Instrument capable of incubating and detecting two-step colloidal gold test strip

Abstract

The utility model relates to the technical field of food safety detection, and discloses an instrument capable of incubating and detecting a two-step colloidal gold test strip, which comprises a base, the upper surface of the base is fixedly connected with a plurality of slide rails, and the upper ends of the slide rails are connected with bottom incubation modules in a sliding manner. According to the utility model, when the instrument for incubating and detecting the two-step colloidal gold test strip is used, the integrated operation of incubating and detecting the two-step colloidal gold test strip is realized, the result error possibly generated by manual intervention is completely avoided, the detection flux of the instrument is high, and the detection accuracy is high. The two-step method test strip incubator can support at most 12 two-step method test strips to perform incubation and detection at the same time, independent module temperature control can meet the requirements of different incubation temperatures, and the detection module comprises a linear scanning light source, a silicon photodiode and a CCD camera and can be compatible with scanning method detection and photographing method detection.

Description

Technical Field

[0001] The utility model relates to the technical field of food safety detection, in particular to an instrument capable of incubating and detecting a two-step colloidal gold test strip. Background Art

[0002] Currently, there is no incubation and detection machine for two-step test strips on the market. Two-step test strips require manual insertion of the test strips into the reagent and reaction in a special incubator. After the reaction is completed, the test strips are taken out and inserted into a special reader for qualitative or quantitative analysis. Description: How to use the two-step test strips: mix the analyte with the reagent, incubate at a constant temperature for timing, when the timing is over, insert the test strip into the mixed reagent, and incubate the test strip and the reagent at the same time for timing, when the timing is over, take out the test strip and insert it into the reader for qualitative or quantitative analysis. The instrument described in this patent only needs to mix the analyte with the reagent and put it into the bottom incubation module; after the test strip is inserted into the back incubation module, the incubation time is set by the software, and two incubations and qualitative or quantitative analysis can be automatically completed. Utility Model Content

[0003] The purpose of the utility model is to solve the shortcomings existing in the prior art, and to propose an instrument that can incubate and detect two-step colloidal gold test strips. When the instrument for incubating and detecting two-step colloidal gold test strips is used, the incubation and detection of the two-step colloidal gold test strips are integrated, and the result errors that may be caused by human intervention are completely avoided. The instrument has a high detection throughput and can support up to 12 two-step test strips for incubation and detection at the same time. The independent module temperature control can meet the needs of different incubation temperatures. The detection module includes a linear scanning light source, a silicon photodiode and a CCD camera, which is compatible with scanning detection and photographing detection. During back incubation, the angle of the test strip inserted into the reagent can be adjusted, and the bottom incubation block can be taken out independently, which is easy to clean and operate. The temperature control accuracy is high and can reach ±0.1°C.

[0004] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0005] An instrument capable of incubating and detecting a two-step colloidal gold test strip comprises a base, the upper surface of the base is fixedly connected with a plurality of slide rails, the upper ends of the slide rails are slidably connected with a bottom incubation module, the rear ends of the upper surfaces of the bottom incubation modules are provided with incubation grooves, the bottom surface of the incubation grooves is provided with a reagent incubation module, the front end of the upper surface of the base is bolted with a plurality of connection frames, and both sides of the rear end of the upper surface of the base are bolted with a detection module transmission motor;

[0006] The outer walls of the connecting frames on both sides away from the center of the base are rotatably connected with screw rods, and the rod bodies of the screw rods on both sides are sleeved with detection modules. Back lifting support plates are bolted to both sides of the middle of the upper surface of the base, and multiple back lifting motors are bolted to the upper ends of the back lifting support plates. Angle adjustment knobs are provided on both sides of the outer wall at the rear end of the back lifting support plate.

