Cell chromatography device

By designing a cell chromatography device including box assembly, sliding assembly, telescopic assembly, control assembly and clamping assembly, the problems of unstable fixation of reagent tubes and poor ambient temperature control in the prior art are solved, and the stability and reliability of the experiment are achieved.

CN222877959UActive Publication Date: 2025-05-16CURIOX BIOSYSTEMS CHINA CO LTD
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Patent Information

Application Number
CN202420981999.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-08
Publication Date
2025-05-16
Estimated Expiration
2034-05-08

AI Technical Summary

Technical Problem

Existing cell chromatography devices cannot stably fix reagent tubes of different sizes, and cannot guarantee the constant ambient temperature during cell chromatography, resulting in abnormal experiments.

Method used

A cell chromatography device including a box assembly, a sliding assembly, a telescopic assembly, a control assembly and a clamping assembly is designed. The box assembly is equipped with a sliding assembly and a telescopic assembly, which can fix reagent tubes of any size, and achieve stable clamping of reagent tubes through the control assembly and clamping assembly. At the same time, the design of the box assembly allows temperature control of the internal environment.

Benefits of technology

The stable fixation of reagent tubes of different sizes and constant control of ambient temperature are achieved, ensuring the stability and reliability of cell chromatography experiments.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a cell chromatography device, and relates to the technical field of test devices. A reagent bottle is borne on the box body assembly, a sliding assembly is installed on the back face in the box body assembly in a sliding mode, a telescopic assembly is installed at the front end of the sliding assembly, a control assembly is fixed to the front end of the telescopic assembly, the box body assembly is directly arranged, and all the structures are installed in the box body assembly. According to the device, the box body assembly is arranged, the stable temperature can be kept through the box body assembly in the experiment process, and therefore experiment data are stabilized, the sliding assembly is slidably installed on the inner face of the box body assembly, and the telescopic assembly is arranged at the front end of the sliding assembly, so that the device can fix reagent tubes of any size and position for use; the clamping device has the effect of assisting in better clamping a reagent tube, and the problems that the clamping position of a test tube used by a cell layer cannot be adjusted, the stability during cell chromatography cannot be guaranteed, and cell chromatography is abnormal are solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of test devices, in particular to a cell chromatography device. Background Art

[0002] With the continuous development of science and technology, in order to obtain stable data and a stable experimental environment in some scientific and experimental experiments, various technical means need to be used for processing. Cell chromatography is also a processing method. Chromatography technology is a technology that separates and purifies substances based on the different migration speeds of different substances in different media due to their different physical, chemical or biological properties. Column chromatography is one of the most commonly used separation methods in the chromatography process.

[0003] When performing cell chromatography, the reagent tube needs to be fixed, but due to the different sizes and structures of the test tubes, a simple test tube clamping device cannot stably fix them. In some special cases, cell chromatography needs to maintain a certain ambient temperature, but most of the existing ones are directly at the outside end, which cannot ensure the stability and constancy of the cell chromatography, resulting in abnormal cell chromatography. Utility Model Content

[0004] The disclosed embodiment relates to a cell chromatography device, which directly sets up a box assembly and installs all structures in the box assembly, so that the temperature of the experiment process can be maintained stable through the box assembly, thereby stabilizing the experimental data. A sliding assembly is slidably installed on the inner surface of the box assembly, and a telescopic assembly is provided at the front end of the sliding assembly, so that the device can fix reagent tubes of any size and position for use, and components such as control components and clamping components have the function of assisting in better clamping the reagent tubes.

[0005] In a first aspect of the present disclosure, a cell chromatography device is provided, specifically comprising: a box assembly; a reagent bottle is carried on the box assembly, a sliding assembly is slidably installed on the inner back side of the box assembly, a telescopic assembly is installed at the front end position of the sliding assembly, a control assembly is fixed at the front end position of the telescopic assembly, a clamping assembly is hingedly installed on the control assembly, a guide assembly is installed at a position between the root of the clamping assembly and the control assembly, a reagent tube is clamped and fixed at the position of the clamping assembly, and the bottom of the reagent tube directly extends into the reagent bottle.

[0006] In at least some embodiments, the carrying box of the box assembly is configured as a vertical frame structure, and protective covers are hingedly installed at both ends of the carrying box. An observation surface is provided on the protective cover. The carrying box is directly configured as the main structure for carrying reagent tubes and reagent bottles, and an auxiliary light of a vertical structure is provided on the inner back side of the carrying box.

