Pharmaceutical experiment dissolving device

Abstract

The utility model belongs to the technical field of medicine dissolution, and particularly relates to a pharmaceutical experiment dissolution device. The device comprises a horizontally-arranged base, a stirring barrel swinging left and right is hinged to the top of the base, a pesticide inlet pipe is installed at the top of the stirring barrel, a pesticide outlet pipe is installed at the bottom of the stirring barrel, a stirring assembly used for accelerating solution flowing is arranged in the stirring barrel, a first groove is downwards formed in the top of the base, and a movable box is arranged in the first groove; two push plates are vertically fixed to the left side and the right side of the top of the movable box, the lower end of the stirring barrel is located between the two push plates, and a driving assembly used for pushing the movable box to reciprocate left and right is arranged in the movable box. According to the device, medicine and a solution are added into the stirring barrel, under the action of the stirring assembly, flowing of the solution and dissolution of the medicine are accelerated, under the action of the driving assembly, the two push plates are driven to reciprocate left and right and push the stirring barrel to swing left and right in a reciprocating mode, and experimenters are liberated while dissolution of the medicine is accelerated through cooperation of the two push plates and the stirring barrel.

Description

Technical Field

[0001] The utility model belongs to the technical field of drug dissolution, and particularly relates to a dissolution device for pharmaceutical experiments. Background Art

[0002] In pharmaceutical experiments, drug dissolution is a very important step. The process of mixing more than two substances to form a homogeneous phase in a molecular state is called dissolution.

[0003] During the experiment, the drug and the solution are poured into a container, and a stirring rod is used to accelerate the flow rate of the solution to accelerate the dissolution of the drug. Only in this way, there are still a few precipitate particles remaining at the bottom of the container, and the container needs to be shaken by hand to accelerate the dissolution of the drug. For experimenters, it is difficult to perform stirring and shaking simultaneously, which increases the work difficulty and reduces the efficiency of pharmaceutical experiments. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a dissolution device for pharmaceutical experiments, which has a simple structure and can perform stirring and shaking simultaneously to accelerate the dissolution of drugs.

[0005] The dissolution device for pharmaceutical experiments includes a horizontally arranged base. A stirring cylinder that swings left and right is hinged to the top of the base. A medicine inlet pipe is installed at the top of the stirring cylinder, and a medicine outlet pipe is installed at the bottom of the stirring cylinder. A stirring assembly for accelerating the flow of the solution is arranged in the stirring cylinder. A first groove is opened downward on the top of the base. A movable box is arranged in the first groove. Two push plates are vertically fixed on the left and right sides of the top of the movable box. The lower end of the stirring cylinder is located between the two push plates. A driving assembly for pushing the movable box to move left and right reciprocally is arranged in the movable box.

[0006] Further, the driving assembly includes a rotating shaft. The rotating shaft is horizontally installed in the first groove. A driving member for driving the rotating shaft to rotate is installed on the front side wall of the base. A cam is sleeved on the rotating shaft in the movable box. Through grooves that communicate inside and outside are opened at the top and bottom of the movable box. When the cam rotates, it pushes the movable box to move left and right reciprocally.

[0007] Further, sliding plates are horizontally fixed at the bottoms of the left and right side walls of the movable box. Sliding grooves for inserting the sliding plates are opened on the left and right groove walls of the first groove.

[0008] Further, the groove walls of the through grooves are chamfered.

[0009] Further, the stirring assembly includes a central shaft. The central shaft is vertically installed in the stirring cylinder. A driving member for driving the central shaft to rotate is installed at the top of the stirring cylinder. Several blades are fixed on the central shaft.

[0010] Further, two fixing plates distributed front and back are vertically fixed on the top of the base, and the two fixing plates are respectively connected to the mixing cylinder through rotating shafts.

[0011] Further, rollers are installed at the upper ends of the push plates.

