Microimaging and visible component detection device with distance fine adjustment assembly

By using dual imaging modules and distance fine-tuning components in the microscopic imaging device, the problem of inflexible image acquisition in the prior art is solved, efficient and fast image acquisition is achieved, and the timeliness of detection is improved.

CN223051576UActive Publication Date: 2025-07-01SHENZHEN ANLV MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202421897081.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-07
Publication Date
2025-07-01
Estimated Expiration
2034-08-07

AI Technical Summary

Technical Problem

In the prior art, the microscopic image acquisition device is not flexible enough, resulting in low image acquisition efficiency and affecting the timeliness of detection, especially when a large number of images at different positions or different focal surfaces are required.

Method used

A micro-imaging device with distance fine-tuning components was designed, using a dual camera module and distance fine-tuning components, which can flexibly adjust the magnification and distance, and improve image acquisition efficiency.

Benefits of technology

Through the combination of the dual-camera module and the distance fine-tuning component, the microscopic imaging device can quickly and flexibly acquire images of multiple angles and multiple focal lengths, significantly improving image acquisition efficiency and shortening detection time.

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Abstract

The microscopic imaging and visible component detection device with the distance fine adjustment assembly comprises a camera module A, a supporting assembly and the distance fine adjustment assembly A, the supporting assembly is used for mounting and supporting; the distance fine adjustment assembly A comprises a lens cone B, a lens cone A and a directional guide rail, the lens cone B and the lens cone A comprise internal through holes, and an imaging light path can pass through the internal through holes; the camera module A is mechanically connected with the lens cone A; the lens cone A is sleeved on the lens cone B, the lens cone B is in threaded connection with the lens cone A, the directional guide rail is mechanically connected with the lens cone A, and the lens cone A can move in the linear direction under the action of the directional guide rail; in the rotation process of the lens cone B, the lens cone A is driven to move in the linear direction; the lens cone A drives the camera module A to move in the linear direction. According to the microscopic imaging device capable of adjusting the distance, the magnification factor can be adjusted, and meanwhile, the image acquisition efficiency is greatly improved by adopting the form of double camera modules.
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Description

Technical Field

[0001] This application belongs to the field of microscopic imaging image technology, and particularly relates to a microscopic imaging and formed element detection device with a distance fine-tuning component. Background Art

[0002] The pixel points of the image sensor in a digital microscope are fixed. During the microscopic imaging process, the larger the magnification, the smaller the field of view of the digital camera. When using a 40x magnifying glass, the area captured by the digital camera is approximately in the range of 0.2 mm wide and 0.3 mm long. If the height of the accommodation cavity for the detection chip is 0.2 mm, the volume captured in one picture is 0.012 cubic millimeters. In most detection scenarios, there are requirements for the sample volume of the detection object. Therefore, many pictures need to be taken at different positions or different focal planes. Many times, the number of pictures that need to be taken exceeds 1000, which takes a long time and seriously affects the timeliness of detection. Many times, for the target objects in the detection sample, such as cells, bacteria, etc., there are requirements for the detection duration. If it exceeds the set time, the cell membrane may rupture, resulting in incorrect measurement of the sample.

[0003] In the prior art, during the formed element analysis process, most image acquisition is carried out in the form of a single camera module with a fixed magnification. Although the consistency of the acquired images is good, it is not flexible enough and the image acquisition efficiency is not high. Summary of the Invention

[0004] In this application, the problem that the formed element analysis image acquisition device in the prior art is not flexible enough is solved. A microscopic imaging device capable of distance adjustment is designed, which can adjust the magnification and, at the same time, adopts the form of a dual camera module, greatly improving the image acquisition efficiency.

[0005] The technical solution of this application to solve the above technical problems is a microscopic imaging device with a distance fine-tuning component, including camera module A, a support component, and distance fine-tuning component A; the support component is used for installation and support; the distance fine-tuning component A includes lens barrel B, lens barrel A, and a directional guide rail. Lens barrel B and lens barrel A include internal through holes, and the imaging optical path can pass through the above internal through holes; camera module A is mechanically connected to the above lens barrel A; lens barrel A is sleeved on lens barrel B, and lens barrel B and lens barrel A are connected by threads. Under the action of the directional guide rail, lens barrel A can move in a straight line direction; when lens barrel B rotates, it drives lens barrel A to move in a straight line direction; lens barrel A drives camera module A to move in a straight line direction.

