Medical flexible miniature cerebral cortex electrode implanted in body

Abstract

The utility model discloses a medical flexible miniature cerebral cortex electrode implanted in vivo. The medical flexible miniature cerebral cortex electrode comprises an electrode contact area, an electrode welding spot area and a connecting area for connecting the electrode contact area and the electrode welding spot area, the electrode contact area comprises a plurality of electrode contacts, the electrode welding spot area is provided with a plurality of electrode welding spots, the connecting area is provided with connecting wires, and the connecting wires are electrically connected with the electrode contacts and the electrode welding spots respectively; the electrode contact area comprises corner subareas, the flexible miniature cerebral cortex electrode further comprises at least one elastic structure, and the elastic structures are arranged in the corner subareas. According to the technical scheme, the elastic structure is arranged to adapt to micro movement of brain tissue, and on one hand, the stability of the flexible miniature cerebral cortex electrode for recording neuron activity signals and the effectiveness of electrical stimulation can be guaranteed; on the other hand, damage to brain tissue can be reduced, and inflammatory response is relieved.

Description

Technical Field

[0001] The utility model relates to the technical field of brain-computer interfaces, and particularly relates to a flexible micro-cortical electrode implanted in the body for medical use. Background Art

[0002] Brain-computer interface is an important technology that directly connects the brain with a computer or other external devices through a sensing terminal to extract, decode brain signals and finally convert them into command signals that can be used to control external devices without relying on traditional output channels. Among them, one of the key components of the brain-computer interface is information extraction, that is, reading the information in the biological brain. At present, there are mainly two main information extraction methods, namely non-invasive and invasive information extraction methods. The non-implanted method reads electroencephalogram (EEG) data through an EEG cap worn on the scalp; while the implanted method includes obtaining EEG data through implanted microelectrode arrays, deep brain electrodes, and semi-implanted electrocorticography (EcoG) electrodes, etc. Among these technologies, EcoG electrodes have been widely used in the field of brain-computer interfaces due to their high signal resolution, relatively long-term stability, and relatively less invasiveness.

[0003] Existing flexible electrodes cannot adapt to the micro-movement of brain tissue, affecting the stability of neuron activity signal recording and the effectiveness of electrical stimulation, and are prone to causing damage to brain tissue and triggering inflammatory reactions. Summary of the Utility Model

[0004] The utility model provides a flexible micro-cortical electrode implanted in the body for medical use to solve the problems that existing flexible electrodes cannot adapt to the micro-movement of brain tissue, affect the stability of neuron activity signal recording and the effectiveness of electrical stimulation, and are prone to causing damage to brain tissue and triggering inflammatory reactions.

[0005] According to the utility model, a flexible micro-cortical electrode implanted in the body for medical use includes an electrode contact area, an electrode solder area, and a connection area connecting the electrode contact area and the electrode solder area;

[0006] The electrode contact area includes a plurality of electrode contacts, the electrode solder area is provided with a plurality of electrode solders, the connection area is provided with connection traces, and the connection traces are electrically connected to the electrode contacts and the electrode solders respectively;

[0007] The electrode contact area includes a corner partition, and the flexible micro-cortical electrode further includes at least one elastic structure, and the elastic structure is arranged in the corner partition.

[0008] Optionally, the corner partitions include a first type of corner partition and a second type of corner partition. The first type of corner partition is located on a side of the electrode contact area away from the connection area, and the second type of corner partition is located on a side of the electrode contact area close to the connection area;

[0009] The first type of corner partition includes a first side and a second side. The first side and the second side are connected and the extension directions intersect. The second type of corner partition includes a third side, and the extension direction of the third side is parallel to the extension direction of the first side;

[0010] At least one of the elastic structures is provided on both the first side and the second side, and at least one of the elastic structures is provided on the third side.

[0011] Optionally, the first type of corner partition includes a first corner partition and a second corner partition, the second type of corner partition includes a third corner partition and a fourth corner partition, the first corner partition and the third corner partition are on the same side of the electrode contact area, and the second corner partition and the fourth corner partition are on the same side of the electrode contact area;

[0012] At least one of the elastic structures includes a first elastic structure provided on the first side of the first corner partition, a second elastic structure provided on the second side of the first corner partition, a third elastic structure provided on the first side of the second corner partition, a fourth elastic structure provided on the second side of the second corner partition, a fifth elastic structure provided on the third side of the third corner partition, and a sixth elastic structure provided on the third side of the fourth corner partition.

