Detector adaptive to lung cancer early screening technology

Abstract

The utility model discloses a detector adapted to a lung cancer early screening technology, which belongs to the technical field of medical detection instruments and comprises a detector body, a spectrophotometer is mounted above a reaction tank arranged in the detector body, and a signal output end of the spectrophotometer is electrically connected with a signal input end of a controller arranged in the detector body. The positive and negative states of a sample are judged according to color signals in the reaction tank collected by the color sensor, the protein concentration of the sample is judged according to a light absorption value detected by the spectrophotometer, and the positive and negative results and the protein concentration of the sample are displayed through the display, so that the detection of the sample is realized; the method has the advantages of accurate detection, high throughput and low consumption.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical detection instruments, and particularly relates to a detector adapted to the early screening technology of lung cancer. Background Technique

[0002] Lung cancer is a malignant tumor originating from the bronchial mucosa or glands of the lungs. It is one of the malignant tumors with the fastest growth rate of incidence and mortality and the greatest threat to the health and life of the population. At the current medical level, the cure rate of advanced lung cancer is relatively low. The earlier lung cancer is detected, the higher the cure rate. According to the CSCO Lung Cancer Diagnosis and Treatment Guidelines, the main methods for diagnosing lung cancer mainly include: blood markers, ultrasound, and pathological biopsy, etc. These methods all have disadvantages such as low sensitivity, invasiveness, long time consumption, and high detection costs to varying degrees.

[0003] In the prior art, a Chinese patent with the publication number of CN 220709039 U discloses an EVs automatic detector for early screening of lung cancer, which can judge the positive and negative of a sample by the color of the sample to achieve the detection of the sample. However, it cannot detect the protein concentration of the sample.

[0004] Therefore, it is necessary to propose a detector adapted to the early screening technology of lung cancer to solve the above problems. Content of the Utility Model

[0005] In view of this, the purpose of the utility model is to provide a detector adapted to the early screening technology of lung cancer, which is used to solve the problem that the protein concentration of a sample cannot be detected in the prior art.

[0006] To achieve the above purpose, the utility model provides the following technical solutions:

[0007] The utility model provides a detector adapted to the early screening technology of lung cancer, including a detector body. Above the reaction pool arranged inside the detector body, a spectrophotometer is installed. The signal output end of the spectrophotometer is electrically connected to the signal input end of a controller arranged inside the detector body.

[0008] Further, the spectrophotometer is installed between the reaction pool and the color sensor.

[0009] Further, the detector body includes sample pools, and the number of sample pools is 24. Each sample pool is connected to the reaction pool through two microfluidic communication tubes, and one-way valves are arranged inside the microfluidic communication tubes.

[0010] Further, the detector body includes a housing. The reaction pool, the spectrophotometer, the color sensor, the reagent pool, and the sample pools are all installed inside the housing, and a cover body is rotatably installed on the housing.

[0011] Further, a first support frame for supporting a color sensor and a second support frame for supporting a spectrophotometer are installed inside the housing.

[0012] Further, two sets of scissor-type telescopic frames are installed inside the housing, and the first support frame and the second support frame are installed between the two sets of scissor-type telescopic frames. Extending or shortening the scissor-type telescopic frames can synchronously raise or lower the first support frame and the second support frame.

[0013] Further, a strip-shaped sliding hole is provided at the bottom side of the housing, a slider is slidably installed in the strip-shaped sliding hole, one end of the slider extends out of the bottom side of the housing, the first end of the bottom side of the scissor-type telescopic frame is fixedly connected to the bottom wall of the housing, and the second end of the bottom side of the scissor-type telescopic frame is fixedly connected to the slider. Sliding the slider can extend or shorten the scissor-type telescopic frame.

[0014] Further, a connecting rod is fixedly connected between the two sliders extending out of the bottom side of the housing.

[0015] Further, two limiting holes with the same size are provided at the bottom side of the housing, and a plug rod that can cooperate with the limiting holes is elastically connected to the connecting rod.

[0016] The beneficial effects of the present utility model are as follows:

[0017] The color sensor of the present utility model judges the positive and negative of the sample based on the color signal in the reaction pool collected, and then judges the protein concentration of the sample based on the absorbance value detected by the spectrophotometer. The positive and negative results and the protein concentration of the sample are displayed through a display to realize the detection of the sample, which has the advantages of accurate detection, high throughput and low consumption.

