Quantitative subpackaging device for antibody reagent

Abstract

The utility model discloses a quantitative subpackaging device for antibody reagents, which belongs to the field of antibodies and comprises a total antibody reagent tank, an air pressure device and a plurality of quantifying devices, a feed inlet of each quantifying device is provided with a three-way pipe, and the total antibody reagent tank is connected with the feed inlet of the three-way pipe through a reagent branch pipe. The air pressure device is connected with an air inlet of the three-way pipe through an air pressure branch pipe, and a one-way valve for preventing the antibody reagent from flowing back is arranged between the air pressure branch pipe and the air inlet of the three-way pipe. Compared with the prior art, the device has the advantages that the device controls the split charging amount of the quantifying device by replacing the quantifying capsule, and the position of the quantifying capsule is limited and fixed through the resetting device, so that the problem that the whole quantifying device needs to be disassembled after containers with different weights are replaced is avoided.

Description

Technical Field

[0001] The utility model relates to the field of antibodies, in particular to a quantitative dispensing device for antibody reagents. Background Art

[0002] In the existing virus treatment process, the cultivation of antibodies is the key to solving the virus. After the antibodies are tested, quantitative antibody reagents are injected into the patient's body in stages, so that corresponding antibodies are generated in the patient's body to achieve the curative effect. In the production process of antibody reagents, the quantitative dispensing of antibody reagents is the most important process to ensure the safety of patients' lives.

[0003] The existing quantitative dispensing device for antibody reagents usually pours the finished antibody reagent into the total antibody reagent tank. The antibody reagent flows through the reagent branch pipe, electromagnetic on-off valve and three-way pipe in sequence and then flows into the feed port of the quantitative device. Under the high pressure of the air pressure device, the antibody reagent inside the quantitative device flows out from the discharge port of the quantitative device. Because of the blowing of the air pressure (after the high-pressure gas flows out of the air pressure device, it passes through the air pressure branch pipe, check valve and three-way pipe in sequence), there is no residual reagent liquid inside the quantitative device, ensuring the accuracy of the weight of the reagent antibody.

[0004] Although this operation of using a quantitative device to quantify the reagent can ensure the accuracy of the reagent weight in the dispensing container, when replacing containers of different weights, the entire quantitative device needs to be disassembled and then replaced with the corresponding quantitative device, which greatly increases the difficulty of replacement. Summary of the Utility Model

[0005] The technical problem to be solved by the utility model is that when disassembling the quantitative device of the existing quantitative dispensing device for antibody reagents, due to its complex structure, the disassembly is difficult.

[0006] To solve the above technical problems, the technical solution provided by the present utility model is as follows: An antibody reagent quantitative dispensing device, comprising a total antibody reagent tank, a pneumatic device, and a plurality of quantitative devices. A three-way pipe is provided at the feed inlet of the quantitative device. The total antibody reagent tank is connected to the feed inlet of the three-way pipe through a reagent branch pipe. The pneumatic device is connected to the air inlet of the three-way pipe through a pneumatic branch pipe. A one-way valve for preventing the backflow of the antibody reagent is provided between the pneumatic branch pipe and the air inlet of the three-way pipe. Electromagnetic on-off valves are provided between the branch pipe of the one-way valve and the pneumatic branch pipe, and between the liquid feed inlet of the three-way pipe and the branch pipe of the reagent branch pipe. The quantitative device has a double-open structure. A quantitative capsule is provided inside the quantitative device. The quantitative capsule passes through the side wall of the quantitative device. A reset device is provided at the feed inlet of the quantitative capsule. The reset device includes a baffle connected to one side of the feed inlet of the quantitative capsule and a reset spring located between the baffle and the closed end of the quantitative device. A connection port is provided inside the baffle. The discharge outlet of the three-way pipe and the feed inlet of the quantitative capsule are both connected to the two side ports of the connection port through body contact. The three-way pipe is connected to the connection port 323 by welding. A controllable opening is provided on the outlet side of the quantitative capsule.

[0007] As an improvement, the controllable opening includes a closing plate for closing the discharge outlet of the quantitative capsule and a bracket connected to the closing plate. A closing spring is provided between the closing plate and the bracket.

[0008] As an improvement, the closing plate is connected to the bracket through a pin structure. The connecting column inside the bracket passes through the inner hole of the closing spring.

[0009] As an improvement, the quantitative capsule is connected to the inner wall of the quantitative device through body contact. A dispensing container is provided below the discharge outlet of the quantitative device.

[0010] As an improvement, a corresponding closing cover is provided at the input open end of the quantitative device. The branch pipe of the pneumatic branch pipe passes through the closing cover. The reagent branch pipe passes through the side wall of the quantitative device.

[0011] As an improvement, the closing cover is connected to the input open end of the quantitative device through a bolt structure. The baffle and the closing cover are both connected to the reset spring through body contact.

[0012] The advantages of the present utility model compared with the prior art are as follows: The device controls the dispensing amount of the quantitative device by replacing the quantitative capsule, and limits and fixes the position of the quantitative capsule through the reset device, avoiding the problem that the quantitative device needs to be disassembled as a whole after replacing containers of different weights. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is the overall structure diagram of an antibody reagent quantitative dispensing device of the present utility model.