[0013] Optionally, the distance between the first elastic structure and the fifth elastic structure is the same as the distance between the third elastic structure and the sixth elastic structure.

[0014] Optionally, the flexible microcortical electrode further includes a flexible substrate;

[0015] The flexible substrate includes a contact substrate part located in the electrode contact area;

[0016] The elastic structure is connected to and integrally provided with the contact substrate part.

[0017] Optionally, the elastic structure includes N elastic parts, where N≥2 and N is an integer;

[0018] The N elastic parts are arranged along the thickness direction of the flexible microcortical electrode, and two adjacent elastic parts are connected;

[0019] The first elastic branch is used to contact the meninges, and the Nth elastic branch is connected to the contact substrate branch.

[0020] Optionally, the thickness of the elastic branch is the same as that of the contact substrate branch.

[0021] Optionally, the thickness of the elastic branch is 5μm - 100μm.

[0022] Optionally, in the same elastic structure, the widths of any two elastic branches are the same.

[0023] Optionally, the elastic expansion range of the elastic structure is between 1mm and 2mm.

[0024] By providing an elastic structure in the corner partition of the electrode contact area, the compliance of the flexible microcortical electrode is increased to adapt to the micro - movement of the brain tissue, thereby ensuring the stability of recording neuron activity signals and the effectiveness of electrical stimulation of the flexible microcortical electrode. In addition, the buffering effect of the elastic structure enables the flexible microcortical electrode to have a certain elastic deformation space when subjected to external forces, thus reducing damage to the brain tissue. Secondly, the setting of the elastic structure reduces the relative movement between the flexible microcortical electrode and the brain tissue, helps to reduce the inflammatory response, and enhances biocompatibility.

[0025] It should be understood that the content described in this part is not intended to identify the key or important features of the embodiments of the present invention, nor is it used to limit the scope of the present invention. Other features of the present invention will become easily understandable through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0027] Figure 1 is a schematic structural diagram of the first flexible microcortical electrode implanted in the body for medical use according to an embodiment of the present invention;

[0028] Figure 2 is a schematic structural diagram of the second flexible microcortical electrode implanted in the body for medical use according to an embodiment of the present invention;

[0029] Figure 3 is a schematic structural diagram of the third flexible microcortical electrode implanted in the body for medical use according to an embodiment of the present invention;

[0030] Figure 4 It is a schematic diagram of the fourth flexible micro-cortical electrode structure for in-vivo implantation in medicine according to an embodiment of the present invention;

[0031] Figure 5 It is a schematic diagram of the structure of an electrode contact area according to an embodiment of the present invention;

[0032] Figure 6 It is a schematic diagram of an elastic structure according to an embodiment of the present invention. Detailed implementation manners

[0033] In order to enable those skilled in the art to better understand the solution of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0034] It should be noted that the terms "first", "second", etc. in the specification and claims of the present invention and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that such data used may be interchanged under appropriate circumstances so that the embodiments of the present invention described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" any variations are intended to cover non-exclusive inclusions. For example, a process, method, system, product, or device that includes a series of steps or units does not necessarily have to be limited to those steps or units clearly listed, but may include other steps or units not clearly listed or inherent to these processes, methods, products, or devices.

[0035] Figure 1 It is a schematic diagram of a flexible micro-cortical electrode structure for in-vivo implantation in medicine according to an embodiment of the present invention; Figure 2 It is a schematic diagram of the second flexible micro-cortical electrode structure for in-vivo implantation in medicine according to an embodiment of the present invention; Figure 3 It is a schematic diagram of the third flexible micro-cortical electrode structure for in-vivo implantation in medicine according to an embodiment of the present invention; Figure 4 It is a schematic diagram of the fourth flexible micro-cortical electrode structure for in-vivo implantation in medicine according to an embodiment of the present invention. This embodiment can be implanted under the dura mater of the brain for a long time to stably collect neuron activity data. Such as Figure 1 , Figure 2 , Figure 3 and Figure 4As shown in the figure, the flexible microcortical electrode includes an electrode contact area 1, an electrode soldering area 2, and a connection area 3 connecting the electrode contact area 1 and the electrode soldering area 2. The electrode contact area 1 is provided with a plurality of electrode contacts 11, the electrode soldering area 2 is provided with a plurality of electrode solders 21, and the connection area 3 is provided with connection traces 31, and the connection traces 31 are electrically connected to the electrode contacts 11 and the electrode solders 21 respectively. The electrode contact area 1 includes a corner partition 4, and the flexible microcortical electrode further includes at least one elastic structure 5, and the elastic structure 5 is disposed in the corner partition 4.

