Stem cell exosome preservation device

Abstract

The utility model relates to the technical field of storage instruments, and provides a stem cell exosome preservation device which comprises a preservation box, a hollow box is fixedly connected to the right surface of the preservation box, a sliding groove is formed in the front side of the right surface of the hollow box, and bottom plates are movably connected to the lower surfaces of the preservation box and the hollow box. Through the arrangement of the preservation box, the first movable box, the second movable box, the toothed plate and the gear, firstly, an operator disassembles clamping teeth and fixing bolts, at the moment, rotation locking of the clamping teeth on the gear is relieved, then the operator rotates the gear, due to the fact that the toothed plate is meshed with the gear, the toothed plate is driven by rotation of the gear, and the gear is prevented from being damaged. The bottom plate, the first movable box, the second movable box and the toothed plate move downwards together, and the overall height of the storage box and the second movable box is changed in the process, so that the sample tanks with different heights can be stored in the overall storage box and the second movable box.

Description

Technical Field

[0001] The utility model relates to the technical field of instrument storage, and specifically, to a preservation device for stem cell exosomes. Background Art

[0002] Exosomes are tiny extracellular vesicles with a diameter of about 30 - 150 nanometers. They are secreted by various cell types and exist in various body fluids. Exosomes play an important role in intercellular communication and can carry and transmit various biomolecules such as proteins, lipids, and nucleic acids. Due to their unique biological characteristics and functions, exosomes are considered to have great potential in disease diagnosis, treatment, and regenerative medicine.

[0003] Before operators detect stem cell exosomes, they need to use a preservation device to properly preserve the stem cell exosomes. However, in the actual use of the existing preservation devices, although they have basic preservation functions, the height of the existing preservation devices is generally fixed and cannot be adjusted according to the height of the storage test tubes. Therefore, it needs to be improved. Summary of the Utility Model

[0004] The utility model provides a preservation device for stem cell exosomes, which solves the problem of non - adjustable height in the related art.

[0005] The technical solution of the utility model is as follows: A preservation device for stem cell exosomes includes a preservation box. The right surface of the preservation box is fixedly connected with a hollow box. The front side of the right surface of the hollow box is provided with a sliding groove. The lower surfaces of both the preservation box and the hollow box are movably connected with a bottom plate. The left side of the upper surface of the bottom plate is fixedly connected with a second movable box located inside the preservation box. The outer surface of the second movable box is movably connected with the inner surface of the preservation box. The upper surface of the bottom plate is fixedly connected with a first movable box located inside the hollow box. The outer surface of the first movable box is movably connected with the inner surface of the hollow box. The inner surface of the sliding groove is movably connected with a toothed plate. The left end of the toothed plate is fixedly connected with the right surface of the first movable box. The right surface of the hollow box is fixedly connected with a fixing ring located behind the toothed plate. The outer surface of the fixing ring is movably installed with a gear. The outer surface of the gear is meshed with the outer surface of the toothed plate.

[0006] As a preferred technical solution of the utility model, the right side of the outer surface of the gear is meshed with a locking tooth. The outer surface of the locking tooth is movably connected with a fixing bolt. The other end of the fixing bolt sequentially penetrates through the locking tooth and the hollow box and extends into the interior of the hollow box. The outer surface of the fixing bolt is threadedly sleeved with the inner surface of the hollow box.

[0007] As a preferred technical solution of the present utility model, a cover plate is hinged to the top of the rear surface of the storage box, and a handle is fixedly connected to the upper surface of the cover plate.

[0008] As a preferred technical solution of the present utility model, a fixed clamping plate is fixedly connected to the upper side of the inner surface of the storage box, a movable clamping plate is movably connected to the inner surface of the storage box, a connecting plate is fixedly connected to the lower surface of the movable clamping plate, a connecting rod is fixedly connected to the left surface of the connecting plate, the right end of the connecting rod penetrates through the storage box and extends into the interior of the hollow box, and the outer surface of the connecting rod is movably sleeved with the inner surface of the storage box.

[0009] As a preferred technical solution of the present utility model, the number of the connecting rods is two, and the right ends of the two connecting rods are both fixedly connected with driving blocks located inside the hollow box.

[0010] As a preferred technical solution of the present utility model, springs are movably sleeved on the outer surfaces of the two connecting rods, the right ends of the springs are fixedly connected to the right side of the inner surface of the storage box, and the left ends of the springs are fixedly connected to the right surface of the connecting plate.

[0011] As a preferred technical solution of the present utility model, a rotating shaft is movably connected to the middle of the upper surface of the hollow box, the bottom end of the rotating shaft penetrates through the hollow box and extends into the interior of the hollow box, and a driving rod is fixedly sleeved on the bottom end of the outer surface of the rotating shaft.

