Efficient liquid-based cell dyeing machine

Abstract

The utility model discloses an efficient liquid-based cell dyeing machine, which relates to the technical field of medical instruments and comprises a dyeing bin, a control table is arranged on one side of the dyeing bin, and a driving component is arranged on the inner side of the dyeing bin; the sampling transposition assembly is arranged in the dyeing bin, the sampling transposition assembly comprises a transposition part, a clamping part and an anti-falling positioning part, and the transposition part is used for switching the positions of the sampling heads at different positions to sample one by one. The mounting disc is driven by the motor to rotate, the double-groove clamping frames at different positions are sequentially rotated to the outer sides of the positioning blocks, the clamping columns are clamped into the clamping grooves under the thrust of the springs, and the positioning blocks are connected with the corresponding double-groove clamping frames in a clamped mode; under the driving of the Y-axis driving mechanism, the positioning block, the double-groove clamping frame and the sampling head are driven to move downwards to a sampling position for sampling in sequence, multiple groups of samples are sampled and lofted at a time, the operation time is shortened, and the working efficiency of the dyeing machine is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, and particularly relates to an efficient liquid-based cell staining machine. Background Art

[0002] Cell staining is an important experimental technique widely used in the fields of biology and medicine. By adding a stain to cells, the internal structure or specific components of the cells are made visible, facilitating observation, analysis, and research. Common cell staining methods include adsorption staining, permeability staining, histological staining, etc. Different staining methods are suitable for different experimental purposes and requirements. A cell staining machine is a device used to stain cells in biological samples. By controlling parameters such as temperature, time, and the circulation of the staining solution, the cells are brought into full contact with the staining solution, thereby realizing the automated processing of cell staining.

[0003] After retrieval, a liquid-based cell sedimentation automatic staining machine with the publication number CN215525266U includes: an adhesive slide carrying structure for carrying an adhesive slide and a staining chamber provided on the adhesive slide; a sample carrying structure for placing a pipette required for staining and a test tube containing a sample solution; a reagent chamber for respectively containing a plurality of reagents for staining; a first conduit for injecting a buffer solution into the test tube, obtaining a pipette on the sample carrying structure, and sucking the sample solution from the corresponding test tube through the pipette; a first motion mechanism connected to the first conduit for driving the first conduit to move between the adhesive slide carrying structure and the sample carrying structure; a second conduit connected to the reagent chamber for injecting a reagent into the corresponding staining chamber; a second motion mechanism connected to the second conduit for driving the second conduit to move between a plurality of staining chambers. The beneficial effect is that the utility model is simple to operate and can realize the automation of cell slide staining.

[0004] In this disclosed patent, only one first conduit is provided. During sampling, only one sample can be taken at a time. After taking the sample and placing it in the designated position, it returns to the sampling area again for sampling and placing. Working in this way in a cycle consumes too much time, thereby reducing the overall working efficiency of the staining machine. Content of the Utility Model

[0005] The purpose of the utility model is to provide an efficient liquid-based cell staining machine, which solves the problem that in the existing staining machine, only one sample can be taken at a time by the first conduit. After taking the sample and placing it in the designated position, it returns to the sampling area again for sampling and placing. Working in this way in a cycle consumes too much time, thereby reducing the overall working efficiency of the staining machine.

[0006] The utility model solves the above technical problems through the following technical solutions. The utility model includes:

[0007] Dyeing bin, a control console is arranged on one side of the dyeing bin, and a driving component is arranged inside the dyeing bin;

[0008] Sampling and transposition component, the sampling and transposition component is arranged inside the dyeing bin, and the sampling and transposition component includes a transposition member, a clamping member and an anti - detachment positioning member. The transposition member is used to convert the positions of sampling heads at different positions for sampling one by one. The clamping member is used to clamp the transposition member and the driving component, and the anti - detachment positioning member is used to prevent the transposition member from sliding down due to gravity;

[0009] The transposition member includes a mounting frame, a motor is fixed below the mounting frame, a mounting disc rotates below the mounting frame, an annular groove is formed at the top of the mounting disc, a plurality of card slots are formed on the outer side of the mounting disc, and the card slots are communicated with the annular groove, and a double - groove clamping frame is arranged inside the card slots.

