Quantitative split charging equipment for technetium-labeled medicine
By designing a technetium-labeled drug quantitative dispensing device containing a stirring barrel, mobile assembly and servo motor, the problem of volume consistency in existing equipment in multi-container quantitative dispensing is solved, and efficient and accurate dispensing of the drug liquid is achieved.
Patent Information
- Application Number
- CN202421758912.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-24
- Publication Date
- 2025-05-30
- Estimated Expiration
- 2034-07-24
AI Technical Summary
The existing technetium labeled drug dosing equipment has limitations in realizing the quantitative aggregation of multiple containers, and it is impossible to ensure that the amount of dispensing in each container is consistent.
A quantitative dispensing equipment for technetium-labeled drugs is designed, adopting a structure including a stirring barrel, feed tube, liquid dispensing tank, liquid dispensing tube, hose, hollow block, liquid inlet tube, discharge tube, injection cylinder and stirring mechanism. The cylinder is driven by a DC motor to drive the rotation of the cylinder, stirring sheet and scraper to rotate, and combine the synergy between the mobile components and the servo motor to achieve uniform stirring and quantitative extraction of the drug liquid.
It realizes uniform quantitative dispensing of multiple containers, ensures the consistent amount of liquid in each container, improves the efficiency and accuracy of dispensing, and meets the strict standards and regulatory requirements of the pharmaceutical industry.
Smart Images

Figure CN222922887U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of radioactive reagent sub-packaging, in particular to a quantitative sub-packaging device for technetium-labeled drugs. Background Technique
[0002] Technetium-labeled drugs are a class of drugs labeled with technetium isotopes and are used in nuclear medicine imaging diagnosis. By labeling technetium into the molecular structure, these drugs can track the distribution and metabolism of molecules in the human body, such as the functional status of bones, muscles, and organs. Technetium-labeled drugs are widely used in single-photon emission computed tomography to help doctors diagnose and evaluate various diseases. Their application depends on the short half-life and good biodistribution characteristics of technetium, enabling nuclear medicine imaging to provide high-sensitivity and high-resolution images and providing important support for clinical diagnosis.
[0003] However, the quantitative sub-packaging device for technetium-labeled drugs is a device specifically designed for accurately sub-packaging technetium-labeled drugs. Operators control the device through the user interface to ensure that the drugs are safely sub-packaged into the target container or preparation according to the predetermined dose, which can ensure the accuracy and reliability of the sub-packaging process, thus supporting accurate medical imaging diagnosis and research, aiming to improve the sub-packaging efficiency, ensure the safety of operators, and comply with strict pharmaceutical industry standards and regulatory requirements.
[0004] In the existing quantitative sub-packaging devices for technetium-labeled drugs, the pneumatic method is combined with a simple mechanical device to sub-package the reagent. Although the pneumatic method can avoid the problem of electronic device failure to a certain extent, it has limitations in realizing the quantitative sub-packaging of multiple containers and cannot ensure that the sub-packaging amount in each container is consistent. Content of the Utility Model
[0005] In order to make up for the above deficiencies, the utility model provides a quantitative sub-packaging device for technetium-labeled drugs, aiming to improve the limitation in realizing the quantitative sub-packaging of multiple containers in the prior art and the problem that the sub-packaging amount in each container cannot be ensured to be consistent.
[0006] To achieve the above object, the utility model adopts the following technical solutions: A quantitative dispensing device for technetium-labeled drugs, including a base, a support plate is fixedly connected to the top of the base, a stirring barrel is fixedly connected to the top of the support plate, a feed pipe is communicated with the top right side of the stirring barrel, a drain pipe is communicated with the bottom front of the outer wall of the stirring barrel, a valve is arranged on the outer wall of the drain pipe, the front end of the drain pipe is communicated with a liquid separation box, a plurality of liquid separation pipes are communicated with the front end of the liquid separation box, a hose is communicated with the front end of the liquid separation pipe, a hollow block is fixedly connected to the front of the support plate, a liquid inlet pipe is fixedly connected to the front of the hollow block, a first groove cylinder is fixedly connected to the rear side of the inner wall of the liquid inlet pipe, a discharge pipe is fixedly connected to the top of the hollow block, a second groove cylinder is fixedly connected to the bottom of the inner wall of the discharge pipe, a first baffle is arranged in the middle of the inner walls of the liquid inlet pipe and the discharge pipe, an injection cylinder is communicated with the top of the hollow block, a rubber cylinder is slidably connected to the inner wall of the injection cylinder, a moving component is arranged at the top of the rubber cylinder, and a stirring mechanism is arranged at the top of the stirring barrel, and the stirring mechanism is used to mix and stir the liquid medicine evenly.