[0036] Specifically, there are a plurality of uniformly distributed electrode contacts 11 on the electrode contact area 1, and the electrode contact area 1 contacts the brain tissue through the electrode contacts 11 to measure neuron activity signals. There are a plurality of uniformly distributed electrode solders 21 on the electrode soldering area 2, and the electrode solders 21 and the electrode contacts 11 are electrically connected through the connection traces 31 on the electrode connection area 3 to transmit the neuron activity signals obtained by the electrode contact area 1 to the electrode soldering area 2. The electrode soldering area 2 is soldered to a flexible printed circuit board (FPC) through the electrode solders 21 (not shown in the figure). The flexible printed circuit board receives the neuron activity signals and, as a signal transmission medium, transmits the neuron activity signals to the main board or the processor to process and analyze the neuron activity signals, so as to extract, decode and finally convert the brain signals into command signals that can be used to control external devices.

[0037] It can be understood that the four corners of the electrode contact area 1 are used as the corner partitions 4, and the elastic structure 5 is disposed on the corner partitions 4. The elastic structure 5 refers to a structure with elastic and stretchable characteristics, such as a spring. The flexible microcortical electrode is usually disposed under the dura mater. One end of the elastic structure 5 contacts the dura mater, and the other end adheres to the cerebral cortex with the electrode contact area 1. The elastic structure 5 can increase the compliance of the flexible microcortical electrode, so as to adapt to the slight movement of the brain tissue, reduce the electrode displacement caused by the movement of the brain tissue or the pressure change, and ensure the stability of the neuron activity signal recorded by the flexible microcortical electrode and the effectiveness of the electrical stimulation. In addition, the buffering effect of the elastic structure 5 enables the flexible microcortical electrode to have a certain elastic deformation space when subjected to an external force, rather than directly transmitting it to the brain tissue, thereby reducing the damage to the brain tissue. Further, the setting of the elastic structure 5 reduces the relative movement between the flexible microcortical electrode and the brain tissue, helps to reduce the inflammatory reaction, and enhances the biocompatibility. Among them, biocompatibility refers to the compatibility between the material and the organism, including the behavior, reaction and possible biological effects of the material in the organism.

[0038] It should be noted that the concept of "miniature" in the flexible microcortical electrode is mainly reflected in the size of the electrode contact 11. The contact size of the existing clinical cortical electrodes is above the millimeter level, while the diameter of the electrode contact 11 in this embodiment is between 10 μm and 1000 μm, that is, the electrode contact size is at the micron level. The flexible microcortical electrode in this application has micron-level electrode contacts. Such a small electrode size can not only improve the spatial resolution and obtain higher signal quality, but also reduce the damage to the surrounding tissues. In addition, the flexible microcortical electrode is suitable for clinical application scenarios that require high-precision brain activity monitoring, complex nerve function research, and high positioning accuracy.

[0039] It should be noted that each electrode contact 11 can be electrically connected to the electrode solder joint 12 through the connection trace 31 on the electrode connection area 3. Figure 1 Only some of the electrode contacts 11 are taken as an example for illustration through the connection trace 31 on the electrode connection area 3, rather than a limitation.

[0040] In the embodiment of the present utility model, by arranging an elastic structure in the corner partition of the electrode contact area, the compliance of the flexible microcortical electrode is increased to adapt to the micro-movement of the brain tissue, thereby ensuring the stability of the flexible microcortical electrode in recording neuron activity signals and the effectiveness of electrical stimulation. In addition, the buffering effect of the elastic structure enables the flexible microcortical electrode to have a certain elastic deformation space when subjected to an external force, thereby reducing the damage to the brain tissue. Secondly, the arrangement of the elastic structure reduces the relative movement between the flexible microcortical electrode and the brain tissue, helps to reduce the inflammatory reaction, and enhances the biocompatibility.

