Multifunctional administration device for nasal cavity of mouse
By designing a multifunctional mouse nasal doser, the mice are fixed with clamps and positioners, and the lifting member adjusts the cannula insertion angle to achieve quantitative heating and stable drug delivery, the inconvenience problem during the nasal dosing of mice is solved and the stability and convenience of operation are improved.
Patent Information
- Application Number
- CN202421666093.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-15
- Publication Date
- 2025-07-08
- Estimated Expiration
- 2034-07-15
AI Technical Summary
When nasal administration of mice, the activity of the mice makes the administration process inconvenient.
A multifunctional drug delivery device for the nasal cavity of mice is designed, including a micropump, a micropillar storage device, a heating element, a clamp, a positioning element and a lifting element. The mouse is fixed by the clamp, the positioning element locates the mouse's neck and mouth, and the lifting element adjusts the cannula insertion angle to realize quantitative heating of the drug liquid and enter the nasal cavity.
It improves the stability and convenience of drug administration, heats the drug solution to prevent discomfort in mice, and enhances the stability and versatility of the drug administration process.
Smart Images
Figure CN223068645U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of machining, and more specifically, to a multi-functional nasal cavity medicator for mice. Background Art
[0002] The new biological material of the nasal cavity medicator has high safety, is convenient and fast, can administer drugs quantitatively, and has dual functions of prevention and repair treatment. It is a leading foreign technology, with selected components nationwide, no hormones, no dependence, and no side effects. Nasal preparations are a class of preparations directly used in the nasal cavity to exert local or systemic therapeutic effects, and have the advantages of rapid absorption, quick onset, avoidance of the first-pass effect of the liver, high bioavailability, and bypassing the blood-brain barrier to achieve brain targeting.
[0003] Currently, during the process of nasal administration to mice, it often requires staff to hold the mice. Since the activities of mice are very inconvenient during nasal administration, it is necessary to propose a multi-functional nasal cavity medicator for mice to solve the above problems. Summary of the Utility Model
[0004] To make up for the above deficiencies, the utility model provides a multi-functional nasal cavity medicator for mice, aiming to improve the problem that during the process of nasal administration to mice, it often requires staff to hold the mice, and the activities of mice are very inconvenient during nasal administration.
[0005] The utility model is implemented as follows:
[0006] The utility model provides a multi-functional nasal cavity medicator for mice, including a drug administration structure and a positioning drug delivery structure.
[0007] The drug administration structure includes a micro pump and a micro drug reservoir, and the micro drug reservoir is installed at the drug pushing position of the micro pump. The positioning drug delivery structure includes a fixing plate, a supporting plate, a clamping member, a positioning member, and a lifting member. The fixing plate is fixed on the top surface of the micro pump, the supporting plate is fixed on the top surface of the fixing plate, a placement groove is formed on the top surface of the supporting plate, the clamping member is installed on the supporting plate, the positioning member is fixed on the clamping member, the lifting member is installed at one end of the fixing plate, and a drug delivery member is installed between the lifting member and the micro drug reservoir.
[0008] In one embodiment of the utility model, a heating member is installed on the micro pump. The heating member includes a first heating pad, a second heating pad, and a fixing block. The first heating pad is embedded in the micro pump. Arc-shaped grooves are formed on the surfaces of the second heating pad and the first heating pad. The fixing blocks are fixedly spaced on the surface of the micro pump, and the second heating pad is rotatably connected between the fixing blocks through a first connecting block.
[0009] In an embodiment of the present utility model, a first magnet block is embedded in the first heating pad, a second magnet block matching the first magnet block is embedded in the second heating pad, and the first magnet block and the second magnet block are adsorbed and fixed.
[0010] In an embodiment of the present utility model, the clamping member includes a first threaded rod and a first limiting rod. One end of the first threaded rod is rotatably connected to the support plate, a lifting plate is threadedly penetrated through the first threaded rod, a clamping plate is fixedly spaced on one side of the lifting plate, the first limiting rod slidably penetrates through the lifting plate, and the end of the first limiting rod is fixed to the support plate.
[0011] In an embodiment of the present utility model, the positioning member includes a frustum-shaped clamping sleeve and a second connecting block. The second connecting block is fixed to one side of the frustum-shaped clamping sleeve, limiting plates are fixed to both sides of the second connecting block, and the second connecting block is fixed to one side of the clamping plate.
[0012] In an embodiment of the present utility model, the lifting member includes a second threaded rod and a second limiting rod. One end of the second threaded rod is rotatably connected to the fixing plate, a movable plate is threadedly penetrated through the second threaded rod, the second limiting rod slidably penetrates through the movable plate, the end of the second limiting rod is fixed to the fixing plate, and a notch is formed at one end of the movable plate.