[0006] The above microscopic imaging device with a distance fine-tuning component further includes camera module B and beam splitter A; the imaging optical path is split by beam splitter A into two optical paths, and camera module A forms an image on one optical path; camera module B forms an image on the other optical path.

[0007] The above-mentioned microscopic imaging device with a distance fine-tuning component further includes a distance fine-tuning component B; the distance fine-tuning component B includes a lens barrel B, a lens barrel A, and a directional guide rail. The lens barrel B and the lens barrel A include internal through holes, and the imaging optical path can pass through the above internal through holes; the camera module B is mechanically connected to the above lens barrel A; the lens barrel A is sleeved on the lens barrel B, and the lens barrel B and the lens barrel A are connected by threads. Under the action of the directional guide rail, the lens barrel A can move in a straight line direction; during the rotation of the lens barrel B, the lens barrel A is driven to move in a straight line direction; the lens barrel A drives the camera module B to move in a straight line direction.

[0008] The above-mentioned microscopic imaging device with a distance fine-tuning component further includes a beam splitter B and a marking light component; the beam splitter B splits an optical path into a marking optical path, and the marking light component emits marking light, which forms a marking pattern on the detection target through the marking optical path. The marking pattern passes through the imaging optical path and is imaged on the above camera module A and / or camera module B to form a marking image.

[0009] The support component includes a mounting hole for the marking light component, and the marking light component is connected to the above marking optical path through the above mounting hole.

[0010] The above-mentioned microscopic imaging device with a distance fine-tuning component further includes a lens module. The lens module includes a turntable and at least two groups of lenses. The above lenses are mounted on the turntable, and by rotating the turntable, different lenses are switched into the optical path.

[0011] The above-mentioned microscopic imaging device with a distance fine-tuning component further includes a lens module. The lens module is connected in series with the beam splitter A and the camera module A in the vertical direction, and the distance fine-tuning component A is used to drive the camera module A to move in the vertical direction.

[0012] The above-mentioned microscopic imaging device with a distance fine-tuning component further includes a lens module. The lens module is connected in series with the beam splitter A and the camera module B in the vertical direction, and the distance fine-tuning component A is used to drive the camera module A to move in the horizontal direction.

[0013] The above-mentioned lens module includes a motor A and a gear set A. The gear set A is respectively gear-connected to the motor A and the above turntable, and the motor A drives the turntable to rotate through the gear set A.

[0014] The above-mentioned lens module further includes a position sensor, and the above position sensor is used to detect the position of the disk teeth.

[0015] The above-mentioned distance fine-tuning component A or distance fine-tuning component B further includes a gear set B and a motor B; the input end of the gear set B is mechanically connected to the shaft of the motor B; the output end of the gear set B is mechanically connected to the lens barrel B; the rotational output of the motor B passes through the gear set B to drive the lens barrel B to rotate; when the lens barrel B rotates, it drives the lens barrel A to move up and down.

[0016] The distance fine-tuning component A or the distance fine-tuning component B further includes a position sensor, and the position sensor is used to detect the position of the lens barrel A.

[0017] The technical solution for this application to solve the above technical problem can also be a formed component detection device, including a microscopic imaging device with a distance fine-tuning component.

[0018] The above formed component detection device further includes a Z-axis movement component. The Z-axis movement component is fixedly connected to the microscopic imaging device with a distance fine-tuning component and is used to drive the microscopic imaging device with a distance fine-tuning component to move in the Z-axis direction.

[0019] The technical effects of the above technical solution include: The distance fine-tuning component A can adjust the distance. When the types of target analytes are different and the magnification required for imaging needs to be adjusted, it can respond flexibly to obtain clear images.

[0020] The technical effects of the above technical solution include: Through the beam splitter A and the imaging module B, multiple imaging modules are used to obtain images at different distances at the same position, and more abundant image information can be provided at one time.

