Device for detecting component and / or content in sample

Abstract

A device for detecting a component and / or content in a sample, comprising: a sample holding part (100) comprising two holding surfaces (110) such that the sample to be detected can be held between the two holding surfaces (110) opposite to each other by being limited by surface tension; a detection light source (200) that emits detection light such that the sample can be excited to emit fluorescent light and at least a portion of the fluorescent light can be received at one of the holding surfaces (110); and a first light blocking structure (300), the first light blocking structure (300) at least partially circumferentially surrounding the sample to be detected, so as to reduce the influence on the detection.

Description

Technical Field

[0001] The utility model relates to the field of material analysis and detection, specifically to equipment for optical micro-detection, and more specifically to a device for detecting components and content in a sample or for detecting both, such as a micro-spectrophotometer. Background Art

[0002] Common series products of micro-spectrophotometers generally establish a micro-liquid optical channel by maintaining a liquid column between the surfaces of two optical fiber heads, and measure the absorbance and / or fluorescence of a liquid sample by emitting light into the optical channel.

[0003] With the current improvement in the accuracy requirements for detection and analysis results, in existing detection and analysis devices, it is increasingly found that there is a certain degree of instability in absorbance and / or fluorescence detection tests, especially in fluorescence detection tests, such as during calibration detection. This undesired instability makes the existing detection and analysis devices unable to meet the increasing accuracy requirements for detection and analysis, resulting in a significant reduction in the reliability of detection results.

[0004] To address the above problems, those skilled in the art in the prior art generally consider improving the stability and consistency of detection results by enhancing the luminous performance of the light source for detection and the performance of the optical sensor for receiving and outputting light, as well as adjusting the detection and analysis algorithms. On the one hand, the research and development costs for the transformation and upgrading of such optical components and analysis and detection algorithms are relatively high. On the other hand, current technical practices increasingly show that the detection results of the transformed detection and analysis devices still cannot achieve the desired stability and consistency in different detection environments.

[0005] During the actual test process, it may be necessary to perform image analysis on the maintained liquid column to be measured. To perform this image analysis on the liquid sample, a camera can be used to analyze the image of the liquid sample column. The liquid sample image analysis generally may include, but is not limited to, bubble morphology detection, detection of breakage, skew, or vacancy of the liquid column, etc.

[0006] In existing measurement devices, the holding surfaces of the two optical fiber heads for holding the liquid column are generally arranged openly in the test environment, and the test results of these detection devices are difficult to meet the requirements for analysis accuracy as described above. Summary of the Utility Model

[0007] The utility model provides a device for detecting components and / or content in a sample, including:

[0008] A sample holding part, the sample holding part includes two holding surfaces, so that the sample to be detected can be restricted by surface tension and held between the two opposite holding surfaces;

[0009] A light source for detection, the light source for detection emits detection light so that the sample can be excited to emit fluorescence, and at least a part of the fluorescence can be received at one of the holding surfaces;

[0010] A first light-shielding structure, the first light-shielding structure at least partially circumferentially surrounds the sample to be detected to reduce the influence on the detection.

[0011] By the arrangement of the first light-shielding structure, the detection device of the present invention can obtain a stable detection optical environment at the sample through simple structural transformation of the device. This stable detection optical environment can, on the one hand, reduce the influence of external ambient light on the optical signal at the sample, and on the other hand, can provide a relatively stable background light environment for the required image analysis, and also helps to reduce the irradiation or interference of the light source for fluorescence detection itself or the fluorescence excited by it on the sample to be measured to the instrument operator.

[0012] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample of the present invention, the first light-shielding structure is fixedly arranged relative to one of the two holding surfaces.

[0013] The first light-shielding structure fixedly arranged in this way is convenient for installation and can better adapt to the inherent shape of the original detection device and the operating habits of the experimenter.

[0014] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample of the present invention, the device includes a base and a movable arm, and the two holding surfaces are respectively fixed on the base and the movable arm,

[0015] wherein, the first light-shielding structure is fixedly arranged relative to the movable arm,

[0016] and wherein, the movable arm can move relative to the base so that the device can be switched between an open position and a closed position. In the closed position, the two holding surfaces face each other to hold the sample by surface tension, and the first light-shielding structure can reduce the influence on the detection in the closed position. In the open position, the first light-shielding structure moves to a position farther from the base relative to the closed position.

[0017] The movement of the movable arm relative to the base is convenient for placing the sample to be detected in the open position, and plays the role of the first light-shielding structure in the closed position. The switching operation between the two positions is convenient for the operator, and for the mechanical structure, the desired detection function is realized through a simple state switching mechanism.

[0018] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample according to the present utility model, the first light shielding structure includes a housing in a U shape in the circumferential direction, and the device further includes a matching structure that faces the U-shaped opening of the housing and at least partially surrounds the sample in the circumferential direction to cooperate with the housing to jointly form an enclosed internal space.

[0019] The light shielding component in the shape of a U-shaped housing can provide a more perfect light shielding effect, which can avoid the interference of the light source for fluorescence detection and / or the fluorescence excited by it to the test operators from various directions, and is also helpful to prevent the interference of the ambient light changes from various directions to the background light environment during image analysis. In particular, by providing a matching structure that matches the opening of the U-shaped housing, it is beneficial to further improve the light shielding effect at the horizontal height of the U-shaped housing, and the cooperation between the two can also ensure the optical cooperation relationship between the test light source and the sample to be measured.

