Full-automatic wax sealing device for tissue pathological section

Abstract

The utility model discloses a tissue pathological section full-automatic wax sealing device which comprises a slide feeding mechanism, a slide conveying mechanism, a slide collecting mechanism and a controller, and the slide feeding mechanism and the slide collecting mechanism are arranged at the two ends of the slide conveying mechanism respectively. A slide baking mechanism, a wax sealing mechanism and a cooling mechanism are sequentially arranged in the slide conveying mechanism in the conveying direction, and the controller is electrically connected with the slide feeding mechanism, the slide conveying mechanism, the slide collecting mechanism, the slide baking mechanism, the wax sealing mechanism and the cooling mechanism. According to the utility model, the wax sealing efficiency of the tissue slide can be greatly improved, the manpower and consumable cost is saved, and the wax sealing quality of the tissue slide is ensured.

Description

Technical Field

[0001] This application relates to the technical field of pathological tissue wax sealing, and particularly relates to a fully automatic wax sealing device for tissue pathological sections. Background Art

[0002] In the pathology departments of the medical field and various medical and biological pathology laboratories, tissue pathological sections play a crucial role and are of great importance in disease diagnosis and research.

[0003] When performing pathological section operations, it is necessary to first trim the tissue wax block section surface, and then the sectioning can be carried out, which will cause waste of some tissue specimens. In order to make the best use of tissue specimens, usually multiple sections of the tissue are made at one time. At the same time, to ensure that the antigen proteins and DNA in the tissue sections are not oxidized and damaged, usually the cut tissue glass slides are wax-sealed, and then they are properly stored in a low-temperature environment of -4°C or -20°C to preserve the immune characteristics of the tissue for a long time. When the experiment requires, subsequent experimental operations can be carried out by dewaxing the wax-sealed tissue glass slides, thus providing strong support for experimental research.

[0004] Currently, when wax-sealing tissue sections, first, the cut tissue glass slides need to be placed in an oven at 65°C - 75°C for 10 to 15 minutes of slide baking treatment. After the paraffin melts, the tissue adheres tightly to the surface of the glass slide. Then, the tissue surface of the tissue glass slide is contacted with a heating table filled with liquid paraffin to ensure that the liquid paraffin completely covers the tissue surface. After the paraffin cools, the solidified paraffin will cover the tissue surface, effectively isolating air and protecting the tissue integrity. However, the above method has the following limitations and disadvantages: 1. Currently, when wax-sealing tissue glass slides, experimental equipment and instruments such as slide racks or slide boxes, ovens, heating tables, and cold tables are required, involving many instruments and inconvenient operations; 2. Currently, after sectioning tissue wax blocks, the cut tissue glass slides need to be placed in a constant-temperature oven at 65°C - 75°C for slide baking, and the slide baking time will increase as the amount of slide baking increases, with low efficiency; 3. Currently, when wax-sealing tissue glass slides, in order to make the tissue glass slides contact the melted paraffin on the heating table as quickly as possible and make it better cover the tissue surface, the baked tissue glass slides need to be contacted with the melted paraffin in a relatively high-temperature state. The purpose of this operation is to make a thin layer of liquid paraffin cover the surface of the tissue glass slide, which not only saves the consumption of paraffin but also reduces the consumption of dewaxing agent before subsequent experiments; 4. After the tissue glass slides are wax-sealed, they need to wait for the paraffin to cool and solidify before they can be manually collected into a slide box, and this step also takes a lot of time. For this reason, the present utility model proposes a fully automatic wax sealing device for tissue pathological sections. Content of the Utility Model

[0005] The embodiment of the present application provides a fully automatic wax sealing device for tissue pathological sections, which can greatly improve the efficiency of wax sealing of tissue glass slides, save labor and consumable costs, and ensure the wax sealing quality of tissue glass slides.

[0006] In view of this, the present application provides a fully automatic wax sealing device for tissue pathological sections, including: a glass slide loading mechanism, a glass slide conveying mechanism, a glass slide collecting mechanism, and a controller;

[0007] The glass slide loading mechanism and the glass slide collecting mechanism are respectively arranged at both ends of the glass slide conveying mechanism;

[0008] A baking mechanism, a wax sealing mechanism, and a cooling mechanism are sequentially arranged in the glass slide conveying mechanism along the conveying direction;

[0009] The controller is electrically connected to the glass slide loading mechanism, the glass slide conveying mechanism, the glass slide collecting mechanism, the baking mechanism, the wax sealing mechanism, and the cooling mechanism respectively.

[0010] Optionally, the glass slide loading mechanism includes a first lifting platform, a first placement rack slidably mounted on the first lifting platform in the vertical direction, and a first ejector pin for pushing the tissue glass slides on the first placement rack onto the glass slide conveying mechanism.