[0007] In at least some embodiments, the sliding bars of the sliding assembly are arranged at the box assembly, and the sliding bars are arranged as three groups of vertical structures. Sliding blocks are slidably mounted on the sliding bars, and the sliding blocks are arranged as rectangular block structures.

[0008] In at least some embodiments, the telescopic rod of the telescopic assembly is arranged at the front end of the sliding assembly, the telescopic rod is set to a horizontal structure, an external frame is slidably mounted on the telescopic rod, and a positioning pin is installed at the end of the telescopic rod.

[0009] In at least some embodiments, the support frame of the control component is configured as a rectangular frame structure, two groups of synchronous wheels are rotatably installed in the support frame, a sliding frame is slidably installed at the position of the synchronous wheels of the support frame, the sliding frames are configured as two groups symmetrical around the center of a circle, each group of sliding frames is meshed with the synchronous wheels, an external plate is provided at the outer end position of the sliding frame, and an anti-slip strip is provided on the outer end surface of the external plate.

[0010] In at least some embodiments, the clamping frames of the clamping assembly are hingedly mounted at the inner end of the external plate, a clamping wheel is rotatably mounted at the end of each set of clamping frames, and a tension spring is installed between the upper and lower clamping frames.

[0011] In at least some embodiments, the guide rods of the guide assembly are arranged at both ends of the carrier frame, the guide rods extend toward the outer ends, and the root of the clamping frame on the control assembly is arranged near the guide rods as a transmission wheel, which is directly engaged with the guide rods.

[0012] The utility model provides a cell chromatography device, which has the following beneficial effects:

[0013] In the utility model, components such as the sliding component are arranged to be slidably installed in the box component, so that the box component can cover all components, so that the box component can not only protect the test devices such as the reagent tube, but also keep the reagent tube warm, so that the test environment can be stably maintained, and the sliding component can slide in the box component, and at the same time, the telescopic component of the sliding component can be telescoped back and forth, so that the clamping component on the telescopic component can stably clamp the reagent tube of any size for use, and the control component on the telescopic component has the function of assisting the clamping component to be synchronously unfolded, and the control component can be manually controlled from one side, and the guide components at the positions of the clamping components are arranged as a gear rack structure, so that when the control component is controlled, the clamping component follows the swing of the guide component close to the control component, so that the clamping component can better take and put the reagent tube.

[0014] In addition, in order to ensure the temperature and environment of the reagent tubes during the experiment, protective covers are directly installed on both ends of the carrying box, so that the protective covers can protect the reagent tubes and reagent bottles, while ensuring the stability of the box assembly as a whole. The observation surface of the protective cover can better observe the interior of the box assembly, and an auxiliary light is set on the back panel of the carrying box so that the auxiliary light can directly illuminate the reagent tubes on the box assembly, making it convenient to observe the usage of the reagent tubes and increasing the effect of the experiment.

[0015] In addition, the sliding bar is directly set on the box assembly, so that the negative sliding block can be stably slid and installed on the sliding bar, thereby achieving a stable sliding control effect on the sliding block on the sliding bar, allowing the sliding assembly to better slide to achieve a corresponding effect on the length of the reagent tube, and the front end position of the sliding assembly is slidably installed on the external frame, so that the entire telescopic assembly can be arbitrarily slid and adjusted, and the front end of the telescopic assembly can be conveniently and directly adjusted to a specified position, and the inner end of the positioning pin at the end position of the telescopic rod is directly in contact with the external frame, so that the positioning pin has the function of controlling the telescopic position of the external frame.

[0016] In addition, when the control component is in use as a whole, the external plate on one side can be directly pressed to allow the external plate to drive the sliding frame to slide, so that the two sets of sliding frames with symmetrical centers of the circle can move synchronously through two sets of synchronous wheels, thereby achieving the external plate being controlled from one side while allowing the external plates at both ends to move synchronously, which facilitates direct control of the control component, and the anti-slip groove at the outer end of the external plate has a corresponding anti-slip effect when in contact.