[0020] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample according to the present utility model, the device further includes: a supplementary light source, which is arranged on the matching structure and is configured to illuminate the enclosed internal space in the closed position.

[0021] The setting of the supplementary light source is beneficial to compensating for the defect that the light intensity of the background light environment may be too weak due to the setting of the first light shielding structure and it is difficult to meet the light intensity requirements for image analysis.

[0022] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample according to the present utility model, the device further includes: a photographic device configured to photograph the sample, and the photographic device is arranged on the matching structure, wherein the photographic device and the supplementary light source are arranged to be spaced apart by a supplementary light angle in the circumferential direction around the sample.

[0023] The photographic device and the supplementary light source spaced apart from each other in the circumferential direction are beneficial to reducing the unwanted shadows generated by the supplementary light source itself around the image analysis object.

[0024] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample according to the present utility model, the supplementary light angle is 35 degrees to 65 degrees.

[0025] The preferred range of this supplementary light angle is beneficial to achieving the desired lighting effect.

[0026] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample according to the present utility model, the supplementary light angle is 44 degrees to 56 degrees.

[0027] The preferred range of the supplementary light angle is conducive to realizing the mechanical fit between the mating structure 310 and the U-shaped housing.

[0028] According to a preferred but non-limiting embodiment of the device for detecting components and / or content in a sample of the present invention, the supplementary light angle is 50 degrees.

[0029] The preferred range of the supplementary light angle is conducive to achieving stronger applicability and better supplementary light effect.

[0030] According to a preferred but non-limiting embodiment of the device for detecting components and / or content in a sample of the present invention, it includes:

[0031] An output optical fiber, the output optical fiber includes a receiving end and an output end, the receiving end is optically connected to one of the two holding surfaces to transmit the light from the sample to the output end via the receiving end;

[0032] An output end mounting bracket, the output end of the output optical fiber is mounted at the output side surface of the output end mounting bracket; and

[0033] A sensing element mounting bracket, the sensing element mounting bracket is configured to mount an optical signal sensing element and includes a receiving side surface arranged facing the output side surface, the optical signal sensing element is configured to receive the output light output by the output end,

[0034] Wherein,

[0035] The second light shielding structure includes a first part, the first part is provided on at least one of the output side surface and the receiving side surface, and the shape of the first part is configured to reduce the light rays introduced between the output side surface and the receiving side surface into the output optical path between the output end and the optical signal sensing element.

[0036] The second light shielding structure can further reduce the influence of ambient light on the output side optical path and the output optical signal transmitted therein. The first part of the second light shielding structure arranged in this way can improve and reduce the adverse influence of ambient light on the output light in the possible light leakage gap between the output end mounting bracket and the sensing element mounting bracket, which are two separate components.

[0037] According to a preferred but non-limiting embodiment of the device for detecting components and / or content in a sample of the present invention, it is characterized in that,

[0038] The output end mounting bracket and the sensing element mounting bracket are capable of relative movement with respect to each other in a sensing element switching direction perpendicular to the optical axis direction of the output light of the output end. The first part of the second light blocking structure includes a first light blocking portion on the output side surface of the output end mounting bracket and a second light blocking portion on the receiving side surface of the sensing element mounting bracket. The first light blocking portion and the second light blocking portion are staggered from each other in the optical axis direction of the output light and are spaced apart from each other in the sensing element switching direction.

[0039] The second light blocking structure arranged in this way, on the one hand, further reduces the adverse influence of ambient light on the output light in the light leakage gap between the output end mounting bracket and the sensing element mounting bracket through the staggered light blocking portions, and also ensures the possibility of relative movement between the output end mounting bracket and the sensing element mounting bracket.

[0040] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample of the present invention, the first light blocking portion includes bumps protruding towards the sensing element mounting bracket at both ends of the output side surface in the sensing element switching direction, and the second light blocking portion includes grooves on the receiving side surface, and the bumps are received in the grooves.

[0041] And / or,

[0042] The first light blocking portion includes a guide rail extending along the sensing element switching direction, and the second light blocking portion includes a guiding portion that is shape-matched with the guide rail to allow the guiding portion to move along the guide rail.

[0043] Forming the first part of the second light blocking structure through the bumps and grooves and the guide rail and the guiding portion can make the structures and molding of both the output end mounting bracket and the sensing element mounting bracket simpler.

[0044] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample of the present invention, the optical signal sensing element is mounted in the sensing element mounting bracket through a circuit board fixed thereto, and there is a circuit board gap between the circuit board and the sensing element mounting bracket.

[0045] Wherein, the second light blocking structure includes a second part, and the second part includes a light blocking material piece with pores disposed in the circuit board gap around the optical signal sensing element.

[0046] The second part of the second light blocking structure arranged in this way can reduce the adverse influence of ambient light on the output light in the mounting gap on the side of the optical signal sensing element close to the circuit board.

[0047] According to a preferred but non-limiting embodiment of the device for detecting components and / or contents in a sample of the present utility model, the optical signal sensing element is mounted in the sensing element mounting frame through a circuit board fixed thereto. The second light-blocking structure includes a third part, and the third part includes a light-blocking cover member. The light-blocking cover member is located on the side of the circuit board facing away from the output optical fiber and can at least partially block ambient light from this side.