[0018] Other advantages, objectives and features of the present utility model will be described in the subsequent description, and to a certain extent, they are obvious to those skilled in the art, or those skilled in the art can be taught from the practice of the present utility model. The objectives and other advantages of the present utility model can be realized and obtained through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to make the objectives, technical solutions and beneficial effects of the present utility model clearer, the following drawings are provided for the present utility model for illustration:

[0020] Figure 1 It is a schematic structural diagram of the detector body according to an embodiment of the present utility model;

[0021] Figure 2 It is a control principle block diagram of the detector body according to an embodiment of the present utility model;

[0022] Figure 3The control principle block diagram of the detector body in the embodiment of the present utility model when a liquid level sensor is provided;

[0023] Figure 4 The installation schematic diagram of the color sensor and the spectrophotometer in the embodiment of the present utility model;

[0024] Figure 5 The schematic diagram of the bottom structure of the housing in the embodiment of the present utility model;

[0025] Figure 6 In the embodiment of the present utility model Figure 5 The enlarged view of the partial A in

[0026] The reference signs in the drawings are as follows: detector body 1, housing 101, cover body 102, strip-shaped sliding hole 103, limiting hole 104, reaction cell 2, spectrophotometer 3, color sensor 4, reagent cell 5, sample cell 6, first support frame 7, second support frame 8, scissor-type telescopic frame 9, slider 10, connecting rod 11, inserting rod 12, spring 13. Detailed implementation manners

[0027] As Figures 1-6 shown, the present utility model provides a detector adapted to the early screening technology of lung cancer, including: a detector body 1. The detector body 1 is an EVs automatic detector for early screening of lung cancer disclosed in a Chinese patent with the publication number of CN 220709039 U, and its specific structure will not be described in detail here. The improvement of this solution is that a spectrophotometer 3 is installed above the reaction cell 2 of the detector body 1, and the signal output end of the spectrophotometer 3 is connected to the signal input end of a controller provided inside the detector body 1.

[0028] In this solution, the detector body 1 detects the liquid in the reaction cell through the color sensor 4 and the spectrophotometer 3. Among them, the color sensor 4 detects the liquid in the reaction cell 2, collects the corresponding color signal and feeds it to the controller. The controller judges the nature of the current test sample according to the color signal, and the nature includes positive and negative. The positive and negative results are displayed on the display; the spectrophotometer judges the nature of the current test sample according to the color signal, and the nature includes the protein concentration signal, and the protein concentration result is displayed on the display; among them, the negative / positive signal and the protein concentration signal generated by the control system are displayed on the display screen of the detector by connecting to the display screen. Words or symbols can be used to represent the positive and negative results and the protein concentration results. Such a design can convert the color change of the mixed solution in the reaction cell 2 into a negative / positive signal and a protein concentration signal on the display screen through optical detection technology, realizing fast and accurate display of test results. When the mixed solution in the reaction cell turns blue, a positive signal will be displayed on the display screen and the protein concentration will be detected; when the mixed solution does not change color, a negative signal will be displayed on the display screen.

[0029] In an embodiment of the present utility model, four reagent pools are provided in the detector body 1, and each reagent pool 5 is connected to a pump valve assembly through a communicating pipe. The pump valve assembly includes a multi-channel steering valve and a micropump. Twenty-four sample pools 6 are provided in the detector body 1, and each sample pool 6 is connected to the reaction cell 2 through two microfluidic communicating pipes. A one-way valve is provided in the microfluidic communicating pipe to prevent the liquid in the sample pool 6 from flowing back into the reaction cell 2. By providing 24 sample pools 6, the richness of sample collection is ensured, and the accuracy of detection is ensured.

[0030] In an embodiment of the present utility model, the detector body 1 includes a housing 101. The reaction cell 2, the spectrophotometer 3, the color sensor 4, the reagent pool 5, and the sample pool 6 are all installed in the housing 101. Among them, a cover body 102 is rotatably installed on the housing 101. Rotating the cover body 102 can supplement samples and related test reagents to the sample pool 6 and the reagent pool 5 provided inside the outer shell 1; a first support frame 7 for supporting the color sensor 4 and a second support frame 8 for supporting the spectrophotometer 3 are installed inside the housing 101. To provide support for the color sensor 4 and the spectrophotometer 3 and ensure the stability of their installation.

[0031] In an embodiment of the present utility model, two sets of scissor-type telescopic frames 9 are installed inside the housing 1. The first support frame 7 and the second support frame 8 are installed between the two sets of scissor-type telescopic frames 9. Extending or shortening the scissor-type telescopic frames 9 can make the first support frame 7 and the second support frame 8 rise or fall synchronously.

[0032] In this solution, after opening the cover 102, the first support frame 7 and the second support frame 8 can be lifted and moved out of the shell 1 by sliding the scissor-type telescopic frame 9, so as to facilitate the replacement of the color sensor 4 and the spectrophotometer 3 and the cleaning of the reaction pool 2.