[0017] In addition, the tension spring is connected between the upper and lower clamping frames, so that the clamping frame can be swung stably toward the inner end through the tension spring, so that the clamping wheel of the clamping frame can be directly clamped on the reagent tube, thereby achieving the clamping effect of the clamping assembly on the reagent tube. The clamping wheel at the end position of the clamping frame is convenient for the clamping wheel to directly contact the reagent tube, thereby achieving the stable contact effect between the clamping assembly and the reagent tube.

[0018] In addition, when the control component is manually controlled, the clamping component will slide along with the control component, and the transmission wheel at the root of the clamping frame will engage with the guide rod, so that when the clamping component slides through the control component, the clamping frame will swing toward the outer end through the guide rod and the transmission wheel, thereby achieving the effect of the clamping component releasing the reagent tube. On the contrary, after releasing the control component, the clamping frame will swing toward the inner end through the guide component, thereby achieving the clamping effect of the clamping component on the reagent tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solution of the embodiment of the utility model, the drawings of the embodiment will be briefly introduced below.

[0020] The drawings described below only relate to some embodiments of the present invention, but are not intended to limit the present invention.

[0021] In the attached picture:

[0022] Figure 1 The overall structure diagram of the present application is shown;

[0023] Figure 2 A schematic diagram showing the structure of the box assembly of the present application is shown;

[0024] Figure 3 A schematic diagram showing the structure of the sliding assembly of the present application is shown;

[0025] Figure 4 A schematic diagram showing the control component structure of the present application is shown;

[0026] Figure 5 A schematic diagram showing the structure of the clamping assembly of the present application is shown;

[0027] Figure 6 A schematic diagram showing the guide assembly structure of the present application is shown;

[0028] Reference numerals list

[0029] 1. Box assembly; 101. Carrying box; 102. Protective cover; 103. Auxiliary lamp;

[0030] 2. Sliding component; 201. Sliding bar; 202. Sliding block;

[0031] 3. Telescopic assembly; 301. Telescopic rod; 302. External frame; 303. Positioning pin;

[0032] 4. Control assembly; 401. Carrying frame; 402. External board; 403. Sliding frame; 404. Synchronous wheel;

[0033] 5. Clamping assembly; 501. Clamping frame; 502. Clamping wheel; 503. Tension spring;

[0034] 6. Guide assembly; 601. Guide rod; 602. Transmission wheel;

[0035] 7. Reagent tube;

[0036] 8. Reagent bottles. DETAILED DESCRIPTION

[0037] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution of the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings of the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the described embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0038] Example 1: Please refer to Figures 1 to 6 :

[0039] The utility model proposes a cell chromatography device, comprising: a box component 1; a reagent bottle 8 is carried on the box component 1, a sliding component 2 is slidably installed on the inner back side of the box component 1, a telescopic component 3 is installed at the front end position of the sliding component 2, a control component 4 is fixed at the front end position of the telescopic component 3, a clamping component 5 is hingedly installed on the control component 4, a guide component 6 is installed at the position between the root of the clamping component 5 and the control component 4, a reagent tube 7 is clamped and fixed at the position of the clamping component 5, and the bottom of the reagent tube 7 directly extends into the reagent bottle 8.

[0040] In the present disclosure, Figure 2 As shown, the carrying box 101 of the box assembly 1 is configured as a vertical plate frame structure, and protective covers 102 are hingedly installed at both ends of the carrying box 101. An observation surface is provided on the protective cover 102, and the carrying box 101 is directly configured as the main structure for carrying the reagent tubes 7 and the reagent bottles 8. In order to ensure the temperature and environment of the reagent tubes 7 during the experiment, protective covers 102 are directly installed at both ends of the carrying box 101, so that the protective covers 102 can protect the reagent tubes 7 and the reagent bottles 8, and at the same time, the stability of the box assembly 1 as a whole can be ensured, and the observation surface of the protective cover 102 can better observe the inside of the box assembly 1, and an auxiliary light 103 with a vertical structure is provided on the back side of the inner end of the carrying box 101. The auxiliary light 103 is provided on the back panel of the carrying box 101, so that the auxiliary light 103 can directly illuminate the reagent tubes 7 on the box assembly 1, so as to facilitate the observation of the usage of the reagent tubes 7 and increase the effect of the experiment.

