Air pressure cabin for simulating animal test in low-pressure environment

Abstract

The utility model relates to the technical field of animal tests in low-pressure environments, in particular to an air pressure chamber for simulating animal tests in low-pressure environments, which comprises an air pressure chamber, belt pulleys are rotatably connected to two ends of the inner wall of the air pressure chamber, and a conveying belt is in transmission connection to the surfaces of the two belt pulleys. A transparent plate is hinged to the top end of the air pressure cabin through a hinge; the blocking mechanism is arranged in the air pressure cabin; the blocking mechanism comprises two check rings fixedly connected to the inner wall of the air pressure cabin, one side of each check ring makes contact with one side of the conveying belt, and the two ends of the inner wall of the air pressure cabin are slidably connected with check blocks. According to the device, through the check ring and the check block, the moving space of the white mouse on the inner wall of the gas-liquid cabin is limited, compared with the existing mode that the white mouse can move away from the conveying belt and enter the pipeline cavity, the white mouse in the scheme is not separated from the surface of the conveying belt all the time in the moving process, and the white mouse in the air pressure cabin is more convenient to take.

Description

Technical Field

[0001] The utility model relates to the technical field of animal experiments under low - pressure environment, and particularly to a pressure chamber for simulating animal experiments under low - pressure environment. Background Technique

[0002] The pressure chamber for animal experiments is a device used to simulate different air - pressure environments to study the physiological and biochemical reactions of animals under various air - pressure conditions. In order to study the effects on animals under low air - pressure, the inside of the pressure chamber is usually set to low air - pressure so that the animals are in a low - pressure environment to study the effects of air - pressure changes on the respiratory system and chronic lung diseases of animals.

[0003] After retrieval, the Chinese patent "A Hypoxic and Hypobaric Animal Experiment Chamber" with the authorization announcement number "CN216725061U" uses a sealing plate, an observation window, a cylinder, a conveyor belt and a connecting part. The white rats are placed on the conveyor belt inside the cylinder to simulate the low - pressure environment to observe the changes of the white rats. After the test, the white rats in the cylinder are taken out by opening the sealing plate, and the operation of putting in and taking out the white rats is simple.

[0004] There is a large gap between the above - mentioned conveyor belt and the inner wall of the cylinder, and it is easy for the white rats to run out of the conveyor belt or enter the chamber of the connecting part, which further increases the difficulty of taking out the white rats in the cylinder.

[0005] Therefore, a pressure chamber for simulating animal experiments under low - pressure environment is proposed to solve the above problems. Content of the Utility Model

[0006] The purpose of the utility model is to provide a pressure chamber for simulating animal experiments under low - pressure environment to solve the above problems and improve the problem of difficult taking of white rats in the cylinder.

[0007] The utility model realizes the above - mentioned purpose through the following technical solutions. A pressure chamber for simulating animal experiments under low - pressure environment includes: a pressure chamber, at both ends of the inner wall of the pressure chamber, there are rotatably connected pulley wheels, and the surfaces of the two pulley wheels are drivingly connected with a conveyor belt. The top of the pressure chamber is hinged with a transparent plate through a hinge; a blocking mechanism, the blocking mechanism is arranged inside the pressure chamber; wherein, the blocking mechanism includes two retaining rings fixedly connected to the inner wall of the pressure chamber, one side of the retaining ring contacts one side of the conveyor belt, both ends of the inner wall of the pressure chamber are slidably connected with a blocking block, the upper end of the surface of the pressure chamber is rotatably connected with a bidirectional lead screw, the upper end of the surface of the blocking block is threadedly connected to the surface of the bidirectional lead screw, and a series of equally - spaced through holes are opened at one end of the blocking block. Through the retaining ring and the blocking block, the moving space of the white rats on the inner wall of the air - liquid chamber is restricted. Compared with the existing situation where white rats can move away from the conveyor belt and enter the pipeline chamber, in this scheme, the white rats never leave the surface of the conveyor belt during movement, and it is more convenient to take out the white rats in the pressure chamber.

[0008] Preferably, one end of the transparent plate is fixedly connected to a first gear, the surface of the first gear is meshedly connected to a second gear, and the surface of the bidirectional screw is fixedly connected to the inner wall of the second gear. Through the first gear, the second gear and the bidirectional screw, the transparent plate drives the two blocks to approach each other during the flipping, thereby reducing the activity space of the white mouse, thereby reducing the difficulty of taking the white mouse in the air pressure cabin.