[0048] The third part of the second light-blocking structure arranged in this way can reduce the adverse effect of ambient light on the output light on the side of the circuit board facing away from the optical signal sensing element. BRIEF DESCRIPTION OF THE DRAWINGS

[0049] This document includes drawings to provide further understanding of various embodiments. The drawings are incorporated into and constitute a part of this specification.

[0050] The drawings illustrate various embodiments described herein and, together with the written description, are used to explain the principles and operations of the claimed subject matter.

[0051] With reference to the above objectives, the technical features of the present utility model are clearly described below, and its advantages are obvious from the following detailed description with reference to the drawings. The drawings illustrate, by way of example, the preferred embodiments of the present utility model without limiting the scope of the present utility model.

[0052] In the drawings:

[0053] Figure 1 is a perspective schematic view of the structure near the sample holding part of a preferred embodiment of the device for detecting components and / or contents in a sample according to the present utility model. Among them, the device is in an open position to better show the specific structure inside the device.

[0054] Figure 2 is Figure 1 a perspective schematic view of the structure near the sample holding part of the device for detecting components and / or contents in a sample according to the present utility model shown in

[0055] Figure 3 is a top view showing Figure 1 and Figure 2 the device for detecting components and / or contents in a sample according to the present utility model in . Among them, in order to schematically show clearly the relative positional relationship among the supplementary light source, the photographic device, and the holding surface, other structural components of the device are removed.

[0056] Figure 4 is a perspective exploded view of the optical signal output part of a preferred embodiment of the device for detecting components and / or contents in a sample according to the present utility model.

[0057] Figure 5 Is Figure 4 A cross-sectional view of the optical signal output part of the preferred embodiment of the device for detecting components and / or content in a sample shown in

[0058] Figure 6 Is Figure 4 A cross-sectional view of the optical signal output part of the preferred embodiment of the device for detecting components and / or content in a sample shown in Figure 4 along a section parallel to the plane in which the axes of the two output optical fibers are located and perpendicular to the section in

[0059] Figure 7 Is Figure 4 A three-dimensional schematic view of the output terminal mounting bracket of the optical signal output part of the preferred embodiment of the device for detecting components and / or content in a sample shown in

[0060] Figure 8 Is Figure 4 A three-dimensional schematic view of the sensing element mounting bracket of the optical signal output part of the preferred embodiment of the device for detecting components and / or content in a sample shown in

[0061] Figure 9 Is from the opposite angle of Figure 4 A three-dimensional exploded schematic view of the optical signal output part of the preferred embodiment of the device for detecting components and / or content in a sample according to the present invention shown in

[0062] List of reference numerals

[0063] 100 Sample holding part

[0064] 110 Holding surface

[0065] 111 Base

[0066] 112 Movable arm

[0067] 200 Light source for detection

[0068] 300 First light-blocking structure

[0069] 310 Matching structure

[0070] 400 Supplementary light source

[0071] 500 Output optical fiber

[0072] 510 Output end

[0073] 520 Output terminal mounting bracket

[0074] 521 Bump

[0075] 522 Guide Rail

[0076] 523 Output Side Surface

[0077] 524 Photoelectric Position Sensor

[0078] 600 Optical Signal Sensing Element

[0079] 610 Sensing Element Mounting Bracket

[0080] 611 Groove

[0081] 612 Guide Portion

[0082] 613 Receiving Side Surface

[0083] 620 Circuit Board

[0084] 700 Light Shielding Material Part

[0085] 800 Light Shield Cover Part

[0086] 900 Photographic Equipment

[0087] α Fill Light Angle

[0088] M Motor Detailed Embodiments

[0089] Now, the embodiments of the present invention will be described in detail. Examples of these embodiments are shown in the drawings and will be described below.

[0090] Although the present invention will be described in conjunction with exemplary embodiments, it should be understood that this specification is not intended to limit the present invention to those exemplary embodiments. On the contrary, the present invention is intended to cover not only these exemplary embodiments but also various alternative forms, modifications, equivalent forms, and other embodiments that may be included within the spirit and scope of the present invention.

[0091] For the purpose of facilitating the explanation and precise definition of the technical solutions of the present invention, the terms "upper", "lower", "inner", and "outer" are used to describe the features with reference to the positions of the features of the exemplary embodiments shown in the drawings.

[0092] First, some of the technical terms involved in this document are defined.

[0093] In this document, "circumferential direction" refers to the direction around the central axis or around the center point in the same plane. The specific paths of the circumferential direction include, but are not limited to, circular paths, elliptical paths, oval paths, polygonal paths, or other irregular paths.

[0094] As used herein, "surrounding" means that the corresponding object bends or folds at least partially in the circumferential direction around a central axis or around a center point in the same plane to form a loop at least partially. Herein, bending and folding mean that there is at least partial curvature in a plane orthogonal to the central axis or in the plane of the center point such that the relevant object presents at least one segment of an annular member having various different shapes around the central axis or the center point. The annular member includes, but is not limited to, circular rings, square rings, other polygonal rings, and irregularly shaped rings.

[0095] As used herein, "optical axis" means the center line of a light beam or light column, and when the light beam is in a scattered state, it means the center line of the light beam or light column in the main direction.