[0041] In the present disclosure, Figure 4 As shown, the sliding bar 201 of the sliding component 2 is arranged at the box component 1, and the sliding bar 201 is arranged as three groups of vertical structures. The sliding block 202 is slidably installed on the sliding bar 201, and the sliding block 202 is arranged as a rectangular block structure. The sliding bar 201 is directly arranged on the box component 1, so that the negative sliding block 202 can be stably slidably installed on the sliding bar 201, thereby realizing the stable sliding control of the sliding block 202 on the sliding bar 201, and allowing the sliding component 2 to better slide to achieve the corresponding effect on the length of the reagent tube 7.

[0042] In the present disclosure, Figure 3 As shown, the telescopic rod 301 of the telescopic component 3 is arranged at the front end position of the sliding component 2, and the telescopic rod 301 is set to a horizontal structure. An external frame 302 is slidably installed on the telescopic rod 301, and a positioning pin 303 is installed at the end position of the telescopic rod 301. The external frame 302 is slidably installed at the front end position of the sliding component 2, so that the entire telescopic component 3 can be slidably adjusted, and the front end of the telescopic component 3 can be conveniently and directly adjusted to a specified position, and the inner end of the positioning pin 303 at the end position of the telescopic rod 301 is directly in contact with the external frame 302, so that the positioning pin 303 has the function of controlling the telescopic position of the external frame 302.

[0043] In the present disclosure, Figure 5 As shown, the carrier 401 of the control component 4 is set to a rectangular frame structure, and two groups of synchronous wheels 404 are rotatably installed in the carrier 401. A sliding frame 403 is slidably installed at the position of the synchronous wheel 404 of the carrier 401. The sliding frame 403 is set to two groups symmetrical in the center of a circle, and each group of sliding frames 403 is meshed with the synchronous wheel 404. An external plate 402 is set at the outer end position of the sliding frame 403, and an anti-slip strip is set on the outer end surface of the external plate 402. When the control component 4 is in use, the external plate 402 at one side is directly pressed to allow the external plate 402 to drive the sliding frame 403 to slide, so that the two groups of symmetrical sliding frames 403 can move synchronously through the two groups of synchronous wheels 404, thereby achieving the external plate 402 from one side while allowing the external plates 402 at both ends to move synchronously, which is convenient for direct control of the control component 4, and the anti-slip groove at the outer end of the external plate 402 has a corresponding anti-slip effect when in contact.

[0044] In the present disclosure, Figure 5 Figure 6 As shown, the clamping frame 501 of the clamping assembly 5 is hingedly installed at the inner end position of the external plate 402, and a clamping wheel 502 is rotatably installed at the end position of each group of clamping frames 501, and a tension spring 503 is installed between the upper and lower clamping frames 501. The tension spring 503 is connected to the upper and lower clamping frames 501, so that the clamping frame 501 can be stably swung toward the inner end through the tension spring 503, and the clamping wheel 502 of the clamping frame 501 can be directly clamped on the reagent tube 7, so that the clamping assembly 5 can clamp the reagent tube 7, and the clamping wheel 502 at the end position of the clamping frame 501 is convenient for the clamping wheel 502 to directly contact the reagent tube 7, so as to achieve a stable contact between the clamping assembly 5 and the reagent tube 7.

[0045] Embodiment 2, based on embodiment 1, as Figure 6As shown, the guide rod 601 of the guide component 6 is arranged at both ends of the carrier frame 401, and the guide rod 601 extends toward the outer end. The root of the clamping frame 501 on the control component 4 is arranged near the guide rod 601 as a transmission wheel 602, and the transmission wheel 602 is directly engaged with the guide rod 601. When the control component 4 is manually controlled, the clamping component 5 will slide along with the control component 4, and the transmission wheel 602 at the root position of the clamping frame 501 will engage with the guide rod 601, so that when the clamping component 5 slides through the control component 4, the clamping frame 501 passes through the guide rod 601 and the transmission wheel 602, so that the net clamping frame 501 swings toward the outer end, and the clamping component 5 releases the reagent tube 7. On the contrary, after the control component 4 is released, the clamping frame 501 will swing toward the inner end through the guide component 6, so that the clamping component 5 clamps the reagent tube 7.

