Kit for detecting vascular endothelial injury marker

Abstract

The utility model relates to the technical field of in vitro diagnostic reagents, in particular to a kit for detecting vascular endothelial injury markers, which comprises a kit body, a placement bin is arranged in the kit body in a left-right penetrating manner, and a sample port and a sampling port which are communicated with the placement bin are respectively arranged at two ends of the outer wall of the kit body; an opening is formed in one side of the sample bin, the opening of the sample bin corresponds to the sampling opening, and the sample bin is placed in the placing bin in a sliding mode; the kit comprises a placement bin, a sliding plate, the sliding plate is slidably mounted in the placement bin, a placement plate for clamping test paper is integrally formed at the upper end of the sliding plate, and the two ends of the sliding plate are elastically connected with abutting plates through elastic pieces. The defect that in the prior art, an open structure is extremely prone to being polluted is overcome.

Description

Technical Field

[0001] The utility model relates to the technical field of in vitro diagnostic reagents, and particularly relates to a kit for detecting vascular endothelial injury markers. Background Art

[0002] Existing kits for vascular endothelial markers, such as an immunofluorescence kit for quantitatively detecting vascular endothelial marker CD146 proposed in Chinese Patent Application No. "CN201821365556.0". This immunofluorescence kit adopts quantum dot labeling technology and modifies quantum dots with thioglycolic acid to ensure the stability of quantum dot-labeled antibodies. It has the advantages of high detection result sensitivity, short detection time, and good specificity. The kit of the utility model is delicate, light, and easy to carry, has no rigid requirements for the operation site and environment, is simple and fast to operate, has simple detection steps, and has a quantitative detection function;

[0003] For existing kits of this type of vascular endothelial marker, their main body is of an open structure. Especially, the jack (the structure name in the above-mentioned prior art example) part is extremely vulnerable to contamination, resulting in deviation of the measurement results;

[0004] Therefore, this case will propose a new kit for vascular endothelial markers to solve the problem of easy contamination caused by its open structure. Summary of the Utility Model

[0005] The purpose of the utility model is to provide a kit for detecting vascular endothelial injury markers to solve the disadvantages such as extremely easy contamination in the prior art with an open structure.

[0006] To achieve the above purpose, the utility model adopts the following technical solutions:

[0007] Design a kit for detecting vascular endothelial injury markers, including:

[0008] A box body, with a placement bin penetrating through the left and right inside the box body, and a sample port and a sampling port communicating with the placement bin are respectively opened at both ends of the outer wall of the box body;

[0009] A sample bin, with one side of the sample bin open, and the opening of the sample bin is correspondingly arranged with the sampling port. The sample bin is slidably placed inside the placement bin;

[0010] A sliding plate, which is slidably installed inside the placement bin. A placement plate for clamping test strips is integrally formed at the upper end of the sliding plate. Both ends of the sliding plate are elastically connected with abutting plates through elastic members, and the two groups of abutting plates are respectively in sliding abutment with the end faces on both sides inside the box body.

[0011] Preferably, a positioning sliding groove is formed through one end face of the box body, a rotating frame extending to the outside of the box body through the positioning sliding groove is integrally formed on the outer wall of the sample chamber, a clamping frame is rotatably installed at the outer end of the rotating frame, and one end of the clamping frame is movably clamped with the outer wall of the box body.

[0012] Preferably, a plurality of groups of positioning slots for cooperating with the clamping frame are formed on the outer walls of the box body on the left and right sides of the positioning sliding groove.

[0013] Preferably, soft pads are sleeved at the openings on the left and right sides of the positioning sliding groove, and the soft pads are in sliding contact with the rotating frame.

[0014] Preferably, the width of the box body is three times the width of the sample chamber, the left side of the box body is a sample filling area, the middle of the box body is a sealed static area, and the right side of the box body is a taking-out area.

[0015] Preferably, the area where the sample port is located is the filling area, and the position where the sampling port is located is the taking-out area.

[0016] Preferably, an observation window is formed on the outer wall of the box body, and the observation window is formed on one side of the sample port.

[0017] Preferably, a plurality of groups of functional ports are formed on the outer end face of the sample chamber.

[0018] Preferably, a placement slideway is formed inside the sample chamber, sliding wheels are installed at both the left and right ends of the sliding plate, and the sliding wheels can slide in the placement slideway.