[0009] Preferably, a vacuum pump is provided at the lower end of the surface of the pressure cabin, and one side of the vacuum pump is connected to a corrugated hose.

[0010] Preferably, a mounting ring is provided on the surface of the corrugated hose, and the inner side of the mounting ring is threadedly connected to the surface of the air pressure cabin.

[0011] Preferably, both ends of the block are fixedly connected with compression pads, and the other side of the compression pad is fixedly connected to the upper end of the inner wall of the pressure cabin. The compression pad can block the upper end of the inner wall of the pressure cabin, prevent the outside air from flowing into the pressure cabin through the opening at the upper end of the inner wall of the pressure cabin, and ensure that the pressure cabin is in a suitable negative pressure environment.

[0012] Preferably, a ball is rollingly connected to the bottom of the stopper, and the surface of the ball is rollingly connected to the surface of the conveyor belt. The ball reduces the friction at the contact point between the stopper and the conveyor belt.

[0013] Preferably, a support rod is fixedly connected to the lower end of the inner wall of the air pressure cabin, and the inner surface of the conveyor belt contacts the surface of the support rod. The support rod supports the surface of the conveyor belt, avoids collapse in the middle of the conveyor belt, and ensures that the rat can walk normally on the conveyor belt.

[0014] Preferably, a sealing bearing is fixedly connected to the inner wall of the mounting ring, and the inner edge of the sealing bearing is fixedly connected to the surface of the corrugated hose. Through the sealing bearing, the mounting ring thread is installed on one end of the pressure cabin surface without driving the corrugated hose to rotate, thereby reducing the wear of the corrugated hose.

[0015] The beneficial effects of the utility model are:

[0016] 1. The retaining ring and the block are used to limit the activity space of the rat on the inner wall of the gas-liquid tank. Compared with the existing rat that can move away from the conveyor belt and enter the pipe chamber, the rat in this solution does not leave the conveyor belt surface during movement, making it more convenient to take the rat in the pressure tank;

[0017] 2. Through the first gear, the second gear and the bidirectional screw rod, the transparent plate drives the two blocks to approach each other during the flipping, thereby reducing the activity space of the white mouse, thereby reducing the difficulty of taking the white mouse in the pressure cabin. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 Schematic diagram of the overall structure of the present utility model;

[0019] Figure 2 Explosion diagram of the corrugated hose and the mounting ring of the present utility model;

[0020] Figure 3 Schematic diagram of the structure of the blocking mechanism of the present utility model;

[0021] Figure 4 is Figure 3 The enlarged view of A in

[0022] In the figure: 1, air pressure chamber; 2, pulley; 3, conveyor belt; 4, transparent plate; 5, blocking mechanism; 51, retaining ring; 52, block; 53, through hole; 54, bidirectional lead screw; 55, first gear; 56, second gear; 57, compression pad; 58, ball; 59, support rod; 510, vacuum pump; 511, corrugated hose; 512, mounting ring. Specific implementation manner

[0023] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0024] During specific implementation: As Figures 1-4 shown, an air pressure chamber for simulating animal experiments in a low-pressure environment includes: an air pressure chamber 1, the two ends of the inner wall of the air pressure chamber 1 are rotatably connected with pulleys 2, the surfaces of the two pulleys 2 are drivingly connected with a conveyor belt 3, and the top end of the air pressure chamber 1 is hinged with a transparent plate 4 through a hinge; a blocking mechanism 5, the blocking mechanism 5 is arranged inside the air pressure chamber 1; wherein, the blocking mechanism 5 includes two retaining rings 51 fixedly connected to the inner wall of the air pressure chamber 1, one side of the retaining ring 51 contacts one side of the conveyor belt 3, the two ends of the inner wall of the air pressure chamber 1 are slidably connected with blocks 52, the upper end of the surface of the air pressure chamber 1 is rotatably connected with a bidirectional lead screw 54, the upper end of the surface of the block 52 is threadedly connected to the surface of the bidirectional lead screw 54, and the end of the block 52 is provided with equally distributed through holes 53, the lower end of the surface of the air pressure chamber 1 is provided with a vacuum pump 510, one side of the vacuum pump 510 is communicated with a corrugated hose 511, the surface of the corrugated hose 511 is provided with a mounting ring 512, the inner side of the mounting ring 512 is threadedly connected to the surface of the air pressure chamber 1, and the inner wall of the mounting ring 512 is fixedly connected with a sealing bearing, and the inner edge of the sealing bearing is fixedly connected to the surface of the corrugated hose 511.