[0007] Through the above technical scheme, compared with the existing two-step colloidal gold test strip incubation and detection instrument, when the two-step colloidal gold test strip incubation and detection instrument is used, the linear scanning and CCD camera are shared to assist in improving the detection accuracy. The integrated incubation and detection of the two-step colloidal gold test strip can greatly reduce the operation of personnel, and the incubation and detection are carried out inside the instrument to avoid the error of the detection result caused by external contamination, and solve the position error of the two-step colloidal gold test strip after manual insertion and incubation, which will have an adverse effect on the detection result. The high-throughput design can realize the incubation and detection of 12 two-step colloidal gold test strips by a single instrument at the same time. The design of two sets of detection modules can realize the qualitative or quantitative analysis of 6 two-step colloidal gold test strips within 15 seconds, thereby solving the time difference caused by the need for manual picking of the incubated test strips and testing of the two-step test strips, maximizing the detection consistency, and having high practical performance.

[0008] Furthermore, one side of the screw rod near the center of the base penetrates through the two side connecting frames and is rotatably connected to the outer wall of the middle connecting frame, and the rod body of the screw rod and the output end of the detection module transmission motor are both sleeved with transmission gears;

[0009] Through the above technical solution, the detection module is started to drive the motor to rotate, thereby driving the rear end transmission gear to rotate.

[0010] Furthermore, the outer walls of the transmission gears are sleeved with transmission toothed belts, and the transmission toothed belts are meshed with the transmission gears;

[0011] Through the above technical solution, the transmission toothed belt is meshed with the transmission gear, so as to drive the transmission toothed belt and the lead screw to move.

[0012] Furthermore, one side of the connecting frames on both sides close to the center of the base is fixedly connected with a guide rod, and the guide rod passes through the detection module and is fixedly connected to the outer wall of the middle connecting frame;

[0013] Through the above technical solution, the detection module is easily limited by the guide rod, so that the detection modules on both sides are driven to move horizontally through the rotation of the screw rod to analyze and detect the test strips at each confirmed position.

[0014] Furthermore, a linear scanning module and a CCD camera are respectively arranged inside the detection module;

[0015] Through the above technical solution, the test strip after the reaction is completed can be photographed and analyzed by the CCD camera, and the one-dimensional code or two-dimensional code on the test strip can also be photographed to identify product information. The fixed-wavelength LED light and silicon photodiode inside the linear scanning module can be used to perform scanning analysis on the two-step colloidal gold test strip.

[0016] Furthermore, the output end of the back lifting motor is sleeved with an incubation connection plate, and both sides of the rear end outer wall of the incubation connection plate are slidably connected to the outer wall of the front end of the back lifting support plate;

[0017] Through the above technical solution, the back lifting support plate is convenient for improving the coordination.

[0018] Furthermore, both sides of the front inner wall of the incubation connection plate are fixedly connected with back incubation modules;

[0019] Through the above technical solution, heating is performed by the polyamide heating film inside the back incubation module, temperature is collected using a thermistor, and temperature control is facilitated by a control circuit board.

[0020] Furthermore, a control circuit board is provided at the rear of the upper end of the base;

[0021] Through the above technical solution, the control circuit board can be easily installed inside the control cabinet, and the control circuit board can be easily electrically connected to the detection module transmission motor and the back lifting motor to control their switching and strength.

[0022] The utility model has the following beneficial effects:

[0023] 1. The utility model proposes an instrument for incubating and detecting two-step colloidal gold test strips. Compared with the existing instruments for incubating and detecting two-step colloidal gold test strips, the instrument for incubating and detecting two-step colloidal gold test strips realizes the integrated operation of incubation and detection of two-step colloidal gold test strips when used, completely avoiding the result errors that may be caused by human intervention. The instrument has a high detection throughput and can support up to 12 two-step test strips for incubation and detection at the same time. The independent module temperature control can meet the needs of different incubation temperatures. The detection module includes a linear scanning light source, a silicon photodiode and a CCD camera, which is compatible with scanning detection and photographing detection. During back incubation, the angle of the test strip inserted into the reagent can be adjusted, and the bottom incubation block can be taken out independently, which is easy to clean and operate. The temperature control accuracy is high and can reach ±0.1°C.