[0019] A kit for detecting vascular endothelial injury markers proposed by the present utility model has the beneficial effects that:

[0020] Through the combined structure of the box body and the sample chamber provided, the test paper in the sample chamber can be in a relatively sealed environment when waiting for the result, reducing possible external contamination, improving the detection accuracy and reducing the environmental requirements;

[0021] Through the provided sliding plate, the test paper can be taken separately so as to be better detected by being placed in an external observation device. At the same time, it also enables components such as the box body, the sample chamber, and the sliding plate to be reused after cleaning, reducing the material cost. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 A three-dimensional structural schematic diagram with... as the main body;

[0023] Figure 2 A lateral sectional structural schematic diagram with... as the main body;

[0024] Figure 3Explosion disassembly structure schematic diagram with the main body;

[0025] Figure 4 Multi-view structure schematic diagram of the sample chamber;

[0026] Figure 5 Multi-view structure schematic diagram of the sliding plate;

[0027] Figure 6 Multi-view structure schematic diagram of the box body.

[0028] In the figure:

[0029] 1. Box body; 101. Placing bin; 102. Sample port; 103. Sampling port; 104. Observation window; 105. Positioning sliding groove; 1051. Positioning slot; 1052. Soft pad;

[0030] 2. Sample chamber; 201. Placing slideway; 202. Function port; 203. Rotating frame; 204. Clamping frame;

[0031] 3. Sliding plate; 301. Placing plate; 302. Elastic member; 303. Abutting plate; 304. Sliding wheel;

[0032] 4. Sample bottle. Specific implementation mode

[0033] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments.

[0034] Refer to Figure 1-6 , here is an example of the implementation mode of the main body:

[0035] A kit for detecting vascular endothelial injury markers, refer to Figure 6 , including a box body 1. A placing bin 101 is penetrated through the left and right inside the box body 1. A sample port 102 and a sampling port 103 communicating with the placing bin 101 are respectively opened at both ends of the outer wall of the box body 1. The sample port 102 is used to install and place the sample bottle 4, and the sampling port 103 is used to take out the test strip. A sample chamber 2 with one side open is slidably placed inside the placing bin 101. The opening of the sample chamber 2 is arranged in cooperation with the sampling port 103. A sliding plate 3 is slidably installed inside the placing bin 101. A placing plate 301 for clamping the test strip is integrally formed at the upper end of the sliding plate 3. Elastic members 302 are elastically connected to abutting plates 303 at both ends of the sliding plate 3. Refer to Figure 2 , and the two groups of abutting plates 303 are respectively slidably abutted against the end faces on both sides inside the box body 1;

[0036] Based on the above content, the sample bin 2 can slide inside the box body 1, so that after the sample is injected into the sample bin 2, it can move to a relatively enclosed environment to prevent its filling port from being contaminated; the detachable structure between the placement plate 301 and the test strip also enables components such as the sliding plate 3 to be reused after cleaning, reducing costs;

[0037] Furthermore, the width of the box body 1 should be at least three times the width of the sample bin 2, so that there are at least three different functional areas for the sample bin 2 inside the box body 1. Refer to Figure 1 , which may include a sample filling area on the left, a sealed static area in the middle, and a removal area on the right;

[0038] Even further, the area where the sample port 102 is located is the filling area, and the position where the sampling port 103 is located is the removal area. When the sample bin 2 is pushed to the removal area, the elastic member 302 can push the abutting plate 303 at the outer end to extend out of the sampling port 103;

[0039] Furthermore, a transparent observation window 104 is provided on the outer wall of the box body 1, and the observation window 104 is provided on one side of the sample port 102;

[0040] Furthermore, multiple groups of functional ports 202 are provided on the outer end face of the sample bin 2, and these functional ports 202 are the same as those of the existing test kits, and are respectively used for sample filling and observing the label status;

[0041] Furthermore, a placement slideway 201 is provided inside the sample bin 2, and sliding wheels 304 are installed at both the left and right ends of the sliding plate 3, so that the sliding wheels 304 can slide inside the placement slideway 201, improving the stability of the sliding plate 3 and its combination.

[0042] Refer to Figure 2 、 3 、4, 6, here are examples of the implementation methods for positioning the box body 1 and the sample bin 2:

[0043] A positioning chute 105 is provided through the end face on one side of the box body 1. A rotating frame 203 that passes through the positioning chute 105 and extends to the outside of the box body 1 is integrally formed on the outer wall of the sample bin 2. A clamping frame 204 is rotatably installed at the outer end of the rotating frame 203, and one end of the clamping frame 204 is movably clamped with the outer wall of the box body 1;

[0044] Based on the above content, through the provided clamping frame 204, the position of the sample bin 2 inside the box body 1 can be positioned, playing a fixing role and preventing the sample bin 2 from freely sliding inside the box body 1; the open structure of the positioning chute 105 enables the disassembly and assembly between the box body 1 and the sample bin 2;

[0045] Furthermore, multiple groups of positioning slots 1051 for cooperating with the clamping frame 204 are provided on the outer wall of the box body 1 on the left and right sides of the positioning chute 105;

[0046] Furthermore, soft pads 1052 are sleeved on the openings on both sides of the positioning slot 105 , so that the rotating frame 203 will be subjected to a certain sliding abutment resistance when it leaves the positioning slot 105 .