[0012] Compared with the prior art, the utility model has the following beneficial effects:

[0013] In the utility model, drugs and solutions are added into the mixing cylinder. Under the action of the mixing assembly, the flow of the solution is accelerated, and the dissolution of the drugs is accelerated. Under the action of the driving assembly, two push plates are driven to reciprocate left and right, and the mixing cylinder is pushed to swing left and right reciprocally. The two cooperate with each other to accelerate the dissolution of the drugs while liberating the experimenters and improving the experimental efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 is a schematic structural diagram of the utility model;

[0015] Figure 2 is Figure 1 the front side view of;

[0016] Figure 3 is a usage state diagram of the utility model;

[0017] Figure 4 is a usage state diagram of the utility model;

[0018] Names of each component in the figure: 1, base; 2, movable box; 3, push plate; 4, roller; 5, mixing cylinder; 6, blade; 7, driving part; 8, medicine inlet pipe; 9, central shaft; 10, fixing plate; 11, rotating shaft; 12, first groove; 13, sliding plate; 14, sliding groove; 15, second groove; 16, cam; 17, through groove. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0019] The following further illustrates the utility model through specific embodiments with reference to the accompanying drawings, but the utility model is not limited thereto. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the present invention.

[0020] Embodiment 1

[0021] A pharmaceutical experiment dissolution device described in this embodiment, as Figures 1 to 4 shown, includes a horizontally arranged base 1. The base 1 is placed flat on the experimental table, and the base 1 is made of plastic or stainless steel;

[0022] A stirring cylinder 5 that swings left and right is hinged to the top of a base 1. The stirring cylinder 5 is vertically arranged on the top of the base 1, and the lower end of the stirring cylinder 5 swings left and right to accelerate the dissolution of the drug. The stirring cylinder 5 is made of glass, and the transparent stirring cylinder 5 is conducive to the user to view the dissolution state of the drug;

[0023] A medicine inlet pipe 8 is installed at the top of the stirring cylinder 5, and a medicine outlet pipe is installed at the bottom of the stirring cylinder 5. Through holes that communicate up and down are provided at both the top and bottom of the stirring cylinder 5. The medicine inlet pipe 8 is vertically inserted into the upper through hole, and the medicine outlet pipe is vertically inserted into the lower through hole. The drug and the solution enter the stirring cylinder 5 through the medicine inlet pipe 8, and the dissolved liquid medicine is discharged from the stirring cylinder 5 through the medicine outlet pipe;

[0024] A central shaft 9 is vertically inserted into the stirring cylinder 5. A through hole that communicates inside and outside is provided in the middle of the top of the stirring cylinder 5, and the central shaft 9 is vertically inserted into the through hole. The central shaft 9 is made of stainless steel; A driving member 7 for driving the central shaft 9 to rotate is installed at the top of the stirring cylinder 5. The driving member 7 is installed at the top of the stirring cylinder 5, and the stirring cylinder 5 is driven to rotate by the driving member 7; A plurality of blades 6 are fixed on the central shaft 9. When the central shaft 9 rotates, the blades 6 rotate together with the central shaft 9 to stir the solution and accelerate the dissolution of the drug. The blades 6 are made of plastic; This paragraph of text as a whole constitutes a stirring assembly for accelerating the flow of the solution. When the stirring assembly is in use, the central shaft 9 is driven to rotate by the driving member 7, and the blades 6 rotate together with the central shaft 9 to stir the solution and accelerate the dissolution of the drug; Of course, the stirring assembly can also be provided with a bearing in the through hole. The outer ring of the bearing is fixed on the hole wall of the through hole, and the upper end of the central shaft 9 is fixed in the inner ring of the bearing. The central shaft 9 is vertically installed in the stirring cylinder 5 through the bearing;

[0025] A first groove 12 is opened downward at the top of the base 1. The first groove 12 has a rectangular structure and is opened downward from the top of the base 1;

[0026] An activity box 2 is arranged in the first groove 12. The activity box 2 is horizontally arranged in the first groove 12 and slides left and right along the length direction of the first groove 12. The activity box 2 is made of plastic;

[0027] Two push plates 3 are vertically fixed on the left and right sides of the top of the activity box 2. The lower end of the stirring cylinder 5 is located between the two push plates 3. There are two push plates 3, which are respectively vertically fixed on the left and right sides of the top of the activity box 2. The lower end of the stirring cylinder 5 is swung left and right by the two push plates 3. The push plates 3 are made of stainless steel;