[0021] The technical effects of the above technical solution include: The distance fine-tuning component B enables the imaging module B to also adjust the distance, further flexible the image acquisition mechanism.

[0022] The technical effects of the above technical solution include: The setting of the beam splitter B and the marker light component enables the imaging to introduce markers, facilitating subsequent positioning and calculation.

[0023] The technical effects of the above technical solution include: The marker light component mounting hole facilitates the access of different marker light components to meet the imaging requirements of different scenarios.

[0024] The technical effects of the above technical solution include: The lens module can switch different lenses into the optical path, meeting more abundant imaging requirements.

[0025] The technical effects of the above technical solution include: The distance fine-tuning component A is used to drive the imaging module A to move in the vertical direction. The distance fine-tuning component A is used to drive the imaging module A to move in the horizontal direction. It can flexibly set the movement in different directions to adapt to different scenarios.

[0026] The technical effects of the above technical solution include: The lens module can also be electrically controlled, which is the basis for realizing the automatic adjustment of the entire imaging process.

[0027] The technical effects of the above technical solution include: The electrical control of the distance fine-tuning component A enables the distance adjustment to achieve automatic adjustment.

[0028] The technical effects of the above technical solution include: the position sensor provides adjusted position information, enabling more accurate control.

[0029] The technical effects of the above technical solution include: the formed element detection device based on the above microscopic imaging device can achieve image acquisition at multiple distances; at the same time, the multi-camera module can achieve simultaneous acquisition of multiple images, greatly improving the image acquisition efficiency, shortening the image acquisition time, and providing richer image information for subsequent image analysis. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figures 1 to 3 is a schematic block diagram of a microscopic imaging device with a distance fine-tuning component Figures 1 to 3 ;

[0031] Figures 4 to 6 is a partial schematic of a microscopic imaging device with a distance fine-tuning component Figures 1 to 3 ;

[0032] Figure 7 is a schematic diagram of a local part in a microscopic imaging device with a distance fine-tuning component;

[0033] Figure 8 is an exploded state schematic diagram of a part of a microscopic imaging device with a distance fine-tuning component;

[0034] Figure 9 is Figure 8 a combined state schematic diagram of a part of the microscopic imaging device with a distance fine-tuning component in DETAILED DESCRIPTION OF THE EMBODIMENTS

[0035] The following further details the content of the present application in conjunction with each drawing. It should be noted that the following is a description of the preferred embodiments of the present invention and does not constitute any limitation to the present invention. The description of the preferred embodiments of the present invention is only for the illustration of the general principles of the present invention. The numbers such as "first", "second", "A", and "B" involved in the present invention are only for the convenience of description and do not represent the sequence relationship in time or space. The combinations of letters and numbers such as "TA", "TB", and "H" involved in the present invention are only for the convenience of description, and the specific meanings are determined by the specific words they represent.

[0036] A large number of images are required for analysis. To improve the image acquisition efficiency, a dual-camera module form can be adopted. Usually, for the consistency of calculation, the two groups of camera modules can acquire images with the same fixed magnification of the microscopic imaging. However, in some cases, during the formed element analysis process, the image clarity of different targets is different at the same magnification. If a microscopic imaging device with the same magnification is used, the images of some targets are not clear enough. In order to better obtain clear images of different targets, the technical solution in the present application is designed.

[0037] As Figure 1 In an embodiment of a microscopic imaging device with a distance fine-tuning component, it includes a camera module A110, a support component 150, and a distance fine-tuning component A111; the support component 150 is used to mount and support the camera module A110 and the distance fine-tuning component A111.

[0038] As Figure 7 In an embodiment of a microscopic imaging device with a distance fine-tuning component, the distance fine-tuning component A includes a lens barrel B730, a lens barrel A720, and a directional guide rail 750. The lens barrel B730 and the lens barrel A720 include internal through holes, and the imaging optical path can pass through the above internal through holes; the camera module A710 is mechanically connected to the above lens barrel A720; the lens barrel A720 is sleeved on the lens barrel B720, and the lens barrel B720 and the lens barrel A710 are connected by threads. Under the action of the directional guide rail 750, the lens barrel A720 can move in a linear direction; during the rotation of the lens barrel B730, the lens barrel A720 is driven to move in a linear direction; the lens barrel A720 drives the camera module A710 to move in a linear direction to perform distance fine-tuning of the imaging of the camera module A710.

