Sample preparation device for quantitative detection

By combining the design of the quantization bottle and sealing assembly, the existing devices have solved the problems of large errors and cumbersome operations in quantitative detection, and the accuracy and accuracy of the preparation of the liquid to be tested is achieved, reducing the detection cost.

CN223077994UActive Publication Date: 2025-07-08BEIJING YAN SPACE BIOTECHNOLOGY CO LTD +3
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Patent Information

Application Number
CN202421218316.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-30
Publication Date
2025-07-08
Estimated Expiration
2034-05-30

AI Technical Summary

Technical Problem

The existing quantitative detection devices have large errors, poor precision, and cumbersome operations when preparing the liquid to be tested, which increases the cost of equipment usage. Especially when extraction is required and the liquid to be tested is located in the lower layer, there are solution losses and detection errors during the transfer process.

Method used

It provides a sample preparation device for quantitative detection, combining a dosage bottle and a sealing assembly, including a bottle mouth, a bottle body, a connecting port, a main body, a liquid outlet pipe and a constant pressure pipe. The accurate addition and extraction of the solution is achieved through the seal and a liquid outlet valve, simplifying the operation process and reducing costs.

Benefits of technology

The accuracy and accuracy of the liquid to be tested is achieved, the preparation steps are simplified, the detection cost is reduced, the solution loss and error are avoided, and the detection reproducibility is improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a sample preparation device for quantitative detection. The sample preparation device for quantitative detection comprises a quantitative bottle and a sealing assembly, the quantitative bottle comprises a bottle opening and a bottle body; the sealing assembly comprises a connector, a main body and a liquid outlet pipe; the connector, the main body and the liquid outlet pipe are connected into a whole; the connecting opening is detachably connected with the bottle opening in a sealing manner; an air vent is formed in the main body, a constant-pressure pipe is arranged in the direction from the air vent to the connecting port in an extending mode, and the constant-pressure pipe penetrates through the connecting port; the sealing assembly further comprises a sealing piece used for sealing the ventilation opening. And a liquid outlet valve is arranged on the liquid outlet pipe. The sample preparation device for quantitative detection has the effects of quantifying the volume of the solution, the reaction bottle and the separating funnel, and can be suitable for preparing various to-be-detected solutions for quantitative detection. The accuracy and precision of the test result are ensured, the preparation steps of the to-be-detected liquid are simplified, and the detection cost is reduced.
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Description

Technical Field

[0001] The utility model relates to the field of laboratory instrument and equipment, in particular to a sample preparation device for quantitative detection. Background Art

[0002] At present, in the field of quantitative analysis of compounds, in the process of quantitative testing, the test solution to be measured may need to be sequentially added with a variety of solvents. In the process of preparing the test solution to be measured, each solvent needs to be sequentially added by devices such as pipettes and pipettes to achieve the purpose of dissolution or completion of a micro-reaction (derivatization). Because when different solvents are mixed, the total volume is slightly less than the sum of the volumes of each solvent, this may cause problems such as inaccurate detection results of solute concentration and poor precision. At the same time, the pipette or pipette needs to be regularly calibrated and rinsed multiple times during use, and the operation is relatively cumbersome, increasing the use cost of the equipment. For example, a certain compound has no response or a low response value in the detection method, and a derivatization-extraction method needs to be used to prepare the test solution to be measured. In this process, different reagents need to be added in small amounts and multiple times to complete the derivatization process. Adding reagents multiple times is likely to cause deviation of the total volume, thereby affecting the detection results. As Figure 1 Shown in the traditional stoppered graduated cylinder can solve the above-mentioned problem of large error, but when dealing with the experiment where extraction is required and the test solution to be measured is the lower-layer solution, one way is to directly suck the lower-layer solution with a pipette, and there is a risk of contamination during the sucking process as it passes through the upper-layer solution; another way requires a separating funnel to obtain the lower-layer solution, and there is a problem of solution loss during the transfer process, which will not only further increase the detection error, make the operation more cumbersome, but also increase the procurement cost.