[0012] As a preferred technical solution of the present utility model, a cylinder is movably connected to the inner surface of the driving block, the top end of the cylinder penetrates through the driving rod and extends to the upper surface of the driving rod, and the outer surface of the cylinder is fixedly sleeved with the driving rod.

[0013] As a preferred technical solution of the present utility model, limiting rings are fixedly sleeved on the outer surface of the rotating shaft, the number of the limiting rings is two, and the outer surfaces of the two limiting rings are both movably connected with the hollow box.

[0014] As a preferred technical solution of the present utility model, a rotating handle located above the limiting ring is fixedly sleeved on the top end of the outer surface of the rotating shaft, and the outer surface of the rotating handle is smooth.

[0015] The beneficial effects of the present utility model are:

[0016] 1. The utility model is provided with a storage box, a first movable box, a second movable box, a toothed plate and a gear. First, the operator removes the locking tooth and the fixing bolt. At this time, the rotation locking of the locking tooth to the gear is released. Then, the operator rotates the gear. Since the toothed plate and the gear are meshed with each other, the toothed plate will be driven by the rotation of the gear, so that the bottom plate, the first movable box, the second movable box and the toothed plate move downward together. During this process, the overall height of the storage box and the second movable box will change. Thus, the interior of the storage box and the second movable box as a whole can store sample cans of different heights.

[0017] 2. The utility model is provided with a movable clamping plate, a connecting plate, a connecting rod, a driving block and a cylinder. When the operator rotates the rotating handle, the rotating shaft, the driving rod, the cylinder and the limiting ring will all rotate under the drive of the rotating handle. The rotation of the cylinder will drive the driving block, so that the driving block, the connecting rod, the connecting plate and the movable clamping plate start to move rightward under the limitation of the inner surface of the storage box. This makes the distance between the movable clamping plate and the connecting plate gradually increase. Thus, the movable clamping plate and the connecting plate can fix sample cans of different diameters. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The following further describes the present utility model in detail with reference to the drawings and specific embodiments.

[0019] Figure 1 is a schematic structural diagram of the present utility model;

[0020] Figure 2 is a schematic side structural diagram of the present utility model;

[0021] Figure 3 is a schematic sectional structural diagram of the present utility model;

[0022] Figure 4 is a schematic sectional structural diagram of the top of the present utility model;

[0023] Figure 5 is a schematic sectional structural diagram of the fixing ring of the present utility model.

[0024] In the figure: 1, storage box; 2, hollow box; 3, bottom plate; 4, first movable box; 5, second movable box; 6, sliding groove; 7, toothed plate; 8, gear; 9, fixing ring; 10, locking tooth; 11, fixing bolt; 12, cover plate; 13, handle; 14, fixing clamping plate; 15, movable clamping plate; 16, connecting plate; 17, connecting rod; 18, driving block; 19, spring; 20, rotating shaft; 21, driving rod; 22, cylinder; 23, limiting ring; 24, rotating handle. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0025] Next, in combination with the embodiments of the present utility model, the technical solutions in the embodiments of the present utility model will be clearly and completely described. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts fall within the scope of protection of the present utility model.

[0026] As Figures 1 to 5 shown, the present utility model provides a preservation device for stem cell exosomes, including a preservation box 1. A hollow box 2 is fixedly connected to the right surface of the preservation box 1. A sliding groove 6 is formed in the front side of the right surface of the hollow box 2. The lower surfaces of both the preservation box 1 and the hollow box 2 are movably connected to a bottom plate 3. A second movable box 5 located inside the preservation box 1 is fixedly connected to the left side of the upper surface of the bottom plate 3. The outer surface of the second movable box 5 is movably connected to the inner surface of the preservation box 1. A first movable box 4 located inside the hollow box 2 is fixedly connected to the upper surface of the bottom plate 3. The outer surface of the first movable box 4 is movably connected to the inner surface of the hollow box 2. A toothed plate 7 is movably connected to the inner surface of the sliding groove 6. The left end of the toothed plate 7 is fixedly connected to the right surface of the first movable box 4. A fixing ring 9 located behind the toothed plate 7 is fixedly connected to the right surface of the hollow box 2. A gear 8 is movably installed on the outer surface of the fixing ring 9. The outer surface of the gear 8 is meshed with the outer surface of the toothed plate 7.

[0027] When the operator rotates the gear 8, since the toothed plate 7 and the gear 8 are meshed with each other, the toothed plate 7 will be driven by the rotation of the gear 8, causing the bottom plate 3, the first movable box 4, the second movable box 5 and the toothed plate 7 to start moving downward together.

[0028] Among them, a locking tooth 10 is meshed with the right side of the outer surface of the gear 8. The outer surface of the locking tooth 10 is movably connected to a fixing bolt 11. The other end of the fixing bolt 11 sequentially penetrates through the locking tooth 10 and the hollow box 2 and extends into the interior of the hollow box 2. The outer surface of the fixing bolt 11 is threadedly sleeved with the inner surface of the hollow box 2.

