[0015] In the above technical solution, the technical effects and advantages provided by the utility model are:

[0016] 1. The utility model starts the motor through the driving mechanism arranged above the supporting block, so that the second rotating rod rotates, and then the first gear rotates accordingly, and then the first gear drives the outer gear ring to rotate, and then the turntable and the glass beaker can rotate, so as to increase the stirring efficiency.

[0017] 2. The utility model has a transmission mechanism disposed inside the cavity. When the motor is started, one of the second gears rotates, and then the first rotating rod is rotated through the transmission of the other two second gears, and then each stirring rod is driven to rotate and stir the urokinase. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present utility model. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0019] Figure 1 It is a schematic diagram of the structure of the utility model;

[0020] Figure 2 For the utility model Figure 1 A cross-sectional view of

[0021] Figure 3 For the utility model Figure 2 An enlarged schematic diagram of part A.

[0022] Description of reference numerals:

[0023] 1. Base; 2. Rotating shaft; 3. Turntable; 4. Fixed block; 5. Support block; 6. Screw rod; 7. Knob; 8. Slider; 9. First rotating rod; 10. Stirring rod; 11. Second rotating rod; 12. Motor; 13. First gear; 14. Outer gear ring; 15. Second gear; 16. Third rotating rod; 17. Annular baffle; 18. Glass beaker. DETAILED DESCRIPTION

[0024] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0025] The utility model embodiment discloses a device for detecting and observing the long-term stability of urokinase.

[0026] The utility model provides Figure 1-3 A device for detecting and observing the long-acting stability of urokinase is shown.

[0027] Embodiment 1

[0028] Reference Figure 1-3 A urokinase long-term stability detection and observation device comprises a base 1, the upper surface of the base 1 is rotatably connected with a rotating shaft 2, the upper end of the rotating shaft 2 is fixedly connected with a turntable 3, a glass beaker 18 is placed on the upper surface of the turntable 3, the upper surface of the base 1 is fixedly connected with a fixing block 4, a slide groove is provided on one side of the fixing block 14, an adjusting mechanism is provided inside the slide groove, a supporting block 5 is provided on one side of the adjusting mechanism, the adjusting mechanism comprises a screw rod 6, a knob 7 and a slider 8, the screw rod 6 is rotatably connected to the inside of the slide groove, the slider 8 is threadedly sleeved on the rod wall of the screw rod 6, and the upper end of the screw rod 6 passes through the upper end of the slide groove and is fixedly connected to the knob 7.

[0029] Rotate the knob 7 to rotate the screw rod 6, and then move the slider 8 up and down and drive the support block 5 to move up and down, so as to facilitate the placement of the glass beaker 18. At the same time, the progress of the reaction can be clearly observed by using the glass beaker 18.

[0030] Reference Figure 1-2A driving mechanism is provided between the support block 5 and the turntable 3, and the turntable 3 is rotated by the driving mechanism. The driving mechanism includes a second rotating rod 11, a motor 12, a first gear 13 and an outer gear ring 14. The second rotating rod 11 is rotatably connected to the lower surface of the support block 5, and the motor 12 is fixedly connected to the upper surface of the support block 5. The upper end of the second rotating rod 11 passes through the upper and lower surfaces of the cavity in sequence and is fixedly connected to the output end of the motor 12. The first gear 13 is fixedly sleeved on the rod wall at one end of the second rotating rod 11, and the outer gear ring 14 is fixedly sleeved on the outer surface of the turntable 3 and meshes with the first gear 13.

[0031] The motor 12 is started to rotate the second rotating rod 11, and then the first gear 13 rotates accordingly, and then the first gear 13 drives the outer gear ring 14 to rotate, and then the turntable 3 and the glass beaker 18 can rotate.

[0032] Reference Figure 1-3 A stirring mechanism is arranged between the support block 5 and the glass beaker 18, and the stirring mechanism includes a first rotating rod 9 and a plurality of stirring rods 10. A through hole is opened at one end of the lower surface inside the cavity, and the first rotating rod 9 is rotatably connected to the inside of the through hole. Each stirring rod 10 is symmetrically fixedly connected to the rod wall of the first rotating rod 9. A cavity is opened inside the support block 5, and a transmission mechanism is arranged inside the cavity. The driving mechanism drives the stirring mechanism through the transmission mechanism. The transmission mechanism includes a plurality of second gears 15 and a third rotating rod 16. The third rotating rod 16 is rotatably connected to the inside of the cavity. Each second gear 15 is fixedly sleeved on the rod walls of the first rotating rod 9, the second rotating rod 11 and the third rotating rod 16, respectively, and each second gear 15 is meshed with each other.