[0033] In one embodiment of the utility model, a strip sliding hole 103 is provided on the bottom side of the shell 1, and a slider 10 is slidably installed in the strip sliding hole 103, one end of the slider 10 extends out of the bottom side of the shell 1, the first end of the bottom side of the scissors-type telescopic frame 9 is fixedly connected to the bottom wall of the shell 1, and the second end of the bottom side of the scissors-type telescopic frame 9 is fixedly connected to the slider 10, and sliding the slider 10 can extend or shorten the scissors-type telescopic frame 9.

[0034] In this solution, after opening the cover 102, the slider 10 is slid to extend the scissor-type telescopic frame 9 to facilitate replacement of the color sensor 4 and the spectrophotometer 3, or cleaning of the reaction pool 2; the slider 10 is slid to shorten the scissor-type telescopic frame 9 to return the color sensor 4 and the spectrophotometer 3 to the inside of the housing 1.

[0035] In one embodiment of the present invention, a connecting rod 11 is fixedly connected between two sliding blocks 10 extending out of the bottom side of the housing 1 .

[0036] In this solution, the sliding connecting rod 11 can make the two sliding blocks 10 slide synchronously, so that the two groups of scissor-type telescopic frames 9 can be extended or shortened synchronously.

[0037] In one embodiment of the utility model, two limiting holes 104 of the same size are provided on the bottom side of the shell 1, and the connecting rod 11 is elastically connected to an insertion rod 12 that can cooperate with the limiting hole 104, wherein a mounting groove is provided in the connecting rod 11, and the insertion rod 12 is slidably installed in the mounting groove, and a spring 13 is provided between the insertion rod 12 and the inner wall of the mounting groove, and one end of the insertion rod 12 can extend into the limiting hole 104.

[0038] In the present solution, when the detector body 1 is in normal use, the insertion rod 12 is inserted into one of the two limiting holes 104. At this time, the connecting rod 11 cannot be slid, thereby ensuring the stability of the scissors-type telescopic frame 9 in the shortened state; when the scissors-type telescopic frame 9 needs to be extended, the insertion rod 12 is pulled to disengage the insertion rod 12 from the limiting hole 104, and then the connecting rod 11 is slid to extend the scissors-type telescopic frame 9 until the insertion rod 12 is inserted into the other limiting hole 104 of the two limiting holes 104. At this time, the stability of the scissors-type telescopic frame 9 in the extended state is ensured.

[0039] Finally, it should be noted that the above preferred embodiments are only used to illustrate the technical solutions of the present invention rather than to limit them. Although the present invention has been described in detail through the above preferred embodiments, those skilled in the art should understand that various changes can be made in form and details without departing from the scope defined by the claims of the present invention.

Claims

1. A detector adapted for early screening of lung cancer, comprising a detector body, characterized in that: A spectrophotometer is installed above the reaction pool in the detector body, and a signal output end of the spectrophotometer is electrically connected to a signal input end of a controller in the detector body.

2. The detector adapted for early screening of lung cancer according to claim 1, characterized in that: The spectrophotometer is installed between the reaction cell and the color sensor.

3. The detector adapted for early screening of lung cancer according to claim 2, characterized in that: The detector body includes sample pools, the number of which is 24. Each sample pool is connected to a reaction pool via two microfluidic connecting tubes, and a one-way valve is provided in the microfluidic connecting tube.

4. The detector adapted for early screening of lung cancer according to claim 3, characterized in that: The detector body comprises a shell, and the reaction pool, the spectrophotometer, the color sensor, the reagent pool, and the sample pool are all installed in the shell, and a cover body is rotatably installed on the shell.

5. The detector adapted for early screening of lung cancer according to claim 4, characterized in that: A first support frame for supporting the color sensor and a second support frame for supporting the spectrophotometer are installed in the housing.

6. The detector adapted for early screening of lung cancer according to claim 5, characterized in that: Two groups of scissor-type telescopic frames are installed in the shell, and the first support frame and the second support frame are installed between the two groups of scissor-type telescopic frames. Extending or shortening the scissor-type telescopic frames can make the first support frame and the second support frame rise or fall synchronously.

7. The detector adapted for early screening of lung cancer according to claim 6, characterized in that: A strip sliding hole is provided on the bottom side of the shell, a slider is slidably installed in the strip sliding hole, one end of the slider extends out of the bottom side of the shell, a first end of the bottom side of the scissors-type telescopic frame is fixedly connected to the bottom wall of the shell, and a second end of the bottom side of the scissors-type telescopic frame is fixedly connected to the slider, and sliding the slider can extend or shorten the scissors-type telescopic frame.

8. The detector adapted for early screening of lung cancer according to claim 7, characterized in that: A connecting rod is fixedly connected between two sliding blocks extending out of the bottom side of the shell.

9. The detector adapted for early screening of lung cancer according to claim 8, characterized in that: The bottom side of the shell is provided with two limiting holes of the same size, and the connecting rod is elastically connected to an insert rod capable of cooperating with the limiting holes.

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