Concentrated solution mixing device for levetiracetam injection

Abstract

The utility model discloses a concentrated solution mixing device for injection of levetiracetam. The device comprises an outer shell and an inner shell arranged on the upper side in the outer shell, the outer side of the inner shell and the inner side of the outer shell are arranged in a spaced mode, heating water is arranged in the outer shell, the lower end of the inner shell is arranged on the upper side of a grid plate, the grid plate is detachably and fixedly connected to the inner side of the outer shell, and the grid plate and the outer shell are spaced to form a heating cavity. A heating resistor and a temperature sensor are arranged in the heating cavity, a stirring mechanism is arranged in the middle of the lower side of the outer shell, and the heating resistor, the temperature sensor and the stirring mechanism are all connected with the main controller. According to the utility model, the temperature of water for injection in the inner shell can be increased, so that levetiracetam, sodium chloride and the like can be quickly dissolved, and subsequent direct electrochemical treatment is facilitated; by arranging the stirring mechanism, the heated water heated by the resistor is quickly diffused outwards, so that the temperature of the heated water in the outer side area of the inner shell is relatively uniform, and meanwhile, the heating efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of mixing devices, in particular to a concentrated solution mixing device for levetiracetam injection. Background Art

[0002] Levetiracetam is an anti-epileptic drug that can be taken orally or by injection. Oral medication is divided into tablets and oral solution, while injection medication is a concentrated solution diluent. When preparing a concentrated solution of levetiracetam for injection, the prescribed amount of levetiracetam, water for injection, sodium chloride and other raw and auxiliary materials must first be stirred and mixed so that levetiracetam, sodium chloride, etc. can be fully dissolved. The existing mixing process is generally carried out at room temperature, and the dissolution rate of levetiracetam, sodium chloride, etc. will be slightly lower, and the corresponding dissolution time will be longer. In addition, when the concentrated solution is electrochemically treated after mixing, the concentrated solution temperature also needs to be heated to 50-60°C. If the temperature of the solution is increased during mixing, it is not only possible to increase the dissolution rate of levetiracetam, sodium chloride, etc., but also facilitate direct electrochemical treatment of the mixed concentrated solution. Utility Model Content

[0003] The utility model aims to provide a levetiracetam concentrated solution mixing device for injection in view of the deficiencies in the prior art.

[0004] To achieve the above-mentioned purpose, the utility model provides a levetiracetam concentrated solution mixing device for injection, comprising an outer shell and an inner shell arranged on the upper side of the inner shell, the outer side of the inner shell is spaced apart from the inner side of the outer shell, heating water is provided in the outer shell, and a plurality of legs are provided around the lower side thereof, the lower end of the inner shell is provided on the upper side of a grate plate, the grate plate is detachably fixedly connected to the inner side of the outer shell, the grate plate and the outer shell are spaced apart to form a heating chamber, a heating resistor and a temperature sensor are provided in the heating chamber, a stirring mechanism is provided in the middle of the lower side of the outer shell, and the heating resistor, the temperature sensor and the stirring mechanism are all connected to a main controller.

[0005] Furthermore, the stirring mechanism includes a motor arranged in the middle of the lower side of the outer shell, the rotating shaft of the motor is fixedly connected to the connecting shaft, the connecting shaft bearing is connected to the outer shell, and a shaft seal is provided between it and the outer shell, the upper end of the connecting shaft passes through the outer shell and is arranged in the heating chamber, and the upper end of the connecting shaft is fixedly connected to a stirring blade.

[0006] Furthermore, the stirring blade comprises a connecting sleeve sleeved on the outer side of the upper end of the connecting shaft, the upper end of the connecting shaft is threadedly connected with a locking bolt, and two blades arranged in a spiral interval are fixed to the outer side of the connecting sleeve.

[0007] Furthermore, a limiting groove is provided at the lower end of the connecting sleeve, and a limiting block cooperating with the limiting groove is provided on the connecting shaft.

[0008] Furthermore, a connecting seat is fixedly connected to the middle portion of the lower side of the outer shell, and the motor is fixed on the connecting seat.

[0009] Furthermore, the heating resistors are arranged in a coiled manner at intervals on the outer circumference of the stirring blade.

