Phototoxicity exposure rat fixer

Abstract

The utility model relates to a phototoxicity exposure rat fixer, which comprises a body fixing area and a head fixing area, the body fixing area comprises a bottom plate arranged at the bottom, side plates are fixedly mounted on the left side and the right side of the bottom plate, a partition plate is fixedly mounted between the tops of the opposite sides of the two side plates, and a fixing plate is fixedly mounted on the head fixing area. A first light shield and a second light shield are movably installed between the tops of the two side plates, the head fixing area comprises a pressing plate movably installed between the front sides of the two side plates, a fixing plate is fixedly installed between the rear sides of the two side plates, and a cover plate is hinged to the top of the fixing plate. According to the phototoxicity exposure rat fixer, the photophobic design is adopted, a safe and comfortable environment is provided for a rat by utilizing the physiological characteristic that the rat likes a dark environment, only the skin of an area needing to be experimented is exposed, and due to the design, not only is the rat prevented from being excessively stimulated, but also the risk that experimenters are bitten is reduced; meanwhile, the experiment is more convenient and safer.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental animal fixation, in particular to a light toxicity exposure rat fixator. Background Technique

[0002] Laboratory rats rank second only to mice in biomedical research. Due to their advantages such as moderate body size, fast reproduction, easy feeding and management, and convenient drug administration, they have become important experimental animals in biomedical research. Rats not only have many similarities with humans in terms of physiology and anatomy, but also have characteristics suitable for various experimental operations, thus playing an important role in multiple research fields.

[0003] In animal experiments, fixing rats is to ensure the smooth progress of the experiment and the safety of experimental personnel and animals. Correctly fixing rats is crucial for obtaining accurate scientific data and also helps to reduce the stress and pain of animals.

[0004] Traditional rat fixators mostly adopt rigid structures to restrict the activities of animals to achieve the purpose of fixation. Moreover, due to the physiological characteristic of rats being photophobic, if the whole body is exposed, this will inevitably bring various stimulations to rats, making them often in a state of stress or irritation. Rats in this state may not only harm experimental personnel but also affect the accuracy of psychological and behavioral observations. Therefore, a light toxicity exposure rat fixator is proposed to solve the above problems. Content of the Utility Model

[0005] (1) Technical Problems to be Solved

[0006] Aiming at the deficiencies of the prior art, the utility model provides a light toxicity exposure rat fixator, which has the advantages of avoiding light stimulation, only exposing the skin of the area that needs to be experimented, and separating the head and the body into two cavities. It solves the problems that traditional rat fixators mostly adopt rigid structures to restrict the activities of animals to achieve the purpose of fixation, and due to the physiological characteristic of rats being photophobic, if the whole body is exposed, this will inevitably bring various stimulations to rats, making them often in a state of stress or irritation. Rats in this state may not only harm experimental personnel but also affect the accuracy of psychological and behavioral observations.

[0007] (2) Technical Solutions

[0008] To achieve the above object, the present utility model provides the following technical solutions: A phototoxic exposure rat fixator, comprising a body fixation area and a head fixation area. The body fixation area includes a bottom plate disposed at the bottom. On both left and right sides of the bottom plate, side plates are fixedly installed. Between the tops of the two opposite side plates, a partition plate is fixedly installed. Between the tops of the two side plates, a light-shielding cover one and a light-shielding cover two are movably installed. The head fixation area includes a pressing plate movably installed between the front sides of the two side plates. Between the rear sides of the two side plates, a fixing plate is fixedly installed. At the top of the fixing plate, a cover plate is hinged.

[0009] Preferably: A connecting plate connecting between the front sides of the two side plates is fixedly installed at the top of the bottom plate. An excretion hole is opened inside the partition plate.

[0010] Preferably: On both left and right sides of the light-shielding cover one and the light-shielding cover two, two slot holes one are opened. The light-shielding cover one and the light-shielding cover two are connected between the left and right sides of the two side plates through four handle screws one passing through the slot holes one.

[0011] Preferably: Four leakage holes and a triangular mark are opened at the top of the light-shielding cover one.

[0012] Preferably: Two slot holes two are opened inside the pressing plate. The pressing plate is connected between the front sides of the two side plates through two handle screws two passing through the slot holes two.

[0013] Preferably: A semi-circular hole is opened at the bottom of the pressing plate.

[0014] (III) Beneficial effects

[0015] Compared with the prior art, the technical solution of the present application has the following beneficial effects:

[0016] 1. For this phototoxic exposure rat fixator, by setting the body fixation area and the head fixation area, the body and head of the rat can be respectively fixed inside the body fixation area and the head fixation area, and the fixation range can be flexibly adjusted according to the different sizes of the rat's volume.