[0003] Therefore, there is an urgent need in the art for a sample preparation device for the test solution to be measured, which is suitable for different types of quantitative detection, not only has ideal detection accuracy and precision, but is also easy to operate and reduces the detection cost. Summary of the Utility Model

[0004] The technical problem to be solved by this application is to overcome the defects that when the existing device prepares the test solution for quantitative detection, there are large errors, poor precision, and multiple devices are required to jointly complete the preparation of the test solution. For example, for the detection that requires extraction and the test solution to be measured is in the lower layer, at least devices such as pipettes or pipettes, reaction flasks, separating funnels, and glass rods are required, which not only increases the use cost of the equipment, but also makes the operation cumbersome, time-consuming, and laborious. Based on the above defects of the existing equipment, the utility model provides a sample preparation device for quantitative detection. The sample preparation device for quantitative detection in this application simultaneously combines the functions of quantitatively measuring the solution volume, reaction flask, and separating funnel, and can be applied to the preparation of test solutions for various quantitative detections. It not only ensures the accuracy and precision of the test results, but also simplifies the preparation steps of the test solution and reduces the detection cost.

[0005] This application solves the above technical problems through the following technical solutions.

[0006] The present application provides a sample preparation device for quantitative detection, including a quantitative bottle and a sealing assembly; the quantitative bottle includes a bottle mouth and a bottle body; the sealing assembly includes a connection port, a main body, and a liquid outlet pipe; the connection port, the main body, and the liquid outlet pipe are integrated as a whole; the connection port and the bottle mouth are detachably and sealingly connected; an air vent is provided on the main body, and a constant pressure pipe extends from the air vent towards the connection port direction and passes through the connection port; the sealing assembly further includes a sealing member for sealing the air vent; a liquid outlet valve is provided on the liquid outlet pipe.

[0007] In some embodiments, the shape of the bottle body is a hollow cylinder, such as a hollow circular cylinder or a hollow cuboid.

[0008] In some embodiments, the material of the bottle body is glass or polytetrafluoroethylene.

[0009] In some embodiments, the color of the bottle body is transparent or brown.

[0010] In some embodiments, volume scales are provided on the bottle body. According to the convention in the art, the volume scale value at the bottommost layer for loading liquid in the sample preparation device for quantitative detection is "0", and the volume scale values increase gradually from bottom to top.

[0011] In some embodiments, at least one cavity is provided on the bottle body.

[0012] In a preferred embodiment, the cavity is provided in the middle part or the lower part of the bottle body.

[0013] In a preferred embodiment, volume scales are provided on the cavity. The volume scale value on the cavity is the volume corresponding to the space from the bottommost layer for loading liquid in the sample preparation device for quantitative detection to this volume scale line.

[0014] In a preferred embodiment, the shape of the cavity is spherical, ellipsoidal, conical or pear-shaped.

[0015] In a more preferred embodiment, at least one cavity is provided in the middle part of the bottle body, and volume scales are provided on the bottle body below the cavity and on the bottle body above the cavity.

[0016] In some embodiments, a base is provided below the bottle body.

[0017] In a preferred embodiment, the shape of the base is circular or square.

[0018] In some embodiments, the sealing assembly is selected from a sealing cap or a sealing plug.

[0019] In some embodiments, the sealing connection mode between the connection port and the bottle mouth is selected from screw thread, bayonet, ground joint or sealing ring.

[0020] In some embodiments, the sample preparation device for quantitative detection further includes an adapter, and the connection port and the bottle mouth are detachably and sealingly connected through the adapter. When the sizes of the connection port and the bottle mouth do not match and they cannot be directly and sealingly connected, an indirect sealing connection can be achieved through the adapter.

[0021] In some embodiments, the connection port, the main body and the liquid outlet pipe are integrally formed or detachably and sealingly connected as a whole.

[0022] In some embodiments, the main body is a cavity structure.

[0023] In some embodiments, the main body is conical, cylindrical, or cylindrical at one end close to the connection port and conical at one end close to the liquid outlet pipe.

[0024] In some embodiments, the constant pressure pipe and the ventilation port are integrally formed, fixedly connected or detachably and sealingly connected.