[0033] When the motor 12 is started, one of the second gears 15 rotates, and then the first rotating rod 9 can be rotated through the transmission of the other two second gears 15, and then each stirring rod 10 can be driven to rotate and stir the urokinase, and the rotation direction of each stirring rod 10 is opposite to the rotation direction of the beaker, so the stirring efficiency can be improved.

[0034] Embodiment 2

[0035] Based on Example 1, refer to Figure 1-2 An annular baffle 17 is fixedly connected to the upper surface of the turntable 3 , and the annular baffle 17 matches the glass beaker 18 .

[0036] The annular baffle 17 can prevent the beaker from falling off the turntable 3.

[0037] The above only describes some exemplary embodiments of the present invention by way of illustration. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A urokinase long-term stability detection and observation device, comprising a base (1), characterized in that: The upper surface of the base (1) is rotatably connected to a rotating shaft (2), the upper end of the rotating shaft (2) is fixedly connected to a rotating disk (3), a glass beaker (18) is placed on the upper surface of the rotating disk (3), the upper surface of the base (1) is fixedly connected to a fixing block (4), a sliding groove is provided on one side of the fixing block (4), an adjusting mechanism is provided inside the sliding groove, a supporting block (5) is provided on one side of the adjusting mechanism, a stirring mechanism is provided between the supporting block (5) and the glass beaker (18), a driving mechanism is provided between the supporting block (5) and the rotating disk (3), the rotating disk (3) is rotated by the driving mechanism, a cavity is provided inside the supporting block (5), a transmission mechanism is provided inside the cavity, and the driving mechanism drives the stirring mechanism through the transmission mechanism.

2. The urokinase long-term stability detection and observation device according to claim 1, characterized in that: The adjusting mechanism comprises a screw rod (6), a knob (7) and a slider (8); the screw rod (6) is rotatably connected to the inside of the slide groove; the slider (8) is threadedly sleeved on the rod wall of the screw rod (6); the upper end of the screw rod (6) passes through the upper end of the slide groove and is fixedly connected to the knob (7).

3. The urokinase long-term stability detection and observation device according to claim 1, characterized in that: The stirring mechanism comprises a first rotating rod (9) and a plurality of stirring rods (10); a through hole is provided at one end of the lower surface of the cavity; the first rotating rod (9) is rotatably connected to the inside of the through hole; and each stirring rod (10) is symmetrically fixedly connected to the rod wall of the first rotating rod (9).

4. The urokinase long-term stability detection and observation device according to claim 1, characterized in that: The driving mechanism comprises a second rotating rod (11), a motor (12), a first gear (13) and an outer gear ring (14); the second rotating rod (11) is rotatably connected to the lower surface of the support block (5); the motor (12) is fixedly connected to the upper surface of the support block (5); the upper end of the second rotating rod (11) passes through the upper and lower surfaces of the cavity in sequence and is fixedly connected to the output end of the motor (12); the first gear (13) is fixedly sleeved on the rod wall at one end of the second rotating rod (11); and the outer gear ring (14) is fixedly sleeved on the outer surface of the turntable (3) and meshes with the first gear (13).

5. The urokinase long-term stability detection and observation device according to claim 1, characterized in that: The transmission mechanism comprises a plurality of second gears (15) and a third rotating rod (16); the third rotating rod (16) is rotatably connected to the interior of the cavity; each of the second gears (15) is respectively fixedly sleeved on the rod walls of the first rotating rod (9), the second rotating rod (11) and the third rotating rod (16); and each of the second gears (15) is meshed with each other.

6. The urokinase long-term stability detection and observation device according to claim 1, characterized in that: An annular baffle (17) is fixedly connected to the upper surface of the turntable (3), and the annular baffle (17) matches the glass beaker (18).

Citation Information

Patent Citations

  • Prourokinase purity detection device

    CN218035997U