[0028] A rotating shaft 11 is horizontally installed in the first groove 12. The front end of the rotating shaft 11 passes through the movable box 2 and the base 1 and is located on the front side of the base 1. The rear end of the rotating shaft 11 passes through the movable box 2 and the base 1 and is located on the rear side of the base 1. The rotating shaft 11 is made of stainless steel. A driving member for driving the rotation of the rotating shaft 11 is installed on the front side wall of the base 1. The driving member is installed on the front side wall of the base 1. The driving member is a prior art, generally a motor or a servo motor. The power output end of the motor is connected to the front end of the rotating shaft 11, and the rotating shaft 11 is driven to rotate by the motor. A cam 16 is sleeved on the rotating shaft 11 in the movable box 2. The cam 16 is located in the movable box 2 and rotates together with the rotating shaft 11. The inner side wall of the movable box 2 is pushed by the convex point of the cam 16 to drive the movable box 2 to move left and right reciprocally. Through grooves 17 communicating with the inside and outside are provided at the top and bottom of the movable box 2. There are two through grooves 17, which are respectively provided at the top and bottom of the movable box 2. The two through grooves 17 provide a stroke for the rotation of the cam 16, and at the same time reduce the production material of the movable box 2 and reduce the cost. When the cam 16 rotates, it pushes the inner side wall of the movable box 2 to move left and right reciprocally. By rotating the cam 16, the inner side wall of the movable box 2 is pushed to move, and the left and right reciprocating movement of the movable box 2 is controlled. The whole paragraph constitutes a driving assembly for pushing the movable box 2 to move left and right reciprocally. When the driving assembly is used, the rotating shaft 11 is driven to rotate by the driving member, and the cam 16 rotates together with the rotating shaft 11. When the convex point of the cam 16 rotates to the right side of the rotating shaft 11, as Figure 4 shown, it pushes the right side wall of the movable box 2 to move to the right, and pushes the movable box 2 to move to the right. When the convex point of the cam 16 rotates to the left side of the rotating shaft 11, it pushes the left side wall of the movable box 2 to move to the left, as Figure 3 shown. The cam 16 continues to rotate, and pushes the movable box 2 to rotate left and right in the first groove 12. Of course, a second groove 15 with an arc-shaped structure can be opened downward at the bottom of the first groove 12 in the driving assembly. When the convex point of the cam 16 rotates to the lower side, the second groove 15 provides a stroke for the rotation of the cam 16.

[0029] When this embodiment is used, the medicine and the solution are added into the stirring cylinder 5 through the medicine inlet pipe 8. The flow rate of the solution is accelerated by the stirring assembly, and the dissolution rate of the medicine is accelerated. The movable box 2 is driven to move left and right reciprocally in the first groove 12 by the driving assembly, and the two push plates 3 are driven to move left and right reciprocally. When the push plate 3 moves to the left, the lower end of the stirring cylinder 5 is pushed to the left by the upper end of the right push plate 3, so that the stirring cylinder 5 swings clockwise. When the push plate 3 moves to the right, the lower end of the stirring cylinder 5 is pushed to the right by the upper end of the left push plate 3, so that the stirring cylinder 5 swings counterclockwise. By repeating the above process, the left and right reciprocating swing of the stirring cylinder 5 is controlled, the dissolution of the medicine is accelerated, the experimenter is liberated, and the experimental efficiency is improved.

[0030] Embodiment 2

[0031] This embodiment further illustrates the technology, asFigure 1 As shown, at the bottom of the left and right side walls of the movable box 2, there are two sliding plates 13 horizontally fixed. The two sliding plates 13 are respectively horizontally fixed on the left and right sides of the movable box 2, and the sliding plates 13 are made of plastic.

[0032] On the left and right groove walls of the first groove 12, there are two sliding grooves 14 for inserting the sliding plates 13. The two sliding grooves 14 are respectively opened on the groove walls of the first groove 12. The two sliding plates 13 are respectively inserted into the sliding grooves 14, and the sliding plates 13 slide left and right along the length direction of the sliding grooves 14. The sliding grooves 14 limit the sliding plates 13, improving the stability of the movable box 2 during movement.