[0096] In view of the deficiencies in the accuracy of detection and analysis in the prior art, the present utility model creatively comes up with the idea of paying attention to the background light intensity of the above-mentioned image analysis. After analysis, it is found that the background light intensity depends on the ambient light in the test site, including indoor ambient light and outdoor ambient light. Various common ambient light differences, such as light intensity, shadows, chromaticity, etc., may affect image analysis and even prevent the required image analysis from being carried out at all, thereby interfering with and hindering the progress of the test.

[0097] On the other hand, in order to enable the measuring device to carry more test functions, the present utility model also studies how to meet the requirement of simultaneously detecting the absorbance and fluorescence of the same trace sample to be measured at the same sample position. In the above-mentioned open fiber head holding position, the fluorescence detection light source is generally also arranged in an open position without obstacles blocking it, and the detection light emitted by it will interfere with the operation of the operator.

[0098] In this regard, the present utility model also notices the problems commonly reported by operators. Sometimes, it is not the direct irradiation of the detection fluorescence light source that infects the operator's vision with light, but the fluorescence of various wavelengths excited by the sample to be measured irradiated by the fluorescence light source that affects the observation of the operator or other observation devices.

[0099] On the other hand, during the development process of the present utility model, it is also found through analysis that the output-side optical fiber may be affected by external ambient light during the process of being transmitted from the output-side fiber head to the output end and then reaching the photosensitive element arranged at the output end. These ambient lights often have an adverse effect on the measurement accuracy, especially on the measurement accuracy of low-concentration samples. Therefore, it is necessary to study the sources and preventive measures of the ambient light at the output end and reduce the undesired interference of the ambient light at this position on the output signal. In particular, while meeting the requirement of reducing the undesired interference of the ambient light, the relative movement of some moving parts in the output area should also be allowed.

[0100] The various preferred but non-limiting embodiments of the present utility model will be specifically described below with reference to the accompanying drawings.

[0101] First, refer to Figures 1 to 3 to specifically describe the specific structure near the sample holding part 100 of the device for detecting components and / or contents in a sample according to a preferred embodiment of the present utility model.

[0102] According to Figure 1 (showing the open position of the device) and Figure 2 (showing the closed position of the device), the preferred embodiment of the present device includes a sample holding part 100, a detection light source 200, and a first light blocking structure 300. The detection light source 200 is used for detecting the type of components of the sample to be measured, the content of the corresponding type of components, or both.

[0103] The sample holding part 100 includes at least two holding surfaces 110.

[0104] Specifically, Figure 1 one of the holding surfaces 110 located below can be seen and marked in Figure 2 . It can be understood that the device further includes another holding surface 110 located above. When the device is in the closed position shown in

[0105] , the other holding surface 110 is opposite to the lower holding surface 110 so that the sample to be detected (not shown in the figure) can be restricted by surface tension and held between the two opposite holding surfaces 110.

[0106] It should be noted here that the specific shape of the holding surface 110 can be circular as shown in the figure, but it can also be in various other common shapes. It should also be noted that the holding surface 110 can be respectively provided with optical fiber heads at the center for conducting light.

[0106] In the preferred embodiment shown in Figure 1 and Figure 2 , the device preferably includes a base 111 and a movable arm 112.

[0107] Those skilled in the art can understand that the movable arm 112 can be directly or indirectly connected to the base 111 in various common ways, such as hinged connection or form-fit connection, to achieve relative movement between the base 111 and the movable arm 112.

[0108] It should also be noted that although in the preferred embodiment in the figure, the movable arm 112 and the base 111 are shown to be connected to each other at the distal position in the figure, however, the connection position of the two is not limited to this, but as long as the movable arm 112 can move relative to the base 111.

[0109] In the above case including the base 111 and the movable arm 112, the two holding surfaces 110 are respectively fixed on the base 111 and the movable arm 112. Preferably, the movable arm 112 is movable relative to the base 111 so that the device can be in, for example, Figure 1 the open position shown in Figure 2 and the closed position shown in

[0110] switch between them. More preferably, the base 111 and the movable arm 112 are configured to be respectively held in the above open position and closed position to respectively meet the requirements of dispensing the sample to be tested and detecting and analyzing. Those skilled in the art can select various common mechanical structures in the art to achieve the above positioning and holding functions, which will not be elaborated here. Figure 1 and Figure 2 Regarding the specific structures of the base 111 and the movable arm 112, it should be noted that the specific structures and shapes of the base 111 and the movable arm 112 shown in

[0111] are only for illustration and are not intended to limit the protection scope of the present utility model. For example, the base 111 shown in the figure may include a first horizontal step surface for setting the holding surface 110 and a vertical step surface for setting the detection-related devices described below. And, a protruding rib for easy gripping may be provided at the top of the movable arm 112 shown in the figure. However, the specific structures of the base 111 and the movable arm 112 of the present utility model are not limited thereto, but may also cover various other structures that can meet the corresponding detection test requirements, which will not be elaborated here.

[0112] The detection light source 200 emits detection light so that the sample can be excited to emit fluorescence, and at least a part of the fluorescence can be received at one of the holding surfaces 110. Those skilled in the art can understand that generally, the detection light source 200 can emit the above detection light for exciting fluorescence towards the sample to be tested, but the detection light source 200 can also emit the detection light in various directions as long as it can excite the desired fluorescence on the sample to be tested. Figure 1 For example but not limited to, like the two detection light sources 200 shown in

[0113] the detection light source 200 of the present utility model may include a first detection light source with a wavelength of 470 nm and a second detection light source with a wavelength of 630 nm. Fluorescence detection light sources with different wavelengths can meet more different fluorescence detection requirements.