[0039] As Figure 7 In an embodiment of a microscopic imaging device with a distance fine-tuning component, the directional guide rail 750 includes a groove portion 752 and a directional guide rail portion 751, and the directional guide rail portion 751 can move in the groove portion 752 under the drive of an external force.

[0040] As Figure 2 In an embodiment of a microscopic imaging device with a distance fine-tuning component, it further includes a camera module B120 and a beam splitter A131; the imaging optical path is split by the beam splitter A131 into two optical paths, and the camera module A110 forms an image on one optical path; the camera module B120 forms an image on the other optical path. In an embodiment of a microscopic imaging device with a distance fine-tuning component not shown in some drawings, it further includes a distance fine-tuning component B; the distance fine-tuning component B includes a lens barrel B, a lens barrel A, and a directional guide rail. The lens barrel B and the lens barrel A include internal through holes, and the imaging optical path can pass through the above internal through holes; the camera module B is mechanically connected to the above lens barrel A; the lens barrel A is sleeved on the lens barrel B, and the lens barrel B and the lens barrel A are connected by threads. Under the action of the directional guide rail, the lens barrel A can move in a linear direction; during the rotation of the lens barrel B, the lens barrel A is driven to move in a linear direction; the lens barrel A drives the camera module B to move in a linear direction to perform distance fine-tuning of the imaging of the camera module B120.

[0041] As Figure 3, in an embodiment of a microscopic imaging device with a distance fine-tuning component, it further includes a beam splitter B161 and a marker light component 160; the beam splitter B161 splits an optical path into a marker optical path, and the marker light component 160 emits marker light, which forms a marker pattern on the detection target through the marker optical path. The marker pattern passes through the imaging optical path and is imaged by the camera module A110 or the camera module B120 to form a marker image. Figure 3 It further includes a lens module 360. The marker light is reflected by the optical path to the camera module A and the camera module B. Through the distance fine-tuning function, the imaging quality in the camera module A and the camera module B is compared to determine the position of the best focus plane. Through the distance adjustment, the imaging quality comparison between A and B is realized to determine the position of the best focus plane.

[0042] The imaging quality of the measured target and surrounding objects can be improved through the dual cameras and distance fine-tuning. That is, the camera B is fixed at the imaging distance of the best focus plane, and the camera A realizes the imaging quality of the surrounding objects of the measured target by fine-tuning the distance.

[0043] Such as Figures 4 to 6 , in an embodiment of a microscopic imaging device with a distance fine-tuning component, it includes a camera module A410, a support component 450, a distance fine-tuning component A411, a camera module B420, a distance fine-tuning component B421, a beam splitter A631, and a beam splitter B632; the support component 450 includes a marker light component mounting hole 451, and the marker light component is connected to the above-mentioned marker optical path through the mounting hole 451.

[0044] Such as Figures 4 to 6 , in an embodiment of a microscopic imaging device with a distance fine-tuning component, it further includes a lens module 460, and the lens module 460 includes a turntable 462 and at least two groups of lenses 461. The above-mentioned lenses 461 are installed on the above-mentioned turntable 460, and by rotating the turntable, different lenses are switched into the optical path.

[0045] Such as Figures 4 to 6 , in an embodiment of a microscopic imaging device with a distance fine-tuning component, the lens module 460 is connected in series with the beam splitter A631 and the camera module A410 in the vertical direction, and the distance fine-tuning component A411 is used to drive the camera module A410 to move in the vertical direction.

[0046] In an embodiment of a microscopic imaging device with a distance fine-tuning component not shown in some drawings, the lens module 460 is connected in series with the beam splitter A631 and the camera module B420 in the vertical direction, and the distance fine-tuning component A411 is used to drive the camera module A410 to move in the horizontal direction. That is, relative to Figures 4 to 6 the embodiment in

[0047] Such as Figures 4 to 6, in an embodiment of a microscopic imaging device with a distance fine-tuning component, the lens module 460, the beam splitter A 631, and the imaging module A 410 are connected in series in the vertical direction; the lens module 460 is connected in series with the imaging module B 420 in the horizontal direction through the beam splitter A 631, and the distance fine-tuning component B 421 is used to drive the imaging module B 420 to move in the horizontal direction.