[0017] 2. This phototoxic exposure rat fixator adopts a light-shielding design. Utilizing the physiological characteristic that rats like dark environments, it provides a safe and comfortable environment for them, only exposing the skin of the area that needs to be experimented. This design not only avoids excessive stimulation to the rats, but also reduces the risk of being bitten by the rats for the experimenters, and at the same time makes the experiment more convenient and safe. Description of the drawings

[0018] Figure 1 It is a three-dimensional structural schematic diagram of the present utility model;

[0019] Figure 2Schematic diagram of the three-dimensional structure of another form of the present utility model;

[0020] Figure 3 Front view structure schematic diagram of the present utility model;

[0021] Figure 4 Top view structure schematic diagram of the present utility model.

[0022] In the figure: 1. Body fixing area; 101. Bottom plate; 102. Side plate; 103. Partition board; 104. Light-shielding cover one; 105. Light-shielding cover two; 2. Head fixing area; 201. Pressing plate; 202. Fixing plate; 203. Cover plate; 301. Connecting plate; 3. Slot one; 4. Handle screw one; 5. Slot two; 6. Handle screw two; 7. Semi-circular hole. Specific implementation mode

[0023] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0024] Please refer to Figures 1-4 , the photo-toxic exposure rat fixator in this embodiment includes a body fixing area 1 and a head fixing area 2. The body fixing area 1 includes a bottom plate 101 arranged at the bottom. Side plates 102 are fixedly installed on both the left and right sides of the bottom plate 101. A partition board 103 is fixedly installed between the tops of the two opposite side plates 102. A light-shielding cover one 104 and a light-shielding cover two 105 are movably installed between the tops of the two side plates 102. The head fixing area 2 includes a pressing plate 201 movably installed between the front sides of the two side plates 102. A fixing plate 202 is fixedly installed between the rear sides of the two side plates 102. A cover plate 203 is hinged to the top of the fixing plate 202.

[0025] Example 1: The fixator consists of a body fixation area 1 and a head fixation area 2. The body fixation area 1 includes a bottom plate 101, with a side plate 102 installed on each side. A partition plate 103 is installed between the tops of these two side plates 102, forming a support platform. In addition, a light-shielding cover 104 and a light-shielding cover 105 are movably installed between the two side plates 102. The light-shielding cover 104 and the light-shielding cover 105 are used for selection according to experimental requirements to cover and fix the body part of the rat. The head fixation area 2 is composed of a pressing plate 201 movably installed between the front sides of the two side plates 102, a fixing plate 202 fixedly installed between the rear sides of the two side plates 102, and a cover plate 203 hinged to the top of the fixing plate 202. The head fixation area 2 is used to fix the head of the rat, and the fixed body part of rats with different sizes can be adjusted and fixed by changing the height of the light-shielding cover 104 and the light-shielding cover 105, while the fixation of different head sizes can be adjusted and fixed by changing the height of the pressing plate 201.

[0026] The functions of the light-shielding cover 104 and the light-shielding cover 105 are to meet different lighting experiments. One is to illuminate the skin of the neck part, and the other is to illuminate the skin of the back.

[0027] Specifically, the body of the rat can be placed on the top of the partition plate 103, and according to the experimental project, the light-shielding cover 104 or the light-shielding cover 105 is selected to cover the body of the rat. By pressing down from top to bottom, according to the different sizes of the rats, the slot holes 3 on both sides of the light-shielding cover 104 or the light-shielding cover 105 are pressed down to a fixed space suitable for the size of the rat. After that, the threaded parts of the four handle screws 1 are inserted into the appropriate positions in the corresponding slot holes 3. On the other side, the fixing parts, that is, the nuts, on the four handle screws 1 are tightened on the handle screws 1 to lock the positions of the light-shielding cover 104 and the light-shielding cover 105, completing the fixation of the body part of the rat.

[0028] When fixing the head of the rat, one hand inserts the head of the rat into the semi-circular hole 7, and at the same time, the other hand promptly presses the pressing plate 201. The two hands cooperate to clamp the neck of the rat, and the handle screw 2 6 is promptly tightened. That is, according to the thickness of the neck of the rat, the pressing plate 201 is pressed down. The pressing plate 201 drives the slot hole 2 5 to move down to a suitable size space for neck fixation. After the threaded parts of the two handle screws 2 6 are inserted into the corresponding slot holes 2 5, the position of the pressing plate 201 is fixed by tightening the nut on the handle screw 2 6 on the other side of the pressing plate 201, completing the fixation of the head of the rat.

[0029] Such a design enables the fixator to adapt to rats of different sizes, ensuring the stability and safety of animals during the experiment, and also providing convenient operability for experimenters.

