Bottom cantilever shaft distributed bearing supporting structure
By adopting the bottom cantilever shaft distributed bearing support structure in the stirring mechanism of the disposable bag bioreactor, the problem of high requirements for container installation conditions in the prior art is solved, stable fixation under low installation conditions is achieved, suitable for use of flexible bag bodies, and operation stability is improved.
Patent Information
- Application Number
- CN202421833508.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-30
- Publication Date
- 2025-05-30
- Estimated Expiration
- 2034-07-30
AI Technical Summary
The stirring mechanism of existing disposable bag bioreactors has high requirements for container installation conditions, and requires both ends of the stirring shaft to be fixed, resulting in complex installation and high requirements for rigid support containers.
The bottom cantilever shaft distributed bearing support structure is adopted. By setting a movable assembly and multiple bearings at one end of the shaft body, and locking the bearings with an aeration disc, the shaft body is stable and fixed, reducing the requirements for the installation environment.
It realizes the fixed shaft body under low installation conditions, is suitable for use in flexible bag bodies, simplifies the installation process, improves operating stability, and reduces the requirements for rigid support containers.
Smart Images

Figure CN222918483U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of biological stirring, and particularly relates to a distributed bearing support structure for a bottom cantilever shaft. Background Art
[0002] Disposable bag-type bioreactors are widely used in the biochemical field. The magnetic stirrer for disposable bag-type bioreactors is a key device that matches the disposable bag-type bioreactor.
[0003] Most of the existing stirring mechanisms need to fix both ends of the stirring shaft, but this requires high installation conditions for the container. Generally, the existing disposable bottom multi-layer stirrers need to fix both ends of the stirring shaft to ensure the operation stability. This structure requires the top of the stirring shaft to be fixed above the stirring bag, the stirring shaft needs to be relatively long, there are many parts in the stirring bag, and the precision requirements for the supporting container are also relatively high. Summary of the Utility Model
[0004] In order to solve the above problems, the utility model provides the following solution:
[0005] A distributed bearing support structure for a bottom cantilever shaft, comprising
[0006] A shaft part, having
[0007] A mounting seat, the middle part of the welding disc is concave to form a mounting cavity, the mounting cavity is used to place one end of the shaft body, and the bottom of the mounting cavity is used to set a first bearing.
[0008] A shaft body, one end of which located in the mounting cavity has a reaction component and is sleeved with the first bearing, the shaft body is also sleeved with a second bearing, the second bearing is located outside the mounting cavity, and the second bearing can be abutted and limited by the inner ring limiting convex part of the inner ring surface of the aeration disc.
[0009] In some embodiments, one end of the shaft body is a shaft sleeve, and both ends of the shaft sleeve respectively have a first concave part and a second concave part. The first concave part is used to sleeve the first bearing, and the second concave part is used to sleeve the second bearing.
[0010] In some embodiments, there is a limiting convex part between the first concave part and the second concave part, which is used to limit the first bearing and the second bearing from approaching.
[0011] In some embodiments, the welding disc further has a connecting clip, the end of the connecting clip has an outwardly expanding elastic part, and after the outwardly expanding elastic part passes through the fixing hole of the aeration disc, the aeration disc is locked on the welding disc, and at this time, the inner ring limiting convex part axially locks the second bearing in the second concave part.
[0012] In some ways, when the outwardly expanding elastic member locks the aeration disc, the bushing is locked between the second bearing and the first bearing.
[0013] In some ways, the inner ring surface of the aeration disc has an inner ring limiting convex portion, and the inner ring limiting convex portion abuts against the upper end of the second bearing.
[0014] In some ways, the other end of the bushing is used to arrange a rotating shaft.
[0015] In some ways, one end of the shaft portion away from the bushing is not fixed.
[0016] In some ways, the outer edge of the welding disc is used to connect the opening portion of the flexible bag.
[0017] In some ways, the responsive component is a magnet.
[0018] The present disclosure has low requirements for installation conditions, can fix the shaft body only at one end, and is more suitable for use with flexible bag bodies. Two layers of blades can be installed, which is suitable for applications such as cell culture and bacterial fermentation. The stirring shaft fixed at one end has a relatively short shaft length, which is beneficial to improving the operation stability; since the fixing structure is all on one side, the product packaging and transportation are relatively simple; the requirements for a rigid support container are relatively low, and an upper support structure does not need to be provided. Description of the Drawings
[0019] Figure 1 Is a three-dimensional view of the installed state of the bottom cantilever shaft distributed bearing support structure;
[0020] Figure 2 Is a cross-sectional view of the installed state of the bottom cantilever shaft distributed bearing support structure;
[0021] Figure 3 、 4 Is an exploded view of the shaft;
[0022] Figure 5 Is a three-dimensional view of the combined state of the shaft;
[0023] Figure 6 Is a cross-sectional view of the aeration disc;
[0024] Figure 7 Is a connection state diagram of the bushing and the shaft body;
[0025] Figures 8 - 9 Is an assembly state diagram of the stirrer;
[0026] Figure 10 Is a diagram of the flow direction of bubbles and liquid after the aeration disc discharges gas.
