PCR (Polymerase Chain Reaction) tube annular bracket and constant-temperature nucleic acid amplification analyzer
By designing the PCR tube annular stent and interference-fit test tube holes, the problem that existing equipment cannot directly use linear 8-line PCR tubes is solved, and the effect of simplifying the operation process and improving the efficiency of nucleic acid detection is achieved.
Patent Information
- Application Number
- CN202422016464.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-20
- Publication Date
- 2025-06-13
- Estimated Expiration
- 2034-08-20
AI Technical Summary
Existing equipment cannot directly use straight line 8-line PCR tubes, and they need to be cut open or used single tubes, which leads to cumbersome and time-consuming operation.
A PCR tube annular support is designed, using a circular support and an interference-fit test tube hole, which can accommodate 8 PCR tubes, simplifying the operation process.
By reducing operating steps and saving time, the nucleic acid detection efficiency is improved and the cost of a separate circumference 8-connected pipe mold is saved.
Smart Images

Figure CN222975162U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of medical devices, and particularly relates to a PCR tube annular bracket and a constant temperature nucleic acid amplification analyzer. Background Art
[0002] Nucleic acid detection technology has developed rapidly in recent years, especially in the field of molecular diagnosis POCT. At present, the main POCT nucleic acid detection technology in the market is qPCR nucleic acid detection technology, which has strong specificity, high sensitivity, can quantitatively detect pathogens, and can well achieve high-throughput detection. To achieve the detection purpose of multi-target and multi-sample of the instrument, a linear 8-connected tube is usually used in cooperation with the instrument for testing.
[0003] At present, the common PCR tube consumables in the market adopt single tubes or linear 8-connected tubes, while the detection holes of some instruments on the market are arranged in a circular ring, and the linear 8-connected tubes cannot be directly used. It is necessary to cut the 8-connected tube for use or adopt single tubes. When operating the test, the consumables need to be put in one by one, and the operation is cumbersome and time-consuming. Summary of the Utility Model
[0004] The main purpose of the utility model is to propose a PCR tube annular bracket, which overcomes the above technical problems.
[0005] To achieve the above purpose, the utility model proposes the following technical solutions:
[0006] A PCR tube annular bracket, comprising:
[0007] A bracket body, which is integrally circular ring-shaped, and a plurality of test tube holes are distributed in a circular shape on the bracket body, and each test tube hole can hold a PCR tube.
[0008] Further, the diameter range of the test tube holes is 6 mm to 15 mm.
[0009] Further, the number of the test tube holes is 8.
[0010] Further, the test tube holes and the PCR tubes are assembled by an interference fit method.
[0011] Further, the interference amount of the interference fit is 0.3 mm to 0.5 mm.
[0012] Further, the material of the bracket body is an EVA foam board.
[0013] Further, the hardness of the EVA foam board is 45 degrees.
[0014] Further, the material of the bracket body is silica gel.
[0015] Further, the material of the bracket body is rubber.
[0016] According to another aspect of the present application, there is provided a constant temperature nucleic acid amplification analyzer, which includes the above-mentioned PCR tube circular bracket.
[0017] Through a PCR tube circular bracket of the present utility model, the problem that existing equipment cannot directly use a straight 8-connected row tube and needs to cut the 8-connected row tube for use or use single tubes, and it is necessary to put the consumables into the equipment one by one during the test operation, which is cumbersome and time-consuming, is solved. The number of times of taking individual test tubes multiple times is reduced, the operation of reagent tubes and the addition of reagents are facilitated, the nucleic acid detection efficiency is improved, and the cost of separately opening a circular 8-connected tube mold is also saved. At the same time, the foam bracket for installing PCR single tubes can be independently placed on the desktop and acts as a test tube rack. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] The attached drawings forming a part of this application are used to provide a further understanding of the present utility model. The schematic embodiments of the present utility model and their descriptions are used to explain the present utility model and do not constitute an improper limitation to the present utility model. In the drawings:
[0019] Figure 1 FIG. is a schematic diagram of the cooperation between a PCR tube circular bracket of the present utility model and a PCR tube.