[0029] When the locking tooth 10 is in a meshed state with the gear 8, the rotation function of the gear 8 will be locked by the locking tooth 10, and the design of the fixing bolt 11 enables the locking tooth 10 to be disassembled.

[0030] Among them, a cover plate 12 is hinged to the top of the rear surface of the preservation box 1. A handle 13 is fixedly connected to the upper surface of the cover plate 12.

[0031] The outer shape design of the handle 13 facilitates the operator to grasp and pull it.

[0032] Among them, a fixed clamping plate 14 is fixedly connected to the upper side of the inner surface of the storage box 1, a movable clamping plate 15 is movably connected to the inner surface of the storage box 1, a connecting plate 16 is fixedly connected to the lower surface of the movable clamping plate 15, a connecting rod 17 is fixedly connected to the left surface of the connecting plate 16, the right end of the connecting rod 17 penetrates through the storage box 1 and extends into the interior of the hollow box 2, and the outer surface of the connecting rod 17 is movably sleeved with the inner surface of the storage box 1.

[0033] The designs of the movable clamping plate 15 and the connecting plate 16 can clamp and fix the sample cans.

[0034] Among them, the number of the connecting rods 17 is two, and driving blocks 18 located inside the hollow box 2 are fixedly connected to the right ends of the two connecting rods 17.

[0035] The design of the two connecting rods 17 ensures the stability when the movable clamping plate 15 and the connecting plate 16 move.

[0036] Among them, springs 19 are movably sleeved on the outer surfaces of the two connecting rods 17, the right ends of the springs 19 are fixedly connected to the right side of the inner surface of the storage box 1, and the left ends of the springs 19 are fixedly connected to the right surface of the connecting plate 16.

[0037] The design of the springs 19 enables the whole movable clamping plate 15 to automatically move leftward under the elastic force of the springs 19, and finally the sample cans are clamped and fixed between the fixed clamping plate 14 and the movable clamping plate 15.

[0038] Among them, a rotating shaft 20 is movably connected to the middle of the upper surface of the hollow box 2, the bottom end of the rotating shaft 20 penetrates through the hollow box 2 and extends into the interior of the hollow box 2, and a driving rod 21 is fixedly sleeved on the bottom end of the outer surface of the rotating shaft 20.

[0039] The rotating shaft 20 and the driving rod 21 can rotate around the rotating shaft 20 as the axis.

[0040] Among them, a cylinder 22 is movably connected to the inner surface of the driving block 18, the top end of the cylinder 22 penetrates through the driving rod 21 and extends to the upper surface of the driving rod 21, and the outer surface of the cylinder 22 is fixedly sleeved with the driving rod 21.

[0041] The cylinder 22 will rotate together with the driving rod 21, and the rotation of the cylinder 22 will also drive the driving block 18, so that the driving block 18, the connecting rod 17 and the whole movable clamping plate 15 move left and right.

[0042] Among them, a limiting ring 23 is fixedly sleeved on the outer surface of the rotating shaft 20, the number of the limiting rings 23 is two, and the outer surfaces of the two limiting rings 23 are movably connected to the hollow box 2.

[0043] The design of the limiting ring 23 limits the whole rotating shaft 20.

[0044] Wherein, a rotating handle 24 located above the limiting ring 23 is fixedly sleeved on the top end of the outer surface of the rotating shaft 20, and the outer surface of the rotating handle 24 is smooth.

[0045] The design of the rotating handle 24 facilitates the operator to rotate the entire rotating shaft 20.

[0046] The working principle and usage process of the present utility model are as follows:

[0047] When the height of the test tank is greater than the overall height of the storage box 1, the operator first removes the locking teeth 10 and the fixing bolts 11, and then rotates the gear 8. Since the outer surfaces of the toothed plate 7 and the gear 8 are meshed with each other, the rotation of the gear 8 will drive the toothed plate 7, causing the bottom plate 3, the first movable box 4, the second movable box 5 and the toothed plate 7 to move downward along the inner surfaces of the storage box 1 and the sliding groove 6 together. During this process, the distance between the bottom plate 3 and the storage box 1 will gradually increase until the overall internal height of the storage box 1 and the second movable box 5 meets the storage requirement of the test tank.

