Antigen dilution assisting and temporary storage device
By engraving the dilution volume value and dilution concentration value on the placement plate of the antigen dilution auxiliary and temporary storage device, and using the cooling components to maintain the sample temperature stability, the problem of low detection titer caused by operating errors and temperature changes during sample dilution is solved, and more accurate and reliable detection results are achieved.
Patent Information
- Application Number
- CN202422045681.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-22
- Publication Date
- 2025-06-24
- Estimated Expiration
- 2034-08-22
AI Technical Summary
During the dilution of the sample of the carbohydrate antigen C199, operational errors are prone to occur when the sample is large, and the temperature changes in the sample affect the activity, resulting in low detection titer.
An antigen dilution assistance and temporary storage device is designed, including a support member and a placing plate provided on the inner wall of the box. The placing plate is engraved with dilution volume value and dilution concentration value. The placing liquid is filled with coolant and a cooling component is installed to maintain the sample temperature stability.
The risk of operating errors is reduced by scale marking, and the cooling components maintain consistent sample temperature to ensure the perfection of the test results.
Smart Images

Figure CN223015387U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to an antigen dilution assisting and temporary storage device, belonging to the technical field of antigen diluent temporary storage. Background Art
[0002] During the research and development of carbohydrate antigen C199, sample dilution is required. When there is a large amount of samples, operation errors such as taking the wrong sample or misdiluting are likely to occur, affecting the later detection results; moreover, after the samples are taken out of the refrigerator, the temperature difference between the ambient temperature and the sample storage temperature is relatively large, affecting the activity of the samples and resulting in problems such as low detection titer. Content of the Utility Model
[0003] The purpose of the utility model is to provide an antigen dilution assisting and temporary storage device, which can reduce the risk of operation errors during the dilution process of carbohydrate antigen C199 samples, and at the same time can ensure the activity of the samples during the experiment to obtain relatively perfect detection results.
[0004] In order to achieve the above purpose, the technical solution adopted by the utility model is as follows:
[0005] An antigen dilution assisting and temporary storage device includes a box body. A plurality of supporting members are correspondingly arranged on the inner wall of the box body. A placement plate is installed on the plurality of supporting members, and a plurality of groups of through holes for inserting antigen test tubes are provided on the placement plate; the dilution volume values corresponding to each horizontal row of through holes are engraved on the top surface of the placement plate, and the dilution concentration values corresponding to each vertical row of through holes are engraved on the top surface of the placement plate; a cooling liquid is filled in the box body below the placement plate, and cooling components for cooling the cooling liquid are installed on both sides of the box body.
[0006] Preferably, the cooling component includes a semiconductor refrigeration sheet. A cold guide plate is arranged at the cold end of the semiconductor refrigeration sheet, and a heat conduction plate is arranged at the hot end; an installation plate is arranged outside the heat conduction plate, and a fan for dissipating heat from the heat conduction plate is installed on the installation plate; a notch for the cold guide plate to be embedded and contact with the cooling liquid is provided on the box body, and the installation plate is fixed outside the box body.
[0007] Preferably, an opening corresponding to the heat conduction plate is provided on the installation plate.
[0008] Preferably, the semiconductor refrigeration sheet is connected to the cold guide plate and the heat conduction plate, and the heat conduction plate is connected to the installation plate through silicone.
[0009] Preferably, a sealing member is further arranged between the cold guide plate and the notch.
[0010] Preferably, a controller is arranged on the front end face of the box body, and a sensor for detecting the temperature of the cooling liquid is installed in the box body. The sensor, the semiconductor refrigeration sheet and the fan are all electrically connected to the controller.
[0011] Preferably, a storage box is provided on the rear end face of the box body, and a storage battery is provided in the storage box. The storage battery is used to supply power to the sensor, the semiconductor refrigeration sheet, the fan and the controller.
[0012] Preferably, a pipe for introducing or discharging the coolant is provided on the box body, and a valve is further provided on the pipe; and an observation window for observing the coolant level in the box body is further provided on the front end face of the box body.
[0013] Preferably, a cover body is further covered on the box body.
[0014] Preferably, an isolation sleeve for supporting the sample test tube is provided in each through hole.
[0015] The beneficial effects of the utility model are as follows:
[0016] 1. By engraving the dilution volume value and the dilution concentration value on the placement plate, the situation of operation errors easily caused by excessive samples can be reduced.