[0047] Last addition:

[0048] The specification of the sample port 102 can be adapted to the output port of the sample tube or the syringe, and the two can be directly connected seamlessly to avoid contamination;

[0049] refer to Figure 3 One side of the clamping frame 204 is provided with a tooth that matches the positioning slot 1051. When the other side is pressed, the side with the tooth is tilted up to unlock.

[0050] Based on the above-mentioned embodiments, when assembling:

[0051] Place the test paper on the placement plate 301, send the sliding plate 3 into the sample chamber 2, and make the sliding wheel 304 slide into the placement slide 201; press the abutment plate 303 located on the outside to retract it into the sample chamber 2, send the sample chamber 2 and the sliding plate 3 assembly into the placement chamber 101 of the box body 1, and make the functional port 202 opened on the sample chamber 2 align with the sample port 102, and the assembly is completed at this time.

[0052] Based on the above implementation examples, when used:

[0053] Connect the sample bottle 4 to the sample port 102, and send the sample liquid in the sample bottle 4 into the sample port 102. When the injection is completed, press down the clamping frame 204 and push it to move the sample chamber 2 to the middle of the box body 1 to wait. When the conditions are met, press down the clamping frame 204 again and push it to move the sample chamber 2 to the right side of the box body 1. At this time, the sliding plate 3 can be taken out through the sampling port 103.

[0054] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A kit for detecting vascular endothelial injury markers, characterized in that: include: A box body (1), wherein a storage chamber (101) is provided in the box body (1) on the left and right sides, and a sample port (102) and a sampling port (103) are provided at two ends of an outer wall of the box body (1) and are communicated with the storage chamber (101); A sample chamber (2), one side of the sample chamber (2) is open, the opening of the sample chamber (2) is arranged corresponding to the sampling port (103), and the sample chamber (2) is slidably placed inside the placement chamber (101); A sliding plate (3), the sliding plate (3) being slidably mounted inside the placement chamber (101), the upper end of the sliding plate (3) being integrally formed with a placement plate (301) for clamping the test paper, both ends of the sliding plate (3) being elastically connected to abutment plates (303) via elastic members (302), and two groups of abutment plates (303) being slidably abutted against end surfaces on both sides of the interior of the box body (1), respectively.

2. A kit for detecting vascular endothelial injury markers according to claim 1, characterized in that: A positioning slot (105) is formed through one end surface of one side of the box body (1); the outer wall of the sample chamber (2) is integrally formed with a rotating frame (203) that passes through the positioning slot (105) and extends to the outside of the box body (1); a clamping frame (204) is rotatably mounted on one end of the outer side of the rotating frame (203); one end of the clamping frame (204) is movably clamped to the outer wall of the box body (1).

3. A kit for detecting vascular endothelial injury markers according to claim 2, characterized in that: The outer wall of the box body (1) located on the left and right sides of the positioning slide groove (105) is provided with a plurality of groups of positioning slots (1051) for cooperating with the clamping frame (204).

4. A kit for detecting vascular endothelial injury markers according to claim 2, characterized in that: Soft pads (1052) are sleeved on the openings on the left and right sides of the positioning slide groove (105), and the soft pads (1052) are in sliding contact with the rotating frame (203).

5. A kit for detecting vascular endothelial injury markers according to claim 1, characterized in that: The width of the box body (1) is three times the width of the sample chamber (2); the left side of the box body (1) is a sample filling area, the middle of the box body (1) is a sealed static area, and the right side of the box body (1) is a removal area.

6. A kit for detecting vascular endothelial injury markers according to claim 5, characterized in that: The area where the sample port (102) is located is the filling area, and the area where the sampling port (103) is located is the removal area.

7. A kit for detecting vascular endothelial injury markers according to claim 1, characterized in that: An observation window (104) is provided on the outer wall of the box body (1), and the observation window (104) is provided on one side of the sample port (102).

8. A kit for detecting vascular endothelial injury markers according to claim 1, characterized in that: The outer end surface of the sample chamber (2) is provided with multiple groups of functional ports (202).

9. A kit for detecting vascular endothelial injury markers according to claim 1, characterized in that: A placement slideway (201) is provided inside the sample chamber (2), and sliding wheels (304) are installed at both left and right ends of the sliding plate (3), and the sliding wheels (304) can slide in the placement slideway (201).

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