[0010] Preferably, the clamping member includes a spring, a clamping column and a positioning block. One end of the spring is fixed inside the double - groove clamping frame, the other end of the spring is fixedly connected with the clamping column, two clamping grooves are formed on the outer surface of the positioning block, and the positioning block slides inside the double - groove clamping frame.

[0011] Preferably, the anti - detachment positioning member includes an L - shaped plate and a plurality of rubber positioning strips. The L - shaped plate is fixed below the double - groove clamping frame, the rubber positioning strips are fixed on the outer surface of the L - shaped plate, a plurality of connecting grooves are formed inside the mounting disc, and the L - shaped plate slides inside the connecting grooves.

[0012] Preferably, the driving component includes an X - axis driving mechanism fixed inside the dyeing bin, a Z - axis driving mechanism is installed below the X - axis driving mechanism, and a Y - axis driving mechanism is installed on one side of the Z - axis driving mechanism.

[0013] Preferably, the mounting frame is fixed on the outer surface of the Y - axis driving mechanism.

[0014] Preferably, the positioning block is fixed at one end of the telescopic rod of the Y - axis driving mechanism.

[0015] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0016] In the present utility model, the motor drives the mounting disc to rotate, and the double - groove clamping frames at different positions are sequentially rotated to the outside of the positioning block. The clamping column is pushed by the spring and clamped into the clamping groove, so that the positioning block is clamped with the corresponding double - groove clamping frame. Driven by the Y - axis driving mechanism, the positioning block, the double - groove clamping frame and the sampling head are driven to move down to the sampling position for sequential sampling. Multiple groups of sampling and sample placing are carried out at one time, reducing the operation time, thereby helping to improve the working efficiency of the dyeing machine. Description of the Drawings

[0017] Figure 1 is the front view structural schematic diagram of the present utility model;

[0018] Figure 2 is the cross-sectional view of the present utility model;

[0019] Figure 3 is the partial exploded cross-sectional view of the sampling and transposition assembly in the present utility model;

[0020] Figure 4 is Figure 3 the enlarged structural schematic diagram of part A in

[0021] The numbers in the figure represent:

[0022] 1 - Dyeing bin; 2 - Console; 3 - Sampling and transposition assembly; 31 - Mounting frame; 32 - Motor; 33 - Mounting disc; 34 - Annular groove; 35 - Card slot; 36 - Double - groove clamping frame; 37 - Spring; 38 - Clamping post; 39 - Positioning block; 310 - Clamping groove; 311 - L - shaped plate; 312 - Rubber positioning strip; 313 - Connection groove; 4 - Driving assembly; 41 - X - axis driving mechanism; 42 - Z - axis driving mechanism; 43 - Y - axis driving mechanism. Specific embodiments

[0023] The following further elaborates on the above - mentioned and additional technical features and advantages of the present utility model in conjunction with the accompanying drawings.

[0024] This embodiment provides a technical solution: An efficient liquid - based cytology staining machine, as Figure 1 shown, includes a dyeing bin 1, a sampling and transposition assembly 3, and a driving assembly 4. The sampling and transposition assembly 3 is arranged inside the dyeing bin 1, and the driving assembly 4 is arranged inside the dyeing bin 1. The driving assembly 4 is used to drive the sampling and transposition assembly 3 to move positions in the dyeing bin 1 for automated work. And a console 2 is arranged on one side of the dyeing bin 1. The console 2 controls the sampling and transposition assembly 3, the driving assembly 4, etc. to operate automatically through a PLC controller for dyeing;

[0025] As Figures 1 - 4As shown, the sampling transposition component 3 includes a transposition member, a clamping member and an anti-slip positioning member. A sampling head is fixed below each double-slot clamping frame 36 in the transposition member. The transposition member is used to switch the positions of the sampling heads at different positions for sampling one by one. Multiple sampling heads are used for sampling at one time, which reduces the time required for sampling back and forth and helps improve the dyeing efficiency. The clamping member is used to clamp the transposition member and the driving component 4, mainly to connect the positioning block 39 and the Y-axis driving mechanism 43. As the Y-axis driving mechanism 43 rises and falls, the positioning block 39 is driven to rise and fall, so that the double-slot clamping frame 36 and one of the sampling heads are lifted and lowered to complete a sampling work. The anti-slip positioning member is used to prevent the transposition member from sliding down due to gravity. When one of the sampling heads is sampling, the other sampling heads will not fall and affect the work of the sampling head that is sampling.