[0025] In a preferred embodiment, a first connection part extends from the ventilation port towards the connection port. The first connection part is integrally formed with the ventilation port, and the constant pressure pipe is detachably and sealingly connected to the first connection part.

[0026] In a more preferred embodiment, the sealing connection mode between the constant pressure pipe and the first connection part is screw thread, bayonet, ground joint or sealing ring.

[0027] In some embodiments, the sealing connection mode between the sealing member and the ventilation port is screw thread, bayonet, ground joint or sealing ring.

[0028] In some embodiments, the sealing member is a sealing plug or a sealing cover.

[0029] In a preferred embodiment, the sealing member is a sealing plug, which is inserted into the ventilation port to seal the ventilation port.

[0030] In another preferred embodiment, a second connection part extends from the ventilation port in a direction away from the connection port. The sealing member is detachably and sealingly connected to the second connection part. The second connection part is communicated with the constant pressure pipe.

[0031] In some embodiments, after the quantitative bottle and the sealing assembly are assembled, the constant pressure pipe extends into the quantitative bottle.

[0032] In some embodiments, the length of the constant pressure tube can be conventionally selected according to the volume of the liquid in the metering bottle, ensuring that when the sample preparation device for quantitative detection is inverted, the end of the constant pressure tube close to the bottom of the metering bottle is above the liquid level.

[0033] In a preferred embodiment, the constant pressure tube extends to the bottom of the metering bottle.

[0034] In some embodiments, the liquid outlet valve is a stopcock valve.

[0035] In some embodiments, a drainage bevel is provided at the end of the liquid outlet tube away from the main body.

[0036] In some embodiments, the sample preparation device for quantitative detection further includes a connecting clip for tightly connecting and fixing the connection port and the bottle mouth together.

[0037] On the basis of conforming to the common knowledge in the art, the above preferred conditions can be combined arbitrarily to obtain various preferred examples of the present application.

[0038] The reagents and raw materials used in the present application are all commercially available.

[0039] The positive and progressive effects of the present application are as follows: The present application provides a sample preparation device for quantitative detection that simultaneously combines the functions of a volumetric solution, a reaction flask, and a separatory funnel, and can be applied to the preparation of test solutions for various quantitative detections. It not only ensures the accuracy and precision of the test results, but also simplifies the preparation steps of the test solution and reduces the detection cost. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] Figure 1 is a schematic structural diagram of an existing stoppered graduated cylinder;

[0041] Figure 2 is a three-dimensional structural diagram of the sample preparation device for quantitative detection according to Embodiment 1 of the present invention;

[0042] Figure 3 is a sectional view of the sample preparation device for quantitative detection according to Embodiment 1 of the present invention along the height direction;

[0043] Figure 4 is a three-dimensional structural diagram of the sealing assembly in Embodiment 1 of the present invention;

[0044] Figure 5 is a schematic structural diagram of the metering bottle in Embodiment 1 of the present invention;

[0045] Figure 6 is a sectional view of the sealing assembly along the height direction in an exemplary embodiment of the present invention;

[0046] Figure 7 is a schematic structural diagram of the metering bottle in an exemplary embodiment of the present invention;

[0047] Figure 8 This is a schematic structural diagram of a metering bottle in an exemplary embodiment of the present utility model;

[0048] Figure 9 This is a schematic structural diagram of a metering bottle in an exemplary embodiment of the present utility model;

[0049] Figure 10 This is a sectional view of the sealing assembly along the height direction in an exemplary embodiment of the present utility model.

[0050] Reference numerals

[0051] Metering bottle 1, bottle mouth 11, bottle body 12, cavity 121, volume scale 13, base 14;

[0052] Sealing assembly 2, connection port 21, main body 22, liquid outlet pipe 23, ventilation port 24, constant pressure pipe 25, seal 26, liquid outlet valve 27, first connection part 28, second connection part 29;

[0053] Connection clip 3. Detailed implementation manners

[0054] The present application will be further described below by way of embodiments, but the present application is not limited to the scope of the described embodiments. For the experimental methods without specific conditions noted in the following embodiments, they are carried out according to conventional methods and conditions, or selected according to the product specifications.