[0017] 2. The cooling component cools the coolant and acts on the sample in the test tube, so that its temperature is as close as possible to the storage environment, avoiding the problem of low detection titer caused by the change of sample activity due to temperature difference.
[0018] 3. By providing an isolation sleeve at the through hole, it can prevent cold air from entering above the isolation plate to cause water vapor condensation, and prevent the condensed water from dripping into the test tube when the test tube cap is opened. Description of the Drawings
[0019] Figure 1 It is the front view of the antigen dilution auxiliary and temporary storage device;
[0020] Figure 2 It is the rear view of the antigen dilution auxiliary and temporary storage device;
[0021] Figure 3 It is the front view of the placement plate;
[0022] Figure 4 It is the top view of the placement plate;
[0023] Figure 5 It is the structural schematic diagram of the cooling component.
[0024] The meanings of the main reference numerals in the drawings are as follows:
[0025] 1. Box body, 2. Cover body, 3. Support member, 4. Placing plate, 5. Through hole, 6. Isolation sleeve, 7. Dilution volume value, 8. Dilution concentration value, 9. Pipeline, 10. Valve, 11. Observation window, 12. Cooling assembly, 13. Thermoelectric cooler, 14. Heat conduction plate, 15. Heat conducting plate, 16. Mounting plate, 17. Fan, 18. Controller, 19. Sensor, 20. Accommodating box, 21. Storage battery. Specific implementation manner
[0026] The following specifically introduces the present utility model in conjunction with the accompanying drawings and embodiments.
[0027] This embodiment is an antigen dilution assistance and temporary storage device. As shown in Figures 1-4 , it includes a box body 1 and a cover body 2 covering the top of the box body 1. A plurality of support members 3 are correspondingly arranged on the inner wall of the box body 1. A placing plate 4 is installed on the plurality of support members 3. The outer extension of the placing plate 4 is in close contact with the inner wall of the box body 1. An effective seal can also be ensured by setting a sealing member between the placing plate 4 and the box body 1. The placing plate 4 is provided with a plurality of groups of through holes 5 for inserting antigen test tubes. An isolation sleeve 6 (with heat conduction ability) for supporting the sample test tube is arranged in each through hole 5. The dilution volume value 7 corresponding to each horizontal row of through holes 5 and the dilution concentration value 8 corresponding to each vertical row of through holes 5 are engraved on the top surface of the placing plate 4. The setting of the dilution volume value 7 and the dilution concentration value 8 on the placing plate 4 can facilitate the operator to take and place the test tubes, and reduce the occurrence of operation errors easily caused by too many samples.
[0028] As shown in Figure 1 , 3 , 5, in order to avoid the problem of low detection titer caused by the change of sample activity due to temperature difference, the box body 1 below the placing plate 4 is filled with coolant, and a pipeline 9 for introducing or discharging the coolant is arranged on the box body 1. At the same time, a valve 10 is arranged on the pipeline 9, and an observation window 11 for observing the liquid level of the coolant in the box body 1 is arranged on the front end face of the box body 1.
[0029] In order to cool down the coolant to ensure that the temperature of the antigen sample before and after dilution in the test tube is maintained within a certain range, cooling components 12 are installed on both sides of the box body 1. The cooling component 12 includes a thermoelectric cooler 13. The cold end of the thermoelectric cooler 13 is provided with a cold conduction plate 14, and the hot end is provided with a heat conduction plate 15. Both the cold conduction plate 14 and the heat conduction plate 15 are metal plates with heat conduction ability; an installation plate 16 is arranged on the outer side of the heat conduction plate 15, and a fan 17 for dissipating heat from the heat conduction plate 15 is installed on the installation plate 16; a notch for the cold conduction plate 14 to be embedded and contact with the coolant is formed on the box body 1, and the installation plate 16 is fixed on the outer side of the box body 1. The thermoelectric cooler 13 is connected to the cold conduction plate 14 and the heat conduction plate 15, and the heat conduction plate 15 is connected to the installation plate 16 through silicone. Moreover, a seal is arranged between the cold conduction plate 14 and the notch to prevent the coolant from seeping into the thermoelectric cooler 13; further, an opening corresponding to the heat conduction plate 15 is formed on the installation plate 16 to improve the heat dissipation effect of the hot end of the thermoelectric cooler 13.