[0114] The first light-shielding structure 300 at least partially circumferentially surrounds the sample to be detected to reduce the influence on the detection. It should be noted here that the so-called reduction of the influence on the detection in this article means reducing or avoiding the influence on each participating element in the entire detection process and the obtained detection and analysis results, for example, including but not limited to, reducing the escape of various lights involved in the detection process to the surrounding environment and the relevant test participants, reducing the amount and intensity of external ambient light reaching the sample to be detected and / or the above-mentioned detection light, providing a more stable detection optical environment, and so on.

[0115] As Figure 1 and Figure 2 In the preferred embodiment shown in

[0116] In Figure 1 and Figure 2 the preferred embodiment of

[0117] the first light-shielding structure 300 may include a housing that is U-shaped in the circumferential direction or other circumferentially open or closed shapes. The U-shape here refers to a circumferential angle that is no more than 90° open in the circumferential direction around the vertical axis passing through the sample, and is not intended to limit the circumferential surrounding path of the housing. The housing may include three planar portions that are arranged approximately successively at 90° in the circumferential direction and smooth transition portions between the three planar portions as shown in the figure, or may not include planar portions but only curved surface portions.

[0118] It should also be noted that the specific form of the first light-shielding structure 300 is not limited to this, but may also include various other shapes of structures that can reduce the influence on the detection. For example, by way of example but not limitation, the first light-shielding structure 300 may include a light-blocking block that is thicker than the housing structure shown in the figure, or the first light-shielding structure 300 may include a plurality of mutually separated light-blocking housing pieces (in this case, a light-transmitting gap may be left between the respective light-blocking housing pieces), or the first light-shielding structure 300 may be provided with multiple layers of light-blocking housings for blocking lights of different wavelengths in the radial direction (i.e., the direction towards or away from the sample) or the circumferential direction, or the first light-shielding structure 300 may include a housing that is at least partially circular.

[0119] Finally, it should be noted that although the U-shaped opening shown in the figure faces the distal end, the orientation of the U-shaped opening is not limited to this, but may also face any other direction in the circumferential direction.

[0120] In Figure 2 the closed position shown, the first light-shielding structure 300 can reduce the influence on detection in the closed position. In Figure 1 the open position shown, the first light-shielding structure 300 can move to a position farther from the base 111 relative to the closed position, that is, a position where the two holding surfaces 110 are farther apart from each other than in the closed position.

[0121] The device shown in the figure may further include a mating structure 310. For details, reference may be made to Figure 1 , the mating structure 310 can face the U-shaped opening of the housing and at least partially surround the sample circumferentially to cooperate with the housing to jointly form an enclosed internal space.

[0122] It should be noted that although Figure 1 the mating structure 310 shown is formed by the vertical surface of the stepped portion of the base 111, however, the mating structure 310 can also be formed as a part of the movable arm 112 or a part that can be detachably coupled to the base 111 or the movable arm 112 of the device.

[0123] It should also be noted that the mating structure 310 can, but does not have to, closely enclose the housing circumferentially, but as long as it can occupy the opening section of the housing circumferentially. In other words, the so-called enclosed internal space herein does not require the obtained space to be completely isolated from the outside, but only requires that the optical communication with the outside is limited.

[0124] Finally, the applicant hereby emphasizes again that the above-mentioned light source 200 for detection is disposed on the mating structure 310 in the illustrated preferred embodiment. However, those skilled in the art can dispose the light source 200 for detection at other positions according to actual needs, including but not limited to being disposed on the first light-shielding structure 300 or the movable arm 112.

[0125] As Figure 1 shown, in order to image-record and / or analyze the morphology of the sample to be detected, especially the morphology in the state held by the holding surface 110, the device of the present utility model may preferably be provided with a photographing device 900. The photographing device 900 may include but not be limited to cameras, video cameras, and other simple optical image sensing elements, etc. Similarly, as Figure 1 shown, the photographing device 900 can be disposed on the above-mentioned mating structure 310 and configured to photograph the sample. However, the installation position of the photographing device 900 is not limited thereto, but can also be located at other positions where the morphology of the sample in the aforementioned enclosed internal space can be photographed, including but not limited to other positions within the enclosed internal space and external positions outside the enclosed internal space but capable of photographing the corresponding sites.

[0126] Continue to refer toFigure 1 , in a preferred embodiment of the device according to the present utility model, in order to improve the illumination brightness in the aforementioned enclosed internal space, the device of the present utility model may further include a supplementary light source 400 for illuminating the aforementioned enclosed internal space in the closed position of the device. The illumination here should be understood as being brighter relative to the case without the supplementary light source 400. The supplementary light source 400 may be, for example, a lighting appliance such as an incandescent lamp, a flash lamp, or an LED light source, or may also include various other devices capable of enhancing the ambient brightness. The supplementary light source 400 may preferably be arranged as shown in Figure 1 on the aforementioned mating structure 310. Specifically, in the preferred embodiment shown in Figure 1 , there may be only one supplementary light source 400 arranged on one side of the aforementioned photographic device 900 and circumferentially spaced apart from the sample and the photographic device 900 in a substantially horizontal plane. However, those skilled in the art can understand that, on the one hand, corresponding supplementary light sources 400 circumferentially spaced apart from the sample and the photographic device 900 horizontally may be arranged on both the left and right sides of the aforementioned photographic device 900. On the other hand, one or more supplementary light sources 400 may also be arranged at different horizontal levels inside the aforementioned enclosed internal space and different from the photographic device 900, and the one or more supplementary light sources 400 do not necessarily need to be circumferentially spaced apart from the photographic device 900 horizontally.

