Mouse sampling metabolism cage

By designing a separator and a convenient sampling mechanism in the mouse sampling metabolic cage, the problems of sample contamination and cumbersome sampling are solved, and the effect of high accuracy and convenient sampling is achieved.

CN223008141UActive Publication Date: 2025-06-24蒋瀚霆
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Patent Information

Application Number
CN202422749924.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-12
Publication Date
2025-06-24
Estimated Expiration
2034-11-12

AI Technical Summary

Technical Problem

Existing mouse sampling metabolic cages are prone to sample contamination and cumbersome sampling problems during use, which affects the accuracy of the analysis and may have an impact on the health of the mice.

Method used

A mouse sampling metabolic cage was designed, using a separator and a sampling mechanism to separate the feeding area and the metabolic area to prevent contamination, and to achieve convenient sampling and replacement of samples through a rotating sampling assembly.

Benefits of technology

It effectively prevents contamination between the feeding area and the metabolic area, simplifies the sampling process, facilitates regular sampling, improves the accuracy of sample analysis and reduces the risk of mouse health.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a mouse sampling metabolism cage which comprises a cage body, a cage cover is arranged at the top of the cage body, a partition plate is arranged in the middle of the cage body, a partition mechanism is arranged on the top face of the partition plate, a feeding mechanism is arranged at one end of the partition mechanism, a dirt discharging mechanism is arranged at the other end of the partition mechanism, and a sampling mechanism for collecting excrement is arranged at the bottom of the dirt discharging mechanism. The separating mechanism comprises a flat plate, an inclined plate and a concave plate. The flat plate is arranged in the middle of the top face of the separating plate. Through the feeding area and the metabolism area formed by the inclined plate and the concave plate in the separation mechanism, mutual pollution between the feeding area and the metabolism area can be prevented, meanwhile, a rotating turntable in the sampling mechanism can rotate the sampling assembly to the outside of the cage body after the sampling assembly contains mouse metabolite, and therefore the mouse metabolite can be conveniently taken out of the cage body. The empty sampling assembly is arranged below the dirt discharging mechanism, so that sampling personnel can conveniently take out the sampling assembly filled with the mouse metabolite and replace the sampling assembly with a new sampling assembly, and the sampling personnel can conveniently sample the metabolite which is regularly and regularly taken for multiple times.
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Description

Technical Field

[0001] The utility model relates to the technical field of mouse sampling and metabolism equipment, in particular to a mouse sampling and metabolism cage. Background Art

[0002] A mouse sampling and metabolism cage is an experimental device specifically used for studying the metabolism of mice. It can collect various excreta (such as urine, feces) and other samples of mice in a relatively independent environment, and study various physiological processes of mice such as energy metabolism and substance metabolism (such as protein, sugar, and fat metabolism) through the analysis of these samples;

[0003] Currently, the following risks may exist during the use of the existing mouse sampling and metabolism cage:

[0004] 1. There will be areas for collecting mouse urine and feces and a feeding trough for placing mouse food inside. Due to the small space inside the sampling and metabolism cage, when mice excrete or eat, it is easy to bring feces and urine into the feeding trough area, or bring food into the excretion area. In this way, sample contamination will occur, affecting the accuracy of later analysis, and at the same time, it may contaminate the mouse food and affect the health of the mice;

[0005] 2. The area for collecting feces and urine samples inside the sampling and metabolism cage is inside the cage, and the area for collecting feces and urine samples is fixed. Conducting multiple samplings is relatively cumbersome and is not conducive to sampling personnel to take samples regularly.

[0006] In summary, there is a need for a mouse sampling and metabolism cage that is not easily contaminated with samples and is convenient for sampling. Content of the Utility Model

[0007] Aiming at the deficiencies of the prior art, the utility model provides a mouse sampling and metabolism cage, which solves the problems mentioned in the background art.

[0008] To achieve the above objectives, the utility model is realized through the following technical solutions:

[0009] A mouse sampling and metabolism cage includes a cage body. A cage cover is provided at the top of the cage body. A partition is provided in the middle of the cage body. A separation mechanism is provided on the top surface of the partition. One end of the separation mechanism is provided with a feeding mechanism, the other end of the separation mechanism is provided with a sewage discharge mechanism, and a sampling mechanism for collecting feces is provided at the bottom of the sewage discharge mechanism;

[0010] The separation mechanism includes a flat plate, an inclined plate, and a concave plate. The flat plate is provided in the middle of the top surface of the partition. One end of the flat plate is provided with an inclined plate, and the other end of the flat plate is provided with a concave plate. The flat plate is inclined. A collection groove is formed in the middle of the concave plate. The collection groove has an inverted conical structure. A collection port is opened at the bottom of the collection groove, and the collection port is correspondingly arranged with the sewage discharge mechanism and the sampling mechanism;

[0011] The top surface of the cage body is provided with a cage cover, the end of the cage body is provided with a baffle, the end of the baffle is provided with a mounting opening, and the mounting opening is arranged corresponding to the dirt discharge mechanism.