[0027] In the figure:
[0028] 100 Shaft portion, 110 Shaft body, 120 Mounting seat, 121 Welding pad, 122 Reaction component, 123 Second bearing, 124 First bearing, 125 Connecting clip, 126 Outer expansion elastic member, 200 Aeration disk, 210 First annular inner cavity, 211 First aeration holes, 212 First air port, 220 Second annular inner cavity, 221 Second aeration holes, 222 Second air port, 310 Driving component, 320 Flexible bag. Detailed implementation mode
[0029] The following further describes the present utility model in conjunction with the accompanying drawings.
[0030] The bottom cantilever shaft distributed bearing support structure, which is also the shaft portion of the bioreactor in some cases, such as Figure 1 shown in, includes
[0031] Shaft portion 100, having
[0032] Mounting seat 120, the middle of its welding pad 121 is concaved to form a mounting cavity, the mounting cavity is used to place one end of the shaft body 110, and the bottom of the mounting cavity is used to set the first bearing 124,
[0033] Shaft body 110, one end of which located in the mounting cavity has a reaction component 122 and the end of this end is sleeved with the first bearing 124, the shaft body 110 is also sleeved with a second bearing 123, the second bearing 123 is located outside the mounting cavity, and the second bearing 123 is pressed and locked by the aeration disk 200; and
[0034] Aeration disk 200, which is a ring structure, its inner ring surface is used to abut against the second bearing 123, the aeration disk 200 has: mutually independent first annular inner cavity 210 and second annular inner cavity 220, the outer side wall of the first annular inner cavity 210 has a number of first aeration holes 211, the outer side wall of the second annular inner cavity 220 has a number of second aeration holes 221, the first annular inner cavity 210 has a first air port 212, and the second annular inner cavity 220 has a second air port 222. The aeration disk 200 also has a fixing hole penetrating the disk body for passing through the connecting clip 125.
[0035] Such as Figure 2As shown, one end of the shaft body 110 is a shaft sleeve. Both ends of the shaft sleeve respectively have a first concave portion and a second concave portion. The first concave portion is used for sleeving a first bearing 124, and the second concave portion is used for sleeving a second bearing 123. Moreover, there is a limiting convex portion between the first concave portion and the second concave portion, which is used to limit the first bearing 124 and the second bearing 123 from approaching. That is, by pressing the first bearing 124 and the second bearing 123 against the limiting convex portion, the positioning of the first bearing 124 and the second bearing 123 is realized, and at the same time, the positioning of the shaft sleeve is also realized. By arranging the first bearing 124 and the second bearing 123 for positioning at one end, it is possible to achieve fixation only by limiting at one end of the shaft body, so that the shaft portion can maintain its working state well without fixing the other end of the shaft portion 100, reducing the requirements for the installation environment.
[0036] As Figure 7 shown, the shaft body 110 and the shaft sleeve can be detachably connected. For example, a sleeve opening is provided at the end of the shaft sleeve, and then a fixing hole is opened on the side wall. A fixing hole is also provided on the side wall of the connecting end of the shaft body 110. The connecting end of the shaft body 110 is inserted into the sleeve opening of the shaft sleeve, and the fixing holes of the two are aligned. Finally, a locking pin 127 penetrates the fixing holes of the two to realize the limiting and locking of the two.
[0037] As Figure 3 、 4 shown, the inner ring surface of the aeration disc 200 has an inner ring limiting convex portion, and the inner ring limiting convex portion abuts against the upper end of the second bearing 123. The specific abutting manner between the limiting portion and the bearing is not particularly limited as long as the normal rotation of the bearing can be maintained.
[0038] As Figures 1 - 3 shown, the welding disc 121 further has a connecting clip 125. The end of the connecting clip 125 has an outwardly expanding elastic member 126. After the outwardly expanding elastic member 126 passes through the fixing hole of the aeration disc 200, the aeration disc 200 is locked to the welding disc 121, and at this time, the inner ring limiting convex portion axially locks the second bearing 123 to the second concave portion, that is, prevents the second bearing 123 from moving along the shaft body.
[0039] As Figure 2 、 4 shown, when the outwardly expanding elastic member 126 locks the aeration disc 200, the shaft sleeve is locked between the second bearing 123 and the first bearing 124.
[0040] As Figure 5 shown, the other end of the shaft sleeve away from the moving component 122 is used for arranging a rotating shaft.
[0041] In practical applications, the outer edge of the welding pad 121 is used to connect to the installation opening of the flexible bag 320 and can also be combined with other containers, without strict limitations in particular. The responsive component 122 is a magnet and can be rotated by the driving component 310, thereby driving the rotation of the shaft portion 100 to perform the stirring operation.