[0013] In an embodiment of the present utility model, the medicine delivery member includes a connecting pipe and a fixing pipe. The fixing pipe is rotatably connected inside the notch, two inserting pipes are fixedly communicated at one end of the fixing pipe, one end of the connecting pipe is fixedly communicated with the fixing pipe, and the other end of the connecting pipe is sleeved on the output end of the micro medicine storage device.
[0014] The beneficial effects of the present utility model are as follows: A multi-functional nasal cavity medicine delivery device for mice obtained by the above design of the present utility model, when in use, the mouse is clamped and fixed in the placement groove through the clamping member, and at the same time, the limiting plates are clamped on both sides of the mouse's neck and the frustum-shaped clamping sleeve is clamped on the mouse's mouth for positioning and exposing the nostrils. At this time, the movable plate is moved downward through the lifting member. During the downward movement, the fixing pipe is manually rotated to adjust the insertion angle of the inserting pipe so that the inserting pipe is inserted into the nasal cavity of the mouse. Then, the micro pump works to push the micro medicine storage device, so that the liquid medicine in the micro medicine storage device enters the nasal cavity of the mouse through the connecting pipe, the fixing pipe and the inserting pipe. In this way, the liquid medicine can be conveniently heated during the medicine delivery process, and at the same time, the mouse can be positioned and fixed, improving the stability of medicine delivery and making it more convenient to use with more diverse functions. Description of the Drawings
[0015] To more clearly illustrate the technical solutions of the embodiments of the present utility model, the following will briefly introduce the attached drawings required for the embodiments. It should be understood that the following attached drawings only show certain embodiments of the present utility model, and thus should not be regarded as a limitation of the scope. For those of ordinary skill in the art, without creative efforts, other relevant attached drawings can also be obtained based on these attached drawings.
[0016] Figure 1 It is a schematic structural diagram of a multi-functional nasal cavity drug delivery device for mice provided by the embodiments of the present utility model;
[0017] Figure 2 It is a schematic structural diagram of a heating element of a multi-functional nasal cavity drug delivery device for mice provided by the embodiments of the present utility model;
[0018] Figure 3 It is a schematic structural diagram of a positioning drug delivery structure of a multi-functional nasal cavity drug delivery device for mice provided by the embodiments of the present utility model;
[0019] Figure 4 It is a schematic structural diagram of a positioning member of a multi-functional nasal cavity drug delivery device for mice provided by the embodiments of the present utility model;
[0020] Figure 5 It is a schematic structural diagram of a lifting member of a multi-functional nasal cavity drug delivery device for mice provided by the embodiments of the present utility model.
[0021] In the figure: 100 - drug delivery structure; 110 - micro pump; 120 - micro drug reservoir; 130 - heating element; 131 - first heating pad; 1311 - first magnet block; 132 - second heating pad; 1321 - second magnet block; 133 - arc groove; 134 - first connecting block; 135 - fixing block; 200 - positioning drug delivery structure; 210 - fixing plate; 220 - supporting plate; 221 - placing groove; 230 - clamping member; 231 - first threaded rod; 232 - lifting plate; 233 - clamping plate; 234 - first limiting rod; 240 - positioning member; 241 - table-shaped card sleeve; 242 - second connecting block; 243 - limiting plate; 250 - lifting member; 251 - second threaded rod; 252 - movable plate; 253 - second limiting rod; 254 - notch; 260 - drug delivery member; 261 - connecting pipe; 262 - fixing pipe; 263 - inserting pipe. Specific embodiments
[0022] To make the objectives, technical solutions, and advantages of the embodiments of the present utility model clearer, the technical solutions in the embodiments of the present utility model will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present utility model. Apparently, the described embodiments are part of the embodiments of the present utility model, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model. Embodiment
[0023] Please refer to Figures 1 - 5 , the present utility model provides a technical solution: a multi-functional nasal drug delivery device for mice, including a drug delivery structure 100 and a positioning drug delivery structure 200.
[0024] Please refer to Figure 1 and Figure 2 , the drug delivery structure 100 includes a micro pump 110 and a micro drug reservoir 120, and the micro drug reservoir 120 is installed at the drug pushing position of the micro pump 110.
[0025] A heating element 130 is installed on the micro pump 110. The heating element 130 includes a first heating pad 131, a second heating pad 132, and a fixing block 135. The first heating pad 131 is embedded on the micro pump 110. Arc-shaped grooves 133 are provided on the surfaces of both the second heating pad 132 and the first heating pad 131. The fixing block 135 is fixedly spaced on the surface of the micro pump 110. The second heating pad 132 is rotatably connected between the fixing blocks 135 through a first connecting block 134. Here, the heating element 130 can preheat the liquid medicine inside the connecting tube 261, so as to prevent the discomfort of the mice caused by the relatively cold liquid medicine when input into the nasal cavity of the mice, and increase the functionality of the drug delivery device. A first magnet block 1311 is embedded on the first heating pad 131, and a second magnet block 1321 matching the first magnet block 1311 is embedded on the second heating pad 132. The first magnet block 1311 and the second magnet block 1321 are adsorbed and fixed. Here, the first magnet block 1311 and the second magnet block 1321 can be used to conveniently clamp and fix the connecting tube 261.
