Electrochemiluminescence analysis device based on Linux operating system and USB camera
Through the modular design based on Linux operating system and USB camera, the existing electrochemiluminescence analysis device has been solved, and the effects of high integration, low cost, simple operation and multi-sample detection are achieved.
Patent Information
- Application Number
- CN202421210317.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-29
- Publication Date
- 2025-06-10
- Estimated Expiration
- 2034-05-29
AI Technical Summary
The existing electrochemiluminescence analysis devices are huge in size, expensive, complex in operation, and low in system integration. They cannot meet the needs of different detection scenarios, and cannot control multiple signal acquisition devices for multi-sample detection at the same time.
An electrochemiluminescence analysis device based on Linux operating system and USB camera is designed. The electrochemiluminescence signal acquisition device and the human-computer interaction device are electrically connected through a modular design to realize the integrated integration of signal acquisition, processing, analysis and storage, and support the control and multi-sample detection of multiple signal acquisition devices.
It improves the integration and modularity of the analysis device, reduces costs, simplifies operations, enhances adaptability and scalability, can meet the needs of different detection scenarios, and realizes simultaneous detection of multiple samples.
Smart Images
Figure CN222965121U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of electrochemiluminescence analysis, in particular to an electrochemiluminescence analysis device based on the Linux operating system and a USB camera. Background Art
[0002] Due to its characteristics such as high sensitivity, low background signal, and easy control, electrochemiluminescence analysis technology has been widely used in the fields of biological detection, environmental monitoring, medical diagnosis, etc. It combines the advantages of electrochemical triggering and optical signal readout, and can achieve fast response and high-sensitivity detection. For an electrochemiluminescence analysis device, it generally consists of an electrochemiluminescence signal acquisition device and a human-computer interaction device.
[0003] Existing electrochemiluminescence analysis devices generally adopt a human-computer interaction solution using a desktop or laptop computer to perform system control and data transmission on the electrochemiluminescence signal acquisition device. In this method, the electrochemiluminescence signal acquisition device generally adopts a certain optical signal acquisition detector, such as a photomultiplier tube, a photodiode, a complementary metal oxide semiconductor (CMOS) camera, a charge-coupled device (CCD) camera, etc.
[0004] The optical signal acquisition detector in the electrochemiluminescence signal acquisition device is usually a fixed detector, and the detected optical signal needs to be transmitted to an external computer for data processing and storage, which is bulky and costly. At the same time, the human-computer interaction device cannot realize the coordinated and integrated operation of signal transmission, data processing, data storage, data output, etc. of the electrochemiluminescence signal acquisition device. In addition, existing electrochemiluminescence analysis devices are usually bulky, expensive, complex to operate, and have low system integration, and have certain limitations in application; the optical signal acquisition device therein cannot meet the requirements for detectors in different detection scenarios and does not have universality in different detection scenarios. In addition, the human-computer interaction device in the existing electrochemiluminescence analysis device cannot control multiple signal acquisition devices at the same time and cannot realize the simultaneous detection of multiple different samples. Summary of the Utility Model
[0005] To solve the above technical problems, the utility model proposes an electrochemiluminescence analysis device based on the Linux operating system and a USB camera, which is simple to operate, has a high integration degree of the detection system, high cost performance, strong adaptability, and can control multiple signal acquisition devices. The device can efficiently realize the acquisition, processing, analysis, and storage of electrochemiluminescence signals, and at the same time has good universality and adaptability to meet the requirements for the analysis device in different detection scenarios.