[0012] Furthermore, the top surface of the flat plate is provided with convex strips 1, which are distributed in an array, and the top surface of the concave plate is provided with a plurality of convex strips 2.

[0013] Furthermore, the feeding mechanism is engaged and slidably engaged with the cage body, and the feeding mechanism is mirrored at the end of the inclined plate. The feeding mechanism includes a connecting plate, a feeding box and a handle. The feeding box is provided on one side of the connecting plate, and a handle is provided on the side of the connecting plate away from the feeding box.

[0014] Furthermore, the dirt discharge mechanism comprises a mounting plate, a dirt discharge net and two handles. The dirt discharge net is provided at the end of the mounting plate, and the two handles are provided on the top surface of the mounting plate. The dirt discharge net engages and slides with the mounting opening.

[0015] Furthermore, the sampling mechanism includes a mounting seat, a motor, a turntable and an anti-slip annular sheet. The mounting seat is arranged inside the cage body, a motor is arranged in the middle of the mounting seat, a turntable is arranged at the output end of the motor, an anti-slip annular sheet is arranged on the top surface of the turntable, a sampling component is arranged on the top surface of the anti-slip annular sheet, and the sampling components are distributed in a circle on the top surface of the turntable.

[0016] Furthermore, the sampling assembly includes a sampling box, a spacer and a sampling net. The spacer is provided in the middle of the inner side of the sampling box, and the sampling net is provided on the top surface of the spacer. The sampling net is snap-connected with the sampling box.

[0017] The utility model provides a mouse sampling metabolic cage. Compared with the prior art, it has the following beneficial effects:

[0018] The feeding area and the metabolic area formed by the inclined plate and the concave plate in the separation mechanism can prevent mutual contamination between the feeding area and the metabolic area. At the same time, the rotating turntable in the sampling mechanism can rotate the sampling component to the outside of the cage after the sampling component receives the mouse metabolites, and place the empty sampling component under the decontamination mechanism, thereby making it convenient for the sampling personnel to take out the sampling component containing the mouse metabolites and replace it with a new sampling component, and making it convenient for the sampling personnel to conduct multiple regular and periodic metabolite sampling. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 A schematic diagram of the structure of a mouse sampling metabolic cage of the utility model is shown;

[0021] Figure 2 Shows a schematic internal structure diagram of the cage body of the present utility model;

[0022] Figure 3 Shows a schematic structural diagram of the partitioning mechanism of the present utility model;

[0023] Figure 4 Shows a schematic structural diagram of the dirt discharging mechanism of the present utility model;

[0024] Figure 5 Shows a schematic structural diagram of the sampling mechanism of the present utility model;

[0025] Figure 6 Shows a schematic distribution diagram of the sampling components of the present utility model;

[0026] Figure 7 Shows a schematic structural diagram of the sampling components of the present utility model;

[0027] Figure 8 Shows a schematic structural diagram of the partitioning plug board of the present utility model;

[0028] As shown in the figure: 1. Cage body; 11. Cage cover; 12. Partition board; 13. Baffle; 14. Installation opening; 2. Feeding mechanism; 21. Connecting plate; 22. Feeding box; 23. Pull handle one; 3. Sampling mechanism; 31. Mounting seat; 32. Motor; 33. Turntable; 34. Anti-slip annular piece; 35. Sampling box; 36. Partition block; 37. Sampling net; 4. Partitioning mechanism; 41. Flat plate; 42. Inclined plate; 43. Concave plate; 44. First convex strip; 45. Second convex strip; 5. Dirt discharging mechanism; 51. Mounting plate; 52. Dirt discharging net; 53. Pull handle two; 6. Partitioning plug board. Detailed implementation manners

[0029] To make the objectives, technical solutions and advantages of the embodiments of the present utility model clearer, the technical solutions in the embodiments of the present utility model are described clearly and completely. Apparently, the described embodiments are some, but not all, of the embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0030] Embodiment 1

[0031] To solve the technical problems in the background art, the following mouse sampling and metabolism cage is provided:

[0032] Combined with Figures 1 - 8As shown, the utility model provides a mouse sampling metabolism cage, including a cage body 1, a cage cover 11 is provided on the top of the cage body 1, a partition 12 is provided in the middle of the cage body 1, a metabolic zone and a feeding zone are formed at both ends of the partition 12, a partition mechanism 4 is provided on the top surface of the partition 12, and the partition mechanism 4 can prevent mutual contamination between the feeding zone and the metabolic zone, a feeding mechanism 2 for feeding mice is provided at one end of the partition mechanism 4, a sewage discharge mechanism 5 is provided at the other end of the partition mechanism 4, and a sampling mechanism 3 for collecting feces is provided at the bottom of the sewage discharge mechanism 5, and the partition mechanism 4 includes a flat plate 41, an inclined plate 42 and a concave plate 43, the flat plate 41 is provided in the middle of the top surface of the partition 12, and the flat plate 41 is provided in the middle of the top surface of the partition 12. An inclined plate 42 is provided at one end, and a concave plate 43 is provided at the other end of the flat plate 41. The flat plate 41 is inclined, and a collecting groove is formed in the middle of the concave plate 43. The collecting groove is an inverted cone structure. The inverted cone collecting groove located in the metabolic zone can prevent mice from bringing metabolites that may adhere to the sewage discharge mechanism 5 to the flat plate 41 or the feeding zone. A collecting port is provided at the bottom of the collecting tank, and the collecting port is correspondingly arranged with the sewage discharge mechanism 5 and the sampling mechanism 3. The inclined plate 42 can prevent mice from bringing food in the feeding zone into the metabolic zone. A partition plug 6 is provided in the middle of the cage cover 11, and the partition plug 6 is engaged with the cage cover 11, so as to isolate mice in the feeding zone or the metabolic zone.

[0033] A cage cover 11 is provided on the top surface of the cage body 1, and a baffle 13 is provided at the end of the cage body 1. The baffle can cover the opening of the sampling mechanism 3, and an installation opening 14 is provided at the end of the baffle 13. The installation opening 14 is arranged corresponding to the sewage discharge mechanism 5, and the installation opening 14 is used to install and replace the sewage discharge mechanism 5;

[0034] In this embodiment, the top surface of the flat plate 41 is provided with a convex strip 44, which is distributed in an array, and the top surface of the concave plate 43 is provided with a plurality of convex strips 45, which can assist the mouse in walking and prevent the mouse from slipping;

[0035] In this embodiment, the feeding mechanism 2 is engaged and slid with the cage body 1, and the feeding mechanism 2 can be drawn out of the cage body 1 for cleaning or replacement of food and water. The feeding mechanism 2 is mirrored at the end of the inclined plate 42, and the feeding mechanism 2 includes a connecting plate 21, a feeding box 22 and a handle 23. The feeding box 22 is provided on one side of the connecting plate 21, and the handle 23 is provided on the side of the connecting plate 21 away from the feeding box 22. The feeding box 22 is used to hold food for mice;

[0036] As an improvement of the above-mentioned scheme, the sewage discharge mechanism 5 includes a mounting plate 51, a sewage discharge net 52 and a handle 53. The sewage discharge net 52 is provided at the end of the mounting plate 51, and the handle 53 is provided on the top surface of the mounting plate 51. The sewage discharge net 52 engages and slides with the mounting port 14. The sewage discharge net 52 can ensure that the excrement of mice can fall into the sampling mechanism 3. Under the engagement and sliding action of the sewage discharge net 52 and the mounting port 14, it is convenient for the sampling personnel to replace the new sewage discharge mechanism 5.

[0037] Embodiment 2

[0038] As Figures 2 - 7 shown, on the basis of the above embodiments, the following content is further given in this embodiment:

[0039] For the convenience of the sampling personnel to sample the metabolites of the mice, the following design is given in this embodiment:

[0040] The sampling mechanism 3 includes a mounting base 31, a motor 32, a turntable 33 and an anti-slip annular piece 34. The mounting base 31 is arranged inside the cage body 1. A motor 32 is arranged in the middle of the mounting base 31. The output end of the motor 32 is provided with the turntable 33. The motor 32 can provide power for the rotation of the turntable 33. The top surface of the turntable 33 is provided with the anti-slip annular piece 34. The anti-slip annular piece 34 can ensure that the sampling assembly is stably placed above the turntable 33. The top surface of the anti-slip annular piece 34 is provided with the sampling assembly. The sampling assemblies are distributed in a ring on the top surface of the turntable 33. The sampling assemblies distributed in a ring can sequentially rotate to receive the metabolites of the mice;