[0048] Then the operator rotates the rotating handle 24. At this time, the entire rotating shaft 20 and the entire driving rod 21 will start to rotate, and the cylinder 22 will drive the driving block 18 during this process, causing the driving block 18, the connecting rod 17 and the movable clamping plate 15 to move to the right as a whole. This makes the distance between the movable clamping plate 15 and the fixed clamping plate 14 gradually increase. When the distance between the fixed clamping plate 14 and the movable clamping plate 15 meets the storage requirement of the sample tank, the operator places the sample tank between the fixed clamping plate 14 and the movable clamping plate 15 and releases the rotating handle 24. At this time, under the elastic force of the spring 19, the movable clamping plate 15 will start to move to the left as a whole, and finally the movable clamping plate 15 and the fixed clamping plate 14 will clamp the outer surface of the sample tank to realize the fixation of the sample tank.

[0049] The above is only the preferred embodiment of the present utility model, and it is not intended to limit the present utility model. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included in the protection scope of the present utility model.

Claims

1. A stem cell exosome storage device, comprising a storage box (1), characterized in that: The right surface of the storage box (1) is fixedly connected to a hollow box (2), the front side of the right surface of the hollow box (2) is provided with a sliding groove (6), the lower surfaces of the storage box (1) and the hollow box (2) are both movably connected to a bottom plate (3), the left side of the upper surface of the bottom plate (3) is fixedly connected to a second movable box (5) located inside the storage box (1), the outer surface of the second movable box (5) is movably connected to the inner surface of the storage box (1), and the upper surface of the bottom plate (3) is fixedly connected to the second movable box (5) located inside the hollow box (2). A movable box (4) is provided, wherein the outer surface of the movable box (4) is movably connected to the inner surface of the hollow box (2), the inner surface of the sliding groove (6) is movably connected to a toothed plate (7), the left end of the toothed plate (7) is fixedly connected to the right surface of the movable box (4), the right surface of the hollow box (2) is fixedly connected to a fixing ring (9) located at the rear side of the toothed plate (7), the outer surface of the fixing ring (9) is movably mounted with a gear (8), and the outer surface of the gear (8) is meshingly connected to the outer surface of the toothed plate (7).

2. A stem cell exosome storage device according to claim 1, characterized in that: The right side of the outer surface of the gear (8) is meshingly connected with a latch tooth (10), and the outer surface of the latch tooth (10) is movably connected with a fixing bolt (11), and the other end of the fixing bolt (11) passes through the latch tooth (10) and the hollow box (2) in sequence and extends into the interior of the hollow box (2), and the outer surface of the fixing bolt (11) and the inner surface of the hollow box (2) are threadedly sleeved.

3. A stem cell exosome storage device according to claim 1, characterized in that: A cover plate (12) is hingedly connected to the top of the rear surface of the storage box (1), and a handle (13) is fixedly connected to the upper surface of the cover plate (12).

4. A stem cell exosome storage device according to claim 1, characterized in that: A fixed clamp (14) is fixedly connected to the upper side of the inner surface of the storage box (1), a movable clamp (15) is movably connected to the inner surface of the storage box (1), a connecting plate (16) is fixedly connected to the lower surface of the movable clamp (15), a connecting rod (17) is fixedly connected to the left surface of the connecting plate (16), the right end of the connecting rod (17) passes through the storage box (1) and extends to the inside of the hollow box (2), and the outer surface of the connecting rod (17) is movably connected to the inner surface of the storage box (1).

5. A stem cell exosome storage device according to claim 4, characterized in that: There are two connecting rods (17), and the right ends of the two connecting rods (17) are fixedly connected to a driving block (18) located inside the hollow box (2).

6. A stem cell exosome storage device according to claim 4, characterized in that: The outer surfaces of the two connecting rods (17) are movably sleeved with springs (19), the right end of the spring (19) is fixedly connected to the right side of the inner surface of the storage box (1), and the left end of the spring (19) is fixedly connected to the right surface of the connecting plate (16).

7. A stem cell exosome storage device according to claim 1, characterized in that: A rotating shaft (20) is movably connected to the middle of the upper surface of the hollow box (2), the bottom end of the rotating shaft (20) passes through the hollow box (2) and extends into the interior of the hollow box (2), and a driving rod (21) is fixedly sleeved on the bottom end of the outer surface of the rotating shaft (20).

8. A stem cell exosome storage device according to claim 5, characterized in that: The inner surface of the driving block (18) is movably connected to a cylinder (22), the top end of the cylinder (22) penetrates the driving rod (21) and extends to the upper surface of the driving rod (21), and the outer surface of the cylinder (22) is fixedly sleeved with the driving rod (21).

9. A stem cell exosome storage device according to claim 7, characterized in that: A limiting ring (23) is fixedly sleeved on the outer surface of the rotating shaft (20), the limiting rings (23) are two in number, and the outer surfaces of the two limiting rings (23) are both movably connected to the hollow box (2).

10. A stem cell exosome storage device according to claim 7, characterized in that: A rotating handle (24) located above the limiting ring (23) is fixedly sleeved on the top end of the outer surface of the rotating shaft (20), and the outer surface of the rotating handle (24) is smooth.

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