[0006] To achieve the above object, the technical solution adopted by the utility model is as follows:
[0007] An electrochemiluminescence analysis device based on the Linux operating system and a USB camera, comprising at least one electrochemiluminescence signal acquisition device and a human-computer interaction device; the electrochemiluminescence signal acquisition device includes a signal acquisition communication module, one or more camera acquisition modules, an electrochemistry excitation module, and a chip access module; the human-computer interaction device includes a human-computer interaction communication module, a camera control module, a signal processing module, an output display module, and a data storage module;
[0008] The electrochemiluminescence signal acquisition device and the human-computer interaction device are electrically connected; the signal acquisition communication module is electrically connected to the camera acquisition module; the signal acquisition communication module is electrically connected or not connected to the electrochemistry excitation module; the signal acquisition communication module is electrically connected or not connected to the chip access module; the electrochemistry excitation module is electrically connected to the chip access module;
[0009] The human-computer interaction communication module is electrically connected to the USB camera control module; the human-computer interaction communication module is electrically connected to the electrochemiluminescence signal processing module; the human-computer interaction communication module is electrically connected to the output display module; the human-computer interaction communication module is electrically connected or network-connected to the data storage module;
[0010] The signal acquisition communication module is electrically connected to the human-computer interaction communication module;
[0011] In the electrochemiluminescence signal acquisition device, the signal acquisition communication module is used to transmit electrochemiluminescence image signal data to the human-computer interaction communication module and receive the camera control signal generated by the USB camera control module and transmitted to the human-computer interaction communication module; the camera acquisition module is used to receive the camera control signal received by the signal acquisition communication module and capture electrochemiluminescence image signals; the electrochemistry excitation module is used to provide electrochemistry excitation to trigger an electrochemiluminescence reaction to generate optical signals; the chip access module is used to load and unload electrochemiluminescence chips or sensors;
[0012] In the human-computer interaction device, the human-computer interaction communication module is used to receive the camera control signal generated by the USB camera control module and transmit the camera control signal to the signal acquisition communication module, and receive the electrochemiluminescence image signal data transmitted by the signal acquisition communication module and transmit the image signal data to the electrochemiluminescence signal processing module; the USB camera control module is used to generate camera control signals; the electrochemiluminescence signal processing module is used to process the image signal data; the output display module is used to display the electrochemiluminescence image signal data and the data processed by the electrochemiluminescence signal processing module; the data storage module is used to store the electrochemiluminescence image signal data and the data processed by the electrochemiluminescence signal processing module.
[0013] Further, both the signal acquisition communication module and the human-computer interaction communication module perform data transmission through a USB data cable.
[0014] Further, the camera acquisition module consists of a USB camera based on the UVC protocol and a camera fixing bracket with a matching size.
[0015] Further, the USB camera based on the UVC protocol can be a USB camera of different models or from different suppliers.
[0016] Further, the electrochemical excitation module and the chip access module are coupled to each other using copper contacts.
[0017] Further, the chip access module can achieve automatic access by being electrically connected to the signal acquisition and communication module, or manual access by not being connected.
[0018] Further, the human-computer interaction device uses the Orange Pi 3 LTS based on the Linux operating system, and can implement functions such as USB camera control, signal data processing, output display, and data storage;
[0019] Further, the data storage function uses local storage or network storage to store the video data captured by the USB camera control module, the pictures obtained by processing the video by the electrochemiluminescence signal processing module, and the data analysis results on a local memory card or a network server; the data storage function can download the data stored on the network server to a local memory card or other storage devices through the Internet.
[0020] Advantageous Effects
[0021] Compared with the prior art, the present utility model has the following advantages:
[0022] 1. By electrically connecting the electrochemiluminescence signal acquisition device and the human-computer interaction device and performing a modular design on the device, the present utility model realizes the integrated integration of the acquisition, processing, analysis, and storage of electrochemiluminescence signals, improving the integration level and modularization level of the analysis device.
[0023] 2. Both the USB camera based on the UVC protocol and the camera fixing bracket used in the camera acquisition module are replaceable, so the analysis device of the present utility model has good adaptability. Importantly, the analysis device of the present utility model can use USB cameras based on the UVC protocol of different models or from different suppliers, so it is easy to optimize the USB camera suitable for different application scenarios.
[0024] 3. The human-computer interaction device and the electrochemiluminescence signal acquisition device are electrically connected. The human-computer interaction device can connect and control at least one electrochemiluminescence signal acquisition device, and the electrochemiluminescence signal acquisition device can connect at least one camera acquisition module. Therefore, the analysis device of the present utility model has strong scalability.
[0025] 4. The output display module outputs and displays the video preview result and the data analysis result on the display screen, providing an intuitive user interaction experience.
[0026] 5. The data storage module uses local storage or network storage to ensure the security and accessibility of the experimental data.
[0027] 6. By adopting a camera component and a technical solution with high cost performance, the utility model reduces the cost of the analysis device while ensuring the analysis performance. Description of the Drawings
[0028] Figure 1 is the structural block diagram of the electrochemistry analysis device of the utility model based on the Linux operating system and the USB camera.
[0029] Figure 2 is the structural block diagram of the connection between three electrochemiluminescence signal acquisition devices and the human-computer interaction device in the utility model.
[0030] Figure 3 is the structural block diagram of the connection between the electrochemiluminescence signal acquisition device and three USB cameras in the utility model.