[0007] As a further description of the above technical solution:
[0008] The stirring mechanism includes a DC motor, the DC motor is fixedly connected to the middle of the top of the stirring barrel, the output end of the DC motor penetrates through the stirring barrel and is fixedly connected to a cylinder, rotating plates are fixedly connected to the left and right sides of the top of the outer wall of the cylinder, a scraper is fixedly connected to the outside of the rotating plate, a plurality of stirring blades are fixedly connected to the middle of the outside of the cylinder, and a bottom scraper is fixedly connected to the bottom of the outer wall of the cylinder.
[0009] As a further description of the above technical solution:
[0010] The moving component includes a moving plate, the moving plate is fixedly connected to the tops of the plurality of rubber cylinders, a rack is fixedly connected to the right side of the moving plate, a servo motor is fixedly connected to the top right side of the support plate, a gear is fixedly connected to the output end of the servo motor, and the gear is meshed with the rack.
[0011] As a further description of the above technical solution:
[0012] A clamping plate is fixedly connected to the bottom front of the support plate, a collecting pipe is arranged at the front of the clamping plate, and a ring is fixedly connected to the outside of the collecting pipe.
[0013] As a further description of the above technical solution:
[0014] An outer frame is slidably connected to the outer wall of the second groove cylinder, the outer frame is engaged with the collecting pipe, an observation window is opened on the front outer wall of the stirring barrel, and an outer frame is fixedly connected to the outside of the observation window.
[0015] As a further description of the above technical solution:
[0016] A thermometer is fixedly connected to the right side of the outer wall of the stirring barrel, and a housing is fixedly connected to the outside of the thermometer.
[0017] As a further description of the above technical solution:
[0018] A controller is fixedly connected to the bottom right side of the support plate, and the controller is electrically connected to the servo motor and the DC motor respectively.
[0019] As a further description of the above technical solution:
[0020] A protective shell is fixedly connected to the outside of the controller, and a protective cover is rotatably connected to the outside of the protective shell.
[0021] The utility model has the following beneficial effects:
[0022] 1. In the utility model, the liquid medicine can be added to the stirring barrel through the feed pipe. Open the valve to make the liquid medicine flow into the liquid distribution box, pass through the liquid distribution pipe, hose to the liquid inlet pipe. The moving component drives the rubber cylinder to the top of the injection cylinder, generating suction to move the first baffle upward but blocked by the discharge pipe. The liquid medicine enters the injection cylinder through the hollow block. After pumping enough liquid medicine, the rubber cylinder moves downward to squeeze the liquid medicine, and the first baffle in the discharge pipe moves downward and is blocked by the second groove cylinder, and the liquid medicine flows out from the second groove cylinder, so that the liquid medicine can be evenly and quantitatively extracted.
[0023] 2. In the utility model, by starting the DC motor, the cylinder is driven to rotate, and then the rotating plate, stirring blades and bottom scraper are driven to rotate. The scraper rotates with the rotating plate, and the liquid medicine in the stirring barrel can be evenly stirred and mixed and then sub-packed. Description of the Drawings
[0024] Figure 1 It is the front view of the quantitative sub-packaging equipment for technetium-labeled drugs proposed by the utility model;
[0025] Figure 2 It is the three-dimensional view of the quantitative sub-packaging equipment for technetium-labeled drugs proposed by the utility model;
[0026] Figure 3 It is the cross-sectional view of the stirring barrel of the quantitative sub-packaging equipment for technetium-labeled drugs proposed by the utility model;
[0027] Figure 4 It is the cross-sectional view of the hollow block of the quantitative sub-packaging equipment for technetium-labeled drugs proposed by the utility model.