[0127] In addition, in order to obtain a better shooting effect of the sample morphology through the photographic device 900, the present utility model further provides a preferred arrangement scheme for the supplementary light source 400 and the photographic device 900 in the preferred embodiment of Figure 1 .

[0128] Figure 3 shows from a top-down perspective the relative positional relationship between the supplementary light source 400, the photographic device 900, and the sample (sample holding surface 110) in the preferred embodiment of Figure 1 . It should be noted that although both the supplementary light source 400 and the photographic device 900 are preferably arranged on the mating structure 310 in Figure 1 , the mating structure 310 and other peripheral structures are omitted in Figure 3 for clear illustration, and only the relative positional relationship among the supplementary light source 400, the photographic device 900, and the sample is shown.

[0129] As shown in Figure 3 , the photographic device 900 shoots towards the sample along the shooting direction, and the supplementary light source 400 performs supplementary lighting towards the sample along the supplementary lighting direction. The shooting direction and the supplementary lighting direction form a supplementary lighting angle with each other, that is, the photographic device 900 and the supplementary light source 400 are circumferentially spaced apart by a supplementary lighting angle around the sample. Generally speaking, the aforementioned shooting direction can be understood as the connection line between the lens center of the photographic device 900 and the sample center on the horizontal plane (corresponding toFigure 3 In the projection direction on the paper surface), the above-mentioned supplementary light direction can be understood as the projection direction on the horizontal plane of the connection line between the light-emitting center of the supplementary light source 400 and the sample center.

[0130] Now, the preferred numerical range of the supplementary light angle will be further elaborated. Considering the lighting effect of the supplementary light source 400, the range of the above-mentioned supplementary light angle can be selected as 35 degrees to 65 degrees. Further, considering the mechanical cooperation between the fitting structure 310 and the U-shaped housing, the range of the above-mentioned supplementary light angle can be selected as 44 degrees to 56 degrees. Most preferably, in order to obtain a better supplementary light effect, the above-mentioned supplementary light angle can be set to 50 degrees.

[0131] The following refers to Figures 4 to 9 to describe the specific structure of the optical signal output part of the preferred embodiment of the device for detecting components and / or contents in a sample according to the present invention.

[0132] First, refer to Figures 4 to 6 , the device of the present invention may further include an output optical fiber 500.

[0133] The output optical fiber 500 may include a receiving end and an output end 510. Among them, the receiving end ( Figure 4 at the left side in the figure) may be in optical communication with one of the two holding surfaces 110 (for example, the lower holding surface) to transmit the light from the sample, such as the fluorescence excited by the detection light source 200, to the output end 510 via the receiving end, and continue to transmit the optical signal downstream of the output end 510 via the output end 510. In some embodiments, the receiving end may directly abut and contact the corresponding holding surface 110. In some alternative embodiments, the receiving end may not be in direct physical contact with the corresponding holding surface 110, but indirectly receive the light from the sample through one or more intermediate optical elements between the receiving end and the corresponding holding surface 110. It should be noted that although two output optical fibers 500 are shown in the preferred embodiment shown in the figure, those skilled in the art can set fewer or more output optical fibers 500 according to actual needs. It should also be noted that although the two output optical fibers 500 shown in the figure are arranged substantially parallel to each other, those skilled in the art can also arrange the corresponding output optical fibers 500 in a non-parallel configuration according to the actual product structure.

[0134] Refer to Figures 4 to 9 , the device of the present invention may further include an output end mounting bracket 520 and a sensing element mounting bracket 610.

[0135] The output end 510 of the above-mentioned output optical fiber 500 may be mounted on the output side surface 523 of the output end mounting bracket 520 (refer to Figure 5 and Figure 7 ). As Figure 5As shown, the output end 510 of the output optical fiber 500 may preferably be flush with the output side surface 523. However, the output end 510 of the output optical fiber 500 may also protrude beyond the output side surface 523.

[0136] The sensing element mounting bracket 610 is configured to mount the optical signal sensing element 600 and includes a receiving side surface 613 disposed facing the output side surface 523 (see Figure 5 and Figure 8 ). The optical signal sensing element 600 is configured to receive the output light output from the output end 510. Generally, the optical signal sensing element 600 may include one or more optical signal receiving elements such as photodiodes, and such optical signal receiving elements may be used for fluorescence detection, for example. In addition, as shown in the drawings, the optical signal sensing element 600 may further include one or more optical fibers for further conducting the output light, for example, to an ultraviolet spectrophotometer. The optical signal sensing element 600 may preferably be mounted in the sensing element mounting bracket 610 through a circuit board 620 fixed thereto, and there is a circuit board gap between the circuit board 620 and the sensing element mounting bracket 610.

[0137] Thus, a propagation path of the optical signal output from the output end 510 is formed between the output end 510 and the optical signal sensing element 600.