[0026] Please refer to Figures 1 - 5 , the positioning drug delivery structure 200 includes a fixing plate 210, a supporting plate 220, a clamping member 230, a positioning member 240, and a lifting member 250. The fixing plate 210 is fixed on the top surface of the micro pump 110, the supporting plate 220 is fixed on the top surface of the fixing plate 210. A placement groove 221 is provided on the top surface of the supporting plate 220. The clamping member 230 is installed on the supporting plate 220. The positioning member 240 is fixed on the clamping member 230. The lifting member 250 is installed at one end of the fixing plate 210. A drug delivery member 260 is installed between the lifting member 250 and the micro drug reservoir 120.
[0027] The clamping member 230 includes a first threaded rod 231 and a first limiting rod 234. One end of the first threaded rod 231 is rotatably connected to the support plate 220. A lifting plate 232 is threadedly penetrated through the first threaded rod 231. A clamping plate 233 is fixedly spaced on one side of the lifting plate 232. The first limiting rod 234 slidably penetrates through the lifting plate 232, and the end of the first limiting rod 234 is fixed to the support plate 220. Here, a knob is key-connected to the upper end of the first threaded rod 231 for facilitating the rotation of the first threaded rod 231. Here, by rotating the first threaded rod 231, the lifting plate 232 moves upward under the action of the first limiting rod 234 to open the clamping plate 233. The positioning member 240 includes a frustum-shaped bushing 241 and a second connecting block 242. The second connecting block 242 is fixed to one side of the frustum-shaped bushing 241. Limiting plates 243 are fixed on both sides of the second connecting block 242. The second connecting block 242 is fixed to one side of the clamping plate 233. Here, the limiting plates 243 can position the neck of the mouse, and then the frustum-shaped bushing 241 is sleeved on the nose of the mouse, so as to maintain the stability of the mouse during the drug administration process.
[0028] The lifting member 250 includes a second threaded rod 251 and a second limiting rod 253. One end of the second threaded rod 251 is rotatably connected to the fixing plate 210. A movable plate 252 is threadedly penetrated through the second threaded rod 251. The second limiting rod 253 slidably penetrates through the movable plate 252, and the end of the second limiting rod 253 is fixed to the fixing plate 210. A notch 254 is formed at one end of the movable plate 252. The medicine delivery member 260 includes a connecting pipe 261 and a fixing pipe 262. The fixing pipe 262 is rotatably connected inside the notch 254. Two intubation tubes 263 are fixedly communicated at one end of the fixing pipe 262. Here, the intubation tubes 263 are located directly above the frustum-shaped bushing 241. One end of the connecting pipe 261 is fixedly communicated with the fixing pipe 262. The other end of the connecting pipe 261 is sleeved on the output end of the micro medicine storage device 120. Here, a knob is also key-connected to the end of the second threaded rod 251. By rotating the second threaded rod 251 through the knob, the movable plate 252 drives the fixing pipe 262 to move up and down under the action of the second limiting rod 253, and inserts the intubation tubes 263 into the nasal cavity of the mouse. The medicine delivery member 260 includes a connecting pipe 261 and a fixing pipe 262. The fixing pipe 262 is rotatably connected inside the notch 254. Two intubation tubes 263 are fixedly communicated at one end of the fixing pipe 262. One end of the connecting pipe 261 is fixedly communicated with the fixing pipe 262. The other end of the connecting pipe 261 is sleeved on the output end of the micro medicine storage device 120. Here, the connecting pipe 261, the fixing pipe 262 and the intubation tubes 263 play a role in guiding the flow.
[0029] Specifically, the working principle of the multi-functional nasal drug delivery device for mice is as follows: during use, by rotating the first threaded rod 231, the lifting plate 232 moves upward under the action of the first limiting rod 234 to open the clamping plate 233, and then the mouse is placed in the placement groove 221. At this time, rotate the first threaded rod 231 in the reverse direction to make the lifting plate 232 move downward and clamp the mouse through the clamping plate 233. At the same time, the limiting plate 243 is stuck on both sides of the mouse's neck, and the trapezoidal sleeve 241 is stuck on the mouse's mouth for positioning and exposing the nostrils. At this time, the connecting pipe 261 is connected to the output end of the micro drug reservoir 120, and the connecting pipe 261 is placed in the arc-shaped groove 133 and heated by the heating element 130. At this time, rotate the second threaded rod 251 to make the movable plate 252 move downward. During the downward movement, manually rotate the fixed pipe 262 to adjust the insertion angle of the intubation tube 263 so that the intubation tube 263 is inserted into the nasal cavity of the mouse. Then, the micro pump 110 works to push the micro drug reservoir 120, so that the liquid medicine in the micro drug reservoir 120 enters the nasal cavity of the mouse through the connecting pipe 261, the fixed pipe 262, and the intubation tube 263. In this way, the liquid medicine can be conveniently heated during the drug delivery process, and at the same time, the mouse can be positioned and fixed, improving the stability of drug delivery and making it more convenient to use with more diverse functions.