[0011] Optionally, the glass slide conveying mechanism includes an annular conveying track;

[0012] A hollow space is formed in the middle of the annular conveying track, and the baking mechanism, the wax sealing mechanism, and the cooling mechanism are all located in the hollow space;

[0013] Photoelectric induction devices for sensing the position of tissue glass slides are arranged at the positions of the baking mechanism, the wax sealing mechanism, and the cooling mechanism;

[0014] The photoelectric induction device is electrically connected to the controller.

[0015] Optionally, a limiting groove for positioning tissue glass slides is arranged on the annular conveying track.

[0016] Optionally, the glass slide collecting mechanism includes a second lifting platform, a second placement rack slidably mounted on the second lifting platform in the vertical direction, and a second ejector pin for pushing the tissue glass slides on the glass slide conveying mechanism into the second placement rack.

[0017] Optionally, the baking mechanism is a constant temperature heating blower.

[0018] Optionally, the wax sealing mechanism includes a wax melting cylinder for melting and storing paraffin wax, and a wax melting spray head for evenly spraying the liquid paraffin wax in the wax melting cylinder on the tissue surface of the tissue glass slide.

[0019] Optionally, the cooling mechanism is a constant temperature refrigeration blower.

[0020] Optionally, temperature monitoring devices are provided on the slide baking mechanism, the wax sealing mechanism, and the cooling mechanism.

[0021] Optionally, the temperature monitoring device is an electronic thermometer.

[0022] From the above technical solutions, it can be seen that the embodiments of the present application have the following advantages: The fully automatic wax sealing device for tissue pathological sections can realize the entire process of tissue slides from baking, wax sealing, cooling to collection, greatly reducing the time required for traditional tissue slide wax sealing, improving the quality of tissue slide wax sealing, effectively avoiding the failure of tissue characteristics caused by incomplete wax sealing, providing guarantee for subsequent experiments, and at the same time greatly reducing the labor cost, reagent usage cost and the usage rate of experimental equipment. Description of the Drawings

[0023] Figure 1 is a schematic structural diagram of the fully automatic wax sealing device for tissue pathological sections in the embodiment of the present application;

[0024] Figure 2 is a schematic structural diagram of the first vertical slide rail in the embodiment of the present application;

[0025] Among them, the reference numerals are:

[0026] 1 - First lifting platform, 2 - Second lifting platform, 3 - Ring conveyor track, 4 - Slide baking mechanism, 5 - Wax melting tank, 6 - Cooling mechanism, 7 - Control panel, 8 - Photoelectric induction device, 9 - Electronic thermometer, 10 - First placement rack, 11 - First ejector pin, 12 - Second placement rack, 13 - Second ejector pin, 14 - Wax melting spray head, 15 - First vertical slide rail. Detailed Embodiments

[0027] In order to enable those skilled in the art to better understand the solutions of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.

[0028] In the description of the present application, it should be noted that the orientation or positional relationship indicated by terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be construed as a limitation to the present application. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0029] Unless otherwise clearly specified and defined, the terms "install", "connect", "couple" shall be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific circumstances.

[0030] The present application provides an embodiment of a fully automatic wax sealing device for tissue pathological sections. For details, please refer to Figure 1 .

[0031] The fully automatic wax sealing device for tissue pathological sections in this embodiment includes: a slide loading mechanism, a slide conveying mechanism, a slide collecting mechanism, and a controller. The slide loading mechanism and the slide collecting mechanism are respectively arranged at both ends of the slide conveying mechanism. Along the conveying direction in the slide conveying mechanism, a slide baking mechanism 4, a wax sealing mechanism, and a cooling mechanism 6 are sequentially arranged. The controller is electrically connected to the slide loading mechanism, the slide conveying mechanism, the slide collecting mechanism, the slide baking mechanism 4, the wax sealing mechanism, and the cooling mechanism 6 respectively.

[0032] It should be noted that: this fully automatic wax sealing device for tissue pathological sections can realize the entire process of tissue slide baking, wax sealing, cooling, and collection, greatly reducing the time required for traditional tissue slide wax sealing, improving the quality of tissue slide wax sealing, effectively avoiding the failure of tissue characteristics caused by incomplete wax sealing, providing guarantee for subsequent experiments, and at the same time greatly reducing the labor cost, reagent usage cost, and the usage rate of experimental equipment.

[0033] The above is the first embodiment of a fully automatic wax sealing device for tissue pathological sections provided by the embodiments of the present application. The following is the second embodiment of a fully automatic wax sealing device for tissue pathological sections provided by the embodiments of the present application. For details, please refer to Figure 1 and Figure 2 .