[0028] Legend Explanation:
[0029] 1. Base; 2. Stirring mechanism; 201. DC motor; 202. Cylinder; 203. Rotating plate; 204. Scraper; 205. Stirring blade; 206. Bottom scraper; 3. Support plate; 4. Stirring barrel; 5. Drain pipe; 6. Valve; 7. Liquid separation box; 8. Liquid separation pipe; 9. Hose; 10. Hollow block; 11. Liquid inlet pipe; 12. First groove cylinder; 13. First baffle; 14. Discharge pipe; 15. Second groove cylinder; 16. Injection cylinder; 17. Rubber cylinder; 18. Moving plate; 19. Rack; 20. Gear; 21. Servo motor; 22. Collection pipe; 23. Clamping plate; 24. Ring; 25. Feed pipe; 26. Observation window; 27. Outer frame; 28. Thermometer; 29. Outer shell; 30. Controller; 31. Protective shell; 32. Protective cover. Detailed implementation manners
[0030] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
[0031] Referring to Figure 1 . Figure 3 And Figure 4 , an embodiment provided by the present invention: a quantitative dispensing device for technetium-labeled drugs, including a base 1, a support plate 3 is fixedly connected to the top end of the base 1, a stirring barrel 4 is fixedly connected to the top end of the support plate 3, a feed pipe 25 is communicated with the right side of the top end of the stirring barrel 4, a drain pipe 5 is communicated with the bottom of the front wall of the stirring barrel 4, a valve 6 is arranged on the outer wall of the drain pipe 5, the front end of the drain pipe 5 is communicated with a liquid separation box 7, a plurality of liquid separation pipes 8 are communicated with the front end of the liquid separation box 7, the front end of the liquid separation pipe 8 is communicated with a hose 9, a hollow block 10 is fixedly connected to the front end of the support plate 3, a liquid inlet pipe 11 is fixedly connected to the front end of the hollow block 10, a first groove cylinder 12 is fixedly connected to the rear side of the inner wall of the liquid inlet pipe 11, a discharge pipe 14 is fixedly connected to the top of the hollow block 10, a second groove cylinder 15 is fixedly connected to the bottom of the inner wall of the discharge pipe 14, a first baffle 13 is arranged in the middle of the inner walls of the liquid inlet pipe 11 and the discharge pipe 14, an injection cylinder 16 is communicated with the top end of the hollow block 10, a rubber cylinder 17 is slidably connected to the inner wall of the injection cylinder 16, a moving assembly is arranged at the top end of the rubber cylinder 17, a stirring mechanism 2 is arranged at the top end of the stirring barrel 4, and the stirring mechanism 2 is used for mixing and stirring the liquid medicine evenly;
[0032] Specifically, the liquid medicine to be sub-packaged can be added into the stirring barrel 4 through the feed pipe 25. By opening the valve 6, the liquid medicine in the stirring barrel 4 can flow into the liquid separation box 7, and through the liquid separation pipe 8, it flows through the hose 9 into the liquid inlet pipe 11. By driving the rubber cylinder 17 to move towards the top of the injection cylinder 16 through the moving component, suction can be generated, causing the first baffle 13 at the bottom to move towards the top, but it will be blocked by the discharge pipe 14, thus blocking the discharge pipe 14. At the same time, the first baffle 13 in the liquid inlet pipe 11 will move towards the first groove cylinder 12, but the groove above the first groove cylinder 12 will allow the liquid medicine to flow through and enter the injection cylinder 16 under the action of suction. When the required volume of liquid medicine is extracted, the rubber cylinder 17 is moved towards the bottom of the injection cylinder 16 through the moving component, and at this time, the liquid medicine in the injection cylinder 16 will be extruded. At this time, the liquid inlet pipe 11 will be squeezed by the liquid medicine and blocked. At the same time, the first baffle 13 in the discharge pipe 14 will move towards the bottom of the discharge pipe 14 and be blocked by the second groove cylinder 15, but the liquid medicine can flow out through the groove above the second groove cylinder 15.
[0033] Referring to Figure 1 , Figure 2 and Figure 3 , the stirring mechanism 2 includes a DC motor 201, and the DC motor 201 is fixedly connected to the middle of the top end of the stirring barrel 4. The output end of the DC motor 201 penetrates through the stirring barrel 4 and is fixedly connected with a cylinder 202. The left and right sides of the outer wall top end of the cylinder 202 are fixedly connected with rotating plates 203, the outer sides of the rotating plates 203 are fixedly connected with scraping plates 204, the middle of the outer side of the cylinder 202 is fixedly connected with a plurality of stirring blades 205, and the bottom of the outer wall of the cylinder 202 is fixedly connected with a bottom scraping plate 206;
[0034] Specifically, by starting the DC motor 201, the cylinder 202 can be driven to rotate. As the cylinder 202 rotates, the outer rotating plates 203, stirring blades 205 and bottom scraping plate 206 can be driven to rotate. At the same time, the scraping plate 204 will rotate with the rotating plate 203, and the liquid medicine in the stirring barrel 4 can be stirred and mixed to make the liquid medicine mix more evenly before being sub-packaged.