[0055] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by terms such as "upper", "lower", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as a limitation to the present utility model.

[0056] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the term "connection" should be understood in a broad sense. For example, it can be a fixed connection or a detachable connection; it can be a mechanical connection or an adhesive connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the internal communication of two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0057] The technical solution of the present utility model will be clearly and completely described below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present utility model, rather than all of them. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0058] Embodiment 1

[0059] The following is combined with Figures 2 to 5 and specific embodiments to introduce the sample preparation device for quantitative detection provided by the present utility model, which includes a quantitative bottle 1 and a sealing assembly 2; the quantitative bottle 1 includes a bottle mouth 11 and a bottle body 12; the sealing assembly 2 includes a connection port 21, a main body 22 and a liquid outlet pipe 23; the connection port 21, the main body 22 and the liquid outlet pipe 23 are integrally formed; the connection port 21 and the bottle mouth 11 are detachably and sealingly connected; a ventilation port 24 is provided on the main body 22, and a constant pressure pipe 25 extends from the ventilation port 24 towards the connection port 21, and the constant pressure pipe 25 passes through the connection port 21; the sealing assembly 2 further includes a sealing member 26 for sealing the ventilation port 24; a liquid outlet valve 27 is provided on the liquid outlet pipe 23.

[0060] When performing quantitative detection of compounds that require complex pretreatment, during the mixing process of different solvents, the total volume is slightly less than the sum of the volumes of each solvent, which may cause problems such as inaccurate detection results of solute concentration and poor precision. At the same time, during the use of pipettes or pipette tubes, processes such as regular calibration and multiple rinsing are required, which is relatively cumbersome and increases the use cost of equipment. For detections where extraction is required and the density of the sample to be measured is large and the sample to be measured is in the lower layer, a separating funnel is also needed. Due to the problem of solution residue during the transfer process, it will not only increase the detection error, but also require additional equipment such as a separating funnel, increasing the detection cost and being cumbersome to operate. After assembling the quantitative bottle 1 with the above-mentioned specific-structured sealing assembly 2, pretreatment operations are carried out inside the quantitative bottle 1, and the amount of sample added is based on the volume scale on the quantitative bottle 1. By aligning with the scale line (looking horizontally, the liquid level is tangent to the scale line), the solvent is accurately and quantitatively added; with this design, the preparation method of the sample to be measured can be unified, avoiding the situation of randomly changing the diluent according to the ratio during the quantification process, and improving the reproducibility of the detection. By using the sealing assembly 2 with a constant pressure pipe 25, the lower-layer sample to be measured with a large density can be obtained without the assistance of a separating funnel, which not only solves the problem of solution loss during the liquid transfer process, but also simplifies the experimental operation and reduces the detection cost.

[0061] In this embodiment, the shape of the bottle body 12 is a hollow cylinder. In other embodiments, the shape of the bottle body 12 can also be a hollow cuboid.

[0062] In this embodiment, a cavity 121 is provided in the middle of the bottle body 12. For the sample that needs to be diluted or extracted before detection after pre-treatment, the cavity 121 is provided on the bottle body 12 to achieve capacity expansion and reduce the height of the bottle body 12. In addition, the cavity 121 is also conducive to the full mixing of the composite solution.

[0063] In other embodiments, the number of the cavities 121 may be more than one, for example, two (see Figure 9 ), 3, 4 or more. The cavities 121 can also be arranged at different positions of the bottle body 12 according to actual needs. For example, the cavities 121 of appropriate number and volume can be arranged at the required positions according to the ratio of each reaction liquid, the ratio of the reaction liquid to the diluent, or the ratio of the reaction liquid to the extraction liquid.

[0064] In this embodiment, the cavity 121, the bottle body 12 above the cavity 121, and the bottle body 12 below the cavity 121 are all provided with volume scales 13. The value of the volume scale 13 on the bottom surface of the bottle body 12 is "0", and the volume scale values ​​gradually increase from bottom to top.