[0138] According to the preferred embodiment shown in the figure, the output end mounting bracket 520 and the sensing element mounting bracket 610 can move relative to each other in a sensing element switching direction perpendicular to the optical axis direction of the output light of the output end 510 (i.e., Figure 5 the horizontal direction in Figure 6 the direction perpendicular to the paper surface in

[0139] The relative movement between both the output terminal mounting bracket 520 and the sensing element mounting bracket 610 can be realized, for example, by driving with a motor M. The motor M can include but is not limited to a stepper motor. Preferably, the motor M can control the movement of the output terminal mounting bracket 520 relative to the sensing element mounting bracket 610 by driving a lead screw that cooperates with the output terminal mounting bracket 520. It should be noted that the arrangement position of the motor M and the specific component on which the output rotational movement acts are not limited to the schematic embodiments shown in the figures, but can also be positioned at other positions where relative movement between both the output terminal mounting bracket 520 and the sensing element mounting bracket 610 can be generated and / or drive the rotation of other components other than the lead screw, including but not limited to being located on the other side of the position of the illustrated motor M relative to the output terminal mounting bracket 520, driving the rotation of the crank of a crank-slider mechanism connected to the output terminal mounting bracket 520, etc., which will not be elaborated here.

[0140] An optoelectronic position sensor 524 can be fixedly provided on the output terminal mounting bracket 520.

[0141] The device of the present utility model can further include a second light-blocking structure. This second light-blocking structure acts downstream of the output terminal 510 to reduce the interference of ambient light on the light output by the output terminal 510.

[0142] See Figure 5 and Figure 6 , the second light-blocking structure can include a first part. The first part of this second light-blocking structure can be provided on at least one of the output side surface 523 and the receiving side surface 613, and preferably is provided on both the output side surface 523 and the receiving side surface 613. The shape of the first part is configured such that it can reduce the light introduced between the output side surface 523 and the receiving side surface 613 onto the output light between the output terminal 510 and the optical signal sensing element 600.

[0143] More specifically, the first part of the second light-blocking structure can include a first light-blocking portion on the output side surface 523 of the output terminal mounting bracket 520 and a second light-blocking portion on the receiving side surface 613 of the sensing element mounting bracket 610. The first light-blocking portion and the second light-blocking portion are staggered with each other in the optical axis direction of the output light and the first light-blocking portion and the second light-blocking portion are spaced apart from each other in the sensing element switching direction.

[0144] Referring to the accompanying drawings ( Figure 5 , Figure 7 and Figure 8) In a preferred embodiment, the first light-shielding portion may include bumps 521 protruding toward the sensing element mounting bracket 610 at both ends of the output side surface 523 in the sensing element switching direction, and the second light-shielding portion may include a groove 611 on the receiving side surface 613, and the bumps 521 are received in the groove 611. The groove 611 and the bumps 521 may be respectively disposed on the output end mounting bracket 520 and the sensing element mounting bracket 610 in an interchangeable manner. It should be noted that the specific shapes and dimensions of the bumps 521 and the groove 611 shown in the figure are only illustrative, and those skilled in the art can also set other shapes of bumps 521 and grooves 611 according to actual needs, as long as they can satisfy the relative movement between the output end mounting bracket 520 and the sensing element mounting bracket 610.

[0145] Referring to the accompanying drawings ( Figure 6 、 Figure 7 and Figure 8 ) In a preferred embodiment, the first light-shielding portion may additionally or alternatively include a guide rail 522 extending along the sensing element switching direction, and the second light-shielding portion may additionally or alternatively include a guiding portion 612 that is shape-matched with the guide rail 522 to allow the guiding portion 612 to move along the guide rail 522. The guide rail 522 and the guiding portion 612 may be respectively disposed on the output end mounting bracket 520 and the sensing element mounting bracket 610 in an interchangeable manner. Similarly, it should be noted that the specific shapes and dimensions of the guide rail 522 and the guiding portion 612 shown in the figure are only illustrative, and those skilled in the art can also set other shapes of the guide rail 522 and the guiding portion 612 according to actual needs, as long as they can satisfy the relative movement between the output end mounting bracket 520 and the sensing element mounting bracket 610.

[0146] The second light-shielding structure may further include a second part. The second part may include a light-shielding material member 700 with pores disposed in the circuit board gap surrounding the optical signal sensing element 600. Such a light-shielding material member 700 with pores may include EMI foam. It should be noted that although the light-shielding material member 700 shown in Figure 9 is a substantially square ring, those skilled in the art can set the light-shielding material member 700 into various other shapes, such as circular, oval, or ovoid rings, according to actual needs.

[0147] The second light-shielding structure may further include a third part. The third part includes a light-shielding cover member 800, and the light-shielding cover member 800 is located on the side of the circuit board 620 facing away from the output optical fiber 500 and can at least partially block the ambient light from this side. Preferably, the light-shielding cover member may include or be made of metal, for example.

[0148] The preferred embodiments of the present utility model have been described in detail above. However, it should be understood that if necessary, aspects of the embodiments can be modified to incorporate aspects, features, and concepts of various patents, applications, and publications to provide additional embodiments.

[0149] In view of the foregoing detailed description, these and other variations can be made to the embodiments described herein. Generally speaking, in the claims, the terms used should not be construed as limited to the specific embodiments disclosed in the specification and claims, but should be understood to include all possible embodiments together with the full scope of equivalents to which the claims are entitled.