[0025] Both ends of the pressure chamber 1 are threadedly connected with sealing rings. The inner side of the mounting ring 512 is threadedly connected to the surface of one of the sealing rings. One end of the other sealing ring is provided with a deoxidizing cylinder, and the inside of the deoxidizing cylinder is filled with deoxidizing materials such as deoxidants. The surface of the pressure chamber 1 is fixedly connected with a first servo motor. The output shaft of the first servo motor is fixedly connected to one end of one of the pulleys 2. The lower end of the surface of the pressure chamber 1 is provided with a support platform, and the surface of the pressure chamber 1 is rotatably connected to the upper end of the surface of the support platform. The bottom of the vacuum pump 510 is fixedly connected to the top of the support platform. The front end of the support platform is fixedly connected with a second servo motor. The output shaft of the second servo motor is fixedly connected to the surface of the pressure chamber 1. The bottom of the transparent plate 4 is fixedly connected with a silica gel ring, and the silica gel ring is closely attached to the upper opening of the surface of the pressure chamber 1. The top of the transparent plate 4 is embedded with a first magnet, and the upper end of the surface of the pressure chamber 1 is embedded with a second magnet. The first magnet and the second magnet attract each other with opposite poles. The upper end of the surface of the pressure chamber 1 is provided with an oxygen content detection probe, a pressure sensor and a pressure relief pipe. An electric control valve is embedded in the surface of the pressure relief pipe.

[0026] When it is necessary to study the respiratory system of white rats and chronic lung diseases in a low-pressure environment, open the transparent plate 4 to open the upper opening of the surface of the pressure chamber 1. When the transparent plate 4 is opened, it drives the bidirectional lead screw 54 to rotate. The rotation of the bidirectional lead screw 54 drives the two stoppers 52 to approach each other. At this time, put the white rats on the conveyor belt 3, push the transparent plate 4, and make the transparent plate 4 magnetically positioned at the upper opening of the surface of the pressure chamber 1. When the transparent plate 4 is flipped, it drives the two stoppers 52 to move away from each other to a suitable position through the bidirectional lead screw 54, restricting the activity range of the white rats.

[0027] Manually turn on the vacuum pump 510. The vacuum pump 510 extracts some air in the pressure chamber 1 through the corrugated hose 511, gradually reducing the pressure in the pressure chamber 1 to form a low-pressure environment inside. After detecting through the pressure sensor that a suitable low-pressure environment is reached in the pressure chamber 1, manually turn off the vacuum pump 510. At this time, the conveyor belt 3 can be driven to move, so that the white rats walk on the conveyor belt 3. The experimenter needs to monitor the respiratory rate, blood oxygen saturation and other relevant physiological parameters of the animals in real time and record them to study the impact of air pressure changes on the respiratory system and chronic lung diseases of the animals. Adjust the air pressure and oxygen concentration in the chamber according to the monitoring data to avoid negative impacts on the health of the animals.

[0028] As Figure 4 shown, one end of the transparent plate 4 is fixedly connected with a first gear 55. The surface of the first gear 55 is meshed with a second gear 56. The surface of the bidirectional lead screw 54 is fixedly connected to the inner wall of the second gear 56.

[0029] As Figure 4 shown, both ends of the stopper 52 are fixedly connected with compression pads 57. The other side of the compression pad 57 is fixedly connected to the upper inner wall of the pressure chamber 1. The compression pad 57 is a silica gel component.

[0030] As Figure 3 shown, a ball 58 is rotatably connected to the bottom of the stopper 52, and the surface of the ball 58 is rotatably connected to the surface of the conveyor belt 3. A support rod 59 is fixedly connected to the lower end of the inner wall of the air pressure chamber 1, and the inner surface of the conveyor belt 3 contacts the surface of the support rod 59.