[0031] Figure 4 is the three-dimensional structural schematic diagram of the specific embodiment in the utility model;
[0032] Figure 5 is the right-side structural schematic diagram of the specific embodiment in the utility model;
[0033] Figure 6 is the left-side structural schematic diagram of the specific embodiment in the utility model;
[0034] Figure 7 is the structural schematic diagram of the cooperation between the spherical groove and the ball head in the specific embodiment in the utility model;
[0035] Explanation of the Reference Numerals in the Drawings:
[0036] 1 - Electrochemiluminescence signal acquisition device, 11 - Signal acquisition communication module, 12 - Camera acquisition module, 13 - Electrochemical excitation module, 14 - Chip access module;
[0037] 2 - Human-computer interaction device, 21 - Human-computer interaction communication module, 22 - USB camera control module, 23 - Electrochemiluminescence signal processing module, 24 - Output display module, 25 - Data storage module;
[0038] A1 - Electrochemiluminescence signal acquisition device 1, A11 - Signal acquisition communication module, A12 - Camera acquisition module, A13 - Electrochemical excitation module, A14 - Chip access module;
[0039] B1 - Electrochemiluminescence signal acquisition device 2, B11 - Signal acquisition and communication module, B12 - Camera acquisition module, B13 - Electrochemical excitation module, B14 - Chip access module;
[0040] C1 - Electrochemiluminescence signal acquisition device 3, C11 - Signal acquisition and communication module, C12 - Camera acquisition module, C13 - Electrochemical excitation module, C14 - Chip access module;
[0041] 121 - USB Camera A, 122 - USB Camera B, 123 - USB Camera C;
[0042] 201 - Box body, 13 - Electrochemical excitation module, 14 - Chip access module, 202 - Intermediate plate, 203 - USB camera, 204 - Rear side plate, 205 - Orange Pi, 206 - Sliding drawer, 207 - Bottom plate, 208 - Bottom plate track, 209 - Right side plate, 210 - Exit, 211 - Spherical groove, 212 - Spring pin, 213 - Ball head, 214 - Rechargeable power source, 215 - Front side plate, 216 - Inclined mounting surface, 217 - Display screen, 218 - Camera fixing bracket, 219 - Mounting seat, 220 - Top plate, 221 - Handle, 222 - Left side plate. Detailed implementation
[0043] The following further describes a kind of electrochemiluminescence analysis device based on Linux operating system and USB camera of the present utility model in conjunction with the accompanying drawings and specific embodiments.
[0044] The present utility model discloses an electrochemiluminescence analysis device based on Linux operating system and USB camera, including at least one electrochemiluminescence signal acquisition device 1 and a human - machine interaction device 2 ( Figure 1 and Figure 2 ); the electrochemiluminescence signal acquisition device 1 includes a signal acquisition and communication module 11, one or more camera acquisition modules 12 ( Figure 3 ), an electrochemical excitation module 13, a chip access module 14; the human - machine interaction device 2 includes a human - machine interaction communication module 21, a camera control module 22, a signal processing module 23, an output display module 24, and a data storage module 25.
[0045] The electrochemiluminescence signal acquisition device 1 and the human - machine interaction device 2 are electrically connected; the signal acquisition and communication module 11 is electrically connected to the camera acquisition module 12; the signal acquisition and communication module 11 is electrically connected or not connected to the electrochemical excitation module 13; the signal acquisition and communication module 11 is electrically connected or not connected to the chip access module 14; the electrochemical excitation module 13 is electrically connected to the chip access module 14.
[0046] The human-computer interaction communication module 21 is electrically connected to the USB camera control module 22; the human-computer interaction communication module 21 is electrically connected to the electrochemiluminescence signal processing module 23; the human-computer interaction communication module 21 is electrically connected to the output display module 24; the human-computer interaction communication module 21 is electrically connected or network-connected to the data storage module 25.
[0047] The signal acquisition and communication module 11 is electrically connected to the human-computer interaction communication module 21.
[0048] In the electrochemiluminescence signal acquisition device 1, the signal acquisition and communication module 11 is used to transmit electrochemiluminescence image signal data to the human-computer interaction communication module 21 and receive the camera control signal generated by the USB camera control module 22 and transmitted to the human-computer interaction communication module 21; the camera acquisition module 12 is used to receive the camera control signal received by the signal acquisition and communication module 11 and capture electrochemiluminescence image signals; the electrochemiluminescence excitation module 13 is used to provide electrochemiluminescence excitation to trigger an electrochemiluminescence reaction to generate optical signals; the chip access module 14 is used to load and unload electrochemiluminescence chips or sensors.