[0030] In order to facilitate the control of the temperature of the coolant, a controller 18 is arranged on the front end face of the box body 1, and a sensor 19 for detecting the temperature of the coolant is installed inside the box body 1. The sensor 19, the thermoelectric cooler 13, and the fan 17 are all electrically connected to the controller 18. At the same time, a storage box 20 is arranged on the rear end face of the box body 1, and a storage battery 21 is arranged inside the storage box 20. The storage battery 21 is used to supply power to the sensor 19, the thermoelectric cooler 13, the fan 17, and the controller 18. Among them, the specific circuit connection relationship and control relationship are all prior art and will not be elaborated here.
[0031] During actual operation, the storage battery 21 supplies power to the thermoelectric cooler 13, and the same temperature as the original storage temperature is set through the controller 18. The cold end of the thermoelectric cooler 13 cools down and acts on the coolant through the cold conduction plate 14 to lower its temperature. When the fan 17 rotates, it can dissipate the heat conducted to the heat conduction plate 15 at the hot end of the thermoelectric cooler 13, so as to improve the refrigeration efficiency of the cold end of the thermoelectric cooler 13. After the temperature reaches the set temperature, the operator removes the cover body 2, then takes out the test tube containing the antigen sample from the refrigerator, inserts it into the isolation sleeve 6 of the through hole 5, covers the cover body 2, and transfers it to the antigen dilution place for dilution treatment. When diluting the antigen sample, the diluted sample test tube can be inserted into the isolation sleeve 6 again according to the dilution volume value 7 and the dilution concentration value 8 on the placement plate 4.
[0032] The above is only the preferred embodiment of the utility model patent. It should be noted that for those of ordinary skill in the art, without departing from the principle of the utility model patent, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the utility model patent.
Claims
1. An antigen dilution auxiliary and temporary storage device, characterized in that: The invention comprises a box body, on the inner wall of which a plurality of supporting members are correspondingly arranged, a placing plate is installed on the plurality of supporting members, and a plurality of through holes for inserting antigen test tubes are provided on the placing plate; a dilution volume value corresponding to each horizontal row of through holes is engraved on the top surface of the placing plate, and a dilution concentration value corresponding to each vertical row of through holes is engraved on the top surface of the placing plate; a cooling liquid is filled in the box body located below the placing plate, and cooling components for cooling the cooling liquid are installed on both sides of the box body.
2. The antigen dilution auxiliary and temporary storage device according to claim 1, characterized in that: The cooling assembly includes a semiconductor refrigeration plate, a cold end of the semiconductor refrigeration plate is provided with a cold conduction plate, and a hot end is provided with a heat conduction plate; a mounting plate is provided on the outer side of the heat conduction plate, and a fan for dissipating heat from the heat conduction plate is installed on the mounting plate; a slot is opened on the box body for the cold conduction plate to be embedded and contact with the coolant, and the mounting plate is fixed on the outer side of the box body.
3. The antigen dilution auxiliary and temporary storage device according to claim 2, characterized in that: An opening corresponding to the heat conducting plate is provided on the mounting plate.
4. The antigen dilution auxiliary and temporary storage device according to claim 2, characterized in that: The semiconductor refrigeration sheet and the cold-conducting plate, the heat-conducting plate, and the heat-conducting plate and the mounting plate are all connected via silicone.
5. The antigen dilution auxiliary and temporary storage device according to claim 2, characterized in that: A sealing member is also provided between the cooling plate and the notch.
6. The antigen dilution auxiliary and temporary storage device according to claim 2, characterized in that: A controller is arranged on the front end surface of the box body, and a sensor for detecting the temperature of the coolant is installed in the box body. The sensor, the semiconductor cooling sheet and the fan are all electrically connected to the controller.
7. The antigen dilution auxiliary and temporary storage device according to claim 6, characterized in that: A containing box is arranged on the rear end surface of the box body, and a storage battery is arranged in the containing box. The storage battery is used to supply power to the sensor, the semiconductor cooling sheet, the fan and the controller.
8. The antigen dilution auxiliary and temporary storage device according to claim 1, characterized in that: A pipeline for introducing or discharging the coolant is arranged on the box body, and a valve is also arranged on the pipeline; and an observation window for observing the coolant level in the box body is also arranged on the front end surface of the box body.
9. The antigen dilution auxiliary and temporary storage device according to claim 1, characterized in that: The box body is also covered with a cover body.
10. The antigen dilution auxiliary and temporary storage device according to claim 1, characterized in that: An insulating sleeve for supporting the sample test tube is arranged in each through hole.