[0041] On the basis of the above embodiment, this embodiment further describes the setting position of the elastic structure. Figure 5 It is a schematic diagram of the structure of an electrode contact area provided according to an embodiment of the present utility model. As Figure 5 shown, the corner partition 4 includes a first type of corner partition 41 and a second type of corner partition 42. The first type of corner partition 41 is located on the side of the electrode contact area 1 far from the connection area 3, and the second type of corner partition 42 is located on the side of the electrode contact area 1 close to the connection area 3; the first type of corner partition 1 includes a first side 411 and a second side 412, the first side 411 and the second side 412 are connected and the extension directions intersect, and the second type of corner partition 42 includes a third side 423, and the extension direction of the third side 423 is parallel to the extension direction of the first side 411; at least one elastic structure 5 is provided on both the first side 411 and the second side 412, and at least one elastic structure 5 is provided on the third side 423.

[0042] Specifically, referring to Figure 5, the corner partitions 4 are divided into two categories. The first type of corner partition 41 is the corner partition 4 provided in the electrode contact area 1 away from the connection area 3, and the first type of corner partition 41 is located at the end of the electrode contact area 1. Since the first type of corner partition 41 is provided at the end of the electrode contact area 1, it has more exposed boundaries. For example, the first side 411 and the second side 412 in the first type of corner partition 41 are both exposed. Therefore, at least one elastic structure 5 is provided on the first side 411 and the second side 412 of each first type of corner partition 41. In this way, two elastic structures 5 are provided for each first type of corner partition 41. Since the second type of corner partition 42 is the corner partition connected to the connection area 3 and has a smaller exposed boundary. For example, the third side 423 in the second type of corner partition 42 is exposed. Therefore, at least one elastic structure 5 is provided on the third side 423 of each second type of corner partition 42. In this way, one elastic structure 5 is provided for each second type of corner partition 42. In this way, at least one elastic structure 5 is provided on each corner partition 4. The advantage of this setting is that it can provide a relatively uniform supporting force for the flexible microcortical electrode, help maintain the flatness of the electrode, further improve the stability of the flexible microcortical electrode, enable it to better adapt to the micro-movement of brain tissue while reducing damage to the surrounding brain tissue.

[0043] Based on the above embodiments, this embodiment further describes the setting of the elastic structure. As Figure 5 shown, the first type of corner partition 41 includes a first corner partition 4111 and a second corner partition 4112, the second type of corner partition 42 includes a third corner partition 4213 and a fourth corner partition 4214. The first corner partition 4111 and the third corner partition 4213 are on the same side of the electrode contact area, and the second corner partition 4112 and the fourth corner partition 4214 are on the same side of the electrode contact area; at least one elastic structure 5 includes a first elastic structure 51 provided on the first side 411 of the first corner partition 4111, a second elastic structure 52 provided on the second side 412 of the first corner partition 4111, a third elastic structure 53 provided on the first side 411 of the second corner partition 4112, a fourth elastic structure 54 provided on the second side 412 of the second corner partition 4112, a fifth elastic structure 55 provided on the third side 423 of the third corner partition 4213, and a sixth elastic structure 56 provided on the third side 423 of the fourth corner partition 4214.

[0044] Specifically, referring to Figure 5, taking four corner partitions 4 and six elastic structures 5 as an example for illustration. The first type of corner partition 41 includes a first corner partition 4111 and a second corner partition 4112. Among them, a first elastic structure 51 is provided on the first side 411 of the first corner partition 4111, and a second elastic structure 52 is provided on the second side 412 of the first corner partition 4111. In this way, there are two elastic structures 5 on the first corner partition 4111. A third elastic structure 53 is provided on the first side 411 of the second corner partition 4112, and a fourth elastic structure 54 is provided on the second side 423 of the second corner partition 4112. In this way, two elastic structures 5 are also provided on the second corner partition 4112.

[0045] The second type of corner partition 42 includes a third corner partition 4213 and a fourth corner partition 4214. Among them, a fifth elastic structure 55 is provided on the third side 423 of the third corner partition 4213, and a sixth elastic structure 56 is provided on the third side 423 of the fourth corner partition 4214. One elastic structure 5 is provided on both the third corner partition 4213 and the fourth corner partition 4214.

[0046] Furthermore, since the first corner partition 4111 and the third corner partition 4213 are on the same side of the electrode contact area 1, and the second corner partition 4112 and the fourth corner partition 4214 are on the same side of the electrode contact area 1. Therefore, the first elastic structure 51 and the fifth elastic structure 55 are on the same side, and the third elastic structure 53 and the sixth elastic structure 56 are on the same side. The first elastic structure 51 and the third elastic structure 53 are arranged oppositely, and the fifth elastic structure 55 and the sixth elastic structure 56 are arranged oppositely, enhancing the symmetry of the arrangement of the elastic structures in the electrode contact area 1.