[0042] As Figure 10 shown in the figure, the air vent holes are used to introduce clean air to provide oxygen for the cells in the stirring bag. At the same time, two pore diameters of the air vent holes are set to facilitate improving the uniformity of dissolved oxygen in the liquid at various places in the stirring bag. (The smaller and denser the bubbles are, the larger the relative contact area with the liquid is, which can increase the oxygen dissolution rate. The floating rates of bubbles of different sizes are different. By setting different pore diameters, the large difference in bubble density at various places in the stirring bag can be avoided.) The inner diameter of the first air vent hole 211 is smaller than that of the second air vent hole 221; the chamber volume of the first annular inner cavity 210 is larger than that of the second annular inner cavity 220. The aeration disc 200 includes a first flap 201 and a second flap 202 that are buckled with each other. Among them, the first air port 212 that is the same as the first annular inner cavity 210 passes through the second annular inner cavity 220 through a pipe body, mainly to realize the ventilation of the first air port 212 and the second air port 222 on the premise of keeping the first annular inner cavity 210 and the second annular inner cavity 220 independent of each other.
[0043] As Figure 2 、 3 shown in the figure, two adjacent fixed fulcrums are arranged at one end of the cantilever shaft. The first fulcrum is close to the shaft end, and the rest is the second fulcrum. The fulcrum is a ceramic deep groove ball bearing. The other end of the shaft is in a free state. The distance from the second fulcrum to the free shaft end is the cantilever length, generally 3 to 7 times the fulcrum spacing. The axial force and radial force borne by the cantilever are jointly borne by the bearings serving as the fulcrums. The magnetic drive component is located in the middle of the two fulcrums. Compared with setting the drive component at the shaft end, it has better stability, and the tensile force borne by the magnetic drive component can offset part of the axial force borne by the fulcrum bearing, improving the durability of the bearing.
[0044] Those skilled in the art can clearly understand that various modifications can be made to the above embodiments without departing from the general spirit and concept of the present invention. All of them fall within the protection scope of the present invention. The protection scope of the present invention is subject to the claims attached to the present invention.
Claims
1. The bottom cantilever shaft distributed bearing support structure is characterized by: include The shaft portion (100) has The mounting seat (120) has a welding plate (121) whose middle part is concave to form a mounting cavity, the mounting cavity is used to place one end of the shaft body (110), and the bottom of the mounting cavity is used to set a first bearing (124). A shaft body (110) is provided with a response component (122) at one end thereof located in the installation cavity and the end is sleeved with a first bearing (124). The shaft body (110) is also sleeved with a second bearing (123). The second bearing (123) is located outside the installation cavity and can be abutted and limited by an inner ring limiting protrusion on the inner ring surface of the aeration disk (200).
2. The bottom cantilever shaft distributed bearing support structure according to claim 1, characterized in that: One end of the shaft body (110) is a shaft sleeve, and both ends of the shaft sleeve respectively have a first inner recess and a second inner recess, the first inner recess is used to sleeve a first bearing (124), and the second inner recess is used to sleeve a second bearing (123).
3. The bottom cantilever shaft distributed bearing support structure according to claim 2, characterized in that: A limiting convex portion is provided between the first inner concave portion and the second inner concave portion, and is used to limit the first bearing (124) and the second bearing (123) from approaching each other.
4. The bottom cantilever shaft distributed bearing support structure according to claim 3, characterized in that: The welding disc (121) further comprises a connecting clamp (125), and an end of the connecting clamp (125) comprises an outwardly expanding elastic member (126). After the outwardly expanding elastic member (126) passes through the fixing hole of the aeration disc (200), the aeration disc (200) is locked on the welding disc (121), and at this time, the inner ring limiting protrusion axially locks the second bearing (123) on the second inner recess.
5. The bottom cantilever shaft distributed bearing support structure according to claim 4, characterized in that: When the outwardly expanding elastic member (126) locks the aeration plate (200), the shaft sleeve is locked between the second bearing (123) and the first bearing (124).
6. The bottom cantilever shaft distributed bearing support structure according to claim 1, characterized in that: The inner ring surface of the aeration plate (200) has an inner ring limiting convex portion, and the inner ring limiting convex portion abuts against the upper end of the second bearing (123).
7. The bottom cantilever shaft distributed bearing support structure according to claim 2, characterized in that: The other end of the sleeve is used for arranging the rotating shaft.
8. The bottom cantilever shaft distributed bearing support structure according to claim 7, characterized in that: One end of the shaft portion (100) away from the shaft sleeve is not fixed.
9. The bottom cantilever shaft distributed bearing support structure according to claim 1, characterized in that: The outer edge of the welding plate (121) is used to connect the opening of the flexible bag.
10. The bottom cantilever shaft distributed bearing support structure according to claim 1, characterized in that: The responding component (122) is a magnet.