[0020] Figure 2 FIG. is a schematic structural diagram of a constant temperature nucleic acid amplification analyzer including a PCR tube circular bracket of the present utility model.
[0021] Figure 3 FIG. is a top view of a PCR tube circular bracket of the present utility model.
[0022] Figure 4 FIG. is a side sectional view of a PCR tube circular bracket of the present utility model.
[0023] Among them, the above-mentioned attached drawings include the following reference numerals:
[0024] 1, bracket body; 2, test tube hole; 3, PCR tube. DETAILED DESCRIPTION OF THE EMBODIMENTS
[0025] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the attached drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. The following description of at least one exemplary embodiment is actually only illustrative and in no way limits the present utility model and its application or use. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.
[0026] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular forms are also intended to include the plural forms. In addition, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they specify the presence of features, steps, operations, devices, components, and / or combinations thereof.
[0027] Unless otherwise specifically stated, the relative arrangements of the components and steps, numerical expressions, and numerical values set forth in these embodiments do not limit the scope of the present invention. At the same time, it should be understood that for the convenience of description, the dimensions of the various parts shown in the drawings are not drawn in actual proportional relationships. Technologies, methods, and devices known to those of ordinary skill in the relevant art may not be discussed in detail, but where appropriate, the said technologies, methods, and devices should be regarded as part of the authorized specification. In all the examples shown and discussed here, any specific value should be construed as merely exemplary and not as a limitation. Therefore, other examples of the exemplary embodiments may have different values. It should be noted that like reference numerals and letters denote like items in the following drawings, and thus, once an item is defined in one drawing, it does not require further discussion in subsequent drawings.
[0028] Reference is made below to Figures 1 to 4 , for a further description of the present invention:
[0029] A PCR tube annular bracket, comprising:
[0030] A bracket body 1, which is integrally circular, and a plurality of test tube holes 2 are distributed in a circular shape on the bracket body 1, and each test tube hole 2 can hold a PCR tube 3.
[0031] In this embodiment, the test tube hole 2 and the PCR tube 3 are assembled by an interference fit method, and the interference amount of the interference fit is 0.3 mm to 0.5 mm.
[0032] After testing, an interference amount of 0.3 mm to 0.5 mm is an ideal range, which can ensure that the PCR tube 3 can be easily inserted into the test tube hole 2, and can also ensure that the PCR tube can be closely fitted after being inserted into the test tube hole 2, relatively becoming a whole, and achieving the most ideal fitting effect.
[0033] In this embodiment, the diameter range of the test tube hole 2 is 6 mm to 15 mm.
[0034] Generally, the capacity of the PCR tube 3 is between 0.2 ml and 2 ml, and the diameter is between 6 mm and 11 mm. By setting the diameter of the test tube hole 2 between 6 mm and 15 mm according to different usage requirements, different specifications of the PCR tube 3 can be well adapted.
[0035] In this embodiment, the number of test tube holes 2 is 8. Currently, the more common ones are single-tube or linear 8-connected tubes. Setting the number of test tube holes 2 to 8 can better cooperate with the existing PCR tube 3 consumables and achieve fast operation.
[0036] In a preferred embodiment, the material of the bracket body 1 is an EVA foam board, and the hardness of the EVA foam board is 45 degrees.
[0037] Using an EVA foam board with a hardness of 45 degrees can achieve the best use experience and enable a better interference fit effect between the EVA foam board and the PCR tube 3. During actual use, foam boards of other hardnesses can also be selected according to the usage needs to achieve the best use effect.
[0038] In an alternative embodiment, the material of the bracket body 1 is silicone. Because silicone has a certain elasticity and a certain strength, using silicone can also achieve an interference fit with the PCR tube 3 and can achieve a use effect similar to that of the EVA foam board.
[0039] In an alternative embodiment, the material of the bracket body 1 is rubber. Rubber can also meet the usage requirements in terms of elasticity and strength, achieve an interference fit with the PCR tube 3, and achieve a relatively ideal use effect.
[0040] According to another aspect of the present application, a constant-temperature nucleic acid amplification analyzer is provided. The constant-temperature nucleic acid amplification analyzer includes the above-mentioned PCR tube circular bracket.