[0024] 2. The utility model proposes an instrument for incubating and detecting a two-step colloidal gold test strip. Compared with the existing two-step colloidal gold test strip incubation and detection instrument, the two-step colloidal gold test strip incubation and detection instrument can help improve the detection accuracy through the use of linear scanning and CCD camera. The integrated incubation and detection of the two-step colloidal gold test strip can greatly reduce the operation of personnel, and the incubation and detection are carried out inside the instrument to avoid the error of the detection result caused by external contamination, which solves the problem. The position error of the two-step colloidal gold test strips after manual insertion and incubation will have an adverse effect on the test results. The high-throughput design can enable a single instrument to incubate and test 12 two-step colloidal gold test strips at the same time. The design of two sets of detection modules can complete the qualitative or quantitative analysis of 6 two-step colloidal gold test strips within 15 seconds, thus solving the time difference caused by the need for manual removal of the incubated test strips and testing of the two-step test strips, maximizing the detection consistency and having high practical performance. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 This is an axonometric diagram of an instrument for incubating and detecting a two-step colloidal gold test strip proposed by the utility model;

[0026] Figure 2 This is an axonometric schematic diagram of an instrument for incubating and detecting a two-step colloidal gold test strip proposed by the utility model;

[0027] Figure 3 This is a schematic diagram of the structure of a linear scanning module in an instrument for incubating and detecting a two-step colloidal gold test strip proposed by the utility model;

[0028] Figure 4 It is a side view of an instrument for incubating and detecting a two-step colloidal gold test strip proposed by the utility model;

[0029] Figure 5 This is a front view of an instrument for incubating and detecting a two-step colloidal gold test strip proposed by the utility model;

[0030] Figure 6 The utility model is a rear view of an instrument for incubating and detecting a two-step colloidal gold test strip.

[0031] 1. Base; 2. Slide rail; 3. Bottom incubation module; 4. Incubation tank; 5. Reagent incubation module; 6. Connecting frame; 7. Detection module transmission motor; 8. Transmission gear; 9. Transmission belt; 10. Screw rod; 11. Detection module; 12. Back lifting support plate; 13. Back lifting motor; 14. Incubation connecting plate; 15. Back incubation module; 16. Angle adjustment knob; 17. Linear scanning module; 18. CCD camera; 19. Control circuit board; 20. Guide rod. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0033] Reference Figure 1-6 The utility model provides an embodiment: an instrument for incubating and detecting a two-step colloidal gold test strip, comprising a base 1, a plurality of slide rails 2 are fixedly connected to the upper surface of the base 1, the upper ends of the slide rails 2 are slidably connected to a bottom incubation module 3, the rear ends of the upper surfaces of the bottom incubation modules 3 are provided with incubation grooves 4, the bottom surface of the incubation grooves 4 is provided with reagent incubation modules 5, the front end of the upper surface of the base 1 is bolted to a plurality of connecting frames 6, and both sides of the rear end of the upper surface of the base 1 are bolted to a detection module transmission motor 7;

[0034] The outer walls of the two side connecting frames 6 away from the center of the base 1 are rotatably connected with screw rods 10, and the rod bodies of the screw rods 10 on both sides are sleeved with detection modules 11. The two sides of the middle part of the upper surface of the base 1 are bolted with back lifting support plates 12, and the upper ends of the back lifting support plates 12 are bolted with multiple back lifting motors 13, and angle adjustment knobs 16 are provided on both sides of the outer wall of the rear end of the back lifting support plate 12.