[0049] In the human-computer interaction device 2, the human-computer interaction communication module 21 is used to receive the camera control signal generated by the USB camera control module 22 and transmit the camera control signal to the signal acquisition and communication module 11, and receive the electrochemiluminescence image signal data transmitted by the signal acquisition and communication module 11 and transmit the image signal data to the electrochemiluminescence signal processing module 23; the USB camera control module 22 is used to generate camera control signals; the electrochemiluminescence signal processing module 23 is used to process image signal data; the output display module 24 is used to display electrochemiluminescence image signal data and the data processed by the electrochemiluminescence signal processing module 23; the data storage module 25 is used to store electrochemiluminescence image signal data and the data processed by the electrochemiluminescence signal processing module 23.
[0050] Further, both the signal acquisition and communication module 11 and the human-computer interaction communication module 21 perform data transmission through a USB data cable.
[0051] Further, the camera acquisition module 12 consists of a USB camera based on the UVC protocol and a camera fixing bracket with a matching size.
[0052] Further, the UVC protocol camera can be a UVC camera of different models or from different suppliers.
[0053] Further, the electrochemiluminescence excitation module 13 and the chip access module 14 are coupled to each other using copper contacts, that is, connected by copper wires, with low resistance.
[0054] Further, the chip access module 14 can achieve automatic access by being electrically connected to the signal acquisition and communication module 11, or achieve manual access without connection.
[0055] Further, the human-computer interaction device 2 uses the Orange Pi 3 LTS based on the Linux operating system, and can implement functions such as USB camera control, signal data processing, output display, and data storage.
[0056] Further, the data storage function uses local storage or network storage to store the video data captured by the USB camera control module 22, the pictures obtained by processing the video by the electrochemiluminescence signal processing module 23, and the data analysis results on a local memory card or a network server; the data storage function can download the data stored on the network server to a local memory card or other storage devices through the Internet. Specific embodiments
[0058] As Figures 4 - 7 shown, it includes a box body 201, an electrochemistry excitation module 13, and a chip access module 14. The chip access module 14 is used to install an electrochemiluminescence chip. Both the electrochemistry excitation module 13 and the chip access module 14 adopt modules in the prior art. A middle plate 202 is provided in the box body 201 to divide the inner cavity of the box body 201 into upper and lower parts. The upper part is an electrical equipment installation room, and the lower part is an electrochemiluminescence reaction room. A USB camera 203 is provided in the middle of the middle plate 202, and the lens of the USB camera 203 passes downward through the middle plate 202. The electrochemistry excitation module 13 is installed on one side of the middle plate 202. On the rear side plate 204 of the box body 201 above the middle plate 202, an Orange Pi 205 installed with the Linux operating system is provided. A sliding drawer 206 is provided directly below the lens of the USB camera 203. A bottom plate track 208 for installing the sliding drawer 206 is provided on the bottom plate 207 of the box body 201. An outlet 210 corresponding to the sliding drawer 206 is provided on the right side plate 209 of the box body 201. Spherical grooves 211 are respectively provided on the right side plate 209 on both sides of the outlet 210. Spring pins 212 are respectively provided on both sides of the sliding drawer 206, and a ball head 213 adapted to the spherical groove 211 is provided at one end of the spring pin 212. When the sliding drawer 206 is pushed in place, the ball heads 213 on both sides of the sliding drawer 206 just snap into the spherical grooves 211 to play a limiting role. When the sliding drawer 206 needs to be pulled out, as long as a little force is used to pull the sliding drawer 206, after overcoming the resistance of the spring pin 212 to snap the ball head 213 into the spherical groove 211, the ball head 213 retracts, and the sliding drawer 206 can be pulled out. The chip access module 14 is installed in the sliding drawer 206. The Orange Pi 205 is electrically connected to the USB camera 203 and the electrochemistry excitation module 13, and the electrochemistry excitation module 13 is electrically connected to the chip access module 14.
[0059] An rechargeable power supply 214 is provided on the outer side of the rear side plate 204. The Orange Pi 205 is electrically connected to the rechargeable power supply 214. Preferably, the rechargeable power supply 214 includes a lithium battery to ensure that the analysis can continue even when the mains power fails.
[0060] At the top of the front side plate 215 of the box body 201, there is an inclined mounting surface 216. The inclined mounting surface 216 is equipped with a display screen 217. The display screen 217 serves as the output display module 24. The Orange Pi 205 is electrically connected to the display screen 217. The display screen 217 is an LCD display screen.
[0061] The USB camera 203 is installed inside the camera fixing bracket 218. The middle plate 202 is provided with a mounting seat 219 with a cuboid structure for mounting the camera fixing bracket 218. The camera fixing bracket 218 is adaptively made according to the specific model and size of the USB camera 203.
[0062] The top plate 220 of the box body 201 is provided with a handle 221, which can facilitate the carrying of this device.