[0041] The constant-temperature nucleic acid amplification analyzer including the PCR tube circular bracket can cooperate with the PCR tube circular bracket. During use, the PCR tube circular bracket can be placed into the constant-temperature nucleic acid amplification analyzer together with the PCR tube 3. There is no need to take out the PCR tube circular bracket separately, and the nucleic acid analysis test can be directly carried out. The use process is simple and fast, saving operation steps.
[0042] Currently, the detection holes of some instruments on the market are arranged in a circular ring and cannot directly use linear 8-connected tubes. It is necessary to cut the 8-connected tube or use single tubes. When performing the test operation, the consumables need to be placed one by one in sequence, and the operation is cumbersome and time-consuming.
[0043] By using the PCR tube circular bracket and the constant-temperature nucleic acid amplification analyzer in the present application, the operation steps can be reduced and the operation time can be effectively saved.
[0044] The installation operation steps are as follows:
[0045] S1. Install the PCR single tube onto the PCR tube foam bracket. The PCR single tube and the holes on the PCR tube foam bracket form an interference fit to make them an integral body.
[0046] After the reagent preparation is completed, the PCR tube foam holder and the PCR single tube are taken as a whole and directly placed into the constant temperature nucleic acid amplification analyzer for nucleic acid detection.
[0047] The above steps are simple and fast, and compared with the previous methods, the efficiency is effectively improved.
[0048] In addition, the PCR single tube is installed on the PCR tube foam holder. The foam holder with the PCR single tube installed can be independently placed on the desktop, acting as a test tube rack, facilitating the preparation of various reagents. There is no need to put the single tubes one by one multiple times, which simplifies the manual operation. Moreover, the order is determined, ensuring that the loading order of the reagent tubes will not be disordered and guaranteeing the accuracy of nucleic acid detection.
[0049] The PCR tube foam holder is used in cooperation with the constant temperature nucleic acid amplification analyzer as an accessory, which simplifies the manual operation in the experiment, improves the nucleic acid detection efficiency, guarantees the accuracy of nucleic acid detection, and at the same time saves the cost of separately opening the circular 8-tube mold.
[0050] In the description of the present utility model, it should be understood that the orientation or positional relationship indicated by orientation words such as "front, rear, upper, lower, left, right", "horizontal, vertical, perpendicular, horizontal" and "top, bottom", etc. is usually based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present utility model and simplifying the description. Without contrary explanation, these orientation words do not indicate and imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation. Therefore, it should not be construed as limiting the protection scope of the present utility model; the orientation words "inside, outside" refer to the inside and outside relative to the contour of each component itself.
[0051] The above is only the preferred embodiment of the present utility model and is not used to limit the present utility model. For those skilled in the art, the present utility model can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.
Claims
1. A PCR tube ring stand, characterized in that: include: The support body (1) is in the shape of a ring as a whole. A plurality of test tube holes (2) are distributed in a circle on the support body (1). Each of the test tube holes (2) can be placed in a PCR tube (3).
2. A PCR tube ring stand according to claim 1, characterized in that: The diameter of the test tube hole (2) ranges from 6 mm to 15 mm.
3. A PCR tube ring stand according to claim 1, characterized in that: The number of the test tube holes (2) is 8.
4. A PCR tube ring stand according to claim 1, characterized in that: The test tube hole (2) and the PCR tube (3) are assembled in an interference fit manner.
5. A PCR tube ring stand according to claim 4, characterized in that: The interference fit has an interference amount of 0.3 mm to 0.5 mm.
6. A PCR tube ring stand according to claim 1, characterized in that: The support body (1) is made of EVA foam board.
7. A PCR tube ring stand according to claim 6, characterized in that: The hardness of the EVA foam board is 45 degrees.
8. A PCR tube ring stand according to claim 1, characterized in that: The material of the support body (1) is silica gel.
9. A PCR tube ring stand according to claim 1, characterized in that: The material of the bracket body (1) is rubber.
10. A constant temperature nucleic acid amplification analyzer, characterized in that: The constant temperature nucleic acid amplification analyzer comprises the PCR tube ring support according to any one of claims 1 to 9.