[0010] Furthermore, the inner shell is in the shape of an inverted frustum.

[0011] Furthermore, the main controller is fixedly arranged on the outside of the outer shell.

[0012] Beneficial effects: The utility model arranges an inner shell in an outer shell, and the inner shell is surrounded by heating water in the outer shell, so that after the heating water is heated by a heating resistor, the injection water in the inner shell is heated by a water bath, thereby increasing the temperature of the injection water, facilitating the rapid dissolution of levetiracetam, sodium chloride, etc., and facilitating subsequent direct electrochemical treatment; by arranging a stirring mechanism, the heating water heated by the resistor is quickly diffused outward, so that the temperature of the heating water in the outer area of ​​the inner shell is relatively uniform, and the heating efficiency is improved at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a schematic diagram of the three-dimensional structure of a mixing device for a concentrated solution of levetiracetam for injection;

[0014] Figure 2 It is a schematic cross-sectional view of a mixing device for a concentrated solution of levetiracetam for injection;

[0015] Figure 3 It is a schematic diagram of the three-dimensional structure of the stirring blade of the embodiment of the utility model. DETAILED DESCRIPTION

[0016] The present invention is further explained below in conjunction with the accompanying drawings and specific embodiments. The embodiments are implemented based on the technical solution of the present invention. It should be understood that these embodiments are only used to illustrate the present invention and are not used to limit the scope of the present invention.

[0017] like Figures 1 to 3As shown, the embodiment of the utility model provides a levetiracetam concentrated solution mixing device for injection, including an outer shell 1 and an inner shell 2, the inner shell 2 is arranged on the upper side of the inner shell 1, and the outer side of the inner shell 2 is arranged at intervals from the inner side of the outer shell 1. Heating water is provided inside the outer shell 1. When the liquid level of the heating water is reduced, it is necessary to add heating water to the outer shell 1, and the inner shell 2 can be removed to add water. The outer shell 2 is preferably arranged in an inverted truncated cone shape, and the inner shell 2 is used to put the injection water to be mixed into the agricultural solution. The outer side of the inner shell 2 is surrounded by heating water, and the heat of the heating water can be conducted to the injection water through the inner shell 2, thereby heating the injection water in the inner shell 2. A plurality of legs 3 are arranged around the lower side of the outer shell 1, and the legs 3 are preferably 3. The lower end of the inner shell 2 is arranged on the upper side of the grate plate 4, and the grate plate 4 is detachably fixedly connected to the inner side of the outer shell 1, and the grate holes on the grate plate 4 can make the heating water on both sides of it flow. The grate plate 4 is spaced apart from the outer shell 1 to form a heating chamber 5, in which a heating resistor 6 and a temperature sensor are arranged. A stirring mechanism is arranged in the middle of the lower side of the outer shell 1, and the stirring mechanism can stir the heating water in the outer shell 1 so that the temperature of the heating water around the inner shell 2 is basically the same. The above-mentioned heating resistor 6, temperature sensor and stirring mechanism are all connected to the main controller 7. The main controller 7 is preferably fixedly arranged on the outside of the outer shell 1, and the main controller 7 controls the heating resistor 6 to work according to the temperature sensor, so that the temperature of the heating water is kept within a set range. When the controller 7 controls the heating resistor 6 to work, it synchronously controls the stirring mechanism to work.

[0018] The stirring mechanism of the embodiment of the utility model comprises a motor 13, which is arranged at the middle part of the lower side of the outer shell 1, and the rotating shaft of the motor 13 is fixedly connected to the connecting shaft 8, preferably by a coupling 9. The connecting shaft 8 is connected to the outer shell 1 by a bearing, and can rotate freely relative to the outer shell 1. A shaft seal is also provided between the connecting shaft 8 and the outer shell 1 to prevent leakage of the heated water. The upper end of the connecting shaft 8 is arranged in the heating chamber 5 through the outer shell 1, and a stirring blade 10 is fixedly connected to the upper end of the connecting shaft 8. The heating resistor 6 of the embodiment of the utility model is preferably arranged at intervals and coiled on the periphery of the stirring blade 10. The stirring blade 10 comprises a connecting sleeve 101 and a blade 102, wherein the connecting sleeve 101 is sleeved on the outer side of the upper end of the connecting shaft 8, and a locking bolt 11 is threadedly connected to the upper end of the connecting shaft 8, and the connecting sleeve 101 is fixed to the connecting shaft 8 by the locking bolt 11. The blade 102 is preferably two, and it is arranged at a spiral interval and fixed to the outer side of the connecting sleeve 101 by welding. It is also preferred that a limiting groove is provided at the lower end of the connecting sleeve 101 , and a limiting block 81 cooperating with the limiting groove is provided on the connecting shaft 8 , so as to ensure that the connecting sleeve 101 and the connecting shaft 8 rotate synchronously.