[0035] Referring to Figure 1 and Figure 2, the moving component includes a moving plate 18, the moving plate 18 is fixedly connected to the tops of a plurality of rubber cylinders 17, a rack 19 is fixedly connected to the right side of the moving plate 18, a servo motor 21 is fixedly connected to the top right of the support plate 3, an output end of the servo motor 21 is fixedly connected to a gear 20, and the gear 20 is meshed with the rack 19; a clamping plate 23 is fixedly connected to the bottom front of the support plate 3, a collection pipe 22 is arranged at the front of the clamping plate 23, and a circular ring 24 is fixedly connected to the outer side of the collection pipe 22; an outer frame 27 is slidably connected to the outer wall of the second groove cylinder 15, and the outer frame 27 is engaged with the collection pipe 22, an observation window 26 is opened at the front outer wall of the stirring barrel 4, and an outer frame 27 is fixedly connected to the outer side of the observation window 26; a thermometer 28 is fixedly connected to the right outer wall of the stirring barrel 4, and a housing 29 is fixedly connected to the outer side of the thermometer 28;
[0036] Specifically, starting the servo motor 21 can drive the gear 20 to rotate. The rotation of the gear 20 can drive the movement of the rack 19. The movement of the rack 19 can drive the movement of the moving plate 18. The movement of the moving plate 18 can drive the movement of the rubber cylinders 17 at the bottom. The clamping plate 23 can limit the position of the collection pipe 22. The circular ring 24 can snap the collection pipe 22 above the clamping plate 23. The internal situation of the stirring barrel 4 can be observed through the observation window 26. The internal situation of the stirring barrel 4 can be known through the thermometer 28.
[0037] Refer to Figure 1 , Figure 2 and Figure 3 , a controller 30 is fixedly connected to the bottom right of the support plate 3, and the controller 30 is electrically connected to the servo motor 21 and the DC motor 201 respectively; a protective shell 31 is fixedly connected to the outer side of the controller 30, and a protective cover 32 is rotatably connected to the outer side of the protective shell 31;
[0038] Specifically, the controller 30 can respectively control the start and operating power between the servo motor 21 and the DC motor 20. The protective shell 31 can prevent the controller 30 from being damaged due to collision. The protective cover 32 can prevent dust, liquid, etc. from entering the inside of the controller 30 and causing damage to the internal electronic components.
[0039] Working principle: Before using this device, first, through the feed pipe 25, the liquid medicine to be sub-packed can be accurately added into the stirring barrel 4. Subsequently, by operating the valve 6, the liquid medicine in the stirring barrel 4 can smoothly flow into the liquid separation box 7, and through the liquid separation pipe 8 and the hose 9, it finally leads to the liquid inlet pipe 11. With the precise control of the moving component, the rubber cylinder 17 is driven to move towards the top of the injection cylinder 16. During this process, suction is generated, causing the first baffle 13 at the bottom to attempt to move upwards, but it is blocked by the discharge pipe 14, thereby ensuring the blocked state of the discharge pipe 14. At the same time, the first baffle 13 in the liquid inlet pipe 11 moves towards the first groove cylinder 12 under the action of suction, but the liquid medicine can flow smoothly through the groove above the first groove cylinder 12 and enter the injection cylinder 16 under the action of suction through the hollow block 10. When the required volume of liquid medicine is accurately extracted, the moving component operates again to make the rubber cylinder 17 move towards the bottom of the injection cylinder 16. At this time, the liquid medicine in the injection cylinder 16 is extruded under external pressure, and at the same time, the liquid inlet pipe 11 is squeezed and closed under the push of the liquid medicine to ensure that the liquid medicine does not flow back. At the same time, the first baffle 13 in the discharge pipe 14 moves towards the bottom of the discharge pipe 14 under external action and is blocked by the second groove cylinder 15, but the liquid medicine can still flow out smoothly through the groove above the second groove cylinder 15 to ensure the coherence and accuracy of the sub-packing process;
[0040] And through the stirring mechanism 2, during the operation process, by activating the DC motor 201, the cylinder 202 will start and rotate accordingly. The rotational movement of the cylinder 202 will trigger the synchronous rotation of the outer rotating plate 203, the stirring blades 205, and the bottom scraper 206. In addition, the scraper 204 will also move along with the rotation of the rotating plate 203. This series of rotational movements aims to stir and mix the liquid medicine in the stirring barrel 4 to ensure that the liquid medicine reaches a more uniform mixing state before sub-packing operation. The model of the servo motor 21 is MDME752GIH, and the model of the DC motor 201 is 57BL-1010H1-LS-B.