[0014] Figure 2 It is an exploded view of the metering device of an antibody reagent quantitative dispensing device of the present utility model.

[0015] Figure 3 It is a cross-sectional view of the metering device of an antibody reagent quantitative dispensing device of the present utility model.

[0016] Figure 4 It is an enlarged view of the metering capsule of an antibody reagent quantitative dispensing device of the present utility model.

[0017] As shown in the figure: 1. Total antibody reagent tank; 2. Pneumatic device; 3. Metering device; 31. Metering capsule; 311. Controllable opening; 3111. Sealing plate; 3112. Bracket; 3113. Closing spring; 32. Reset device; 321. Baffle; 322. Reset spring; 323. Connection port; 33. Sealing cover; 4. Three-way pipe; 5. Reagent branch pipe; 6. Pneumatic branch pipe; 7. Check valve; 8. Electromagnetic on-off valve; 9. Dispensing container. Specific implementation mode

[0018] The present utility model will be further described in detail below with reference to the accompanying drawings.

[0019] As shown in the attached Figure 1 、 2 、Figure 3, it includes a total antibody reagent tank 1, a pneumatic device 2 and several metering devices 3. A dispensing container 9 is arranged below the discharge port of the metering device 3. A three-way pipe 4 is arranged at the feed port of the metering device 3. The total antibody reagent tank 1 is connected to the feed port of the three-way pipe 4 through a reagent branch pipe 5. The pneumatic device 2 is connected to the air inlet of the three-way pipe 4 through a pneumatic branch pipe 6. A check valve 7 for preventing the reverse flow of the antibody reagent is arranged between the pneumatic branch pipe 6 and the air inlet of the three-way pipe 4. Electromagnetic on-off valves 8 are arranged between the branch pipe of the check valve 7 and the pneumatic branch pipe 6 and between the liquid feed port of the three-way pipe 4 and the branch pipe of the reagent branch pipe 5. The antibody reagent flows from the total antibody reagent tank 1 through the reagent branch pipe 5, the electromagnetic on-off valve 8 and the three-way pipe 4 in sequence and then flows into the feed port of the metering device 3. The inflow of the antibody reagent is controlled by the electromagnetic on-off valve 8, and the reverse flow of the antibody reagent into the pneumatic branch pipe 6 is avoided by the check valve 7.

[0020] Inside the metering device 3, there is a metering capsule 31. The metering capsule 31 passes through the side wall of the metering device 3. The metering capsule 31 is connected to the inner wall of the metering device 3 through body contact. By connecting the metering capsule 31 to the inner wall of the metering device 3 through body contact, the disassembly process of the metering capsule 31 is simple. A reset device 32 is provided at the feed inlet of the metering capsule 31. The reset device 32 includes a baffle 321 connected to one side of the feed inlet of the metering capsule 31 and a reset spring 322 located between the baffle 321 and the closed end of the metering device 3. The metering device 3 has a double-open structure. A corresponding closing cover 33 is provided at the input open end of the metering device 3. The branch pipe of the pneumatic manifold 6 passes through the closing cover 33. The reagent manifold 5 passes through the side wall of the metering device 3. The closing cover 33 is connected to the input open end of the metering device 3 through a bolt structure. Both the baffle 321 and the closing cover 33 are connected to the reset spring 322 through body contact. A connection port 323 is provided inside the baffle 321. The outlet of the three-way pipe 4 and the feed inlet of the metering capsule 31 are both connected to the two side openings of the connection port 323 through body contact. The three-way pipe 4 and the connection port 323 are connected by welding. Through the extrusion of the reset device 32, the metering capsule 31 can be sealed with the inner wall of the metering device 3 to avoid the leakage of the antibody solution.

[0021] As shown in the attached Figure 3 , 4 figure, a controllable opening 311 is provided on the outlet side of the metering capsule 31. The controllable opening 311 includes a closing plate 3111 that closes the discharge port of the metering capsule 31 and a bracket 3112 connected to the closing plate 3111. A closing spring 3113 is provided between the closing plate 3111 and the bracket 3112. The closing plate 3111 is connected to the bracket 3112 through a pin structure. The connecting column inside the bracket 3112 passes through the inner hole of the closing spring 3113. Through the automatic reset function of the closing spring 3113 in the normal state, the closing plate 3111 automatically closes the discharge port after the pneumatic device stops, so as to ensure the accuracy of the capacity of the metering capsule 31.