[0026] like Figure 3 As shown, the position change member includes a mounting frame 31, a motor 32 is fixed below the mounting frame 31, a mounting plate 33 is rotatably arranged below the mounting frame 31, one end of the output shaft of the motor 32 is fixed at the upper center of the mounting plate 33, and is used to drive the mounting plate 33 and the double-slot clamping frame 36, an annular groove 34 is provided on the top of the mounting plate 33, a plurality of clamping grooves 35 are provided on the outer side of the mounting plate 33, and the clamping grooves 35 are connected with the annular grooves 34, a double-slot clamping frame 36 is arranged inside the clamping grooves 35, and the middle groove of the double-slot clamping frame 36 has the same shape as the annular groove 34, and the disconnected annular groove 34 groove bodies are spliced ​​into a whole.

[0027] like Figures 3 - 4 As shown, the clamping member includes a spring 37, a clamping column 38 and a positioning block 39. The double-slot clamping frame 36 is U-shaped and has two inner grooves, such as Figure 4 As shown, the two inner grooves are opposite to each other, and there are multiple groups of clips, one of which is in each inner groove. One end of the spring 37 is fixed to the inside of the double-slot clamping frame 36, and the other end of the spring 37 is fixedly connected to the clamping column 38. The clamping column 38 slides in the inner groove, and when the spring 37 is in its original state and length, one end of the clamping column 38 extends to the inner side of the double-slot clamping frame 36, and the outer surface of the positioning block 39 is provided with two clamping grooves 310, the size of the clamping grooves 310 is adapted to the size of the clamping column 38, and the positioning block 39 slides on the inner side of the double-slot clamping frame 36.

[0028] like Figure 4As shown in the figure, the anti - detachment positioning member includes an L - shaped plate 311 and a plurality of rubber positioning strips 312. The L - shaped plate 311 is fixed below the double - groove clamping frame 36, and the rubber positioning strips 312 are fixed on the outer surface of the L - shaped plate 311. A plurality of connecting grooves 313 are formed inside the mounting disc 33. The size of the connecting grooves 313 is adapted to the size of the L - shaped plate 311, and strip - shaped grooves adapted to the shape and size of the rubber positioning strips 312 are formed on the inner side of the connecting grooves 313. The rubber positioning strips 312 are clamped inside the strip - shaped grooves to fix the position of the L - shaped plate 311, and the L - shaped plate 311 slides inside the connecting grooves 313.

[0029] As Figures 2 - 3 As shown in the figure, the driving assembly 4 includes an X - axis driving mechanism 41 fixed inside the dyeing chamber 1. A Z - axis driving mechanism 42 is installed below the X - axis driving mechanism 41, and a Y - axis driving mechanism 43 is installed on one side of the Z - axis driving mechanism 42. The X - axis driving mechanism 41, the Z - axis driving mechanism 42, and the Y - axis driving mechanism 43 can move the sampling and transposition assembly 3 to change positions for dyeing. The mounting frame 31 is fixed on the outer surface of the Y - axis driving mechanism 43. As the X - axis driving mechanism 41 and the Z - axis driving mechanism 42 move positions, and are not affected by the lifting drive of the Y - axis driving mechanism 43, the positioning block 39 is fixed at one end of the telescopic rod of the Y - axis driving mechanism 43. As the Y - axis driving mechanism 43 lifts and drives, the double - groove clamping frame 36 and the sampling head are lifted and lowered.