[0030] Embodiment 2: A cover plate 203 is hinged to the top of the fixing plate 202. The cover plate 203 is fixed to the top of the fixing plate 202 by a hinge and can be freely flipped.

[0031] Specifically, the head of the rat is fixed in the head fixing area 2. When the cover plate 203 is closed, a cave imitating weak light is formed inside the head fixing area 2. The head of the rat is in the light-shielded area, and the body is in the light-shielding cover 104 or the light-shielding cover 105. The neck of the rat is restricted by the pressing plate 201 in terms of the forward and backward movement range. The whole body of the rat is in a cave imitating weak light, and only the local skin that needs to be experimented is exposed.

[0032] Such a design enables the fixator to provide a more comfortable environment for fixing the rat, making the rat more stable during the whole experiment process, reducing the stress generated, and facilitating the experiment.

[0033] Embodiment 3: A connecting plate 301 connected between the front sides of the two side plates 102 is fixedly installed on the top of the bottom plate 101. A discharge hole is opened inside the partition plate 103.

[0034] Specifically, a liquid collecting tank is formed between the bottom plate 101 and the connecting plate 301. The partition plate 103 is the main body for supporting the rat. The discharge holes opened on its surface are used to discharge the excreta of the rat. Under the action of gravity, the excreta are timely led into the liquid collecting tank formed by the bottom plate 101 and the connecting plate 301, preventing the excreta from polluting the rat body fixing area 1 and the experimental chamber.

[0035] Four leakage holes and a triangular mark are opened on the top of the light-shielding cover 104. The light-shielding cover 104 can meet the light exposure experiment on the back skin of the rat. The light-shielding cover 105 can meet the light exposure experiment on the neck skin of the rat. In addition to being used for phototoxic exposure experiments, this fixator can also be widely applied to other experimental scenarios that require fixing rats, such as drug screening, acute toxicity tests, etc. Its design is also applicable to mice, further expanding the scope of use.

[0036] All the parts involved above are made of black light-shielding acrylic.

[0037] In summary, for this phototoxic exposure rat fixator, by setting the body fixing area 1 and the head fixing area 2, the body and head of the rat can be respectively fixed inside the body fixing area 1 and the head fixing area 2, and the fixing range can be flexibly adjusted according to the different sizes of the rat volume.

[0038] Moreover, with a light-shielding design, taking advantage of the physiological characteristic that rats like dark environments, a safe and comfortable environment is provided for them, and only the area skin that needs to be experimented is exposed. This design not only avoids excessive stimulation to the rats, but also reduces the risk of being bitten by the experimental personnel, and at the same time makes the experiment more convenient and safe.

[0039] It should be noted that, in this document, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, such that a process, method, article or device comprising a series of elements not only includes those elements but also includes other elements not expressly listed, or elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "comprising an..." does not exclude the presence of additional identical elements in the process, method, article or device comprising the said element.

[0040] Although embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A rat fixator for phototoxic exposure, comprising a body fixation area (1) and a head fixation area (2), characterized in that: The body fixing area (1) comprises a bottom plate (101) arranged at the bottom, side plates (102) are fixedly installed on both the left and right sides of the bottom plate (101), a partition plate (103) is fixedly installed between the tops of the two opposite sides of the two side plates (102), a sunshade 1 (104) and a sunshade 2 (105) are movably installed between the tops of the two side plates (102), and the head fixing area (2) comprises a pressure plate (201) movably installed between the front sides of the two side plates (102), a fixing plate (202) is fixedly installed between the rear sides of the two side plates (102), and a cover plate (203) is hinged on the top of the fixing plate (202).

2. The phototoxic exposure rat fixator according to claim 1, characterized in that: A connecting plate (301) connected between the front sides of the two side plates (102) is fixedly mounted on the top of the bottom plate (101), and a drainage hole is provided inside the partition plate (103).

3. The phototoxic exposure rat fixator according to claim 1, characterized in that: Two slot holes (3) are provided on both sides of the left side of the light shield (104) and the light shield (105). The light shield (104) and the light shield (105) are connected between the left and right sides of the two side panels (102) by four handle screws (4) passing through the slot holes (3).

4. The phototoxic exposure rat holder according to claim 1, characterized in that: The top of the light shield (104) is provided with four leak holes and a triangular mark.

5. The phototoxic exposure rat fixator according to claim 1, characterized in that: The pressing plate (201) has two slot holes (5) formed inside, and the pressing plate (201) is connected between the front sides of the two side plates via two handle screws (6) penetrating the slot holes (5).

6. The phototoxic exposure rat fixator according to claim 1, characterized in that: A semicircular hole (7) is provided at the bottom of the pressing plate (201).

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