[0022] During the specific implementation of the utility model, the baffle 321 is placed into the through hole inside the quantitative device 3 from the open end of the quantitative device 3, and the reset spring 322 is placed on both sides of the internal connection port 323 of the baffle 321; the main pipeline of the reagent branch pipe 5 is sleeved on the discharge port of the antibody reagent main tank 1, and it is fixed with items such as cable ties, and the electromagnetic check valve 8 is sleeved on the branch pipe side of the reagent branch pipe 5, and one side of the electromagnetic check valve 8 passes through the through hole of the side wall of the quantitative device 3 and is sleeved on one side of the three-way pipe 4; the main pipeline of the air pressure branch pipe 6 is sleeved on the air outlet of the air pressure device 2, and the open end of the branch pipe of the air pressure branch pipe 6 is sleeved on the electromagnetic check valve 8 (the air pressure branch pipe 6 passes through the closing cover 33), the electromagnetic check valve 8 is sleeved and connected with the one-way valve 7, the one-way valve 7 is fixed to the open end of one side of the three-way pipe 4, and the third port of the three-way pipe 4 is welded to one end of the connecting port 323 inside the baffle 321 by electric welding; align the closing cover 33 with the screw hole at the open end of the quantitative device 3, and screw in the screw to fix it; put the closing spring 3113 on the axial surface of the connecting column inside the bracket 3112, put the closing plate 3111 into the discharge port of the quantitative capsule 31, align the pin column on one side of the closing plate 3111 with the pin hole on the outer wall of the bracket 3112, and fix the pin column by inserting it into the pin hole.

[0023] When in use, select the quantitative capsule 31 corresponding to the capacity of the sub-packaging container 9, move the baffle 321, and insert the quantitative capsule 31 into the interior of the quantitative device 3 from the side opening of the quantitative device 3 (the feed port of the quantitative capsule 31 is inserted into the connecting port 323 inside the baffle 321), loosen the baffle 321, and the quantitative capsule 31 is pressed into the internal through hole of the quantitative device 3 under the action of the return spring 322 to avoid leakage of the antibody reagent solution. When replacing the sub-packaging container 9 with a different capacity, it is only necessary to replace the corresponding quantitative capsule 31 to produce again, which greatly improves the replacement speed of the quantitative device 3.

[0024] The above description of the utility model and its implementation methods is not restrictive. The drawings show only one implementation method of the utility model, and the actual structure is not limited thereto. In short, if ordinary technicians in this field are inspired by it and design structural methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention of the utility model, they should all fall within the protection scope of the utility model.

Claims

1. An antibody reagent quantitative packaging device, comprising an antibody reagent main tank (1), an air pressure device (2) and a plurality of quantitative devices (3), wherein the feed port of the quantitative device (3) is provided with a three-way pipe (4); the antibody reagent main tank (1) is connected to the feed port of the three-way pipe (4) through a reagent bifurcated pipe (5); the air pressure device (2) is connected to the air inlet of the three-way pipe (4) through an air pressure bifurcated pipe (6); a one-way valve (7) is provided between the air pressure bifurcated pipe (6) and the air inlet of the three-way pipe (4) to prevent the antibody reagent from flowing back; an electromagnetic stop valve (8) is provided between the one-way valve (7) and the branch pipe of the air pressure bifurcated pipe (6) and between the liquid feed port of the three-way pipe (4) and the branch pipe of the reagent bifurcated pipe (5); the invention is characterized in that: The quantitative device (3) is a double-open structure. A quantitative capsule (31) is arranged inside the quantitative device (3). The quantitative capsule (31) passes through the side wall of the quantitative device (3). A reset device (32) is arranged at the feed port of the quantitative capsule (31). The reset device (32) comprises a baffle (321) connected to one side of the feed port of the quantitative capsule (31) and a reset spring (322) located between the baffle (321) and the closed end of the quantitative device (3). A connecting port (323) is arranged inside the baffle (321). The discharge port of the three-way pipe (4) and the feed port of the quantitative capsule (31) are both connected to the two side ports of the connecting port (323) through body contact. The three-way pipe (4) and the connecting port (323) are connected by welding. A controllable opening (311) is arranged at the outlet side of the quantitative capsule (31).

2. The antibody reagent quantitative packaging device according to claim 1, characterized in that: The controllable opening (311) comprises a closing plate (3111) for closing a discharge port of a quantitative capsule (31) and a bracket (3112) connected to the closing plate (3111), and a closing spring (3113) is provided between the closing plate (3111) and the bracket (3112).

3. The antibody reagent quantitative packaging device according to claim 2, characterized in that: The closing plate (3111) is connected to the bracket (3112) via a pin structure, and the connecting column inside the bracket (3112) passes through the inner hole of the closing spring (3113).

4. The antibody reagent quantitative packaging device according to claim 1, characterized in that: The quantitative capsule (31) is connected to the inner wall of the quantitative device (3) through body contact, and a dispensing container (9) is provided below the discharge port of the quantitative device (3).

5. The antibody reagent quantitative packaging device according to claim 1, characterized in that: The input open end of the quantitative device (3) is provided with a corresponding closing cover (33), the branch pipe of the air pressure branch pipe (6) passes through the closing cover (33), and the reagent branch pipe (5) passes through the side wall of the quantitative device (3).

6. The antibody reagent quantitative packaging device according to claim 5, characterized in that: The closing cover (33) is connected to the input open end of the quantitative device (3) through a bolt structure, and the baffle (321) and the closing cover (33) are both connected to the return spring (322) through body contact.

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