[0030] It should be noted that the specific model and specification of the micro pump 110 need to be selected according to the actual specifications of the device, etc. The specific selection calculation method adopts the existing technology in this field, so it will not be elaborated in detail.
[0031] The power supply and principle of the micro pump 110 are clear to those skilled in the art and will not be described in detail here.
[0032] The above are only the preferred embodiments of the present invention and are not used to limit the present invention. For those skilled in the art, the present invention can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. A multi-functional nasal drug delivery device for mice, comprising a drug delivery structure (100) and a positioning drug delivery structure (200) mounted on the drug delivery structure (100), characterized in that the drug delivery structure (100) includes a micro pump (110) and a micro drug reservoir (120), and the micro drug reservoir (120) is mounted at the drug pushing position of the micro pump (110); the positioning drug delivery structure (200) includes a fixing plate (210), a supporting plate (220), a clamping member (230), a positioning member (240) and a lifting member (250). The fixing plate (210) is fixed on the top surface of the micro pump (110), the supporting plate (220) is fixed on the top surface of the fixing plate (210), a placing groove (221) is formed on the top surface of the supporting plate (220), the clamping member (230) is mounted on the supporting plate (220), the positioning member (240) is fixed on the clamping member (230), the lifting member (250) is mounted at one end of the fixing plate (210), and a drug delivery member (260) is mounted between the lifting member (250) and the micro drug reservoir (120).
2. The multifunctional nasal drug delivery device for mice according to claim 1, wherein, A heating member (130) is mounted on the micro pump (110). The heating member (130) includes a first heating pad (131), a second heating pad (132) and a fixing block (135). The first heating pad (131) is embedded in the micro pump (110), arc-shaped grooves (133) are formed on the surfaces of the second heating pad (132) and the first heating pad (131), the fixing blocks (135) are fixedly spaced on the surface of the micro pump (110), and the second heating pad (132) is rotatably connected between the fixing blocks (135) through a first connecting block (134).
3. The multifunctional nasal drug delivery device for mice according to claim 2, characterized in that, A first magnet block (1311) is embedded in the first heating pad (131), a second magnet block (1321) matching the first magnet block (1311) is embedded in the second heating pad (132), and the first magnet block (1311) and the second magnet block (1321) are adsorbed and fixed.
4. The multi-functional nasal cavity drug delivery device for mice according to claim 1, characterized in that, The clamping member (230) includes a first threaded rod (231) and a first limiting rod (234). One end of the first threaded rod (231) is rotatably connected to the supporting plate (220), a lifting plate (232) is threadedly penetrated through the first threaded rod (231), clamping plates (233) are fixedly spaced on one side of the lifting plate (232), the first limiting rod (234) slidably penetrates through the lifting plate (232), and the end of the first limiting rod (234) is fixed to the supporting plate (220).
5. The multi-functional nasal drug delivery device for mice according to claim 4, characterized in that, The positioning member (240) includes a frustum-shaped sleeve (241) and a second connecting block (242). The second connecting block (242) is fixed on one side of the frustum-shaped sleeve (241), limiting plates (243) are fixed on both sides of the second connecting block (242), and the second connecting block (242) is fixed to one side of the clamping plate (233).
6. The multifunctional nasal drug delivery device for mice according to claim 1, wherein, The lifting member (250) includes a second threaded rod (251) and a second limiting rod (253). One end of the second threaded rod (251) is rotatably connected to the fixed plate (210). A movable plate (252) is threadedly penetrated through the second threaded rod (251). The second limiting rod (253) slidably penetrates through the movable plate (252). The end of the second limiting rod (253) is fixed to the fixed plate (210). An opening (254) is formed at one end of the movable plate (252).
7. The multifunctional nasal drug delivery device for mice according to claim 6, wherein, The medicine delivery member (260) includes a connecting pipe (261) and a fixed pipe (262). The fixed pipe (262) is rotatably connected to the inside of the opening (254). Two insertion pipes (263) are fixedly communicated at one end of the fixed pipe (262). One end of the connecting pipe (261) is fixedly communicated with the fixed pipe (262). The other end of the connecting pipe (261) is sleeved on the output end of the micro medicine reservoir (120).