[0065] In other embodiments, if the cavity 121 is only used to store liquid and does not need to play a quantitative role, the volume scale 13 may not be set on the cavity 121.

[0066] In this embodiment, the shape of the cavity 121 is pear-shaped. In other embodiments, the shape of the cavity 121 can also be spherical (see Figure 7 ), ellipsoid or cone (see Figure 8 ).

[0067] In this embodiment, a circular base 14 is provided below the bottle body 12, and the diameter of the base 14 is larger than the maximum diameter of the transverse section of the cavity 121. The shape and size of the base 14 can be selected according to actual conditions to ensure that the sample preparation device for quantitative detection can stand stably on the operating table during use and is not easy to tip over.

[0068] In other embodiments, if the bottom of the bottle body 12 is provided with a cavity 121, the area of ​​the lower surface of the cavity 121 is large enough to serve as the base 14, and there is no need to additionally provide the base 14 (see Figure 9 ). At this time, the volume scale value of the bottom surface of the cavity 121 is "0", and the volume scale values ​​gradually increase from bottom to top.

[0069] In this embodiment, the sealing component 2 is a sealing cover. In other embodiments, the sealing component 2 can also be a sealing plug inserted into the bottle mouth 11 of the quantitative bottle 1.

[0070] In this embodiment, the connection port 21, the main body 22 and the liquid outlet pipe 23 are integrally formed. In other embodiments, the connection port 21, the main body 22 and the liquid outlet pipe 23 are detachably sealed.

[0071] In this embodiment, the inner side of the connection port 21 of the sealing assembly 2 is a ground joint, and the outer side of the bottle mouth 11 of the volumetric flask 1 is a ground joint. The connection port 21 is sleeved on the outer side of the bottle mouth 11, and the two are hermetically connected. This structural arrangement has a better sealing effect, and when the sample preparation device for quantitative detection is inverted, the liquid is not likely to leak out. In other embodiments, the bottle mouth 11 can be sleeved on the outer side of the connection port 21. In other embodiments, the connection port 21 and the bottle mouth 11 can also be hermetically connected by means of screw threads, bayonet joints or sealing rings.

[0072] In this embodiment, the connection port 21 of the sealing assembly 2 and the bottle mouth 11 of the volumetric flask 1 are directly hermetically connected. In other embodiments, when the sizes of the connection port 21 of the sealing assembly 2 and the bottle mouth 11 of the volumetric flask 1 do not match and they cannot be directly hermetically connected, a adapter can be used to hermetically connect the connection port 21 and the bottle mouth 11.

[0073] In this embodiment, the main body 22 has a cavity structure. One end close to the connection port 21 is cylindrical, and one end close to the liquid outlet pipe 23 is conical. In other embodiments, the main body 22 can also be conical or cylindrical.

[0074] In this embodiment, the constant pressure tube 25 is detachably and hermetically connected to the ventilation port 24. In other embodiments, the constant pressure tube 25 and the ventilation port 24 can be integrally formed (see Figure 6 ) or fixedly connected.

[0075] In this embodiment, the ventilation port 24 extends in the direction of the connection port 21 and is provided with a first connection portion 28. The first connection portion 28 is integrally formed with the ventilation port 24, and the constant pressure tube 25 is detachably and hermetically connected to the first connection portion 28.

[0076] In this embodiment, the constant pressure tube 25 and the first connection portion 28 are hermetically connected by screw threads. In other embodiments, the constant pressure tube 25 and the first connection portion 28 can also be hermetically connected by bayonet joints, ground joints or sealing rings.

[0077] In this embodiment, the seal 26 is a sealing plug, which is inserted into the ventilation port 24 to seal the ventilation port 24. The seal 26 and the ventilation port 24 are hermetically connected by a ground joint. In other embodiments, the seal 26 and the ventilation port 24 can be hermetically connected by screw threads, bayonet joints or sealing rings. For example, in one embodiment (see Figure 10 ), the seal 26 is a sealing cap. The ventilation port 24 extends in the direction away from the connection port 21 and is provided with a second connection portion 29. The second connection portion 29 is integrally formed with the ventilation port 24. The second connection portion 29 is communicated with the constant pressure tube 25. The seal 26 and the second connection portion 29 are hermetically connected by screw threads. In this embodiment, the sealing effect of the seal 26 is more ideal, and when the sample preparation device for quantitative detection is inverted, the seal 26 is not likely to fall off, making it more convenient to use.