[0034] The fully automatic wax-sealing device for tissue pathological sections in this embodiment includes: a slide loading mechanism, a slide conveying mechanism, a slide collecting mechanism, and a controller. The slide loading mechanism and the slide collecting mechanism are respectively arranged at both ends of the slide conveying mechanism. Along the conveying direction in the slide conveying mechanism, a slide baking mechanism 4, a wax-sealing mechanism, and a cooling mechanism 6 are sequentially arranged. The controller is electrically connected to the slide loading mechanism, the slide conveying mechanism, the slide collecting mechanism, the slide baking mechanism 4, the wax-sealing mechanism, and the cooling mechanism 6. Specifically, the controller can be a control panel 7, and the staff can use the control panel 7 to set the duration, temperature, and intensity of each stage by themselves, making the operation simpler and more convenient.

[0035] The slide loading mechanism includes a first lifting platform 1, a first placement rack 10 slidably installed on the first lifting platform 1 in the vertical direction, and a first ejector pin 11 for pushing the unsealed tissue slides on the first placement rack 10 onto the slide conveying mechanism. Specifically, a first vertical slide rail 15 for slidably connecting with the first placement rack 10 is arranged on the first lifting platform 1, and the first placement rack 10 is detachably installed on the first lifting platform 1.

[0036] It can be understood that during use, the just fished tissue slides can be placed on the first placement rack 10 in the required order, and then the first placement rack 10 is installed on the first lifting platform 1. When the slide loading mechanism starts to operate, the first ejector pin 11 will push out the unsealed tissue slide at the bottom of the first placement rack 10. At this time, the first lifting platform 1 drives the first placement rack 10 to move down along the first vertical slide rail 15, so that the tissue slides are pushed out in order.

[0037] The slide conveying mechanism is used to continuously transport single tissue slides pushed out from the first placement rack 10. Specifically, the slide conveying mechanism includes an annular conveying track 3. There is a hollow space in the middle of the annular conveying track 3. The slide baking mechanism 4, the wax-sealing mechanism, and the cooling mechanism 6 are all located in the hollow space. Photoelectric induction devices 8 for sensing the position of tissue slides are arranged at the positions of the slide baking mechanism 4, the wax-sealing mechanism, and the cooling mechanism 6. The photoelectric induction devices 8 are electrically connected to the controller, which can ensure the stable operation of the wax-sealing process.

[0038] Limit slots for positioning tissue slides are arranged on the annular conveying track 3.

[0039] The slide collecting mechanism includes a second lifting platform 2, a second placement rack 12 slidably installed on the second lifting platform 2 in the vertical direction, and a second ejector pin 13 for pushing the wax-sealed tissue slides on the slide conveying mechanism into the second placement rack 12. Specifically, a second vertical slide rail for slidably connecting with the second placement rack 12 is arranged on the second lifting platform 2. The second placement rack 12 is detachably installed on the second lifting platform 2. The second lifting platform 2 is used to drive the second placement rack 12 to move up and down along the second vertical slide rail to ensure that the tissue slides are collected in order.

[0040] It should be noted that: after the second ejector pin 13 pushes the tissue slide with wax sealed on the slide conveying mechanism into the second placement rack 12, the second lifting platform 2 operates to drive the second placement rack 12 to move downward, so as to ensure that the next tissue slide can smoothly enter the second placement rack 12, realizing the stacking and collection of tissue slides.

[0041] The slide baking mechanism 4 can be a constant-temperature heating blower, which can quickly bake and fix the tissue slide with just fished tissue through the constant-temperature heating blower.

[0042] The wax sealing mechanism includes a wax melting cylinder 5 for melting and storing paraffin wax and a wax melting spray head 14 for evenly spraying the liquid paraffin wax in the wax melting cylinder 5 on the tissue surface of the tissue slide.

[0043] The cooling mechanism 6 can be a constant-temperature refrigerating blower, through which the liquid paraffin wax covering the surface of the tissue slide can be quickly cooled.

[0044] Temperature monitoring devices are arranged on the slide baking mechanism 4, the wax sealing mechanism and the cooling mechanism 6, and the temperature monitoring devices are used to monitor the real-time temperatures of the constant-temperature heating blower, the constant-temperature refrigerating blower and the wax melting cylinder 5.

[0045] The temperature monitoring device can be an electronic thermometer 9.