[0035] Compared with the existing two-step colloidal gold test strip incubation and detection instrument, when the two-step colloidal gold test strip incubation and detection instrument is used, the linear scanning and CCD camera 18 are shared to help improve the detection accuracy. The integrated incubation and detection of the two-step colloidal gold test strip can greatly reduce the operation of personnel, and the incubation and detection are carried out inside the instrument to avoid the error of the detection result caused by external pollution, and solve the position error of the two-step colloidal gold test strip after manual insertion and incubation, which will have an adverse effect on the detection result. The high-throughput design can realize the incubation and detection of 12 two-step colloidal gold test strips by a single instrument at the same time. The design of two sets of detection modules 11 can realize the qualitative or quantitative analysis of 6 two-step colloidal gold test strips within 15 seconds, thereby solving the time difference caused by the need for manual picking of the incubated test strips and testing of the two-step test strips, maximizing the detection consistency, and having high practical performance.

[0036] The side of the screw rod 10 near the center of the base 1 passes through the connecting frames 6 on both sides and is rotatably connected to the outer wall of the middle connecting frame 6. The rod body of the screw rod 10 and the output end of the detection module transmission motor 7 are sleeved with a transmission gear 8. By starting the detection module transmission motor 7 to rotate, it is convenient to drive the rear end transmission gear 8 to rotate. The outer wall of the transmission gear 8 is sleeved with a transmission toothed belt 9, and the transmission toothed belt 9 is meshed with the transmission gear 8. The transmission toothed belt 9 is meshed with the transmission gear 8 to facilitate the transmission toothed belt 9 and the screw rod 10 to move. The side of the connecting frames 6 on both sides near the center of the base 1 is fixedly connected with a guide rod 20. The guide rod 20 passes through the detection module 11 and is fixedly connected to the outer wall of the middle connecting frame 6. The guide rod 20 is convenient for limiting the detection module 11, so that the detection modules 11 on both sides are driven to move horizontally by the rotation of the screw rod 10, which is used to analyze and detect the test strips at each confirmed position. The interior of the detection module 11 is respectively provided with a linear scanning module 17 and a CCD camera 18. Through the CCD camera 18 can take photos and analyze the test strips after the reaction is completed, and can also take photos of the one-dimensional code or two-dimensional code on the test strips to identify product information. The fixed-wavelength LED lamp and silicon photodiode inside the linear scanning module 17 can be used to scan and analyze the two-step colloidal gold test strips. The output end of the back lifting motor 13 is sleeved with an incubation connecting plate 14. Both sides of the outer wall of the rear end of the incubation connecting plate 14 are slidably connected to the outer wall of the front end of the back lifting support plate 12. The back lifting support plate is convenient for improving coordination. Both sides of the inner wall of the front end of the incubation connecting plate 14 are fixedly connected with a back incubation module 15. The polyamide heating film inside the back incubation module 15 is used for heating, and the temperature is collected using a thermistor. The temperature is conveniently controlled by the control circuit board 19. The rear part of the upper end of the base 1 is provided with a control circuit board 19, which is convenient for installation inside the control cabinet. The control circuit board 19 is convenient for electrical connection with the detection module transmission motor 7 and the back lifting motor 13, thereby controlling its switch and intensity.

[0037] Working principle: when in use, place the microwell with the reagent in the reagent incubation module 5, and then put the reagent incubation module 5 into the bottom incubation module 3, so as to achieve the purpose of incubating the reagent, heat it through the polyamide heating film inside the bottom incubation module 3, and collect temperature through the internal thermistor, and control the temperature through the control circuit board 19, and pull the whole body through the slide rail 2, so as to pull out or push the bottom incubation module 3 to the normal working position, and control the rotation of the bottom incubation module 3 by electrically connecting it with the monitoring module transmission motor through the control circuit board 19, and drive the transmission gear 8 and the transmission toothed belt 9 to rotate by rotating the detection module transmission motor 7, and drive the front transmission gear 8 to rotate by rotating the toothed belt, and drive the screw 10 to rotate at the same time, and limit the screw 10 through the guide rod 20, so that the detection modules 11 on both sides can move laterally respectively, so as to facilitate the analysis and detection of the test strips at each confirmed position, and the CCD camera 18 can be used for The test strip after the reaction is completed can be photographed and analyzed, and the one-dimensional code or two-dimensional code on the test strip can also be photographed to identify product information. The fixed-wavelength LED light and silicon photodiode built into the linear scanning module 17 facilitate scanning analysis of the two-step colloidal gold test strip. The back incubation module 15 is heated by the internal polyamide heating film, and the temperature is collected by the thermistor. The temperature is controlled by the control circuit board 19. The test strip can be inserted into the back incubation module 15. The jammer can hold up to three two-step colloidal gold test strips in the jammer, and the back lifting motor 13 rotates to drive the back incubation module 15 to move up and down. When the jammer with the two-step colloidal gold test strip is inserted into the back incubation module 15, as the back lifting motor 13 rotates, the back incubation module 15 will insert the two-step colloidal gold test strip downward into the microwell. When the reaction is completed, the back lifting motor 13 rotates in the opposite direction to lift the back incubation module 15, thereby stopping the incubation and the chromatography reaction of the test strip.