[0078] In this embodiment, after the metering flask 1 and the sealing assembly 2 are assembled, the constant pressure tube 25 extends into the metering flask 1 and reaches the bottom of the flask. In other embodiments, the length of the constant pressure tube 25 can be conventionally selected according to the volume of the liquid in the metering flask 1. When the sample preparation device for quantitative detection is inverted, it is only necessary to ensure that the end of the constant pressure tube 25 close to the bottom of the metering flask 1 is above the liquid level.

[0079] In this embodiment, the liquid outlet valve 27 is a stopcock valve, and the stopcock valve has a channel for liquid flow. Figure 3 Fig. is the state diagram when the stopcock is open. When the stopcock is in the open state, the channel for liquid flow communicates with the liquid outlet pipe 23.

[0080] In this embodiment, a drainage bevel is provided at the end of the liquid outlet pipe 23 away from the main body 22.

[0081] In this embodiment, the sample preparation device for quantitative detection further includes a connecting clip 3 for tightly connecting and fixing the connecting port 21 and the bottle mouth 11 together. Setting the connecting clip 3 can, on the one hand, make the connection between the connecting port 21 and the bottle mouth 11 tighter and prevent liquid leakage; on the other hand, when the sample preparation device for quantitative detection is inverted, it can prevent the sealing assembly 2 from falling off, making it safer and more convenient to use.

[0082] When the sample preparation device for quantitative detection of the present utility model is in use, the required volume of reaction liquid is added to the metering flask 1 according to the volume scale 13 on the metering flask 1; after adding, the sealing member 26 is hermetically connected to the vent port 24, and the connecting port 21 on the sealing assembly 2 and the bottle mouth 11 on the metering flask 1 are hermetically connected. At this time, the constant pressure tube 25 can be not installed, and it is shaken for mixing reaction. If gas is generated or heat is released during the mixing reaction, the liquid outlet valve 27 can be opened to discharge the gas or balance the internal and external pressures from the liquid outlet pipe 23; for the sample preparation process that requires dilution or extraction, after the reaction, the sealing assembly 2 is removed, and the diluent or extractant is added to the metering flask 1. The addition amount can be determined according to the volume scale 13 on the bottle body 12 or the cavity 121. To obtain the lower layer extractant, the constant pressure tube 25 is installed to ensure that the constant pressure tube 25 is hermetically connected to the first connecting portion 28, and at the same time, it is also necessary to ensure that the sealing member 26 is hermetically connected to the vent port 24 to prevent liquid from entering the constant pressure tube 25 when the constant pressure tube 25 is in the metering flask 1; after the constant pressure tube 25 is installed, the connecting port 21 on the sealing assembly 2 and the bottle mouth 11 on the metering flask 1 are hermetically connected. After shaking and extracting, the connecting clip 3 is installed, and the sample preparation device for quantitative detection is inverted. During the inversion process, the end of the constant pressure tube 25 close to the bottom of the metering flask 1 should be quickly above the liquid level as much as possible to prevent the liquid in the metering flask 1 from entering the constant pressure tube 25. After inversion, the sealing member 26 is removed to make the internal and external pressures of the device the same. After the liquid separation is completed, the test solution is released from the liquid outlet pipe 23.

[0083] The sample preparation device for quantitative detection of the present utility model can also handle detections that do not require extraction or detections where the test solution to be detected is located in the upper layer after extraction. During the use process, the constant pressure tube 25 can be not used. After the mixing reaction, the sealing assembly 2 is opened, and the upper-layer test solution can be directly sucked with a dropper.

[0084] Although the present application has been disclosed above through the description of specific embodiments of the present application, it should be understood that those skilled in the art can design various modifications, improvements, or equivalents to the present application within the spirit and scope of the appended solutions. These modifications, improvements, or equivalents should also be considered to be included within the scope claimed by the present application.