[0019] In order to facilitate the installation of the motor 13, a connection seat 12 is fixedly connected to the middle of the lower side of the outer shell 1, and the connection seat specifically includes an upper connection plate 121, a lower connection plate 122, and a plurality of pillars 123 fixed between the upper connection plate 121 and the lower connection plate 122. The upper connection plate 121 and the lower connection plate 122 are both annular structures, and the middle part can be used for the rotation shaft and the connecting shaft 8 of the motor 13 to pass through. The upper connection plate 121 is preferably fixed to the outer shell 1 by a plurality of bolts, and the motor 13 is preferably fixed to the lower connection plate 122 by a plurality of bolts.

[0020] The above is only a preferred embodiment of the utility model. It should be pointed out that for ordinary technicians in this technical field, other parts not specifically described belong to the prior art or common knowledge. Under the premise of not departing from the principle of the utility model, several improvements and modifications can be made, and these improvements and modifications should also be regarded as the protection scope of the utility model.

Claims

1. A levetiracetam concentrated solution mixing device for injection, characterized in that: It includes an outer shell and an inner shell arranged on the upper side of the outer shell, the outer side of the inner shell is spaced apart from the inner side of the outer shell, heating water is arranged in the outer shell, and a plurality of legs are arranged around the lower side thereof, the lower end of the inner shell is arranged on the upper side of a grate plate, the grate plate is detachably fixedly connected to the inner side of the outer shell, the grate plate and the outer shell are spaced apart to form a heating chamber, a heating resistor and a temperature sensor are arranged in the heating chamber, a stirring mechanism is arranged in the middle of the lower side of the outer shell, and the heating resistor, the temperature sensor and the stirring mechanism are all connected to a main controller.

2. A levetiracetam concentrated solution mixing device for injection according to claim 1, characterized in that: The stirring mechanism includes a motor arranged in the middle of the lower side of the outer shell, the rotating shaft of the motor is fixedly connected to the connecting shaft, the connecting shaft bearing is connected to the outer shell, and a shaft seal is provided between the connecting shaft and the outer shell, the upper end of the connecting shaft passes through the outer shell and is arranged in the heating chamber, and the upper end of the connecting shaft is fixedly connected to a stirring blade.

3. A levetiracetam concentrated solution mixing device for injection according to claim 2, characterized in that: The stirring blade comprises a connecting sleeve sleeved on the outer side of the upper end of the connecting shaft, the upper end of the connecting shaft is threadedly connected with a locking bolt, and two blades arranged in a spiral interval are fixed on the outer side of the connecting sleeve.

4. A levetiracetam concentrated solution mixing device for injection according to claim 3, characterized in that: A limiting groove is arranged at the lower end of the connecting sleeve, and a limiting block matched with the limiting groove is arranged on the connecting shaft.

5. A levetiracetam concentrated solution mixing device for injection according to claim 2, characterized in that: A connecting seat is fixedly connected to the middle part of the lower side of the outer shell, and the motor is fixed on the connecting seat.

6. A levetiracetam concentrated solution mixing device for injection according to claim 2, characterized in that: The heating resistors are coiled and arranged at intervals on the outer circumference of the stirring blade.

7. A levetiracetam concentrated solution mixing device for injection according to claim 2, characterized in that: The inner shell is in an inverted frustum shape.

8. A levetiracetam concentrated solution mixing device for injection according to claim 2, characterized in that: The main controller is fixedly arranged on the outside of the outer shell.

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