Claims

1. A device for detecting components and / or contents in a sample, It is characterized in that include: A sample holding portion (100), the sample holding portion (100) comprising two holding surfaces (110), so that the sample to be tested can be restricted by surface tension and held between the two holding surfaces (110) opposite to each other; A detection light source (200) that emits detection light so that the sample can be excited to emit fluorescence, and at least a portion of the fluorescence can be received at one of the holding surfaces (110); A first light shielding structure (300) at least partially surrounds the sample to be detected to reduce the impact on the detection.

2. The device according to claim 1, It is characterized in that The first light blocking structure (300) is fixedly arranged relative to one of the two holding surfaces (110).

3. The device according to claim 2, It is characterized in that The device comprises a base (111) and a movable arm (112), wherein the two holding surfaces (110) are respectively fixed on the base (111) and the movable arm (112). Wherein, the first light blocking structure (300) is fixedly arranged relative to the movable arm (112), And wherein, the movable arm (112) can move relative to the base (111) so that the device can switch between an open position and a closed position, in which the two holding surfaces (110) are opposite to each other so as to hold the sample by surface tension, and the first light-blocking structure (300) can reduce the influence on detection in the closed position, and in the open position, the first light-blocking structure (300) moves to a position farther away from the base (111) relative to the closed position.

4. The device according to claim 3, It is characterized in that The first light blocking structure (300) comprises a U-shaped cover shell in the circumferential direction. The device also includes a matching structure (310), which faces the U-shaped opening of the cover and is at least partially arranged around the sample to form an enclosed internal space in cooperation with the cover.

5. The device according to claim 4, It is characterized in that The device also includes: A fill light source (400), the fill light source (400) being arranged on the matching structure (310) and configured to illuminate the enclosed internal space in the closed position.

6. The device according to claim 5, It is characterized in that The device also includes: a photographing device (900), the photographing device (900) being configured to photograph the sample, the photographing device (900) being disposed on the matching structure (310), in, The camera device (900) and the supplementary light source (400) are arranged to be spaced apart by a supplementary light angle (α) in a circumferential direction around the sample.

7. The device according to claim 6, It is characterized in that The fill light angle (α) is 35 degrees to 65 degrees.

8. The device according to claim 7, It is characterized in that The fill light angle (α) is 44 degrees to 56 degrees.

9. The device according to claim 8, It is characterized in that The fill light angle (α) is 50 degrees.

10. The device according to claim 1, It is characterized in that include: an output optical fiber (500), the output optical fiber (500) comprising a receiving end and an output end (510), the receiving end being optically connected to one of the two holding surfaces to transmit light from the sample to the output end (510) via the receiving end; an output end mounting frame (520), wherein the output end (510) of the output optical fiber (500) is mounted on an output side surface (523) of the output end mounting frame (520); and a sensing element mounting frame (610), the sensing element mounting frame (610) being configured to mount an optical signal sensing element (600) and comprising a receiving side surface (613) arranged facing the output side surface (523), the optical signal sensing element (600) being configured to receive output light outputted by the output end (510), Wherein, the device further comprises: A second light-blocking structure, the second light-blocking structure includes a first part, the first part is arranged on at least one of the output side surface (523) and the receiving side surface (613), and the shape of the first part is configured to reduce external light introduced between the output side surface (523) and the receiving side surface (613) to the output light between the output end (510) and the optical signal sensing element (600).

11. The device according to claim 10, It is characterized in that The output end mounting frame (520) and the sensing element mounting frame (610) are capable of relative movement relative to each other in a sensing element switching direction perpendicular to the optical axis direction of the output light of the output end (510), and the first part of the second light blocking structure includes a first light blocking portion on the output side surface (523) of the output end mounting frame (520) and a second light blocking portion on the receiving side surface (613) of the sensing element mounting frame (610), the first light blocking portion and the second light blocking portion are staggered with each other in the optical axis direction of the output light and the first light blocking portion and the second light blocking portion are spaced apart from each other in the sensing element switching direction.

12. The device according to claim 11, It is characterized in that The first light shielding portion comprises protrusions (521) on the output side surface (523) at both ends in the switching direction of the sensing element and protruding toward the sensing element mounting frame (610), and the second light shielding portion comprises a groove (611) on the receiving side surface (613), and the protrusion (521) is accommodated in the groove (611). and / or, The first light shielding portion includes a guide rail (522) extending along the switching direction of the sensing element, and the second light shielding portion includes a guide portion (612) that matches the guide rail (522) in shape to allow the guide portion (612) to move along the guide rail (522).

13. The device according to claim 10, It is characterized in that The optical signal sensing element (600) is installed in the sensing element mounting frame (610) via a circuit board (620) fixed thereto, and a circuit board gap exists between the circuit board (620) and the sensing element mounting frame (610). The second light-blocking structure comprises a second part, and the second part comprises a light-blocking material piece (700) containing pores and arranged in a gap of the circuit board surrounding the optical signal sensing element (600).

14. The device according to claim 10, It is characterized in that The optical signal sensing element (600) is mounted in the sensing element mounting frame (610) via a circuit board (620) fixed thereto, and the second light shielding structure includes a third part, and the third part includes a light shielding cover (800), and the light shielding cover (800) is located on a side of the circuit board (620) facing away from the output optical fiber (500) and can at least partially shield ambient light from this side.

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