[0048] As Figures 4 to 6 , in an embodiment of a microscopic imaging device with a distance fine-tuning component, the above-mentioned lens module 460 includes a motor A 463 and a gear set A 464. The gear set A 464 is respectively gear-connected to the motor A 463 and the above-mentioned turntable 462. The motor A 463 drives the turntable 462 to rotate through the gear set A 464. The above-mentioned lens module 460 further includes a position sensor 467, and the above-mentioned position sensor 467 is used to detect the position of the above-mentioned disk teeth.

[0049] As Figures 8 to 9 , in an embodiment of a microscopic imaging device with a distance fine-tuning component, the above-mentioned distance fine-tuning component A or the distance fine-tuning component B further includes a gear set B 823 and a motor B 821; the input end of the gear set B 823 is mechanically connected to the shaft of the motor B 821; the output end of the gear set B 823 is mechanically connected to the lens barrel B 822; the rotational output of the motor B 821 passes through the gear set B 823 to drive the lens barrel B 822 to rotate; when the lens barrel B 822 rotates, it drives the lens barrel A 811 to move up and down.

[0050] As Figures 8 to 9 , in an embodiment of a microscopic imaging device with a distance fine-tuning component, the distance fine-tuning component A or the distance fine-tuning component B further includes a position sensor 824, and the above-mentioned position sensor 824 is used to detect the position of the above-mentioned lens barrel A 811. The position sensor 824 is fixed through a mounting bracket 827; the mounting bracket 827 is arranged on the support component 850 above the lens barrel A 811. The reference numeral 812 in the figure is the imaging module A or the imaging module B.

[0051] As Figures 8 to 9 , in an embodiment of a microscopic imaging device with a distance fine-tuning component, a directional guide rail 830 is sleeved outside the lens barrel A 811. The directional guide rail 830 includes a groove portion 831 and a directional guide rail portion. The directional guide rail portion can move in the groove portion 831 under the drive of an external force. The directional guide rail portion is installed on the outer wall of the lens barrel A 811; it is not shown in the drawing. The motor B 821 drives the lens barrel B 822 to rotate through the gear set B 823; when the lens barrel B 822 rotates, it drives the lens barrel A 811 to move up and down along the groove portion 831. The directional guide rail 830 is also provided with a motor mounting hole 832 for accommodating the motor B 821. The above-mentioned component KA 820 includes a position sensor 824, and the above-mentioned position sensor 824 is used to detect the position of the above-mentioned lens barrel A 811.

[0052] The motor in this application can be a stepper motor, a servo motor, or other precision motors that can be precisely controlled. The imaging module A and the imaging module B include a CCD camera or other devices that can acquire magnified microscopic images.

[0053] A formed component detection device includes the above-mentioned microscopic imaging device with a distance fine-tuning component. It further includes a Z-axis moving component, which is fixedly connected to the microscopic imaging device with a distance fine-tuning component and is used to drive the microscopic imaging device with a distance fine-tuning component to move in the Z-axis direction.

[0054] Although the present invention is described and illustrated according to preferred embodiments and several alternative solutions, the invention is not limited by the specific descriptions in this specification. Other additional alternatives or equivalent components can also be used to practice the present invention.

Claims

1. A microscopic imaging device with a phase fine-tuning component, characterized in that: It includes a camera module A, a support component, and a distance fine-tuning component A; the support component is used for mounting support; The phase distance fine adjustment assembly A comprises a lens barrel B, a lens barrel A, and a directional guide rail, and the lens barrel B and the lens barrel A comprise an internal through hole, and the imaging light path can pass through the internal through hole; The camera module A is mechanically connected to the lens barrel A; Lens barrel A is sleeved on lens barrel B. Lens barrel B and lens barrel A are connected by threads. The directional guide rail is mechanically connected to lens barrel A. Under the action of the directional guide rail, lens barrel A can move in a straight line. During the rotation of lens barrel B, lens barrel A is driven to move in a straight line. Lens barrel A drives camera module A to move in a straight line.