[0046] During specific implementation, power is turned on and wait for the control panel 7 to prompt normal operation. Check whether the content of liquid paraffin wax in the wax melting cylinder 5 is sufficient, then load the tissue slide to be wax sealed into the first placement rack 10, load the first placement rack 10 onto the first lifting platform 1, operate the control panel 7, and start running according to the pre-set wax sealing program. Specifically, during slide fishing, the tissue slides with fished tissue are collected in the first placement rack 10 in the required order, the first placement rack 10 with loaded tissue slides is installed on the first lifting platform 1, the second placement rack 12 is installed on the second lifting platform 2, the slide feeding mechanism operates, and the tissue slide to be wax sealed is pushed into the limiting groove on the annular conveying track 3 through the first ejector pin 11. The annular conveying track 3 transports the tissue slide from the starting point to each working procedure. When the tissue slide reaches the baking stage, the constant-temperature heating blower that has reached the set temperature starts to bake the tissue slide. After the baking stage ends, the tissue slide is transported by the annular conveying track 3 to the wax sealing stage. At this time, the liquid paraffin wax in the wax melting cylinder 5 is evenly and densely sprayed on the tissue surface of the tissue slide by the wax melting spray head 14. After that, the tissue slide covered with liquid paraffin wax enters the cooling stage, and the constant-temperature refrigerating blower that has reached the set temperature starts to quickly cool the tissue slide. The cooled tissue slide is collected in the second placement rack 12 through the second ejector pin 13.

[0047] The fully automatic wax sealing device for tissue pathological sections can control the action time of each stage of wax sealing, the temperatures of the constant temperature heating blower and the constant temperature cooling blower, the wax output of the wax melting nozzle 14, and the temperature of the wax melting cylinder 5 through the control panel 7. It can greatly improve the efficiency of wax sealing of tissue glass slides, reduce the usage times of equipment such as ovens, heaters, and cold tables, and at the same time reduce labor costs and reagent consumption, ensure the wax sealing quality of tissue glass slides, and provide reliable experimental materials for medical pathological biological research, thus promoting the development and progress of medical science.

[0048] As mentioned above, the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features; and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the various embodiments of the present application.

Claims

1. A fully automatic wax sealing device for tissue pathology sections, characterized in that: include: Slide feeding mechanism, slide conveying mechanism, slide collecting mechanism and controller; The glass slide feeding mechanism and the glass slide collecting mechanism are respectively arranged at two ends of the glass slide conveying mechanism; The slide conveying mechanism is provided with a slide baking mechanism, a wax sealing mechanism and a cooling mechanism in sequence along the conveying direction; The controller is electrically connected to the glass slide loading mechanism, the glass slide conveying mechanism, the glass slide collecting mechanism, the glass slide baking mechanism, the wax sealing mechanism and the cooling mechanism respectively.

2. The fully automatic wax sealing device for tissue pathology sections according to claim 1, characterized in that: The slide loading mechanism comprises a first lifting platform, a first placement rack slidably mounted on the first lifting platform in a vertical direction, and a first striker for pushing the tissue slide on the first placement rack to the slide conveying mechanism.

3. The fully automatic wax sealing device for tissue pathology sections according to claim 1, characterized in that: The slide conveying mechanism comprises an annular conveying track; The middle part of the annular conveying track has a hollow space, and the slice baking mechanism, the wax sealing mechanism and the cooling mechanism are all located in the hollow space; Photoelectric sensing devices for sensing the position of tissue slides are arranged at the positions of the baking mechanism, the wax sealing mechanism and the cooling mechanism; The photoelectric sensing device is electrically connected to the controller.

4. The fully automatic wax sealing device for tissue pathology sections according to claim 3, characterized in that: The annular conveying track is provided with a limiting groove for positioning the tissue slide.

5. The fully automatic wax sealing device for tissue pathology sections according to claim 1, characterized in that: The slide collection mechanism includes a second lifting platform, a second placement rack slidably mounted on the second lifting platform in a vertical direction, and a second striker for pushing the tissue slides on the slide conveying mechanism into the second placement rack.

6. The fully automatic wax sealing device for tissue pathology sections according to claim 1, characterized in that: The slice baking mechanism is a constant temperature heating blower.

7. The fully automatic wax sealing device for tissue pathology sections according to claim 1, characterized in that: The wax sealing mechanism comprises a wax melting tank for melting and storing paraffin and a wax melting nozzle for evenly spraying the liquid paraffin in the wax melting tank onto the tissue surface of the tissue slide.

8. The fully automatic wax sealing device for tissue pathology sections according to claim 1, characterized in that: The cooling mechanism is a constant temperature refrigeration blower.

9. The fully automatic wax sealing device for tissue pathology sections according to claim 1, characterized in that: The slice baking mechanism, the wax sealing mechanism and the cooling mechanism are all provided with temperature monitoring devices.

10. The fully automatic wax sealing device for tissue pathology sections according to claim 9, characterized in that: The temperature monitoring device is an electronic thermometer.

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