[0038] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. An instrument for incubating and detecting a two-step colloidal gold test strip, comprising a base (1), characterized in that: The upper surface of the base (1) is fixedly connected to a plurality of slide rails (2), the upper ends of the slide rails (2) are slidably connected to a bottom incubation module (3), the rear ends of the upper surfaces of the bottom incubation modules (3) are provided with incubation grooves (4), the bottom surface of the incubation grooves (4) is provided with reagent incubation modules (5), the front end of the upper surface of the base (1) is bolted to a plurality of connection frames (6), and both sides of the rear end of the upper surface of the base (1) are bolted to a detection module transmission motor (7); The outer walls of the connecting frames (6) on both sides away from the center of the base (1) are rotatably connected to a screw rod (10), and the rod bodies of the screw rods (10) on both sides are sleeved with detection modules (11). The middle part of the upper surface of the base (1) is bolted to a back lifting support plate (12) on both sides, and the upper ends of the back lifting support plates (12) are bolted to a plurality of back lifting motors (13), and angle adjustment knobs (16) are provided on both sides of the rear end outer wall of the back lifting support plate (12).

2. The apparatus for incubating and detecting a two-step colloidal gold test strip according to claim 1, characterized in that: One side of the screw rod (10) close to the center of the base (1) passes through the connecting frames (6) on both sides and is rotatably connected to the outer wall of the middle connecting frame (6). The rod body of the screw rod (10) and the output end of the detection module transmission motor (7) are both sleeved with a transmission gear (8).

3. The apparatus for incubating and detecting a two-step colloidal gold test strip according to claim 2, characterized in that: The outer walls of the transmission gears (8) are sleeved with transmission toothed belts (9), and the transmission toothed belts (9) are meshed with the transmission gears (8).

4. The apparatus for incubating and detecting a two-step colloidal gold test strip according to claim 1, characterized in that: A guide rod (20) is fixedly connected to one side of the connecting frames (6) on both sides near the center of the base (1); the guide rod (20) passes through the detection module (11) and is fixedly connected to the outer wall of the middle connecting frame (6).

5. The apparatus for incubating and detecting a two-step colloidal gold test strip according to claim 1, characterized in that: A linear scanning module (17) and a CCD camera (18) are respectively arranged inside the detection module (11).

6. The apparatus for incubating and detecting a two-step colloidal gold test strip according to claim 1, characterized in that: An incubation connection plate (14) is sleeved on the output end of the back lifting motor (13), and both sides of the rear end outer wall of the incubation connection plate (14) are slidably connected to the front end outer wall of the back lifting support plate (12).

7. The apparatus for incubating and detecting a two-step colloidal gold test strip according to claim 6, characterized in that: Back incubation modules (15) are fixedly connected to both sides of the front inner wall of the incubation connection plate (14).

8. The apparatus for incubating and detecting a two-step colloidal gold test strip according to claim 1, characterized in that: A control circuit board (19) is provided at the rear of the upper end of the base (1).

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