[0063] A sealing strip is provided between the sliding drawer 206 and the right side plate 209, which is similar to the sealing strip structure of a refrigerator door. After the sliding drawer 206 is pushed in place, the sealing strip of the sliding drawer 206 contacts the surface of the right side plate 209 to achieve sealing.
[0064] Preferably, the USB camera 203 is a USB camera with a UVC protocol. The Orange Pi 205 uses an Orange Pi 3 LTS with 2GB of application memory. The Orange Pi 3 LTS is a 32-bit, 1.5GHz quad-core processor, with two USB interfaces. The operating system installs the Linux operating system and its USB interface driver, and the parameters of the USB camera can be controlled by writing programs through calling the USB interface driver of the Linux operating system.
[0065] On the inner sides of the front side plate 215, rear side plate 204, left side plate 222, right side plate 209, bottom plate 207 of the box body 201, and the bottom of the middle plate 202, there are all black material layers to improve a good dark environment and ensure the accuracy of the analysis. Preferably, polylactic acid (PLA) black material can be used to manufacture the front side plate 215, rear side plate 204, left side plate 222, right side plate 209, bottom plate 207 and middle plate 202 of the box body 201 through a 3D printing device.
[0066] The left side plate 222 and right side plate 209 of the box body 201 are both installed by bolts, which can facilitate the disassembly and assembly of the left side plate 222 and right side plate 209. After removing the left side plate 222 and right side plate 209, it is convenient to install the devices inside the box body 201.
[0067] The electrochemiluminescence reaction chamber is separated by an intermediate plate, and the electrochemiluminescence chip is loaded through a sliding drawer, which can effectively reduce the influence of the peripheral environment on the data analysis process. Moreover, by loading through a sliding drawer, there is no need to open the side plate of the box body, greatly reducing the dust entering the electrochemiluminescence reaction chamber, thus greatly reducing the dust pollution of the chip access module. The overall structure of the utility model is simple, compact, small in volume, convenient to carry, and low in cost.
[0068] The above is only the preferred embodiment of the utility model. It should be pointed out that for those skilled in the art, without departing from the structure of the utility model, several deformations and improvements can be made, which will not affect the implementation effect of the utility model and the practicability of the patent.
Claims
1. An electrochemiluminescence analysis device based on Linux operating system and USB camera, characterized in that: The invention comprises at least one electrochemiluminescent signal acquisition device (1) and a human-machine interaction device (2), wherein the electrochemiluminescent signal acquisition device (1) comprises a signal acquisition communication module (11), one or more camera acquisition modules (12), an electrochemical excitation module (13) and a chip input / output module (14); the human-machine interaction device (2) comprises a human-machine interaction communication module (21), a USB camera control module (22), an electrochemiluminescent signal processing module (23), an output display module (24) and a data storage module (25); and the electrochemiluminescent signal acquisition device (1) and the human-machine interaction device (2) are electrically connected.
2. The electrochemiluminescence analysis device based on Linux operating system and USB camera according to claim 1, characterized in that: The signal acquisition communication module (11) and the human-computer interaction communication module (21) are connected via a USB data cable.
3. The electrochemiluminescence analysis device based on Linux operating system and USB camera according to claim 1, characterized in that: A human-machine interaction device (2) can be connected to at least one electrochemiluminescent signal acquisition device (1), and an electrochemiluminescent signal acquisition device (1) can be connected to one or more camera acquisition modules (12).
4. The electrochemiluminescence analysis device based on Linux operating system and USB camera according to claim 1, characterized in that: The camera acquisition module (12) consists of a USB camera based on the UVC protocol and a camera fixing bracket with matching size.
5. The electrochemiluminescence analysis device based on Linux operating system and USB camera according to claim 1, characterized in that: The electrochemical excitation module (13) and the chip in-and-out module (14) are coupled to each other using copper contacts.
6. The electrochemiluminescence analysis device based on Linux operating system and USB camera according to claim 1, characterized in that: The output display module (24) is used to display the electrochemiluminescence image signal data and the data processed by the electrochemiluminescence signal processing module.
7. The electrochemiluminescence analysis device based on Linux operating system and USB camera according to claim 1, characterized in that: The data storage module (25) uses local storage or network storage to store the video data and the pictures and data analysis results obtained by electrochemical luminescence signal processing on a local memory card or a network server.
8. The electrochemiluminescence analysis device based on Linux operating system and USB camera according to claim 1, characterized in that: The electrochemiluminescence analysis device can be adapted to USB cameras of different models or different suppliers to meet the needs of different detection scenarios.