[0033] The groove wall of the through groove 17 is chamfered. When the cam 16 rotates, the side wall of the cam 16 presses against the groove wall of the through groove 17, thereby pushing the movable box 2 to move. The chamfered groove wall can reduce the friction between the cam 16 and extend the service life of the movable box 2 and the cam 16.

[0034] Embodiment 3

[0035] This embodiment further illustrates the technology. As Figure 1 and Figure 2 shown, on the top of the base 1, there are two fixing plates 10 vertically fixed in a front-back distribution. The lower ends of the fixing plates 10 are vertically fixed on the top of the base 1.

[0036] The two fixing plates 10 are respectively connected to the mixing drum 5 through rotating shafts. On the rear side wall of the front fixing plate 10, there is a rotating shaft installed. The front side of the mixing drum 5 is fixed on the rotating shaft. On the front side wall of the rear fixing plate 10, there is a rotating shaft installed. The rear side of the mixing drum 5 is fixed on the rotating shaft. The mixing drum 5 swings around the two rotating shafts.

[0037] At the upper ends of the push plates 3, there are two rollers 4 installed. The two rollers 4 are respectively installed at the upper ends of the two push plates 3. The upper ends of the push plates 3 are separated from the side wall of the mixing drum 5 by the rollers 4. By the rotating rollers 4 contacting the side wall of the mixing drum 5, the friction between the push plates 3 and the mixing drum 5 is reduced, and the service life of the push plates 3 and the mixing drum 5 is extended.

Claims

1. A pharmaceutical experimental dissolution device, comprising a horizontally arranged base (1), a stirring drum (5) that swings left and right is hinged on the top of the base (1), a drug inlet pipe (8) is installed on the top of the stirring drum (5), and a drug outlet pipe is installed on the bottom of the stirring drum (5), characterized in that: The stirring drum (5) is provided with a stirring assembly for accelerating the flow of the solution. A first groove (12) is provided downwardly at the top of the base (1). A movable box (2) is provided in the first groove (12). Two push plates (3) are vertically fixed on the left and right sides of the top of the movable box (2). The lower end of the stirring drum (5) is located between the two push plates (3). A driving assembly for pushing the movable box (2) to move back and forth is provided in the movable box (2).

2. The pharmaceutical experimental dissolution device according to claim 1, characterized in that: The driving assembly comprises a rotating shaft (11), the rotating shaft (11) is horizontally inserted into the first groove (12), a driving member for driving the rotating shaft (11) to rotate is installed on the front side wall of the base (1), a cam (16) is mounted on the rotating shaft (11) in the movable box (2), and a through groove (17) communicating with the inside and outside is formed at the top and bottom of the movable box (2), and when the cam (16) rotates, the movable box (2) is pushed to move back and forth left and right.

3. The pharmaceutical experimental dissolution device according to claim 2, characterized in that: Slide plates (13) are horizontally fixed to the bottom of the left and right side walls of the movable box (2), and slide grooves (14) for inserting the slide plates (13) are provided on the left and right groove walls of the first groove (12).

4. The pharmaceutical experimental dissolution device according to claim 3, characterized in that: The groove wall of the through groove (17) has rounded corners.

5. The pharmaceutical experimental dissolution device according to claim 1, characterized in that: The stirring assembly comprises a central shaft (9) which is vertically installed in a stirring drum (5). A driving member (7) for driving the central shaft (9) to rotate is installed on the top of the stirring drum (5). A plurality of blades (6) are fixed on the central shaft (9).

6. The pharmaceutical experimental dissolution device according to claim 1, characterized in that: Two fixing plates (10) distributed front and back are vertically fixed on the top of the base (1), and the two fixing plates (10) are connected to the mixing drum (5) via a rotating shaft respectively.

7. The pharmaceutical experimental dissolution device according to claim 1, characterized in that: The upper ends of the push plates (3) are all equipped with rollers (4).

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