[0041] As an improvement of the above solution, the sampling assembly includes a sampling box 35, a partition block 36 and a sampling net 37. A partition block 36 is arranged in the middle of the inner side of the sampling box 35. The top surface of the partition block 36 is provided with the sampling net 37. The sampling net 37 is snap-connected to the sampling box 35. The sampling net 37 can collect the feces of the mice and at the same time ensure that the urine of the mice can pass through normally and flow into the bottom of the sampling box 35. After the mice excrete, the metabolites will fall into the sampling box 35 in the sampling assembly. The sampling net 37 separates the urine and feces. At this time, the motor 32 drives the turntable 33 to rotate, so that the sampling assembly rotates to the outside of the cage body 1, and the empty sampling assembly is placed under the sewage discharging mechanism 5. In this way, it is convenient for the sampling personnel to replace the new sampling assembly and perform multiple timed and regular metabolite samplings.

[0042] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover a non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the phrase "including a..." does not exclude the existence of additional identical elements in the process, method, article or device including the element.

[0043] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A mouse sampling metabolic cage, characterized in that: It comprises a cage body (1), wherein a cage cover (11) is provided on the top of the cage body (1), a partition plate (12) is provided in the middle of the cage body (1), a partition mechanism (4) is provided on the top surface of the partition plate (12), a feeding mechanism (2) is provided at one end of the partition mechanism (4), a sewage discharge mechanism (5) is provided at the other end of the partition mechanism (4), and a sampling mechanism (3) for collecting feces is provided at the bottom of the sewage discharge mechanism (5); The partition mechanism (4) comprises a flat plate (41), an inclined plate (42) and a concave plate (43); the flat plate (41) is arranged in the middle of the top surface of the partition plate (12); one end of the flat plate (41) is provided with the inclined plate (42); the other end of the flat plate (41) is provided with the concave plate (43); the flat plate (41) is arranged in an inclined manner; a collecting groove is formed in the middle of the concave plate (43); the collecting groove is in an inverted cone structure; a collecting port is provided at the bottom of the collecting groove; the collecting port is arranged corresponding to the dirt discharge mechanism (5) and the sampling mechanism (3); The top surface of the cage body (1) is provided with a cage cover (11), the end of the cage body (1) is provided with a baffle (13), the end of the baffle (13) is provided with a mounting opening (14), and the mounting opening (14) is arranged corresponding to the dirt discharge mechanism (5).

2. A mouse sampling metabolic cage according to claim 1, characterized in that: The top surface of the flat plate (41) is provided with a convex strip one (44), the convex strips one (44) are distributed in an array, and the top surface of the concave plate (43) is provided with a plurality of convex strips two (45).

3. A mouse sampling metabolic cage according to claim 2, characterized in that: The feeding mechanism (2) is engaged and slidably engaged with the cage body (1), and the feeding mechanism (2) is mirror-imaged at the end of the inclined plate (42). The feeding mechanism (2) comprises a connecting plate (21), a feeding box (22) and a handle (23). The feeding box (22) is provided on one side of the connecting plate (21), and the handle (23) is provided on the side of the connecting plate (21) facing away from the feeding box (22).

4. A mouse sampling metabolic cage according to claim 1, characterized in that: The dirt removal mechanism (5) comprises a mounting plate (51), a dirt removal net (52) and two handles (53); the dirt removal net (52) is provided at the end of the mounting plate (51); the two handles (53) are provided on the top surface of the mounting plate (51); and the dirt removal net (52) is slidably engaged with the mounting opening (14).

5. A mouse sampling metabolic cage according to claim 1, characterized in that: The sampling mechanism (3) comprises a mounting seat (31), a motor (32), a rotating disk (33) and an anti-skid annular sheet (34); the mounting seat (31) is arranged inside the cage body (1); a motor (32) is arranged in the middle of the mounting seat (31); a rotating disk (33) is arranged at the output end of the motor (32); an anti-skid annular sheet (34) is arranged on the top surface of the rotating disk (33); a sampling assembly is arranged on the top surface of the anti-skid annular sheet (34); and the sampling assembly is distributed in a ring on the top surface of the rotating disk (33).

6. A mouse sampling metabolic cage according to claim 5, characterized in that: The sampling assembly comprises a sampling box (35), a spacer (36) and a sampling net (37); the spacer (36) is provided at the middle of the inner side of the sampling box (35); the sampling net (37) is provided on the top surface of the spacer (36); and the sampling net (37) is snap-fitted and connected to the sampling box (35).