Claims

1. A sample preparation device for quantitative detection, characterized in that, It includes a metering bottle and a sealing assembly; the metering bottle includes a bottle mouth and a bottle body; the sealing assembly includes a connection port, a main body, and a liquid outlet pipe; the connection port, the main body, and the liquid outlet pipe are integrated as a whole; the connection port and the bottle mouth are detachably and sealingly connected; an air vent is provided on the main body, and a constant pressure pipe extends from the air vent towards the connection port direction, and the constant pressure pipe passes through the connection port; the sealing assembly further includes a sealing member for sealing the air vent; a liquid outlet valve is provided on the liquid outlet pipe.

2. The sample preparation device for quantitative detection according to claim 1, characterized in that, The sample preparation device for quantitative detection satisfies at least one of the following conditions (1) to (6): (1) The shape of the bottle body is a hollow cylinder. (2) The material of the bottle body is glass or polytetrafluoroethylene. (3) The color of the bottle body is transparent or brown. (4) Volume scales are provided on the bottle body. (5) At least one cavity is provided on the bottle body. (6) A base is provided below the bottle body.

3. The sample preparation device for quantitative detection according to claim 2, characterized in that, The sample preparation device for quantitative detection satisfies at least one of the following conditions (1) to (5): (1) The shape of the bottle body is a hollow cylinder or a hollow cuboid. (2) The cavity is provided in the middle part or the lower part of the bottle body. (3) Volume scales are provided on the cavity. (4) The shape of the cavity is spherical, ellipsoidal, conical, or pear-shaped. (5) The shape of the base is circular or square.

4. The sample preparation device for quantitative detection according to claim 3, wherein, At least one cavity is provided in the middle part of the bottle body, and volume scales are provided on the bottle body below the cavity and on the bottle body above the cavity.

5. The sample preparation device for quantitative detection according to claim 1, wherein The sample preparation device for quantitative detection satisfies at least one of the following conditions (1) to (8): (1) The sealing assembly is selected from a sealing cap or a sealing plug; (2) The sealing connection method between the connection port and the bottle mouth is selected from screw thread, bayonet, ground joint, or sealing ring. (3) The sample preparation device for quantitative detection further includes an adapter, and the connection port and the bottle mouth are detachably and sealingly connected through the adapter. (4) The main body is a cavity structure. (5) The main body is conical, cylindrical, or cylindrical at one end close to the connection port and conical at one end close to the liquid outlet pipe. (6) The constant pressure pipe is integrally formed with, fixedly connected to, or detachably and sealingly connected to the air vent. (7) The sealing connection method between the sealing member and the air vent is screw thread, bayonet, ground joint, or sealing ring. (8) The sealing member is a sealing plug or a sealing cap.

6. The sample preparation device for quantitative detection according to claim 5, characterized in that, A first connection part extends from the air vent towards the connection port direction, the first connection part is integrally formed with the air vent, and the constant pressure pipe is detachably and sealingly connected to the first connection part.

7. The sample preparation device for quantitative detection according to claim 6, wherein, The sealing connection method between the constant pressure pipe and the first connection part is screw thread, bayonet, ground joint, or sealing ring.

8. The sample preparation device for quantitative detection according to claim 5, wherein A second connection part extends from the air vent in a direction away from the connection port, the sealing member is detachably and sealingly connected to the second connection part, and the second connection part is communicated with the constant pressure pipe.

9. The sample preparation device for quantitative detection according to any one of claims 1 to 8, characterized in that, The sample preparation device for quantitative detection satisfies at least one of the following conditions (1) to (3): (1) After the metering bottle and the sealing assembly are assembled, the constant pressure pipe extends into the metering bottle. (2) The liquid outlet valve is a stopcock valve. (3) The sample preparation device for quantitative detection further includes a connecting clip for tightly connecting and fixing the connecting port and the bottle mouth together.

10. The sample preparation device for quantitative detection according to claim 9, characterized in that, The constant pressure tube extends to the bottom of the quantitative bottle.