2. The microscopic imaging device with a phase distance fine-tuning component according to claim 1, characterized in that: It also includes a camera module B and a beam splitter A; The imaging light path is split by the beam splitter A into two light paths. The camera module A forms an image on one light path, and the camera module B forms an image on the other light path.

3. The microscopic imaging device with a phase distance fine-tuning component according to claim 2, characterized in that: It also includes a distance fine-tuning component B; the distance fine-tuning component B includes a lens barrel B, a lens barrel A, and a directional guide rail, and the lens barrel B and the lens barrel A include an internal through hole, and the imaging light path can pass through the internal through hole; The camera module B is mechanically connected to the lens barrel A; Lens barrel A is sleeved on lens barrel B, which is connected to lens barrel A through threads, and a directional guide rail is mechanically connected to lens barrel A. Under the action of the directional guide rail, lens barrel A can move in a straight line. During the rotation of lens barrel B, lens barrel A is driven to move in a straight line. Lens barrel A drives camera module B to move in a straight line.

4. The microscopic imaging device with a phase distance fine-tuning component according to any one of claims 1 to 3, characterized in that: It also includes a beam splitter B and a marking light assembly; Beam splitter B splits a light path into a marking light path. The marking light assembly emits marking light, which forms a marking pattern on the detection target through the marking light path. The marking pattern passes through the imaging light path and is imaged in the camera module A and / or the camera module B to form a marking image.

5. The microscopic imaging device with a phase distance fine-tuning component according to claim 4, characterized in that: The supporting assembly comprises a marking light assembly mounting hole, and the marking light assembly is connected to the marking light path through the mounting hole.

6. The microscopic imaging device with a phase distance fine-tuning component according to any one of claims 1 to 3, characterized in that: It also includes a lens module, which includes a turntable and at least two groups of lenses. The lenses are mounted on the turntable, and different lenses are switched to the light path when the turntable is rotated.

7. The microscopic imaging device with a phase distance fine-tuning component according to claim 2, characterized in that: It also includes a lens module, which is connected in series with the beam splitter A and the camera module A in the vertical direction, and the distance fine-tuning component A is used to drive the camera module A to move in the vertical direction.

8. The microscopic imaging device with a phase distance fine-tuning component according to claim 2, characterized in that: It also includes a lens module, which is connected in series with the beam splitter A and the camera module B in the vertical direction, and the distance fine-tuning component A is used to drive the camera module A to move in the horizontal direction.

9. The microscopic imaging device with a phase distance fine adjustment component according to claim 6, characterized in that: The lens module includes a motor A and a gear set A. The gear set A is connected to the motor A and the turntable gear respectively. The motor A drives the turntable to rotate through the gear set A.

10. The microscopic imaging device with a phase distance fine adjustment component according to claim 9, characterized in that: The lens module further includes a position sensor, and the position sensor is used to detect the position of the teeth of the turntable gear.

11. The microscopic imaging device with a phase distance fine-tuning component according to any one of claims 1 to 3, characterized in that: The phase distance fine adjustment component A or the phase distance fine adjustment component B also includes a gear set B and a motor B; The input end of gear set B is mechanically connected to the shaft of motor B; The output end of gear set B is mechanically connected to lens barrel B; The rotation output of motor B passes through gear set B to drive lens barrel B to rotate; The lens barrel B rotates, driving the lens barrel A to move up and down.

12. The microscopic imaging device with a phase distance fine adjustment component according to claim 11, characterized in that: The phase distance fine adjustment component A or the phase distance fine adjustment component B further includes a position sensor, and the position sensor is used to detect the position of the lens barrel A.

13. A shaped component detection device, characterized in that: A microscopic imaging device with a phase distance fine-tuning component comprising any one of claims 1 to 10.

14. The shaped component detection device according to claim 13, characterized in that: It also includes a Z-axis moving component, which is fixedly connected to the microscopic imaging device with the phase fine-tuning component and is used to drive the microscopic imaging device with the phase fine-tuning component to move in the Z-axis direction.