[0047] The present utility model clarifies the arrangement of the elastic structures. By providing two elastic structures in the first corner partition and the second corner partition, and one spring structure in the third corner partition and the fourth corner partition, the symmetry of the arrangement of the elastic structures in the electrode contact area 1 is ensured, further improving the stability of the flexible microcortical electrode, enabling it to better adapt to the micro-movement of the brain tissue while reducing the damage to the surrounding brain tissue.

[0048] Based on the above embodiments, as Figure 5 shown, the distance between the first elastic structure 51 and the fifth elastic structure 55 is the same as the distance between the third elastic structure 53 and the sixth elastic structure 56.

[0049] Specifically, the distance between the first elastic structure 51 and the fifth elastic structure 55 is the same as the distance between the third elastic structure 53 and the sixth elastic structure 56, further strengthening the symmetry of the arrangement of the elastic structures in the electrode contact area 11, further enhancing the stability of the flexible microcortical electrode, enabling it to better adapt to the micro-movement of brain tissue while reducing damage to the surrounding brain tissue.

[0050] Based on the above embodiments, this embodiment further describes the arrangement manner of the elastic structures. Figure 6 It is a schematic diagram of an elastic structure provided according to an embodiment of the present invention. As Figure 6 shown, the flexible microcortical electrode further includes a flexible substrate 6, and the flexible substrate 6 includes a contact substrate part 61 located in the electrode contact area; the elastic structure 5 is connected to the contact substrate part 61 and is integrally provided.

[0051] Specifically, during the manufacturing process of the flexible microcortical electrode, the flexible substrate 6 of the corner partition 4 is reserved. The reserved area can be a strip-shaped structure, and these structures are folded to form the elastic structure 5. Therefore, the elastic structure 5 is the same as the flexible material and is integrally provided with the flexible substrate 6, thus ensuring the connection and unity of the flexible substrate and the elastic structure 5. The flexible microcortical electrode has compliance, thus adapting to the micro-movement of brain tissue. Usually, the flexible microcortical electrode is placed under the dura mater. One end of the elastic structure 5 contacts the dura mater, and the other end and the electrode contact area are attached to the cerebral cortex. The distance between the dura mater and the cerebral cortex is approximately in the range of 1 mm - 2 mm. Therefore, the elastic expansion and contraction range of the elastic structure 5 can be between 1 mm - 2 mm to ensure that the flexible microcortical electrode does not exceed the safe elastic expansion and contraction range while adapting to the micro-movement of brain tissue and avoiding damage to brain tissue.

[0052] Based on the above embodiments, this embodiment further describes the specific composition manner of the elastic structure. As Figure 6 shown, the elastic structure 5 includes N elastic parts 7, where N ≥ 2 and N is an integer; the N elastic parts 7 are arranged along the thickness direction of the flexible microcortical electrode, and adjacent two elastic parts are connected; the first elastic part 7 is used to contact the meninges, and the Nth elastic part is connected to the contact substrate part.

[0053] Specifically, referring to Figure 6, taking five elastic divisions as an example, if the elastic structure 5 is folded 4 times, five elastic divisions 7 can exist. The five elastic divisions 7 are arranged along the thickness direction of the flexible microcortical electrode, which are the first elastic distribution 71, the second elastic division 72, the third elastic division 73, the fourth elastic division 74, and the fifth elastic division 75 in sequence. Among them, the first elastic division 71 is connected to the meninges, and the fifth elastic division 75 is connected to the contact substrate division 61. By connecting the elastic division to the contact substrate division, the stability of the flexible microcortical electrode is further improved, enabling it to better adapt to the micro-movement of brain tissue while reducing damage to the surrounding brain tissue.

[0054] It should be noted that the number of times the elastic structure 5 is folded can be arbitrarily folded according to the actual situation when implanting into the cerebral cortex. Folding 4 times is only an example and not a limitation.

[0055] Based on the above embodiments, referring to Figure 6 , the thickness m of the elastic division 7 is the same as the thickness of the contact substrate division.

[0056] Specifically, since the elastic structure 5 is formed by folding the flexible substrate structure reserved during the production of the flexible microcortical electrode, the thickness m of the elastic division is the same as the thickness of the substrate division, both being 5μm - 100μm.