[0041] Finally, it should be noted that the above are only the preferred embodiments of the present utility model and are not used to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included in the protection scope of the present utility model.
Claims
1. A quantitative packaging device for technetium-labeled drugs, comprising a base (1), characterized in that: The top of the base (1) is fixedly connected to a support plate (3), the top of the support plate (3) is fixedly connected to a stirring barrel (4), the top right side of the stirring barrel (4) is connected to a feed pipe (25), the bottom of the front end of the outer wall of the stirring barrel (4) is connected to a drain pipe (5), the outer wall of the drain pipe (5) is provided with a valve (6), the front end of the drain pipe (5) is connected to a liquid separation box (7), the front end of the liquid separation box (7) is connected to a plurality of liquid separation pipes (8), the front end of the liquid separation pipe (8) is connected to a hose (9), the front end of the support plate (3) is fixedly connected to a hollow block (10), the front end of the hollow block (10) is fixedly connected to a liquid inlet pipe (11), the liquid inlet pipe ( A first groove cylinder (12) is fixedly connected to the rear side of the inner wall of the hollow block (11), a discharge pipe (14) is fixedly connected to the top of the hollow block (10), a second groove cylinder (15) is fixedly connected to the bottom of the inner wall of the discharge pipe (14), a first baffle (13) is provided in the middle of the inner wall of the liquid inlet pipe (11) and the discharge pipe (14), the top of the hollow block (10) is connected to an injection cylinder (16), the inner wall of the injection cylinder (16) is slidably connected to a rubber cylinder (17), a moving component is provided at the top of the rubber cylinder (17), and a stirring mechanism (2) is provided at the top of the stirring barrel (4), and the stirring mechanism (2) is used to mix and stir the liquid medicine evenly.
2. The quantitative packaging equipment for technetium-labeled drugs according to claim 1, characterized in that: The stirring mechanism (2) comprises a DC motor (201), the DC motor (201) being fixedly connected to the middle of the top end of the stirring barrel (4), the output end of the DC motor (201) passing through the stirring barrel (4) and being fixedly connected to a cylinder (202), the left and right sides of the top end of the outer wall of the cylinder (202) being fixedly connected to rotating plates (203), the outer side of the rotating plate (203) being fixedly connected to a scraper (204), the middle of the outer side of the cylinder (202) being fixedly connected to a plurality of stirring blades (205), and the bottom of the outer wall of the cylinder (202) being fixedly connected to a bottom scraper (206).
3. The quantitative packaging equipment for technetium-labeled drugs according to claim 1, characterized in that: The moving assembly comprises a moving plate (18), the moving plate (18) being fixedly connected to the top ends of the plurality of rubber cylinders (17), a rack (19) being fixedly connected to the right side of the moving plate (18), a servo motor (21) being fixedly connected to the top right side of the support plate (3), a gear (20) being fixedly connected to the output end of the servo motor (21), and the gear (20) being meshingly connected to the rack (19).
4. The quantitative packaging equipment for technetium-labeled drugs according to claim 1, characterized in that: A clamping plate (23) is fixedly connected to the bottom of the front end of the support plate (3), a collecting tube (22) is provided at the front end of the clamping plate (23), and a circular ring (24) is fixedly connected to the outside of the collecting tube (22).
5. The quantitative packaging equipment for technetium-labeled drugs according to claim 4, characterized in that: An outer frame (27) is slidably connected to the outer wall of the second groove cylinder (15), and the outer frame (27) is engaged with the collecting tube (22). An observation window (26) is provided at the front end of the outer wall of the mixing barrel (4), and the outer side of the observation window (26) is fixedly connected to the outer frame (27).
6. The quantitative packaging equipment for technetium-labeled drugs according to claim 1, characterized in that: A thermometer (28) is fixedly connected to the right side of the outer wall of the mixing barrel (4), and a housing (29) is fixedly connected to the outer side of the thermometer (28).
7. The quantitative packaging equipment for technetium-labeled drugs according to claim 2, characterized in that: A controller (30) is fixedly connected to the bottom right side of the support plate (3), and the controller (30) is electrically connected to the servo motor (21) and the DC motor (201) respectively.
8. The quantitative packaging equipment for technetium-labeled drugs according to claim 7, characterized in that: The outer side of the controller (30) is fixedly connected to a protective shell (31), and the outer side of the protective shell (31) is rotatably connected to a protective cover (32).