[0030] During use, the motor 32 drives the mounting disc 33 to rotate, rotates the double - groove clamping frame 36 to the outside of the positioning block 39. The clamping post 38 is pushed by the spring 37 and is inserted into the clamping groove 310 to clamp the positioning block 39 with the corresponding double - groove clamping frame 36. The telescopic rod of the Y - axis driving mechanism 43 extends to push the positioning block 39 and the double - groove clamping frame 36 downward, thereby pushing the corresponding sampling head downward to the sampling position for sampling. Under the guiding of the L - shaped plate 311 and the connecting groove 313, the double - groove clamping frame 36 is always kept in a connected state with the mounting disc 33, and can help stabilize the lifting trajectory of the double - groove clamping frame 36. After sampling, the Y - axis driving mechanism 43 pulls the positioning block 39 and the double - groove clamping frame 36 back to the original position. Due to the clamping and limiting of the rubber positioning strip 312 and the strip - shaped groove, the double - groove clamping frame 36 is fixed in the corresponding card slot 35, preventing the sampling heads from affecting each other during the sampling work. The motor 32 continues to drive the mounting disc 33 to rotate until the next double - groove clamping frame 36 is rotated to the corresponding position of the positioning block 39, and then the next sampling work can be carried out. Multiple groups of sampling and sample placement are carried out at one time, reducing the operation time, thereby helping to improve the working efficiency of the dyeing machine.

[0031] The above are only the preferred embodiments of the present utility model, which are merely illustrative rather than restrictive to the present utility model. Those skilled in the art understand that many changes, modifications or even equivalents can be made to it within the spirit and scope defined by the claims of the present utility model, but all of them will fall within the protection scope of the present utility model.

Claims

1. A high-efficiency liquid-based cell staining machine, characterized in that: include: A dyeing chamber (1), wherein a control console (2) is arranged on one side of the dyeing chamber (1), and a driving assembly (4) is arranged on the inner side of the dyeing chamber (1); A sampling transposition component (3), the sampling transposition component (3) is arranged inside the dyeing chamber (1), the sampling transposition component (3) comprises a transposition member, a clamping member and an anti-slipping positioning member, the transposition member is used to switch the positions of sampling heads at different positions to sample one by one, the clamping member is used to clamp the transposition member and the driving component (4), and the anti-slipping positioning member is used to prevent the transposition member from sliding down due to gravity; The position-changing member comprises a mounting frame (31), a motor (32) is fixed below the mounting frame (31), a mounting plate (33) is rotatably disposed below the mounting frame (31), an annular groove (34) is disposed on the top of the mounting plate (33), a plurality of clamping grooves (35) are disposed on the outer side of the mounting plate (33), the clamping grooves (35) are communicated with the annular grooves (34), and a double-slot clamping frame (36) is disposed inside the clamping grooves (35).

2. The high-efficiency liquid-based cell staining machine according to claim 1, characterized in that: The clamping member comprises a spring (37), a clamping column (38) and a positioning block (39); one end of the spring (37) is fixed inside the double-slot clamping frame (36); the other end of the spring (37) is fixedly connected to the clamping column (38); two clamping grooves (310) are formed on the outer surface of the positioning block (39), and the positioning block (39) slides on the inner side of the double-slot clamping frame (36).

3. The high-efficiency liquid-based cell staining machine according to claim 2, characterized in that: The anti-drop positioning member comprises an L-shaped plate (311) and a plurality of rubber positioning strips (312); the L-shaped plate (311) is fixed below the double-slot clamping frame (36); the rubber positioning strips (312) are fixed to the outer surface of the L-shaped plate (311); a plurality of connecting grooves (313) are provided inside the mounting plate (33); and the L-shaped plate (311) slides inside the connecting grooves (313).

4. The high-efficiency liquid-based cell staining machine according to claim 2, characterized in that: The driving assembly (4) comprises an X-axis driving mechanism (41) fixed inside the dyeing chamber (1), a Z-axis driving mechanism (42) is installed below the X-axis driving mechanism (41), and a Y-axis driving mechanism (43) is installed on one side of the Z-axis driving mechanism (42).

5. The high-efficiency liquid-based cell staining machine according to claim 4, characterized in that: The mounting frame (31) is fixed to the outer surface of the Y-axis driving mechanism (43).

6. The high-efficiency liquid-based cell staining machine according to claim 4, characterized in that: The positioning block (39) is fixed to one end of the telescopic rod of the Y-axis driving mechanism (43).

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