[0057] It can be understood that when the thickness of the flexible substrate is less than 5μm, the processing difficulty is high, the cost is high, and the production yield is low. When the thickness of the flexible substrate is greater than 100μm, the relatively thick flexible substrate usually has a large mechanical stiffness, which will cause the flexibility of the flexible microcortical electrode to deteriorate, increase the damage to brain tissue during the implantation process, and increase the risk of inflammatory reaction.

[0058] Based on the above embodiments, in the same elastic structure 5, the widths m of any two elastic divisions are the same. The advantage of this setting is that it can make the elastic structure 5 more regular, make the forces on each elastic division 7 more uniform, and increase the stability of the elastic structure. Further improve the stability of the flexible microcortical electrode, enabling it to better adapt to the micro-movement of brain tissue while reducing damage to the surrounding brain tissue.

[0059] The above specific implementation manners do not constitute a limitation to the protection scope of the present utility model. Those skilled in the art should understand that various modifications, combinations, sub-combinations, and substitutions can be made according to design requirements and other factors. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A flexible micro-cortical electrode for medical in vivo implantation, characterized in that: comprising an electrode contact area, an electrode welding area, and a connection area connecting the electrode contact area and the electrode welding area; The electrode contact area includes a plurality of electrode contacts, the electrode soldering point area is provided with a plurality of electrode soldering points, the connection area is provided with connecting wires, and the connecting wires are electrically connected to the electrode contacts and the electrode soldering points respectively; The electrode contact area includes a corner partition, and the flexible micro-cortical electrode also includes at least one elastic structure, and the elastic structure is arranged in the corner partition.

2. The flexible micro-cortical electrode according to claim 1, characterized in that: The corner partitions include a first type of corner partition and a second type of corner partition, the first type of corner partition is located at a side of the electrode contact area away from the connection area, and the second type of corner partition is located at a side of the electrode contact area close to the connection area; The first type of corner partition includes a first side and a second side, the first side and the second side are connected and their extension directions intersect, and the second type of corner partition includes a third side, the extension direction of the third side is parallel to the extension direction of the first side; The first side and the second side are each provided with at least one elastic structure, and the third side is provided with at least one elastic structure.

3. The flexible micro-cortical electrode according to claim 2, characterized in that: The first type of corner partitions includes a first corner partition and a second corner partition, the second type of corner partitions includes a third corner partition and a fourth corner partition, the first corner partition and the third corner partition are located on the same side of the electrode contact area, and the second corner partition and the fourth corner partition are located on the same side of the electrode contact area; At least one of the elastic structures includes a first elastic structure arranged on the first side in the first corner partition, a second elastic structure arranged on the second side in the first corner partition, a third elastic structure arranged on the first side in the second corner partition, a fourth elastic structure arranged on the second side in the second corner partition, a fifth elastic structure arranged on the third side in the third corner partition, and a sixth elastic structure arranged on the third side in the fourth corner partition.

4. The flexible micro-cortical electrode according to claim 3, characterized in that: The distance between the first elastic structure and the fifth elastic structure is the same as the distance between the third elastic structure and the sixth elastic structure.

5. The flexible micro-cortical electrode according to claim 1, characterized in that: The flexible micro-cortical electrode also includes a flexible substrate; The flexible substrate includes a contact substrate section located in the electrode contact area; The elastic structure is connected to the contact substrate portion and is integrally arranged.

6. The flexible micro-cortical electrode according to claim 5, characterized in that: The elastic structure includes N elastic subdivisions, N ≥ 2 and N is an integer; The N elastic subdivisions are arranged along the thickness direction of the flexible micro-cortical electrode, and two adjacent elastic subdivisions are connected; The first elastic section is used for contacting the meninges, and the Nth elastic section is connected to the contact substrate section.

7. The flexible micro-cortical electrode according to claim 6, characterized in that: The thickness of the spring section is the same as the thickness of the contact substrate section.

8. The flexible micro-cortical electrode according to claim 7, characterized in that: The thickness of the elastic portion is 5 μm-100 μm.

9. The flexible micro-cortical electrode according to claim 6, characterized in that: In the same elastic structure, the widths of any two elastic sections are the same.

10. The flexible micro-cortical electrode according to claim 1, characterized in that: The elastic expansion and contraction range of the elastic structure is between 1mm and 2mm.

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