[0031] When the present utility model is in use, the transparent plate 4 is opened to open the upper opening of the surface of the air pressure chamber 1. When the transparent plate 4 is opened, it drives the first gear 55 to rotate. Since the diameter of the first gear 55 is larger than that of the second gear 56, and the specific gear diameter ratio is selected according to actual needs, the first gear 55 drives the second gear 56 to rotate rapidly. The rapid rotation of the second gear 56 drives the two stoppers 52 to approach each other through the bidirectional lead screw 54, so that the activity space of the white rat on the conveyor belt 3 is gradually reduced. At this time, the upper opening of the surface of the air pressure chamber 1 is open, and the tester can quickly take the white rat on the conveyor belt 3.

[0032] It should be noted that in the above description, the air pressure chamber 1, the vacuum pump 510, the first servo motor, the second servo motor, the sealed bearing, the oxygen content detection probe, the air pressure sensor, the pressure relief pipe, the electric control valve, etc. are all devices with relatively mature applications in the prior art. The specific models can be selected according to actual needs. At the same time, the power supply for the vacuum pump 510, the first servo motor, the second servo motor, the oxygen content detection probe, the air pressure sensor and the electric control valve can be powered by an internal power supply or by the mains power supply. The specific power supply method is selected according to the situation and will not be elaborated here.

[0033] In addition, it should be understood that although this specification is described according to the embodiments, not each embodiment only contains an independent technical solution. This narrative way of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A pressure cabin for animal experiments simulating a low-pressure environment, characterized in that, Including: A pressure chamber (1), at both ends of the inner wall of the pressure chamber (1), there are rotatably connected pulleys (2), and the surfaces of the two pulleys (2) are drivingly connected with a conveyor belt (3), and the top end of the pressure chamber (1) is hinged with a transparent plate (4) through a hinge; A blocking mechanism (5), the blocking mechanism (5) is arranged inside the pressure chamber (1); Among them, the blocking mechanism (5) includes two retaining rings (51) fixedly connected to the inner wall of the pressure chamber (1), one side of the retaining ring (51) contacts one side of the conveyor belt (3), both ends of the inner wall of the pressure chamber (1) are slidably connected with a blocking block (52), the upper end of the surface of the pressure chamber (1) is rotatably connected with a bidirectional lead screw (54), the upper end of the surface of the blocking block (52) is threadedly connected to the surface of the bidirectional lead screw (54), and through holes (53) are arranged in an equal-column distribution at one end of the blocking block (52).

2. The pressure chamber for animal experiments simulating a low-pressure environment according to claim 1, wherein: One end of the transparent plate (4) is fixedly connected with a first gear (55), the surface of the first gear (55) is meshingly connected with a second gear (56), and the surface of the bidirectional lead screw (54) is fixedly connected to the inner wall of the second gear (56).

3. The pressure chamber for animal experiments simulating a low-pressure environment according to claim 1, characterized in that: The lower end of the surface of the pressure chamber (1) is provided with a vacuum pump (510), and one side of the vacuum pump (510) is communicated with a corrugated hose (511).

4. A pressure chamber for animal experiments simulating a low-pressure environment according to claim 3, characterized in that: The surface of the corrugated hose (511) is provided with a mounting ring (512), and the inner side of the mounting ring (512) is threadedly connected to the surface of the pressure chamber (1).

5. A pressure chamber for animal experiments simulating a low-pressure environment according to claim 1, characterized in that: Both ends of the blocking block (52) are fixedly connected with compression pads (57), and the other side of the compression pads (57) is fixedly connected to the upper end of the inner wall of the pressure chamber (1).

6. The pressure chamber for animal experiments in a simulated low-pressure environment according to claim 1, characterized in that: The bottom of the blocking block (52) is rollingly connected with a ball (58), and the surface of the ball (58) is rollingly connected to the surface of the conveyor belt (3).

7. The pressure chamber for animal experiments simulating a low-pressure environment according to claim 1, characterized in that: The lower end of the inner wall of the pressure chamber (1) is fixedly connected with a support rod (59), and the inner surface of the conveyor belt (3) contacts the surface of the support rod (59).

8. A pressure chamber for simulating low-pressure environment animal experiments according to claim 4, characterized in that: The inner wall of the mounting ring (512) is fixedly connected with a sealing bearing, and the inner edge of the sealing bearing is fixedly connected to the surface of the corrugated hose (511).

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