[0046] The working principle of this embodiment is as follows: during installation, the protective cover 102 of the carrying box 101 is first swung open toward the two sides. At this time, the size and height of the reagent tube 7 are observed according to the situation, and the sliding component 2 is slid up and down on the box component 1 so that the sliding component 2 slides to the specified position. According to the required conditions, the telescopic component 3 of the sliding component 2 is telescopically adjusted. At this time, the control component 4 at the front end of the telescopic component 3 is manually controlled, and the hand-touching external plate 402 will allow the synchronous wheel 404 to synchronously control the two sets of sliding frames 403, directly realizing direct control of the control component 4 from one side. A clamping component 5 is installed on the external plate 402, and a guide component 6 is installed at the root of the clamping component 5 near the control component 4. While controlling the control component 4, the guide component 6 controls the swing of the clamping component 5, so that after the hand-touching control component 4 controls the clamping component 5 toward both ends, the guide component 6 swings the clamping component 5 toward the outer end, thereby realizing a better clamping effect of the device on the reagent tube 7.

[0047] In this article, there are a few points to note:

[0048] 1. The drawings of the embodiments of the present disclosure only involve structures related to the embodiments of the present disclosure, and other structures may refer to general designs.

[0049] 2. In the absence of conflict, the embodiments of the present disclosure and the features therein may be combined with each other to obtain new embodiments.

[0050] The above are only specific embodiments of the present disclosure, but the protection scope of the present disclosure is not limited thereto. Any technician familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present disclosure, which should be included in the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure should be based on the protection scope of the claims.

Claims

1. A cell chromatography device, comprising: A box assembly (1); the box assembly (1) carries a reagent bottle (8), characterized in that a sliding assembly (2) is slidably installed on the inner back of the box assembly (1), a telescopic assembly (3) is installed at the front end of the sliding assembly (2), a control assembly (4) is fixed at the front end of the telescopic assembly (3), a clamping assembly (5) is hingedly installed on the control assembly (4), a guide assembly (6) is installed at a position between the root of the clamping assembly (5) and the control assembly (4), a reagent tube (7) is clamped and fixed at the position of the clamping assembly (5), and the bottom of the reagent tube (7) directly extends into the reagent bottle (8).

2. A cell chromatography device according to claim 1, characterized in that: The carrying box (101) of the box assembly (1) is configured as a vertical plate frame structure, and protective covers (102) are hingedly installed at both ends of the carrying box (101). The protective cover (102) is provided with an observation surface, and the carrying box (101) is directly configured as the main structure for carrying the reagent tube (7) and the reagent bottle (8). An auxiliary light (103) of a vertical structure is provided on the back surface of the inner end of the carrying box (101).

3. A cell chromatography device according to claim 1, characterized in that: The sliding bars (201) of the sliding assembly (2) are arranged at the box assembly (1), the sliding bars (201) are arranged as three groups of vertical structures, sliding blocks (202) are slidably mounted on the sliding bars (201), and the sliding blocks (202) are arranged as rectangular block structures.

4. A cell chromatography device according to claim 1, characterized in that: The telescopic rod (301) of the telescopic assembly (3) is arranged at the front end of the sliding assembly (2); the telescopic rod (301) is arranged as a horizontal structure; an external frame (302) is slidably mounted on the telescopic rod (301); and a positioning pin (303) is mounted at the end of the telescopic rod (301).

5. A cell chromatography device according to claim 1, characterized in that: The support frame (401) of the control component (4) is arranged in a rectangular frame structure. Two groups of synchronous wheels (404) are rotatably mounted in the support frame (401). A sliding frame (403) is slidably mounted at the position of the synchronous wheels (404) of the support frame (401). The sliding frames (403) are arranged in two groups symmetrically with respect to the center of a circle. Each group of sliding frames (403) is meshed with the synchronous wheels (404). An external connection plate (402) is arranged at the outer end of the sliding frame (403), and an anti-slip strip is arranged on the outer end surface of the external connection plate (402).

6. A cell chromatography device according to claim 1, characterized in that: The clamping frames (501) of the clamping assembly (5) are hingedly mounted at the inner end of the external plate (402), a clamping wheel (502) is rotatably mounted at the end of each set of clamping frames (501), and a tension spring (503) is installed between the upper and lower clamping frames (501).

7. A cell chromatography device according to claim 1, characterized in that: The guide rods (601) of the guide assembly (6) are arranged at both ends of the carrier frame (401), and the guide rods (601) extend toward the outer ends. A transmission wheel (602) is arranged at the root of the clamping frame (501) on the control assembly (4) near the guide rods (601), and the transmission wheel (602) is directly meshed with the guide rods (601).